Dual contribution to amplification in the mammalian inner ear

The inner ear achieves a wide dynamic range of responsiveness by mechanically amplifying weak sounds. The enormous mechanical gain reported for the mammalian cochlea, which exceeds a factor of 4,000, poses a challenge for theory. Here we show how such a large gain can result from an interaction between amplification by low-gain hair bundles and a pressure wave: hair bundles can amplify both their displacement per locally applied pressure and the pressure wave itself. A recently proposed ratchet mechanism, in which hair-bundle forces do not feed back on the pressure wave, delineates the two effects. Our analytical calculations with a WKB approximation agree with numerical solutions.Comment: 4 pages, 4 figure

Social Medicine in Latin America and its multiple viewpoints on qualitative research

Objectives: To explore the relationship between social medicine and qualitative research, and the positions adopted by the former with respect to the latter

THE MEDIATING EFFECT OF WORK COMMITMENT ON THE RELATIONSHIP BETWEEN FAMILY RELATIONS AND MARITAL SATISFACTION OF SOCIAL WORKERS

The purpose of this study was to determine the mediating effect of work commitment on the relationship between family relations and marital satisfaction of married social workers. Utilizing quantitative, non-experimental design via correlational technique, and mediation analysis data were obtained from 300 married social workers under Region XI. The researcher utilized a stratified sampling technique in selecting the study participants and survey mode of data collection through standardized questionnaires.  The researcher also utilized the statistical tools mean, Pearson r and Med-graph using Sobel z-test to analyse data gathered.  From the results of the study, it was found out that for work commitment and family relations obtained a very high and while marital satisfaction of married social workers got a high level. Also, results revealed that significant relationships exist between family relations and work commitment, between work commitment and marital satisfaction and between family relations and marital satisfaction of married social workers. Further, it was revealed that work commitment partially mediates the relationship between family relations and marital satisfaction of married social workers.  Article visualizations

Neoteetonics of the eastern border of the Madrid basin

[Abstract] An analysis ofthe neotectonic activity and the current stress state of the eastern border of Madrid Basin has been carried ont using structural-methods (fault population analysis), as well as seismological methods. Two stress tensors have been established: - Tensor 1: with a N1500E shortening trend, characterized mainly by strikeslip faults. This tensor corresponds to the «Guadarrama» stress field (Capote et al., 1990), wihch causes the Central System structure; dated middle Aragonian -lower Pleistocene in the eastern border ofMadrid Basin (Muñoz Martín, 1993). - Tensor 2: dated post-Iower Pleistocene, with a N150° E extension trend, characterized basically by normal faults. Actual stress tensor deduced focal mechanisms by the seismological method is compatible with the paleostress field deduced for the middle-Iower Pleistocene (tensor 2)

On the relation between virial coefficients and the close-packing of hard disks and hard spheres

The question of whether the known virial coefficients are enough to determine the packing fraction $\eta_\infty$ at which the fluid equation of state of a hard-sphere fluid diverges is addressed. It is found that the information derived from the direct Pad\'e approximants to the compressibility factor constructed with the virial coefficients is inconclusive. An alternative approach is proposed which makes use of the same virial coefficients and of the equation of state in a form where the packing fraction is explicitly given as a function of the pressure. The results of this approach both for hard-disk and hard-sphere fluids, which can straightforwardly accommodate higher virial coefficients when available, lends support to the conjecture that $\eta_\infty$ is equal to the maximum packing fraction corresponding to an ordered crystalline structure.Comment: 10 pages, 6 figures; v2: discussion about hard-square and hard-hexagon systems on a lattice added; five new reference

Spin configuration in a frustrated ferromagnetic/antiferromagnetic thin film system

We have studied the magnetic configuration in ultrathin antiferromagnetic Mn films grown around monoatomic steps on an Fe(001) surface by spin-polarized scanning tunneling microscopy/spectroscopy and ab-initio-parametrized self-consistent real-space tight binding calculations in which the spin quantization axis is independent for each site thus allowing noncollinear magnetism. Mn grown on Fe(001) presents a layered antiferromagnetic structure. In the regions where the Mn films overgrows Fe steps the magnetization of the surface layer is reversed across the steps. Around these defects a frustration of the antiferromagnetic order occurs. Due to the weakened magnetic coupling at the central Mn layers, the amount of frustration is smaller than in Cr and the width of the wall induced by the step does not change with the thickness, at least for coverages up to seven monolayers.Comment: 10 pages, 5 figure

Litiasis urológicas en la provincia de Huelva

Se ha realizado el estudio de la frecuencia de los componentes minerales en 500 casos de litiasis urológicas, así como la incidencia de éstas y los cita los componentes de acuerdo con la edad y sexo. Se observa que la mayor parte de los casos se deben a oxalato cálcico, seguido de ácido úrico, siendo más frecuentes las litiasis entre los 40 y 60 años, presentándose en número ligeramente mayor en el sexo masculino.A survey has been made about the frecuency of mineral compounds in 500 cases of urological lithiasis as well as the incidence of these and the aforementioned compounds accordign to age and sexo Most of the cases are due to calcium oxalate, uric acid was founf as the second compound. Lithiasis frecuency is higher in persons between forty and sixty years and slighty bigger in males

Improving Deep Brain Stimulation Electrode Performance in vivo Through Use of Conductive Hydrogel Coatings

Active implantable neurological devices like deep brain stimulators have been used over the past few decades to treat movement disorders such as those in people with Parkinson’s disease and more recently, in psychiatric conditions like obsessive compulsive disorder. Electrode-tissue interfaces that support safe and effective targeting of specific brain regions are critical to success of these devices. Development of directional electrodes that activate smaller volumes of brain tissue requires electrodes to operate safely with higher charge densities. Coatings such as conductive hydrogels (CHs) provide lower impedances and higher charge injection limits (CILs) than standard platinum electrodes and support safer application of smaller electrode sizes. The aim of this study was to examine the chronic in vivo performance of a new low swelling CH coating that supports higher safe charge densities than traditional platinum electrodes. A range of hydrogel blends were engineered and their swelling and electrical performance compared. Electrochemical performance and stability of high and low swelling formulations were compared during insertion into a model brain in vitro and the formulation with lower swelling characteristics was chosen for the in vivo study. CH-coated or uncoated Pt electrode arrays were implanted into the brains of 14 rats, and their electrochemical performance was tested weekly for 8 weeks. Tissue response and neural survival was assessed histologically following electrode array removal. CH coating resulted in significantly lower voltage transient impedance, higher CIL, lower electrochemical impedance spectroscopy, and higher charge storage capacity compared to uncoated Pt electrodes in vivo, and this advantage was maintained over the 8-week implantation. There was no significant difference in evoked potential thresholds, signal-to-noise ratio, tissue response or neural survival between CH-coated and uncoated Pt groups. The significant electrochemical advantage and stability of CH coating in the brain supports the suitability of this coating technology for future development of smaller, higher fidelity electrode arrays with higher charge density requirement

The Active Traveling Wave in the Cochlea

A sound stimulus entering the inner ear excites a deformation of the basilar membrane which travels along the cochlea towards the apex. It is well established that this wave-like disturbance is amplified by an active system. Recently, it has been proposed that the active system consists of a set of self-tuned critical oscillators which automatically operate at an oscillatory instability. Here, we show how the concepts of a traveling wave and of self-tuned critical oscillators can be combined to describe the nonlinear wave in the cochlea.Comment: 5 pages, 2 figure

Stabilization of a Large Paleo-Landslide Reactivated Because of the Works to Install a New Ski Lift in Formigal Skiing Resort

The paper presents the study and stabilization of a paleo-landslide reactivated because of the excavation works carried out at its foot to construct a new lift in Formigal skiing resort. Inclinometers were installed and surface movements were controlled by GPS techniques in order to analyse the sliding surface and to define the stabilization measures to undertake. The data obtained from the instrumentation was used to perform a back-analysis that allowed to determine the kinematics of the movement as well as to define the appropriate stabilization measures. Presently, the evolution of the movement is controlled by GPS