A Systematic Review of Refugee Women’s Reproductive Health

Resettling refugee women may be at greater risk than other women for several harmful reproductive health outcomes as a result of their migration experience. The objective of this study was to determine differences in reproductive health status between refugee women in countries of resettlement and non-refugee counterparts. A systematic review of the literature culled from five electronic databases and web searching of international agencies and academic centres focusing on refugees was conducted. Of the forty-one high quality studies identified, fourteen looked at refugees exclusively; only nine of the fourteen focused on the reproductive health of refugees; six of the nine directly compared refugee to non-refugee women’s health. There is a paucity of populationbased data to support or refute claims of greater reproductive health risks for resettling refugee women.Les femmes réfugiées en situation de réétablissement pourraient bien être plus susceptibles que d’autres femmes de souffrir d’un certain nombre de conséquences néfastes en matière de santé génésique suite à l’expérience de lamigration. Le but de cette étude était de cerner les différences entre le niveau de santé génésique des femmes réfugiées dans les pays de réétablissement et leurs congénères non-réfugiées. Pour ce faire, un examen systématique de la littérature provenant de cinq bases de données électroniques a été entrepris, ainsi que des recherches sur le Web d’agences et de centres académiques internationaux. Des 41 études de haut niveau identifiées, seules 9 de ces études se concentraient sur la santé génésique des réfugiées ; 6 de ces 9 études effectuaient une comparaison directe entre la santé des réfugiées et celle des non-réfugiées. Il existe en fait un manque de données démographiques qui permettraient de soutenir ou de rejeter l’affirmation selon laquelle les risques sont accrus en matière de santé génésique chez les femmes réfugiées en cours de réétablissement

The H-alpha and Infrared Star Formation Rates for the Nearby Field Galaxy Survey

We investigate the H-alpha and infrared star formation rate (SFR) diagnostics for galaxies in the Nearby Field Galaxy Survey (NFGS). For the 81 galaxies in our sample, we derive H-alpha fluxes (included here) from integrated spectra. There is a strong correlation between the ratio of far-infrared to optical luminosities L(FIR)/L(H-alpha) and the extinction E(B-V) measured with the Balmer decrement. Before reddening correction, the SFR(IR) and SFR(H-alpha) are related to each other by a power-law. Correction of the SFR(H-alpha) for extinction using the Balmer decrement and a classical reddening curve both reduces the scatter in the SFR(IR)-SFR(H-alpha) correlation and results in a much closer agreement (within ~10%) between the two SFR indicators. This SFR relationship spans 4 orders of magnitude and holds for all Hubble types with IRAS detections in the NFGS. A constant ratio between the SFR(IR) and SFR(H-alpha) for all Hubble types, including early types (S0-Sab), suggests that the IR emission in all of these objects results from a young stellar population.Comment: 23 pages, 5 figures, 1 table. Accepted for publication in the Astronomical Journal. V2: Important changes: IRAS fluxes updated. Only moderate and good quality IRAS FIR fluxes are now used, resulting in slight changes to the equations and figures. The IR and H-alpha SFRs now agree to within ~10%, rather than ~30% as quoted previousl

Chapter 2 Investigating waiting

Researching ‘waiting’ necessitates practices of attunement to multiple coexisting temporalities and careful processes for handling and holding the temporal material produced by these practices. In this chapter, we share some of what has been learned from experiments in ‘making time’ as a research practice, in which we have had to invent the relations needed to give the temporal a thinkable form. We bring together accounts from three collaborative projects about waiting in health settings, where waiting is fundamentally linked to practices of care. Each project sits within its own discipline (publicly-engaged literary studies, artistic practice-as-research, and psychosocial studies), leading researchers to experiment with different forms and concepts through which time as an ‘object’ might be attended to, grasped and indeed ‘made’ in the process

From Science Student to Scientist: Predictors and Outcomes of Heterogeneous Science Identity Trajectories in College

This 5-year longitudinal study investigates the development of science identity throughout college from an expectancy-value perspective. Specifically, heterogeneous developmental patterns of science identity across 4 years of college were examined using growth-mixture modeling. Gender, race/ethnicity, and competence beliefs (efficacy for science tasks, perceived competence in science) were modeled as antecedents, and participation in a science career after graduation was modeled as a distal outcome of these identity development trajectories. Three latent classes (High with Transitory Incline, Moderate-High and Stable, and Moderate-Low with Early Decline) were identified. Gender, race/ethnicity, and competence beliefs in the first year of college significantly predicted latent class membership. In addition, students in the two highest classes were significantly more likely to report being involved in science careers or science fields after college graduation than students in the Moderate-Low with Early Decline class

Loss of DNA polymerase zeta enhances spontaneous tumorigenesis.

Mammalian genomes encode at least 15 distinct DNA polymerases, functioning as specialists in DNA replication, DNA repair, recombination, or bypass of DNA damage. Although the DNA polymerase zeta (polzeta) catalytic subunit REV3L is important in defense against genotoxins, little is known of its biological function. This is because REV3L is essential during embryogenesis, unlike other translesion DNA polymerases. Outstanding questions include whether any adult cells are viable in the absence of polzeta and whether polzeta status influences tumorigenesis. REV3L-deficient cells have properties that could influence the development of neoplasia in opposing ways: markedly reduced damage-induced point mutagenesis and extensive chromosome instability. To answer these questions, Rev3L was conditionally deleted from tissues of adult mice using MMTV-Cre. Loss of REV3L was tolerated in epithelial tissues but not in the hematopoietic lineage. Thymic lymphomas in Tp53(-/-) Rev3L conditional mice occurred with decreased latency and higher incidence. The lymphomas were populated predominantly by Rev3L-null T cells, showing that loss of Rev3L can promote tumorigenesis. Remarkably, the tumors were frequently oligoclonal, consistent with accelerated genetic changes in the absence of Rev3L. Mammary tumors could also arise from Rev3L-deleted cells in both Tp53(+/+) and Tp53(+/-) backgrounds. Mammary tumors in Tp53(+/-) mice deleting Rev3L formed months earlier than mammary tumors in Tp53(+/-) control mice. Prominent preneoplastic changes in glandular tissue adjacent to these tumors occurred only in mice deleting Rev3L and were associated with increased tumor multiplicity. Polzeta is the only specialized DNA polymerase yet identified that inhibits spontaneous tumor development

Construct validity of the pictorial scale of perceived movement skill competence

Objectives: The Pictorial Scale of Perceived Movement Skill Competence (PMSC) assesses young children\u27s perceptions of movement skill competence: 12 perceived Fundamental Movement skills (FMS; based on the Test of Gross Motor Development 2nd edition TGMD-2) and six Active Play activities (e.g. cycling). The main study purpose was to assess whether children\u27s movement perception scores fit within the imposed constructs of Active Play and FMS by testing the latent structure and construct validity of the PMSC. Design: Construct validation study. Methods: Participants were part of the Melbourne Infant Feeding, Activity and Nutrition Trial (InFANT). The latent structure of the PMSC responses was tested through confirmatory factor analysis (CFA) and Bayesian Structural Equation Modeling (BSEM). Internal consistency was conducted using polychoric correlation-based alphas. Results: The 303 children (boys 53.1%, n = 161) were aged 4-5 years (M = 4.7, SD = 0.46). The final model had an 18 item 3-factor solution with good fit indices (using CFA and BSEM). Factors were: Active Play (Bike, Board Paddle, Climb, Skate/Blade, Scooter, and Swim), Object Control - Hand Skills (Bounce, Catch, Hit, Throw), and FMS skills with a leg action (Gallop, Hop, Jump, Leap, Run, Step Slide, Kick, Roll). Alpha reliability values were: Active Play (0.78), Object Control-Hand Skills (0.76) and FMS-Dynamic Leg (0.84). Conclusion: Young children can distinguish between movement perceptions. The factors reflect the hypothesized structure in terms of FMS being distinguished from Active Play. Further research should investigate how and if these constructs change in children over time

The President\u27s Emergency Plan for AIDS Relief (PEPFAR): A Social Work Ethical Analysis and Recommendations

The President\u27s Emergency Plan for AIDS Relief (PEPFAR) is the most recent international social program instituted by the U.S. Government to combat HIV/AIDS. Since its inception in 2003, this foreign policy initiative has dedicated $63 billion for HIV/AIDS prevention and treatment in foreign countries. Despite PEPFAR\u27s many accomplishments, it continues to promote controversial prevention strategies. This paper analyzes these prevention strategies, utilizing social work values as described in the NASW Code of Ethics. Policy, practice, and research implications are discussed

Continuing or temporarily stopping prestroke antihypertensive medication in acute stroke: an individual patient data meta-analysis

Over 50% of patients are already taking blood pressure–lowering therapy on hospital admission for acute stroke. An individual patient data meta-analysis from randomized controlled trials was undertaken to determine the effect of continuation versus temporarily stopping preexisting antihypertensive medication in acute stroke. Key databases were searched for trials against the following inclusion criteria: randomized design; stroke onset ≤48 hours; investigating the effect of continuation versus stopping prestroke antihypertensive medication; and follow-up of ≥2 weeks. Two randomized controlled trials were identified and included in this meta-analysis of individual patient data from 2860 patients with ≤48 hours of acute stroke. Risk of bias in each study was low. In adjusted logistic regression and multiple regression analyses (using random effects), we found no significant association between continuation of prestroke antihypertensive therapy (versus stopping) and risk of death or dependency at final follow-up: odds ratio 0.96 (95% confidence interval, 0.80–1.14). No significant associations were found between continuation (versus stopping) of therapy and secondary outcomes at final follow-up. Analyses for death and dependency in prespecified subgroups revealed no significant associations with continuation versus temporarily stopping therapy, with the exception of patients randomized ≤12 hours, in whom a difference favoring stopping treatment met statistical significance. We found no significant benefit with continuation of antihypertensive treatment in the acute stroke period. Therefore, there is no urgency to administer preexisting antihypertensive therapy in the first few hours or days after stroke, unless indicated for other comorbid conditions

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Kartoffelausgabe im Hof des städtischen Ernährungamte

Novel rat tail discitis model using bioluminescent Staphylococcus aureus

Management of spondylodiscitis is a challenging clinical problem requiring medical and surgical treatment strategies. The purpose of this study was to establish a rat model of spondylodiscitis that utilizes bioluminescent Staphylococcus aureus, thus permitting in-vivo surveillance of infection intensity. Inocula of the bioluminescent S. aureus strain XEN36 were created in concentrations of 102 CFU/0.1 mL, 104 CFU/0.1 mL, and 106 CFU/0.1 mL. Three groups of rats were injected with the bacteria in the most proximal intervertebral tail segment. The third most proximal tail segment was injected with saline as a control. Bioluminescence was measured at baseline, 3 days, and weekly for a total of 6 weeks. Detected bioluminescence for each group peaked at day three and returned to baseline at 21 days. The average intensity was highest for the experimental group injected with the most concentrated bacterial solution (106 CFU/0.1 mL). Radiographic analysis revealed loss of intervertebral disc space and evidence of osseous bridging. Saline injected spaces exhibited no decrease in intervertebral spacing as compared to distal sites. Histologic analysis revealed neutrophilic infiltrates, destruction of the annulus fibrosus and nucleus pulposus, destruction of vertebral endplates, and osseous bridging. Saline injected discs exhibited preserved annulus fibrosus and nucleus pulposus on histology. This study demonstrates that injection of bioluminescent S. aureus into the intervertebral disc of a rat tail is a viable animal model for spondylodiscitis research. This model allows for real-time, in-vivo quantification of infection intensity, which may decrease the number of animals required for infection studies of the intervertebral disc