Zappa-Sz\'ep products of semigroups and their C*-algebras

Zappa-Sz\'ep products of semigroups encompass both the self-similar group actions of Nekrashevych and the quasi-lattice-ordered groups of Nica. We use Li's construction of semigroup $C^*$-algebras to associate a $C^*$-algebra to Zappa-Sz\'ep products and give an explicit presentation of the algebra. We then define a quotient $C^*$-algebra that generalises the Cuntz-Pimsner algebras for self-similar actions. We indicate how known examples, previously viewed as distinct classes, fit into our unifying framework. We specifically discuss the Baumslag-Solitar groups, the binary adding machine, the semigroup $\mathbb{N}\rtimes\mathbb{N}^\times$, and the $ax+b$-semigroup $\mathbb{Z}\rtimes\mathbb{Z}^\times$

Safety Professional’s Perception of the Relationship Between Safety Management Systems and Safety Culture

The purpose of this qualitative study was to investigate the relationship between the elements/processes of safety management systems (SMSs) and their impact on safety culture at collegiate flight training institutions. Research questions addressed the following: different approaches to developing and implementing an SMS, different approaches to the assessment of safety culture, and the relationship between elements/processes of an SMS and a strong safety culture. A semistructured interview protocol was used. The researcher interviewed five safety professionals at U.S. collegiate flight training institutions of various sizes. Overall, the general consensus among the participants was that an SMS works best if it is implemented over time. A confidential hazard reporting system and the use of the five-step Safety Risk Management (SRM) process were viewed as important aspects to help build a strong safety culture. Other elements and processes were identified as having a strong relationship to safety culture as well. The participants revealed when their institution experienced a cultural change during SMS development. The study also provides recommendations for establishing a SMS

Examining the Relationship Between Safety Management System Implementation and Safety Culture in Collegiate Flight Schools

Safety management systems (SMS) are becoming the industry standard for safety management throughout the aviation industry. As the Federal Aviation Administration continues to mandate SMS for different segments, the assessment of an organization’s safety culture becomes more important. An SMS can facilitate the development of a strong aviation safety culture. This study describes how safety culture and SMS are integrated. The purpose of this study was to examine the relationship between an organization’s safety culture and SMS implementation in collegiate flight schools. The research study was designed to determine (a) the relationship between SMS implementation and safety culture, (b) the relationship between safety promotion and safety culture, and (c) the relationship between management commitment and safety culture. The study population consisted of 453 students and employees from 13 collegiate flight schools. Data were gathered through an online survey at collegiate flight schools within the University Aviation Association utilizing the Collegiate Aviation Program Safety Culture Survey (CAPSCUS) to measure the safety culture at those collegiate flight schools. The results indicated that a relationship existed between SMS implementation and safety culture, safety promotion and safety culture, management commitment and safety culture. The relationship for all three was more prominent within the Formal Safety Program major scale of the CAPSCUS

Zappa-Sz\'ep product groupoids and C*-blends

We study the external and internal Zappa-Sz\'ep product of topological groupoids. We show that under natural continuity assumptions the Zappa-Sz\'ep product groupoid is \'etale if and only if the individual groupoids are \'etale. In our main result we show that the C*-algebra of a locally compact Hausdorff \'etale Zappa-Sz\'ep product groupoid is a C*-blend, in the sense of Exel, of the individual groupoid C*-algebras. We finish with some examples, including groupoids built from *-commuting endomorphisms, and skew product groupoids.Comment: Updated to agree with published versio

Perspectives and Researcher Experiences of Undergraduate Research

Extracurricular undergraduate research seems to improve student success in academic programs, but little research has been conducted in aviation settings to support this phenomenon. This study aims to address the gap in the body of research by investigating the experiences of aviation students who have participated in extracurricular research at the undergraduate level. This case study, conducted within a large aviation program at a mid-sized Midwestern university, qualitatively examines the perceptions and experiences of these students

Epigenetic aging signatures in mice livers are slowed by dwarfism, calorie restriction and rapamycin treatment

Background: Global but predictable changes impact the DNA methylome as we age, acting as a type of molecular clock. This clock can be hastened by conditions that decrease lifespan, raising the question of whether it can also be slowed, for example, by conditions that increase lifespan. Mice are particularly appealing organisms for studies of mammalian aging; however, epigenetic clocks have thus far been formulated only in humans. Results: We first examined whether mice and humans experience similar patterns of change in the methylome with age. We found moderate conservation of CpG sites for which methylation is altered with age, with both species showing an increase in methylome disorder during aging. Based on this analysis, we formulated an epigenetic-aging model in mice using the liver methylomes of 107 mice from 0.2 to 26.0 months old. To examine whether epigenetic aging signatures are slowed by longevity-promoting interventions, we analyzed 28 additional methylomes from mice subjected to lifespan-extending conditions, including Prop1df/df dwarfism, calorie restriction or dietary rapamycin. We found that mice treated with these lifespan-extending interventions were significantly younger in epigenetic age than their untreated, wild-type age-matched controls. Conclusions: This study shows that lifespan-extending conditions can slow molecular changes associated with an epigenetic clock in mice livers

Criminal Justice and Suicide Outcomes with Indiana's Risk-Based Gun Seizure Law

This article examines the application and effectiveness of a 2006 Indiana law designed to prevent gun violence by authorizing police officers to separate firearms from persons who present imminent or future risk of injury to self or others, or display a propensity for violent or emotionally unstable conduct. A court hearing is held to determine ongoing risk in these cases; a judge decides whether to return the seized firearms or retain them for up to five years. The study examines the frequency of criminal arrest as well as suicide outcomes for 395 gun-removal actions in Indiana. Fourteen individuals (3.5%) died from suicide, seven (1.8%) using a firearm. The study population's annualized suicide rate was about 31 times higher than that of the general adult population in Indiana, demonstrating that the law is being applied to a population genuinely at high risk. By extrapolating information on the case fatality rate for different methods of suicide, we calculated that one life was saved for every 10 gun-removal actions, similar to results of a previous study in Connecticut. Perspectives from key stakeholders are also presented along with implications for gun policy reform and implementation

Evolution of Oviposition Techniques in Stick and Leaf Insects (Phasmatodea)

Stick and leaf insects (Phasmatodea) are large, tropical, predominantly nocturnal herbivores, which exhibit extreme masquerade crypsis, whereby they morphologically and behaviorally resemble twigs, bark, lichen, moss, and leaves. Females employ a wide range of egg-laying techniques, largely corresponding to their ecological niche, including dropping or flicking eggs to the forest floor, gluing eggs to plant substrate, skewering eggs through leaves, ovipositing directly into the soil, or even producing a complex ootheca. Phasmids are the only insects with highly species-specific egg morphology across the entire order, with specific egg forms that correspond to oviposition technique. We investigate the temporal, biogeographic, and phylogenetic pattern of evolution of egg-laying strategies in Phasmatodea. Our results unequivocally demonstrate that the ancestral oviposition strategy for female stick and leaf insects is to remain in the foliage and drop or flick eggs to the ground, a strategy that maintains their masquerade. Other major key innovations in the evolution of Phasmatodea include the (1) hardening of the egg capsule in Euphasmatodea; (2) the repeated evolution of capitulate eggs (which induce ant-mediated dispersal, or myrmecochory); (3) adapting to a ground or bark dwelling microhabitat with a corresponding shift in adult and egg phenotype and egg deposition directly into the soil; and (4) adhesion of eggs in a clade of Necrosciinae that led to subsequent diversification in oviposition modes and egg types. We infer at minimum 16 independent origins of a burying/inserting eggs into soil/crevices oviposition strategy, 7 origins of gluing eggs to substrate, and a single origin each of skewering eggs through leaves and producing an ootheca. We additionally discuss the systematic implications of our phylogenetic results. Aschiphasmatinae is strongly supported as the earliest diverging extant lineage of Euphasmatodea. Phylliinae and Diapheromerinae are both relatively early diverging euphasmatodean taxa. We formally transfer Otocrania from Cladomorphinae to Diapheromerinae and recognize only two tribes within Diapheromerinae: Diapheromerini sensu nov. and Oreophoetini sensu nov. We formally recognize the clade comprising Necrosciinae and Lonchodinae as Lonchodidae stat. rev. sensu nov

Resilience Assessment : International Best Practice Principles

PURPOSE This document sets out international best-practice principles for resilience assessment being undertaken within an impact assessment (IA) of some project, plan, programme, or policy (in this context, its function may be different to that of a self-standing resilience assessment). Resilience assessment can contribute to impact assessment by defining specific disturbances that can lead to failure of natural, social, and engineered systems. The disturbance can be caused either by the proposed action, factors beyond the influence of proposed action, or combination of both. The impact assessment can consider all these factors within one coherent framework. It can identify synergies and knock-on effects that can cause potential system failures, and advise on interventions that avoid failures in the critical functions of the system BACKGROUND Resilience assessment evaluates the structure and function of a system of focus (hereafter ‘focal system’) and, in the context of an impact assessment, focuses on the effects of the proposed action on the resilience of that focal system. The focal system can include: socio-ecological, biophysical, engineering, technological, or other components. Resilience assessment should ideally examine the consequences of the proposed action in combination with internal or external factors that may collectively influence the resilience of the focal system (e.g., biophysical system change caused by global warming on engineered structures)

Actin-myosin–based contraction is responsible for apoptotic nuclear disintegration

Membrane blebbing during the apoptotic execution phase results from caspase-mediated cleavage and activation of ROCK I. Here, we show that ROCK activity, myosin light chain (MLC) phosphorylation, MLC ATPase activity, and an intact actin cytoskeleton, but not microtubular cytoskeleton, are required for disruption of nuclear integrity during apoptosis. Inhibition of ROCK or MLC ATPase activity, which protect apoptotic nuclear integrity, does not affect caspase-mediated degradation of nuclear proteins such as lamins A, B1, or C. The conditional activation of ROCK I was sufficient to tear apart nuclei in lamin A/C null fibroblasts, but not in wild-type fibroblasts. Thus, apoptotic nuclear disintegration requires actin-myosin contractile force and lamin proteolysis, making apoptosis analogous to, but distinct from, mitosis where nuclear disintegration results from microtubule-based forces and from lamin phosphorylation and depolymerization