Los caldos leoneses

En número dedicado a: León: El Bierzo y Vallegord

Repercusión del Brexit en las empresas del Ibex 35

Análisis de la repercusión que ha tenido el Brexit desde la celebración del referéndum en las empresas del Ibex 35. Para ello se ha analizado el conjunto del Ibex 35 desde los días previos al referéndum hasta un año después. Del mismo modo, se ha realizado un análisis de los diferentes sectores empresariales dentro del Ibex 35 y de cada una de las empresas con mayor exposición a los problemas derivados del Brexit.Grado en Administración y Dirección de Empresa

Generación de una colección de referencia del barcode genético de Tenebrionidae (Coleoptera) en las Islas Canarias

El objetivo principal de este Trabajo de Fin de Grado es la creación de una base de datos de secuencias de ADN (fragmento barcode) para el grupo Tenebrionidae (Coleoptera) donde se incluirán las diferentes especies con las que se ha trabajado, para ello se utilizaron repositorios online de secuencias de barcode de ADN. Se empleó la colección de invertebrados identificados y conservados en alcohol del Departamento de Zoología de la Universidad de La Laguna, inicialmente conformada por 293 ejemplares de la familia Tenebrionidae. De todos ellos, se seleccionaron 95 individuos correspondientes a 14 géneros y se obtuvo la secuencia de ADN para el gen citocromo oxidasa subunidad 1 (COI) mediante PCR, la cual fue amplificada y posteriormente se secuenció. Una vez obtenida su secuencia se comparó con las secuencias de los repositorios online de las bases de datos BOLD y GenBank. A nivel de familia, en ambas bases de datos, la coincidencia era del 100%. A nivel de género y especie, la coincidencia oscilaba entre 90-95%. Hemos obtenido 70 nuevas secuencias en BOLD y 68 en GenBank. Este resultado se explica puesto que no hay datos representativos de las Islas Canarias, como consecuencia de que estudios anteriores no se secuencia la región COI del barcode, sino otro fragmento (Citocromo b). Por tanto a la hora de buscar en las bases de datos de BOLD y GenBank las identificaciones moleculares no coinciden con las taxonómicas.The main objective of this Final Degree Project is to develop a database where the different species which we have worked with will be included. We will compare our sequences with online repositories of DNA barcode sequences. A collection of identified and alcohol - preserved invertebrates from the Departamento de Zoología de la Universidad de la Laguna was used, which initially was made up of 293 specimens from the Tenebrionidae family. From all of them, 95 specimens of 14 different genera were selected to obtain the DNA sequence for the cytochrome oxidase subunit 1 (COI) by PCR. A fragment of this mitochondrial gene was amplified and subsequently sequenced. The obtained sequences were compared with other sequences from online repositories in BOLD and GenBank databases. At the family clevel, there was a 100% of coincidence between the samples in both databases, although at genus and species level the coincidence between the samples ranged from t 90 to 95% of similarity. In this Final Degree Project, we obtained 70 new sequences not present in BOLD database, and 68 new sequences in GenBank database. This results can be explained because of the lack of representative data of this coleoptera Family in the Canary Islands, as a consequence of the use of the Cytochrome b fragment of the barcode instead of the COI region. Thus, it may explain why the molecular identifications do not match with the taxonomic ones when looking up in BOLD and GenBank database

Traducción Automática a Lectura Fácil de Estructuras Morfológicas en Español

The Easy-to-Read (E2R) Methodology was created to improve the daily life of people with cognitive disabilities. This methodology aims to present clear and easily understood documents by means of providing a set of guidelines related to the writing and layout of texts. Some of these guidelines focus on morphological aspects that may cause difficulties in reading comprehension. Examples of those guidelines are: (a) to avoid the use of adverbs ending in -mente (-ly in English), and (b) to avoid the use of superlative forms. Currently, the E2R guidelines are applied manually to create easy-to-read text materials. To help in such a manual process, our research line is focused on applying the E2R Methodology in an automatic fashion to improve cognitive accessibility. Specifically, in this paper we present (a) the inclusive design approach for the development of E2R translation methods for avoiding both adverbs ending in -mente and superlative forms, and (b) the initial rule-based methods for adapting those linguistic structures into an Easy-to-Read form.La Metodología de Lectura Fácil (LF) tiene como objetivo presentar documentos claros y de fácil comprensión para personas con discapacidad cognitiva. Para ello, incluye una serie de pautas relacionadas con la redacción y disposición de textos. Algunas de estas pautas se centran en aspectos morfológicos que pueden causar dificultades en la comprensión lectora, como (a) evitar el uso de adverbios en -mente y (b) evitar el uso de formas superlativas. Las pautas de LF se aplican manualmente, por lo que, para ayudar en este proceso, nuestra línea de investigación se centra en aplicar la Metodología de LF de forma automática con el fin de mejorar la accesibilidad cognitiva en textos en español. Así, en este trabajo presentamos (a) un enfoque de diseño inclusivo en el desarrollo de métodos de adaptación de LF para evitar adverbios en -mente y superlativos, y (b) dos métodos iniciales basados en reglas para adaptar dichas estructuras lingüísticas a versiones en lectura fácil.This research has been financed by Asociación Inserta Innovación (part of Grupo Social Once) through Prosvasi Ciencia y Tecnología Para La Inclusión, A.I.E., within the project ACCESSJOBS

Training in personal defense techniques and its influence on the stress threshold of students

Training in self-defense techniques is carried out regularly in both civil and military contexts. Self-defense techniques are put into practice in dangerous situations such us a threat or a physical attack, which can generate great stress on the individual. When carrying out this study, we wanted to analyze the influence that training in self-defense techniques has on the stress experienced by students in a dangerous situation or while being attacked. For this reason, I have compared the measure of stress experienced by 14 students during their performance, facing situations of physical threat that they perform in simulated self-defense practices, which are carried out in this training. The student’s stress was measured with the Determination Test (DT) of the Vienna Test System. These defense practices against simulated attack situations take place at two different moments within the training course, one at the beginning and another once the training course has finished; therefore, the students have completely learned the defense techniques. I carried out the first measure of stress in situations of physical threat, in the simulation at the beginning of the training course, when the students had not yet learned any self-defense techniques. The second measurement was performed 21 days later, when the students had received self-defense training. This came during the simulation of situations of physical threat that is developed once the teaching of these techniques has finished and occurs at the end of the training course. The results show that the stress tolerance threshold increases with training. The results obtained in the variables measured pre and post show a decrease in the "median reaction time to the stimuli" and an increase in the variables "number of stimuli answered" and "correct reactions". This demonstrates that these subjects achieved a stress tolerance threshold in stressful situations with the highest physical threat, which was at the end of this formation. Therefore, there is an important degree of difference in the stress resistance of the subjects before the simulation of the first day of training, and that of the last day once they had already learned the self-defense techniques.   These findings could contribute to highlighting the usefulness of this type of training both in military units and in civilian entities, not only to improve technical knowledge of self-defense but also to promote a more adaptive stress response in this type of situation

Portable colorimetric enzymatic disposable biosensor for histamine and simultaneous histamine/tyramine determination using a smartphone

Tyramine oxidase (TAO), peroxidase (HRP), and Amplex Red (AR) have been immobilized on cellulose to obtain disposable biosensors for the determination of histamine. During the enzymatic reaction, AR is oxidized and a pink spot is obtained. Using a smartphone and measuring the G (green) color coordinate, histamine can be determined in the presence of other biogenic amines (putrescine and cadaverine) in concentrations ranging from 2·10−5 M to 5·10−4 M with a 7.5·10−6 M limit of detection (LoD). Despite tyramine interference, experimental conditions are provided which allow rapid and simple histamine and simultaneous histamine/tyramine (semi)quantitative determination in mixtures. Finally, tyramine and histamine were determined in a tuna extract with good results (compared to the reference HPLC–MS method). The methodology can also be applied in solution allowing histamine (and simultaneous histamine/tyramine) determination with a lower LoD (1.8·10−7 M) and a similar selectivity

Four-Legs D-STATCOM for Current Balancing in Low-Voltage Distribution Grids

The fast deployment of distributed energy resources (DERs) is creating a series of challenges that should be addressed in the coming years. In particular, distribution grids are playing an increasingly important role in the electricity system. Moreover, the three-phase four-wire structure of this network contribute to the appearance of imbalances and a series of problems derived from them. In this context, distribution system operators (DSOs), as the main responsible for the distribution grid, must ensure the quality of supply to consumers. This paper takes advantage of a four-legs D-STATCOM to remove current imbalances in low-voltage power lines. A 35-kVA prototype has been developed and installed in an urban distribution grid. The effect of the D-STATCOM has been analyzed during its first month of operation, studying and measuring the advantages of providing DERs the ability to perform active balancing to the utility grid. The results show a reduction in current imbalances from 21 % to 0 % and neutral current from 10.3 A to 0.4 A. In addition, a 13 % decrease in cable losses has been estimated and a slight improvement in voltage unbalance factor can be noted

Alternativas de conciliación e innovaciones en la oferta deportiva dirigidas a disminuir las barreras para la práctica de actividad física de las personas adultas en España: diferencias de género

En la actualidad, debido a los cambios demográficos acaecidos en las últimas décadas, las personas adultas constituyen aproximadamente la mitad de la población española. En España, aunque se han reducido las desigualdades en el acceso a la práctica deportiva, las mujeres (31%) practican menos deporte que los hombres (49.1%) y las personas adultas continúan siendo uno de los grupos de edad que, junto con los mayores, menos deporte practica (36%)(García y Llopis, 2011). Esta situación impide a un importante segmento de población acceder a los beneficios sociales y de salud que se obtienen con la práctica de actividades físico-deportivas, además de poder afectar negativamente a la práctica deportiva de las futuras generaciones y al gasto sanitario español

Plasmonic Copper Sulfide Nanoparticles Enable Dark Contrast in Optical Coherence Tomography

This is the peer reviewed version of the following article: Marin, R., Lifante, J., Besteiro, L. V., Wang, Z., Govorov, A. O., Rivero, F., ... & Jaque, D. (2020). Plasmonic Copper Sulfide Nanoparticles Enable Dark Contrast in Optical Coherence Tomography. Advanced Healthcare Materials 2020 9.5 (2020): 1901627, which has been published in final form at https://onlinelibrary.wiley.com/doi/full/10.1002/adhm.201901627. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived VersionsOptical coherence tomography (OCT) is an imaging technique affording noninvasive optical biopsies. Like for other imaging techniques, the use of dedicated contrast agents helps better discerning biological features of interest during the clinical practice. Although bright OCT contrast agents have been developed, no dark counterpart has been proposed yet. Herein, plasmonic copper sulfide nanoparticles as the first OCT dark contrast agents working in the second optical transparency window are reported. These nanoparticles virtually possess no light scattering capabilities at the OCT working wavelength (≈1300 nm); thus, they exclusively absorb the probing light, which in turn results in dark contrast. The small size of the nanoparticles and the absence of apparent cytotoxicity support the amenability of this system to biomedical applications. Importantly, in the pursuit of systems apt to yield OCT dark contrast, a library of copper sulfide nanoparticles featuring plasmonic resonances spanning the three optical transparency windows is prepared, thus highlighting the versatility and potential of these systems in light-controlled biomedical applicationsThis project was partially funded by the European Commission through the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie Grant agreement No. 797945 “LANTERNS”. This work was partially supported by the Ministerio de Economía y Competitividad de España (MAT2016-75362-C3-1-R) and (MAT2017-83111R), by the Instituto de Salud Carlos III (PI16/00812), by the Comunidad Autónoma de Madrid (B2017/BMD-3867RENIMCM), and co-financed by the European Structural and investment fund. Additional funding was provided by the European Commission Horizon 2020 project NanoTBTech. L.V.B was supported by the Institute of Fundamental and Frontier Sciences, University of Electronic Science and Technology of China and China Postdoctoral Science Foundation (2017M622992 and 2019T120820). Z.W. was supported by the National Basic Research Program of China (Project 2013CB933301) and the National Natural Science Foundation of China (Project 51272038). A.G. was funded via the 1000-talent Award of Sichuan and by the Volkswagen Foundation. Prof. Jorge Rubio-Retama is gratefully acknowledged for granting access to the dynamic light scattering instrument and for the fruitful discussio

Control of COVID-19 Outbreak for Preventing Collapse of Healthcare Capacity based on Social Distancing, Confinement and Testing-Quarantining

This work is a contribution to the call to TheIFAC-CSS Corona Control Community Project in February2020. Scientific evidence to the effectiveness of the three mainnon-pharmacological tools to mitigate a pandemic is given. Acontrol system to control the Covid-19 outbreak caused by theSars-CoV2 virus, called Coronavirus, is proposed, forpreventing collapse of the health systems and saturation ofIntensive Therapy Units (ITUs) capacity. The proposed systemis based on the three existing non-pharmacological tools for themitigation of epidemics and pandemics: social distancing,confinement and testing with isolation of a population in whichthere is community circulation of the virus. Both in the analysisand in the design of the control system, the mathematicalmodel SEIRD (Susceptible - Exposed - Infected - Recovered -Deceased) is used, which describes the dynamics of a pandemic,adjusted in this work to the behavior in space and time of theSars-CoV2. In this work the incidence and impact of testingwith isolation (or testing-quarantining) is incorporated in themodel. The proposed control system uses, as a feedback signal,the demanded quantity of critical beds and ITUs, which iscompared with the available beds capacity to generate theerror signal as input to a PID controller. As control actions,five Phases of Social Distancing and Confinement (SD&C) areproposed, which must be applied by the public authority. Thecontrol system thus generates a SD&C decision sequence orpolicy, which can be applied once a week or every fortnight.Simulation results showing the practical feasibility and goodperformance of the proposed control system are given,preventing collapse of Healthcare Capacity based on SocialDistancing, Confinement and Testing-quarantining as controlactions.Fil: Patiño, Héctor Daniel. Universidad Nacional de San Juan. Facultad de Ingeniería. Instituto de Automática; ArgentinaFil: Tosetti Sanz, Santiago Ramon. Universidad Nacional de San Juan. Facultad de Ingeniería. Instituto de Automática; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan; ArgentinaFil: Pucheta, Julián Antonio. Universidad Nacional de Córdoba. Facultad de Cs.exactas Físicas y Naturales. Departamento de Electronica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan; ArgentinaFil: Rodriguez Rivero, Cristian Maximiliano. University of Amsterdam; Países Bajos2020 IEEE Congreso Bienal de Argentina (ARGENCON)ChacoArgentinaInstitute of Electrical and Electronics Engineer