Mindfulness and Executive Functions : Making the Case for Elementary School Practice

This study explores the use of mindfulness school-based intervention program in an elementary school. Mindfulness training is an accepted and effective didactic approach to improve the executive functions (EFs) of elementary school students. This study aimed to evaluate the effects of the Mind Yeti program on the executive functions of elementary school students. A diverse sample of third, fourth, and fifth grade elementary school students (n = 177) participated in their natural classroom setting, with six sessions per week for six weeks. Students self-reported their EFs on the Executive Function Student Questionnaire (EFSQ) pre- and posttest. Paired-sample t-tests indicated that students significantly improved on the three of the six EFs examined. Additionally, students in fifth grade responded better to Mind Yeti than students in third grade. Results were consistent with the hypothesis, suggesting that Mind Yeti is an appropriate and effective intervention for improving the EFs of students

The Epidemiology of post-traumatic seizures following moderate to severe traumatic brain injury

Though death rates due to traumatic brain injury (TBI) are decreasing in the United Statues, TBI remains a significant public health problem. Individuals who survive moderate and severe TBI become at risk of developing secondary complications, including post-traumatic seizures (PTS). PTS are well-recognized sequelae of TBI. Despite previous research, there remains a high degree of variability in who will develop PTS and no approved prophylactic medications to prevent late PTS exist. Late PTS is associated with significant morbidity and worse outcomes following TBI. Therefore, it is of public health importance to understand the characteristics of individuals with PTS, identify factors to improve prognostication, and explore novel risk factors to support a personalized medicine approach. Using the Traumatic Brain Injury Model Systems, we examined the incidence of immediate (7 days post-injury) PTS. Incidence of new onset seizures was highest immediately (8.9%) and one-year (9.2%) post-injury. Late PTS prevalence surpassed 20% at five-years post-injury. Incidence was stratified by potential risk factors and relative risk calculated. Individuals with immediate but not early seizures had a significantly greater incidence of late PTS compared to individuals not seizing during acute hospitalization. We then developed and internally validated prognostic models for PTS during acute hospitalization, at one-year, and two-years post-TBI. We identified multiple variables, including novel factors such as pre-injury mental health conditions, predictive of PTS. Year one and two models showed fair-to-good ability to discriminate PTS, supporting the idea that more accurate prognostication of late PTS can be accomplished. Lastly, we examined genetic variation in neuronal glutamate transporter genes as risk factors for PTS. We identified genetic variants significantly associated with increased PTS risk, after controlling for known risk factors. The relative effect size of the genetic markers suggests these variants may be significant predictors of PTS and may improve prognostic model reliability and validity. Classifying subpopulations at high-risk for PTS could facilitate research regarding the effectiveness of tiered prophylaxis and novel pharmacological interventions, improving prevention and treatment. Together, findings from the current work may affect future research and programmatic decisions, positively impacting those at risk for PTS

Simulation and observations of stratospheric aerosols from the 2009 Sarychev volcanic eruption

We used a general circulation model of Earth’s climate to conduct simulations of the 12-16 June 2009 eruption of Sarychev volcano (48.1°N, 153.2°E). The model simulates the formation and transport of the stratospheric sulfate aerosol cloud from the eruption and the resulting climate response. We compared optical depth results from these simulations with limb scatter measurements from the Optical Spectrograph and InfraRed Imaging System (OSIRIS), in situ measurements from balloon-borne instruments lofted from Laramie, Wyoming (41.3°N, 105.7°W), and five lidar stations located throughout the Northern Hemisphere. The aerosol cloud covered most of the Northern Hemisphere, extending slightly into the tropics, with peak backscatter measured between 12 and 16 km in altitude. Aerosol concentrations returned to near background levels by Spring, 2010. After accounting for expected sources of discrepancy between each of the data sources, the magnitudes and spatial distributions of aerosol optical depth due to the eruption largely agree. In conducting the simulations, we likely overestimated both particle size and the amount of SO2 injected into the stratosphere, resulting in modeled optical depth values that were a factor of 2-4 too high. Model results of optical depth due to the eruption show a peak too late in high latitudes and too early in low latitudes, suggesting a problem with stratospheric circulation in the model. The model also shows a higher annual decay rate in optical depth than is observed, showing an inaccuracy in seasonal deposition rates. The modeled deposition rate of sulfate aerosols from the Sarychev eruption is higher than the rate calculated for aerosols from the 1991 eruption of Mt. Pinatubo

Social Impact Assessment in Europe:A Study of Social Impacts in Three Danish Cases

Social impact assessment (SIA) is applied worldwide to assess social impacts of plans and projects. In Europe, directives on environmental assessment (EA) require attention to social impacts, however, there is a need to investigate the implementation in practise. To this end, we study three Danish cases, which are characterised by debates and conflicts on social issues. Analysis of the EA statements shows inclusion of a broad range of social impacts. However, the EAs do not fully match the concerns of the public, and social impacts are not always analysed in depth, mitigation measures are not suggested or are postponed and the geographical distribution of impacts assessed is biased towards including negative local impacts. We discuss the scope and handling of social impacts, and possible implications. Based on this, we conclude with the view that EA might do the job of handling social impacts in Europe, if practise is improved. </jats:p

Arbeitsvermögen und Arbeitslosigkeit: empirische und theoretische Ergebnisse der SGB-II-Evaluation

Mit der Einführung des SGB II rückt die Aktivierung von Leistungsempfängern ins Zentrum der Aufgabenbereiche "arbeitsmarktnaher sozialer Dienstleistungen". Hilfebedürftigkeit wird dabei zum komplexen Phänomen, das über das theoretische Konzept des Arbeitsvermögens im Entstehungskontext untersucht wird. Es geht um die Bedingungen, unter denen Hilfebedürftigkeit im Sinne des SGB II entsteht, sich gegebenenfalls verstetigt und überwunden werden kann. Der Ansatz des Arbeitsvermögens erlaubt es, in die Forschung all diejenigen Aspekte einzubeziehen, die sich formalen Formen der Zertifizierung entziehen und somit jenseits klassischer Marktgängigkeit zu verorten sind

Varicella zoster virus glycoprotein C increases chemokine-mediated leukocyte migration

Varicella zoster virus (VZV) is a highly prevalent human pathogen that establishes latency in neurons of the peripheral nervous system. Primary infection causes varicella whereas reactivation results in zoster, which is often followed by chronic pain in adults. Following infection of epithelial cells in the respiratory tract, VZV spreads within the host by hijacking leukocytes, including T cells, in the tonsils and other regional lymph nodes, and modifying their activity. In spite of its importance in pathogenesis, the mechanism of dissemination remains poorly understood. Here we addressed the influence of VZV on leukocyte migration and found that the purified recombinant soluble ectodomain of VZV glycoprotein C (rSgC) binds chemokines with high affinity. Functional experiments show that VZV rSgC potentiates chemokine activity, enhancing the migration of monocyte and T cell lines and, most importantly, human tonsillar leukocytes at low chemokine concentrations. Binding and potentiation of chemokine activity occurs through the C-terminal part of gC ectodomain, containing predicted immunoglobulin-like domains. The mechanism of action of VZV rSgC requires interaction with the chemokine and signalling through the chemokine receptor. Finally, we show that VZV viral particles enhance chemokine-dependent T cell migration and that gC is partially required for this activity. We propose that VZV gC activity facilitates the recruitment and subsequent infection of leukocytes and thereby enhances VZV systemic dissemination in humans

3-D Magnetotelluric Image of Offshore Magmatism at the Walvis Ridge and Rift Basin

Highlights • We report on marine 3D Magnetotelluric study on Walvis Ridge • Derived 3D electrical resistivity model shows a large scale resistive zone, which we link to crustal extension due to local uplift. It might indicate the location where the hot-spot impinged on the crust prior to rifting • Smaller scale resistive region is attributed to magma ascent during rifting • Rift basin is identified by low resistivity region The Namibian continental margin marks the starting point of the Tristan da Cunha hotspot trail, the Walvis Ridge. This section of the volcanic southwestern African margin is therefore ideal to study the interaction of hotspot volcanism and rifting, which occurred in the late Jurassic/early Cretaceous. Offshore magnetotelluric data image electromagnetically the landfall of Walvis Ridge. Two large-scale high resistivity anomalies in the 3-D resistivity model indicate old magmatic intrusions related to hot-spot volcanism and rifting. The large-scale resistivity anomalies correlate with seismically identified lower crustal high velocity anomalies attributed to magmatic underplating along 2-D offshore seismic profiles. One of the high resistivity anomalies (above 500 Ωm) has three arms of approximately 100 km width and 300 km to 400 km length at 120 degree angles in the lower crust. One of the arms stretches underneath Walvis Ridge. The shape is suggestive of crustal extension due to local uplift. It might indicate the location where the hot-spot impinged on the crust prior to rifting. A second, smaller anomaly of 50 km width underneath the continent ocean boundary may be attributed to magma ascent during rifting. We attribute a low resistivity anomaly east of the continent ocean boundary and south of Walvis Ridge to the presence of a rift basin that formed prior to the rifting