64 research outputs found

    A study of thirty-seven mentally retarded delinquent boys referred by the Juvenile Court to attend the Citizenship Training Department

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    Thesis (M.S.)--Boston University, 1947. This item was digitized by the Internet Archive

    Warranty Deed of F LeCocq Jr. and Rhoda LeCocq, November 1, 1904

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    Warranty deed between Frank LeCocq Jr and Rhoda LeCocq, and F LeCocq Sr. relating to a parcel of land in the County of Douglas and State of South Dakota.https://nwcommons.nwciowa.edu/franklecocqjr/1016/thumbnail.jp

    Warranty Deed of F LeCocq Jr. and Rhoda LeCocq, October 22, 1901

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    Warranty Deed for $500 paid by F LeCocq Sr. to F LeCocq Jr. and Rhoda on October 22, 1901.https://nwcommons.nwciowa.edu/franklecocqjr/1011/thumbnail.jp

    Warranty Deed of F LeCocq Jr. and Rhoda LeCocq, October 22, 1901

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    Warranty deed in the amount of $1500 paid by F LeCocq Sr. to F LeCocq Jr. and wife Rhoda on October 22nd, 1901.https://nwcommons.nwciowa.edu/franklecocqjr/1012/thumbnail.jp

    Quit Claim Deed of F LeCocq Jr. and Rhoda, March 5, 1904

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    Quit Claim Deed detailing the replanning of a deed dated October 15, 1902 that was lost.https://nwcommons.nwciowa.edu/franklecocqjr/1014/thumbnail.jp

    First Mortgage Note of F LeCocq Jr. and Rhoda LeCocq, October 15, 1901

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    First Mortgage Note of F LeCocq Jr. and wife Rhoda, of the amount of $600, signed Oct 15, 1901 and due on Oct 15, 1906.https://nwcommons.nwciowa.edu/franklecocqjr/1010/thumbnail.jp

    Evaluation of the Airdrie Sheriff Youth Court Pilot - Research Findings

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    A pilot Youth Court was introduced at Airdrie Sheriff Court in June 2004. It is targeted on alleged offenders aged 16 and 17 (and appropriate 15 year olds) who are resident in areas of North Lanarkshire and are appearing summarily before Airdrie Sheriff Court. The main aim of the Youth Court is to reduce the frequency and seriousness of offending by 16 and 17 year olds through targeted and prompt disposals with judicial supervision and continuing social work involvement

    Evaluation of the Airdrie and Hamilton Youth Court Pilots - Research findings

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    Pilot Youth Courts were introduced at Hamilton Sheriff Court in June 2003 and at Airdrie Sheriff Court in June 2004. They are targeted at alleged offenders aged 16 and 17 (and appropriate 15 year olds) who are resident in areas of North and South Lanarkshire and are appearing summarily before the Sheriff Courts. Their main aims are to reduce the frequency and seriousness of offending through targeted and prompt disposals with judicial supervision and continuing social work involvement

    Structures of smooth muscle myosin and heavy meromyosin in the folded, shutdown state

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    Remodelling of the contractile apparatus within smooth muscle cells is an essential process that allows effective contractile activity over a wide range of cell lengths. The thick filaments may be redistributed via depolymerisation into inactive myosin monomers that have been detected in vitro, in which the long tail has a folded conformation. The structure of this folded molecule has been controversial. Using negative stain electron microscopy of individual folded molecules from turkey gizzard we show they are more compact than previously described, with heads and the three segments of the folded tail closely packed. Smooth muscle heavy meromyosin (HMM), which lacks two-thirds of the tail, closely resembles the equivalent parts of whole myosin. Image processing reveals a characteristic head region morphology for both HMM and myosin whose features are identifiable by comparison with less compact molecules. The two heads associate asymmetrically: the tip of one motor domain touches the base of the other, resembling the blocked and free heads of this HMM when it forms 2-D crystals on lipid. The tail of HMM lies between the heads, contacting the blocked motor domain, unlike in the 2-D crystal. The tail of the intact myosin is bent sharply and consistently at two positions close to residues 1175 and 1535. The first bend position correlates with a skip in the coiled coil sequence, the second does not. The first segment runs between the heads from the head-tail junction. Unexpectedly, the other segments associate only with the blocked head rather than both heads, such that the second bend lies at a specific position near the C-lobe of the blocked head regulatory light chain. Quantitative analysis of tail flexibility shows that the single coiled coil of HMM has an apparent Young’s modulus of about 0.5 GPa. The folded tail of the intact molecule is less flexible indicating interactions between the segments. The folded tail does not modify the compact head arrangement but stabilises it, indicating a structural mechanism for the very low ATPase activity of the folded molecule
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