La reforma electoral...un fraude

Después de diez arduos meses de debate y de intentos de alianza entre los partidos, se aprueba la reforma electoral, en donde los puntos debatidos fueron: el sistema electoral, la conformación de la Cámara de Diputados y la Asamblea de Representantes del Distrito Federal

La crisis de la deuda

El trabajo reseña la evolución del endeudamiento externo mexicano durante el periodo de 1970 a 1988, centrándose en las negociaciones efectuadas por el gobierno durante la década de la llamada "crisis de la deuda". En 1970 la deuda total a largo plazo, pública y privada, ascendía a 5.9 mdd, para 1975 ésta sumaba 18.4 mdd y para 1988 la deuda externa llegaba a rebasar los 100.0 mdd correspondiente a más de 80.0 mdd al sector publico y 7.0 mdd al sector privado

WMR Kinematic Control Using Underactuated Mechanisms for Goal Direction and Evasion

This work presents the mechanical design and the kinematic navigation control system for a tricycle-wheeled robot (one drive-steer and two lateral fixed passive) with two underactuated mechanisms: a global compass and local evasive compass. The proposed goal-reference mechanism is inspired by the ancient Chinese south-seeking chariot (c. 200–265 CE) used as a navigation compass. The passive lateral wheels transmit an absolute angle from its differential speeds to automatically steer the front wheel. An obstacle-evasive compass mechanism is commutated for steering control when detecting nearby obstacles. The absolute and local compass mechanisms commutate each other to control to the robot’s steering wheel to reach a goal while avoiding collisions. A kinematic control law is described in terms of the robot’s geometric constraints and is combined with a set of first-order partial derivatives that allows interaction between the global and local steering mechanisms. Animated simulations and numerical computations about the robot’s mechanisms and trajectories in multi-obstacle scenarios validate the proposed kinematic control system and its feasibility

Vineyard yeld estimation by VINBOT robot - preliminary results with the white variety Viosinho

Nowadays it is recognized that vineyard yield estimation can bring several benefits to all the vine and wine industry and, consequently, there is a strong demand for fast and reliable yield estimation methods. Recently a strong effort has been made on developing machine vision tools to automatically estimate vineyard yields evolving several research teams worldwide. In this paper we aim to present preliminary results obtained in the frame of an European research project (VINBOT: “Autonomous cloud-computing vineyard robot to optimise yield management and wine quality”) focus on yield estimation. A ground truth evaluation trial was set up in an experimental vineyard with the white variety Viosinho, trained on a vertical shoot positioning system and spur pruned. A sample of contiguous vines was labeled and submitted to a detailed assessment of vegetative and reproductive data to feed a viticulture data library. The vines were scanned during the ripening period of the 2015 season by the VINBOT sensor head composed with a set of sensors capable of capturing vineyard images and 3D data. Ground truth data was used to relate with images taken by the sensors and to test algorithms of image analysis. In this paper we present and discuss the relationships between actual and estimated yield computed using the surface occupied by the grape clusters in the images. Our preliminary results showed that, despite of a slight underestimation of the ground truth, caused mainly by cluster occlusion, when the canopy density allows visualization of most part of the clusters, the yield can be estimated by machine vision with a high fidelity. Further research is ongoing to test those devices and methodologies in other varieties and to improve the estimation accuracyinfo:eu-repo/semantics/publishedVersio

Bean production systems in Nicaragua: technology adoption in the face of climate adversity

We documented the bean production systems in Nicaragua, focusing on the adoption of improved bean varieties (IVs) under adverse climatic (rainfall) conditions and its economic effect on adopting households. Using data from a representative sample of 589 farmers (341 located in the dry corridor), we demonstrate statistical differences in the socioeconomic characteristics, farm characteristics, and bean management practices between IV adopters and non-adopters, and by region (i.e., dry vs. non-dry corridors). Farmers in the dry corridor obtained significantly lower yields compared to farmers in non-dry areas. Further, 30% of farmers in Nicaragua had adopted at least one improved bean variety in the seasons of interest, and 28.3% of the bean area was grown with IVs. Adopting an IV positively affected yields --farmers obtained 11% higher yields-- but had no statistically significant effect on profits. The results highlight the importance of growing improved bean varieties under adverse rainfall conditions, as farmers who adopted an IV in the dry corridor obtained 13.2% higher yields than non-adopters in the same region. We did not find statistical yield differences between IV adopters and non-adopters in non-dry regions

Infratentorial hygroma secondary to decompressive craniectomy after cerebellar infarction

We present a case of expansive CSF collection in the cerebellar convexity. The patient was a 74 years old lady who one month before had suffered a cerebellar infarct complicated with acute hydrocephalus. She had good evolution after decompressive craniectomy without shunting. Fifteen days after surgery, the patient started with new positional vertigo, nausea and vomiting and a wound CSF fistula that needed ventriculoperitoneal shunt (medium pressure) because conservative treatment failed. After shunting, the fistula closed, but the patient symptoms worsened. The MRI showed normal ventricular size with a cerebellar hygroma, extending to the posterior interhemispheric fissure. The collection had no blood signal and expanded during observation. A catheter was implanted in the collection and connected to the shunt. The patient became asymptomatic after surgery, and the hygromas had disappeared in control CT at one month. This case shows an infrequent problem of CSF circulation at posterior fossa that resulted in vertigo of central origin. A higroma-ventricle-peritoneal shunt solved the symptoms of the patient

Plasmodium falciparum Blood Stage Antimalarial Vaccines: An Analysis of Ongoing Clinical Trials and New Perspectives Related to Synthetic Vaccines

Plasmodium falciparum malaria is a disease causing high morbidity and mortality rates worldwide, mainly in sub-Saharan Africa. Candidates have been identified for vaccines targeting the parasite’s blood stage; this stage is important in the development of symptoms and clinical complications. However, no vaccine that can directly affect morbidity and mortality rates is currently available. This review analyzes the formulation, methodological design, and results of active clinical trials for merozoite-stage vaccines, regarding their safety profile, immunological response (phase Ia/Ib), and protective efficacy levels (phase II). Most vaccine candidates are in phase I trials and have had an acceptable safety profile. GMZ2 has made the greatest progress in clinical trials; its efficacy has been 14% in children aged less than 5 years in a phase IIb trial. Most of the available candidates that have shown strong immunogenicity and that have been tested for their protective efficacy have provided good results when challenged with a homologous parasite strain; however, their efficacy has dropped when they have been exposed to a heterologous strain. In view of these vaccines’ unpromising results, an alternative approach for selecting new candidates is needed; such line of work should be focused on how to increase an immune response induced against the highly conserved (i.e., common to all strains), functionally relevant, protein regions that the parasite uses to invade target cells. Despite binding regions tending to be conserved, they are usually poorly antigenic and/or immunogenic, being frequently discarded as vaccine candidates when the conventional immunological approach is followed. The Fundación Instituto de Inmunología de Colombia (FIDIC) has developed a logical and rational methodology based on including conserved high-activity binding peptides (cHABPs) from the main P. falciparum biologically functional proteins involved in red blood cell (RBC) invasion. Once appropriately modified (mHABPs), these minimal, subunit-based, chemically synthesized peptides can be used in a system covering the human immune system’s main genetic variables (the human leukocyte antigen HLA-DR isotype) inducing a suitable, immunogenic, and protective immune response in most of the world’s populations. © Copyright © 2019 Salamanca, Gómez, Camargo, Cuy-Chaparro, Molina-Franky, Reyes, Patarroyo and Patarroyo

Plasmodium falciparum pre-erythrocytic stage vaccine development

Worldwide strategies between 2010 and 2017 aimed at controlling malarial parasites (mainly Plasmodium falciparum) led to a reduction of just 18% regarding disease incidence rates. Many biologically-derived anti-malarial vaccine candidates have been developed to date; this has involved using many experimental animals, an immense amount of work and the investment of millions of dollars. This review provides an overview of the current state and the main results of clinical trials for sporozoite-targeting vaccines (i.e. the parasite stage infecting the liver) carried out by research groups in areas having variable malaria transmission rates. However, none has led to promising results regarding the effective control of the disease, thereby making it necessary to complement such efforts at finding/introducing new vaccine candidates by adopting a multi-epitope, multi-stage approach, based on minimal subunits of the main sporozoite proteins involved in the invasion of the liver. © 2020 The Author(s)

Pelvic floor dysfunction in Mexican women

Background: Pelvic floor dysfunction (PFD) is a term used to describe a variety of disorders that involve moderate to severe impairment of the pelvic floor muscles. Throughout their lives, up to 46% of women will present at least one form of PFD and may even have a combination of this pathology. These afflictions have a profound influence on women’s general well-being and quality of life, as well as being an immense economic burden for global health systems. Methods: This was a populational study which used surveys made in Google Forms of different questionnaires validated in Spanish [Urinary Incontinence Questionnaire (ICIQ), Female Sexual Function Index (IFSF), CPPQ Questionnaire for chronic pelvic pain, Wexner anal incontinence scale and quality of life] which were taken by women with access to social networks and who agreed to carry out an anonymous survey. Results: Seven hundred and twenty-one participants were evaluated, a total of 61.4% (443) responded positively to involuntary loss of urine, 35% had presented discomfort during sexual activity or lack of sexual interest, 14% had genital pain and 16% reported involuntary loss of feces or gas. Of all the patients that answered any of these questioners positively, only 33% had sought medical attention in the past. Conclusions: We concluded that in our population PFD is underdiagnosed. Our populations prevalence of urinary incontinence and pelvic pain is within the internationally described margins; anal incontinence is above international reports, and our population presented a lower prevalence of sexual dysfunction. With this new information we must impulse awareness to guide various preventive behaviors

Effectiveness of vaginal analgesic electrostimulation versus sacral electroacupuncture in chronic pelvic pain of myofascial origin

Background: Chronic pelvic pain (CPP) of myofascial origin is a condition that is difficult to control and with great repercussion on the quality of life for women who suffer from it. This study objective was to compare the effectiveness of two treatments for the management of this pathology; vaginal analgesic electrostimulation (VES) versus sacral electroacupuncture (EAS).Methods: Quasi-experimental comparative study of two treatments in patients with myofascial CPP. The sample was made up of women who presented this condition during the period 2016 to 2019. The main objective was to assess the effectiveness of the treatments in comparison in terms of the decrease in the VAS score, the secondary ones were: To know the effectiveness of the VES for pain chronic pelvic myofascial (MFPP), the effectiveness of EA for the same condition, complications of therapies, main urological dysfunctions and other chronic pelvic pain associated with myofascial CPP.Results: Thirteen thousand patient files were reviewed, of which 47 were diagnosed with myofascial CCP, with 38 patients eligible for our study. The VES was more effective than the EAS in decreasing the VAS in the twelfth session from 1.36 versus 2.62 p .001. Both therapies were effective for the management of myofascial DCP as they decreased the VAS score to more than 60% of the initial VAS. Vulvodynia (34%), mixed urinary incontinence (32%), and voiding symptoms (26%) were other pelvic floor dysfunctions that presented concomitantly to the MFPP.Conclusions: In patients with myofascial CPP, vaginal VES is better than AD for the treatment of this condition