296 research outputs found
The Role of Isostasy in the Evolution and Architecture of Fold and Thrust Belts
AbstractWarmer conditions prevalent in the hinterland of orogenic systems facilitate local ductile flow underneath the surface load, making Airy-like local isostasy more prevalent in these domains. In contrast, flexural isostasy better describes the regional response to surface loading of more rigid lithospheres. Here, we explore how the interaction between horizontal tectonic mass transfer and vertical isostatic mass transfer, through either elastic flexure or viscous flow, impacts the overall architecture of fold and thrust belts. We compare numerical models of fold and thrust belts under either an Airy-like ductile isostasy boundary condition or a flexural-like regional isostasy boundary condition. Our experiments suggest that when ductile flow is involved in accommodating isostatic adjustment, subsidence is rather local, larger, and results in narrower, less elevated fold-thrust belts with a complex internal architecture consisting of prominent steeply dipping faults. When isostatic subsidence is controlled by lithospheric flexure, the tilting of the basement on 10 s of km scale facilitates the outward propagation of fold-thrust belts. The internal architecture is simpler and involves prominent basement-parallel décollements. The outcome is wider fold and thrust belts with higher topographies. A change in lithospheric elastic thickness does not significantly affect fold-thrust belt structural styles. Our results are compared to natural examples from the Subandean zone
A deep subaqueous fan depositional model for the Palaeoarchaean (3.46 Ga) Marble Bar Cherts, Warrawoona Group, Western Australia
International audienceThe 3.46 Ga Marble Bar Chert Member of the East Pilbara Craton, Western Australia, is one of the earliest and best-preserved sedimentary successions on Earth. Here, we interpret the finely laminated thin-bedded cherts, mixed conglomeratic beds, chert breccia beds and chert folded beds of the Marble Bar Chert Member as the product of low-density turbidity currents, high-density turbidity currents, mass transport complexes and slumps, respectively. Integrated into a channel-levee depositional model, the Marble Bar Chert Member constitutes the oldest documented deep-sea fan on Earth, with thin-bedded cherts, breccia beds and slumps composing the outer levee facies tracts, and scours and conglomeratic beds representing the channel systems
Folie et lien social
Françoise Davoine, Jean-Max Gaudillère, maîtres de conférences L’acte de naissance des fantômes Notre recherche de cette année, outre les apports de la clinique psychanalytique de la folie, s’est largement appuyée sur l’œuvre de Robert Musil, et notamment sur L’homme sans qualités. En effet, ce texte magistral, sous l’ombre duquel le XXe siècle a tenté de s’écrire, présente les ingrédients mis en travail par la folie, avec l’exactitude qui caractérise toute la recherche de l’auteur autrichien..
Quantitative stratigraphic analysis in a source-to-sink numerical framework
The sedimentary architecture at continental margins reflects the interplay between the rate of change of accommodation creation (δA) and the rate of change of sediment supply (δS). Stratigraphic interpretation increasingly focuses on understanding the link between deposition patterns and changes in δA=δS, with an attempt to reconstruct the contributing factors. Here, we use the landscape modelling code pyBadlands to (1) investigate the development of stratigraphic sequences in a source-to-sink context; (2) assess the respective performance of two well-established stratigraphic interpretation techniques: the trajectory analysis method and the accommodation succession method; and (3) propose quantitative stratigraphic interpretations based on those two techniques. In contrast to most stratigraphic forward models (SFMs), pyBadlands provides self-consistent sediment supply to basin margins as it simulates erosion, sediment transport and deposition in a source-to-sink context. We present a generic case of landscape evolution that takes into account periodic sea level variations and passive margin thermal subsidence over 30 million years, under uniform rainfall. A set of post-processing tools are provided to analyse the predicted stratigraphic architecture. We first reconstruct the temporal evolution of the depositional cycles and identify key stratigraphic surfaces based on observations of stratal geometries and facies relationships, which we use for comparison to stratigraphic interpretations. We then apply both the trajectory analysis and the accommodation succession methods to manually map key stratigraphic surfaces and define sequence units on the final model output. Finally, we calculate shoreline and shelf-edge trajectories, the temporal evolution of changes in relative sea level (proxy for δA) and sedimentation rate (proxy for δS) at the shoreline, and automatically produce stratigraphic interpretations. Our results suggest that the analysis of the presented model is more robust with the accommodation succession method than with the trajectory analysis method. Stratigraphic analysis based on manually extracted shoreline and shelf-edge trajectory requires calibrations of time-dependent processes such as thermal subsidence or additional constraints from stratal terminations to obtain reliable interpretations. The 3-D stratigraphic analysis of the presented model reveals small lateral variations of sequence formations. Our work provides an efficient and flexible quantitative sequence stratigraphic framework to evaluate the main drivers (climate, sea level and tectonics) controlling sedimentary architectures and investigate their respective roles in sedimentary basin development. © Author(s) 2019.Acknowledgements. Xuesong Ding, Tristan Salles and Patrice Rey were supported by Australian Research Council grant IH130200012 (Basin GENESIS Hub), and Nicolas Flament was supported by Australian Research Council grant DE160101020. Ding acknowledges supports from the International Association for Mathematical Geosciences (IAMG) grant. This research was undertaken with the assistance of resources and services from the National Computational Infrastructure (NCI), which is supported by the Australian Government. We thank Zoltan Sylvester and Jack Neal for their constructive comments on this paper. We also thank Kyle Straub, Cornel Olariu and Jack Neal for their valuable comments on an earlier version of the manuscript. Australian Research Council (grant nos. IH130200012 and DE160101020)
Folie et lien social
Françoise Davoine, Jean-Max Gaudillère, maîtres de conférences L’acte de naissance des fantômes Notre recherche de cette année, outre les apports de la clinique psychanalytique de la folie, s’est largement appuyée sur l’œuvre de Robert Musil, et notamment sur L’homme sans qualités. En effet, ce texte magistral, sous l’ombre duquel le XXe siècle a tenté de s’écrire, présente les ingrédients mis en travail par la folie, avec l’exactitude qui caractérise toute la recherche de l’auteur autrichien..
Is the formula of Traub still up to date in antemortem blood glucose level estimation?
According to the hypothesis of Traub, also known as the ‘formula of Traub', postmortem values of glucose and lactate found in the cerebrospinal fluid or vitreous humor are considered indicators of antemortem blood glucose levels. However, because the lactate concentration increases in the vitreous and cerebrospinal fluid after death, some authors postulated that using the sum value to estimate antemortem blood glucose levels could lead to an overestimation of the cases of glucose metabolic disorders with fatal outcomes, such as diabetic ketoacidosis. The aim of our study, performed on 470 consecutive forensic cases, was to ascertain the advantages of the sum value to estimate antemortem blood glucose concentrations and, consequently, to rule out fatal diabetic ketoacidosis as the cause of death. Other biochemical parameters, such as blood 3-beta-hydroxybutyrate, acetoacetate, acetone, glycated haemoglobin and urine glucose levels, were also determined. In addition, postmortem native CT scan, autopsy, histology, neuropathology and toxicology were performed to confirm diabetic ketoacidosis as the cause of death. According to our results, the sum value does not add any further information for the estimation of antemortem blood glucose concentration. The vitreous glucose concentration appears to be the most reliable marker to estimate antemortem hyperglycaemia and, along with the determination of other biochemical markers (such as blood acetone and 3-beta-hydroxybutyrate, urine glucose and glycated haemoglobin), to confirm diabetic ketoacidosis as the cause of deat
Aquaculture system diversity and sustainable development : fish farms and their representation
Initiatives for the sustainable development of aquaculture have so far focused on the production of codes of conduct, of best management practices, of standards etc., most of which have been developed by international organisations, the industrial sector and non governmental organisations. They were, to a large extent, produced using a "top down" process and inspired by models from intensive industrial shrimp and sea fish farming (mainly salmon). However, most of global aquaculture production comes from small-and medium-sized farms, essentially in Asia which contributes 92% of the total world aquaculture production volume. The objective of this article is to define the contours of systemic typologies that are able to express the sustainability conditions of aquaculture systems. The proposed approach builds on surveys of aquaculture systems which differ in terms of their biogeographical nature (temperate/tropical and north/south countries) or their farming techniques and their governance systems. This work is a prerequisite to any attempt at an individualised and comparative evaluation of specific aquaculture systems from either global or territorial viewpoints. In order to go beyond the cleavage of a typology based on the differentiation between developed and developing countries, three typologies were produced. These typologies allow for discriminatory variables to be identified such as for example the marketing methods or the pace of innovation: a structural typology, a functional typology and a systemic typology. Finally, the representations of aquaculture activity and of its sustainability that producers have of the 4 different types that emerge from the systemic typology were recorded and analyzed
A new role for complement C3: regulation of antigen processing through an inhibitory activity.
International audienceIncreasing evidence underlines the involvement of complement component C3 in the establishment of acquired immunity which appears to play a complex role and to act at different levels. As antigen proteolysis by antigen presenting cells is a key event in the control of antigen presentation efficiency, and consequently in the quality of the immune response, we investigated whether C3 could modulate this step. Our results demonstrate for the first time that C3 can interfere with antigen proteolysis: (i) proteolysis of tetanus toxin (TT) by the lysosomal fraction from a human monocytic cell line (U937) is impaired in the presence of C3, (ii) this effect is C3-specific and involves the C3c fragment of the protein, (iii) C3c is effective even after disulfide disruption, but none of its three constitutive peptides is individually accountable for this inhibitory effect and (iv) the target-protease(s) exhibit(s) a serine-protease activity. The physiological relevance of our results is demonstrated by experiments showing a subcellular colocalisation of TT and C3 after their uptake by U937 and the reduction of TT proteolysis once internalised together with C3. These results highlight a novel role for C3 that broadens its capacity to modulate acquired immune response
- …