38 research outputs found

    EC80-873 Economic Analysis of Chemical, Ecofallow and Conventional Tillage System Wheat-Fallow Rotations

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    Extension circular 80-873 is about economic analysis of chemical, ecofalloe and conventional tillage system wheat- fallow rotations

    EC80-873 Economic Analysis of Chemical, Ecofallow and Conventional Tillage System Wheat-Fallow Rotations

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    Extension circular 80-873 is about economic analysis of chemical, ecofalloe and conventional tillage system wheat- fallow rotations

    Entry and exit in Missouri's swine industry by medium to large producers, 1964-1968

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    G80-505 Economics of Energy Used in Fallow Systems for Winter Wheat-Fallow Rotation

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    This NebGuide discusses the economic advantages of using a fallow system with winter wheat. In 1979, Americans watched gasoline, diesel, and other petroleum products dramatically increase in price. The amount of imported crude oil increased and the demand continued strong despite higher prices. Conservation of energy, either forced or voluntary, seems to be one of the key solutions to the energy crisis

    Neuropsychological Testing of Astronauts

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    The Spaceflight Cognitive Assessment Tool for Windows (WinSCAT) is a computer program that administers a battery of five timed neuro-cognitive tests. WinSCAT was developed to give astronauts an objective and automated means of assessing their cognitive functioning during space flight, as compared with their own baseline performances measured during similar prior testing on the ground. WinSCAT is also intended for use by flight surgeons to assess cognitive impairment after exposure of astronauts to such cognitive assaults as head trauma, decompression sickness, and exposure to toxic gas. The tests were selected from among a group of tests, denoted the Automated Neuropsychological Assessment Metrics, that were created by the United States Navy and Army for use in evaluating the cognitive impairment of military personnel who have been subjected to medication or are suspected to have sustained brain injuries. These tests have been validated in a variety of clinical settings and are now in the public domain. The tests are presented in a Microsoft Windows shell that facilitates administration and enables immediate reporting of test scores in numerical and graphical forms

    Using the 1.6um Bump to Study Rest-frame NIR Selected Galaxies at Redshift 2

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    We explore the feasibility and limitations of using the 1.6um bump as a photometric redshift indicator and selection technique and use it to study the rest-frame H-band galaxy luminosity and stellar mass functions at redshift z~2. We use publicly available Spitzer/IRAC images in the GOODS fields and find that color selection in the IRAC bandpasses alone is comparable in completeness and contamination to BzK selection. We find that the shape of the 1.6um bump is robust, and photometric redshifts are not greatly affected by choice of model parameters. Comparison with spectroscopic redshifts shows photometric redshifts to be reliable. We create a rest-frame NIR selected catalog of galaxies at z~2 and construct a galaxy stellar mass function (SMF). Comparisons with other SMFs at approximately the same redshift but determined using shorter wavelengths show good agreement. This agreement suggests that selection at bluer wavelengths does not miss a significant amount of stellar mass in passive galaxies. Comparison with SMFs at other redshifts shows evidence for the downsizing scenario of galaxy evolution. We conclude by pointing out the potential for using the 1.6um technique to select high-redshift galaxies with the JWST, whose lambda > 0.6 um coverage will not be well suited to selecting galaxies using techniques that require imaging at shorter wavelengths.Comment: Accepted for publication in Ap

    Radar-derived bed roughness characterization of Institute and Möller ice streams, West Antarctica, and comparison with Siple Coast ice streams

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    Subglacial bed conditions exert a significant control on ice stream behavior and evolution, and can be characterized by determining bed roughness from FFT analysis of radar-imaged basal reflectors. Here we assess bed roughness across Institute and Moller ice streams, West Antarctica, and compare our findings with bed roughness determined across the Siple Coast ice streams. We find that variations in bed roughness are spatially organized, and attribute this to the varying efficacy of subglacial erosion and deposition, with rougher (inland, slow-flowing) regions largely manifesting preglacial topography, and smoother (downstream, fast-flowing) regions evincing significant postglacial modification to the subglacial landscape. The observed similarities between bed roughness characteristics of IIS/MIS and the Siple ice streams suggest that IIS and MIS are largely underlain by wet, poorly consolidated sediments, and may therefore be vulnerable to the types of dynamical instabilities experienced by the Siple ice streams

    Disassembly and reassembly of human papillomavirus virus-like particles produces more virion-like antibody reactivity

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    <p>Abstract</p> <p>Background</p> <p>Human papillomavirus (HPV) vaccines based on major capsid protein L1 are licensed in over 100 countries to prevent HPV infections. The yeast-derived recombinant quadrivalent HPV L1 vaccine, GARDASIL(R), has played an important role in reducing cancer and genital warts since its introduction in 2006. The L1 proteins self-assemble into virus-like particles (VLPs).</p> <p>Results</p> <p>VLPs were subjected to post-purification disassembly and reassembly (D/R) treatment during bioprocessing to improve VLP immunoreactivity and stability. The post-D/R HPV16 VLPs and their complex with H16.V5 neutralizing antibody Fab fragments were visualized by cryo electron microscopy, showing VLPs densely decorated with antibody. Along with structural improvements, post-D/R VLPs showed markedly higher antigenicity to conformational and neutralizing monoclonal antibodies (mAbs) H16.V5, H16.E70 and H263.A2, whereas binding to mAbs recognizing linear epitopes (H16.J4, H16.O7, and H16.H5) was greatly reduced.</p> <p>Strikingly, post-D/R VLPs showed no detectable binding to H16.H5, indicating that the H16.H5 epitope is not accessible in fully assembled VLPs. An atomic homology model of the entire</p> <p>HPV16 VLP was generated based on previously determined high-resolution structures of bovine papillomavirus and HPV16 L1 pentameric capsomeres.</p> <p>Conclusions</p> <p>D/R treatment of HPV16 L1 VLPs produces more homogeneous VLPs with more virion-like antibody reactivity. These effects can be attributed to a combination of more complete and regular assembly of the VLPs, better folding of L1, reduced non-specific disulfide-mediated aggregation and increased stability of the VLPs. Markedly different antigenicity of HPV16 VLPs was observed upon D/R treatment with a panel of monoclonal antibodies targeting neutralization sensitive epitopes. Multiple epitope-specific assays with a panel of mAbs with different properties and epitopes are required to gain a better understanding of the immunochemical properties of VLPs and to correlate the observed changes at the molecular level. Mapping of known antibody epitopes to the homology model explains the changes in antibody reactivity upon D/R. In particular, the H16.H5 epitope is partially occluded by intercapsomeric interactions involving the L1 C-terminal arm. The homology model allows a more precise mapping of antibody epitopes. This work provides a better understanding of VLPs in current vaccines and could guide the design of improved vaccines or therapeutics.</p

    EC7-864 The Economics of Hybrid Wheat

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    Extension Circular 76-864 discusses the Economics of Hybrid Wheat
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