4,685 research outputs found
Food-induced fatal anaphylaxis: from epidemiological data to general prevention strategies
BACKGROUND: Anaphylaxis hospitalisations are increasing in many countries, in particular for medication and food triggers in young children. Food-related anaphylaxis remains an uncommon cause of death, but a significant proportion of these are preventable. AIM: To review published epidemiological data relating to food-induced anaphylaxis and potential risk factors of fatal and/or near-fatal anaphylaxis cases, in order to provide strategies to reduce the risk of severe adverse outcomes in food anaphylaxis. METHODS: We identified 32 published studies available in MEDLINE (1966-2017), EMBASE (1980-2017), CINAHL (1982-2017), using known terms and synonyms suggested by librarians and allergy specialists. RESULTS: Young adults with a history of asthma, previously known food allergy particularly to peanut/tree nuts are at higher risk of fatal anaphylaxis reactions. In some countries, cow's milk and seafood/fish are also becoming common triggers of fatal reactions. Delayed adrenaline injection is associated with fatal outcomes, but timely adrenaline alone may be insufficient. There is still a lack of evidence regarding the real impact of these risk factors and co-factors (medications and/or alcohol consumption, physical activities, and mast cell disorders). CONCLUSIONS: General strategies should include optimization of the classification and coding for anaphylaxis (new ICD 11 anaphylaxis codes), dissemination of international recommendations on the treatment of anaphylaxis, improvement of the prevention in food and catering areas and, dissemination of specific policies for allergic children in schools. Implementation of these strategies will involve national and international support for ongoing local efforts in relationship with networks of centres of excellence to provide personalized management (which might include immunotherapy) for the most at-risk patients. This article is protected by copyright. All rights reserved
Search for R-parity Violating Supersymmetry in Dimuon and Four-Jets Channel
We present results of a search for R-parity-violating decay of the neutralino
chi_1^0, taken to be the Lightest Supersymmetric Particle. It is assumed that
this decay proceeds through one of the lepton-number violating couplings
lambda-prime_2jk (j=1,2; k=1,2,3). This search is based on 77.5 pb-1 of data,
collected by the D0 experiment at the Fermilab Tevatron in ppbar collisions at
a center of mass energy of 1.8 TeV in 1992-1995.Comment: 10 pages, 3 figure
Search for New Physics Using Quaero: A General Interface to D0 Event Data
We describe Quaero, a method that i) enables the automatic optimization of
searches for physics beyond the standard model, and ii) provides a mechanism
for making high energy collider data generally available. We apply Quaero to
searches for standard model WW, ZZ, and ttbar production, and to searches for
these objects produced through a new heavy resonance. Through this interface,
we make three data sets collected by the D0 experiment at sqrt(s)=1.8 TeV
publicly available.Comment: 7 pages, submitted to Physical Review Letter
Measurements of differential cross sections of Z/gamma*+jets+X events in proton anti-proton collisions at sqrt{s}=1.96 TeV
We present cross section measurements for Z/gamma*+jets+X production,
differential in the transverse momenta of the three leading jets. The data
sample was collected with the D0 detector at the Fermilab Tevatron proton
anti-proton collider at a center-of-mass energy of 1.96 TeV and corresponds to
an integrated luminosity of 1 fb-1. Leading and next-to-leading order
perturbative QCD predictions are compared with the measurements, and agreement
is found within the theoretical and experimental uncertainties. We also make
comparisons with the predictions of four event generators. Two
parton-shower-based generators show significant shape and normalization
differences with respect to the data. In contrast, two generators combining
tree-level matrix elements with a parton shower give a reasonable description
of the the shapes observed in data, but the predicted normalizations show
significant differences with respect to the data, reflecting large scale
uncertainties. For specific choices of scales, the normalizations for either
generator can be made to agree with the measurements.Comment: Published in PLB. 11 pages, 3 figure
Search for charged Higgs bosons decaying to top and bottom quarks in ppbar collisions
We describe a search for production of a charged Higgs boson, q \bar{q'} ->
H^+, reconstructed in the t\bar{b} final state in the mass range 180 <= M_{H^+}
<= 300 GeV. The search was undertaken at the Fermilab Tevatron collider with a
center-of-mass energy sqrt{s} = 1.96 TeV and uses 0.9 fb^{-1} of data collected
with the D0 detector. We find no evidence for charged Higgs boson production
and set upper limits on the production cross section in the Types I, II and III
two-Higgs-doublet models (2HDMs). An excluded region in the (M_{H^+},tan\beta)
plane for Type I 2HDM is presented.Comment: Submitted to Phys. Rev. Letter
Simultaneous measurement of the ratio B(t->Wb)/B(t->Wq) and the top quark pair production cross section with the D0 detector at sqrt(s)=1.96 TeV
We present the first simultaneous measurement of the ratio of branching
fractions, R=B(t->Wb)/B(t->Wq), with q being a d, s, or b quark, and the top
quark pair production cross section sigma_ttbar in the lepton plus jets channel
using 0.9 fb-1 of ppbar collision data at sqrt(s)=1.96 TeV collected with the
D0 detector. We extract R and sigma_ttbar by analyzing samples of events with
0, 1 and >= 2 identified b jets. We measure R = 0.97 +0.09-0.08 (stat+syst) and
sigma_ttbar = 8.18 +0.90-0.84 (stat+syst)} +/-0.50 (lumi) pb, in agreement with
the standard model prediction.Comment: submitted to Phys.Rev.Letter
Search for dark photons from supersymmetric hidden valleys
We search for a new light gauge boson, a dark photon, with the D0 experiment.
In the model we consider, supersymmetric partners are pair produced and cascade
to lightest neutralinos that can decay into the hidden sector state plus either
a photon or a dark photon. The dark photon decays through its mixing with a
photon into fermion pairs. We therefore investigate a previously unexplored
final state that contains a photon, two spatially close leptons, and large
missing transverse energy. We do not observe any evidence for dark photons and
set a limit on their production.Comment: submitted to PR
Observation of ZZ production in ppbar collisions at sqrt(s) = 1.96 TeV
We present an observation for ZZ -> l+l-l'+l'- (l, l' = e or mu) production
in ppbar collisions at a center-of-mass energy of sqrt(s) = 1.96 TeV. Using 1.7
fb-1 of data collected by the D0 experiment at the Fermilab Tevatron Collider,
we observe three candidate events with an expected background of 0.14 +0.03
-0.02 events. The significance of this observation is 5.3 standard deviations.
The combination of D0 results in this channel, as well as in ZZ -> l+l-nunubar,
yields a significance of 5.7 standard deviations and a combined cross section
of sigma(ZZ) = 1.60 +/- 0.63 (stat.) +0.16 -0.17 (syst.) pb.Comment: 7 pages, 1 figure, 2 tables Modified slightly following review
proces
Search for CP violation in semileptonic Bs decays
We have performed a search for CP violation in a sample of Bs -> Ds mu X
decays corresponding to ~fb of proton-antiproton collisions collected
by the D0 detector in Run~II at the Fermilab Tevatron Collider. New physics in
mixing could contribute a significant CP violating weak phase, which
would be observed as a difference in the decay-time distribution for oscillated states versus that for . A fit
to the decay-time distributions of the candidates yields
the flavor-specific asymmetry , which
excludes CP violation due to new physics within the experimental sensitivity.Comment: published in Phys. Rev.
Measurement of the forward-backward charge asymmetry and extraction of sin^2Theta^{eff}_W in ppbar -> Z/\gamma^{*}+X -> e+e+X events produced at \sqrt{s}=1.96 TeV
We present a measurement of the forward-backward charge asymmetry ()
in events at a center-of-mass energy
of 1.96 TeV using 1.1 fb of data collected with the D0 detector at the
Fermilab Tevatron collider. is measured as a function of the invariant
mass of the electron-positron pair, and found to be consistent with the
standard model prediction. We use the measurement to extract the
effective weak mixing angle .Comment: 7 Pages, 1 Figure, 3 Tables, Accepted by Phys. Rev. Let
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