A Community of Protests: Social Space as a Field Site

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Medindo o sexismo: Fatos, dados e ajustes

Nesse artigo publicado na Revista ArtNews em maio de 2015, a autora expõe dados estatísticos que sustentam uma prática sexista no campo das artes, que muitas vezes tende a nos passar despercebida, sendo normatizada por todos. Ela analisa as ausências da produção das mulheres artistas em mostras individuais, coleções permanentes, divulgação em imprensa, representação em galerias e também a disparidade de valores de mercado. Também propõe táticas de reversão desse panorama e cita diversos projetos engajados na ampliação de uma postura crítica ancorada na experiência da mulher, a fim de possibilitar um rompimento com as formas de segregação epistêmica que fazem parte do campo artístico contemporâneo

Opposing Roles for Membrane Bound and Soluble Fas Ligand in Glaucoma-Associated Retinal Ganglion Cell Death

Glaucoma, the most frequent optic neuropathy, is a leading cause of blindness worldwide. Death of retinal ganglion cells (RGCs) occurs in all forms of glaucoma and accounts for the loss of vision, however the molecular mechanisms that cause RGC loss remain unclear. The pro-apoptotic molecule, Fas ligand, is a transmembrane protein that can be cleaved from the cell surface by metalloproteinases to release a soluble protein with antagonistic activity. Previous studies documented that constitutive ocular expression of FasL maintained immune privilege and prevented neoangeogenesis. We now show that FasL also plays a major role in retinal neurotoxicity. Importantly, in both TNFα triggered RGC death and a spontaneous model of glaucoma, gene-targeted mice that express only full-length FasL exhibit accelerated RGC death. By contrast, FasL-deficiency, or administration of soluble FasL, protected RGCs from cell death. These data identify membrane-bound FasL as a critical effector molecule and potential therapeutic target in glaucoma

MRI data-driven algorithm for the diagnosis of behavioural variant frontotemporal dementia

Introduction: Structural brain imaging is paramount for the diagnosis of behavioural variant of frontotemporal dementia (bvFTD), but it has low sensitivity leading to erroneous or late diagnosis. Methods: A total of 515 subjects from two different bvFTD cohorts (training and independent validation cohorts) were used to perform voxel-wise morphometric analysis to identify regions with significant differences between bvFTD and controls. A random forest classifier was used to individually predict bvFTD from deformation-based morphometry differences in isolation and together with semantic fluency. Tenfold cross validation was used to assess the performance of the classifier within the training cohort. A second held-out cohort of genetically confirmed bvFTD cases was used for additional validation. Results: Average 10-fold cross-validation accuracy was 89% (82% sensitivity, 93% specificity) using only MRI and 94% (89% sensitivity, 98% specificity) with the addition of semantic fluency. In the separate validation cohort of definite bvFTD, accuracy was 88% (81% sensitivity, 92% specificity) with MRI and 91% (79% sensitivity, 96% specificity) with added semantic fluency scores. Conclusion: Our results show that structural MRI and semantic fluency can accurately predict bvFTD at the individual subject level within a completely independent validation cohort coming from a different and independent database

Curatorial Activism : Towards an Ethics of Curating

"Despite decades of postcolonial, feminist, anti-racist and queer activism and theorizing, the art world continues to exclude ‘Other’ artists – those who are women, of colour and LGBTQ. Indeed, the more closely one examines the numbers, the more glaring it becomes that white, Euro-American, heterosexual, privileged and, above all, male artists continue to dominate the art world. The fight for gender and race equality continues apace. Focusing on themes of feminism, race and sexuality, Curatorial Activism examines the pioneering exhibitions that have broken down boundaries and demonstrated that new approaches are possible, from Nochlin’s ‘Women Artists’ at the LACMA in the mid-1970s to Martin’s ‘Carambolages’ in 2016 at the Grand Palais in Paris. By exposing both the disparities and inclusive solutions, Reilly addresses the urgent need in the contemporary art world for curatorial strategies that provide alternatives to exclusionary models of collecting and display. In so doing, she provides an invaluable source of information for current thinkers and, in a world dominated by visual culture, a vital source of inspiration for today’s ever-expanding new generation of curators." -- Publisher's web site

Ghada Amer : Color Misbehavior

No Full Tex

Exploring the Relationship Between Food Insecurity, Mental Health, and Physical Health in Hispanic Parents in California

Background: Food insecurity, the inability to access and consume healthy foods, is a significant issue in the United States. In 2019, 10.5% (13.7 million) U.S. households experienced one or more episodes of food insecurity during the previous 12 months. Immigrant-headed households and Hispanic-headed households experience food insecurity at higher rates than the general public. Food insecurity is associated with multiple risk factors including household economics, food accessibility, and neighborhood environment. Additionally, food insecurity is associated with numerous negative physical and mental health outcomes across all ages. California is home to one-quarter of the U.S. foreign-born population. Half of California’s immigrant residents were born in Latin America. This study seeks to examine the relationship of access to fruits and vegetables, foreign-born status, neighborhood social environment, and food insecurity among Hispanic parents in California. Further analysis will examine the relationship of food insecurity to physical and mental health outcomes in the same group. Methods: This study conducted a cross-sectional analysis of adult data from the 2017 and 2018 California Health Interview Survey (CHIS) Public Use Files. The sample included 2,532 adults who self-identified as Hispanic and parents or legal guardians of children under 18. Food insecurity was measured by a single household food security item from the CHIS adult survey. Univariate and multivariable logistic regressions were conducted to test associations of access to fruits and vegetables, foreign-born status, and neighborhood social environment to food insecurity. In the second analysis, mental health was measured using the Kessler 6-Item Psychological Distress Scale. Physical health was measured using a single item which asked the respondent to rate their health as excellent, very good, fair, or poor. Univariate and multivariable logistic regressions were conducted to test the association of food insecurity to mental and physical health. Results: Within the previous twelve months 26.9% of Hispanic parents reported experiencing one or more episodes of food insecurity. Parents living in neighborhoods with higher social cohesion were less likely to be food insecure (OR 0.69; 95% CI 0.56, 0.85). Parents who reported feeling safe only sometimes or not at all were more likely to be food insecure (OR 1.36; 95% CI 1.02, 1.81). Parents who can only sometimes find fresh fruits and vegetables in their neighborhood were more likely to be food insecure (OR 1.68; 95% CI 1.20, 2.34). Conversely, the risk for food insecurity among parents who never find fresh fruits and vegetables was similar to parents who can usually/always find fresh fruits and vegetables (OR 0.85; 95% CI 0.48, 1.52). Foreign-born status was not significantly related to food insecurity in this sample (OR 1.01; 95% CI 0.80, 1.28). Most parents (78.4%) rated their health as good, very good, or excellent. Overall, few parents (7.8%) had experienced psychological distress in the previous 12 months. Food insecure parents were less likely to report good health than food secure parents (OR 0.62; 95% CI 0.50, 0.78). Parents who experienced distress in the last year were less likely to report good health compared to parents who did not experience distress (OR 0.27; 95% CI 0.20, 0.38). Parents who had experienced food insecurity were 2.6 times as likely to report distress in the last 12 months compared to those who were food secure (OR 2.62; 95% CI 1.80, 3.82). Parents who self-reported good health were less likely to report distress in the last 12 months as compared to parents who reported poor health (OR 0.27; 95% CI 0.19, 0.37). Overall, few parents (7.8%) had experienced psychological distress in the previous 12 months. Food insecure parents were less likely to report good health than food secure parents (OR 0.62; 95% CI 0.50, 0.78). Parents who experienced distress in the last year were less likely to report good health compared to parents who did not experience distress (OR 0.27; 95% CI 0.20, 0.38). Parents who had experienced food insecurity were 2.6 times as likely to report distress in the last 12 months compared to those who were food secure (OR 2.62; 95% CI 1.80, 3.82). Parents who self-reported good health were less likely to report distress in the last 12 months as compared to parents who reported poor health (OR 0.27; 95% CI 0.19, 0.37). Conclusion: A positive neighborhood social environment was associated with a reduced likelihood of experiencing food insecurity after accounting for potential confounding variables. Food insecurity was significantly related to physical health and parental distress after accounting for potential confounding variables. Future efforts to reduce food insecurity should address social and neighborhood level factors in addition to economic factors

Quantifying pediatric patient need for second- and third-line HIV treatment: A tool for decision-making in resource-limited settings.

As national HIV programs across the world mature and continue to scale up towards UNAIDS' 90-90-90 targets, it is increasingly important to accurately estimate HIV treatment needs in pediatric patient populations to prepare for anticipated increases in demand. This is particularly vital in sub-Saharan Africa, where the bulk of the global pediatric HIV burden remains concentrated, and for treatment-experienced populations, for which data are severely limited. This article discusses the conceptual framework behind and application of a five-year country-level quantification and decision-making tool aimed at providing national HIV programs and their partners with a better understanding of their evolving national HIV treatment and programming needs for second-and third-line pediatric populations. The conceptual framework of the algorithm which undergirds the tool is the patient pathway, along which key influencing factors that determine whether pediatric HIV patients are linked to care, remain in treatment, and are appropriately switched to later lines of treatment are accounted for quantitatively. Excel-based and arithmetic, the algorithm is designed to use available national, regional, and global data for factors impacting patient estimates including treatment coverage; routine viral load testing; viral load non-suppression; confirmed treatment failure; and patient loss to follow up-outcomes for which data are generally very limited in this patient population. The ultimate output of the tool is an estimate of the aggregate annual number of patients by treatment line. Given the limitations in available data for pediatric HIV, particularly for patients on second- and third-line treatments, this tool may help fill a data gap by providing a mechanism for policymakers to scenario plan, thus aiding resource allocation decisions for pediatric HIV program scale-up. The tool may be used to streamline national antiretroviral procurement of later lines of treatment, especially in resource-limited settings, and may also be used to add value to broader HIV policy and planning processes at the national level

O que é ativismo curatorial?

Translation of the first chapter of the book Curatorial Activism: Towards an Ethics of Curating (Thames & Hudson, 2018) by Maura Reilly.Traducción del primer capítulo del libro Curatorial Activism: Towards an Ethics of Curating (Thames & Hudson, 2018), de Maura Reilly.Tradução do primeiro capítulo do livro Curatorial Activism: Towards an Ethics of Curating (Thames & Hudson, 2018), de Maura Reilly

Election Reform and Women's Representation: Ranked Choice Voting in the U.S.

Ranked choice voting first gained a foothold in the U.S. during the Progressive Movement in the 20th century as calls for electoral reforms grew. Ranked choice voting was implemented in many cities across the U.S. in both single- and multi-seat districts. But, by the 1940s it became a victim of its own success, turning the tides of the hegemonic white male leadership in U.S. legislative bodies with the election of women. Since the 1990s, ranked choice voting has once again gained traction in the U.S., this time with the focus on implementing single seat ranked choice voting. This article will build on the existing literature by filling in the gaps on how ranked choice voting - in both forms - has impacted women’s representation both historically and in currently elected bodies in the U.S