A method of characteristics solution for the equations governing the unsteady flow of liquids in closed systems

Method of characteristics solution for equations governing unsteady flow of liquids in closed system

Genomic Variation: What Does It Mean?

New technologies have given us the ability to detect genomic variation at resolutions 50-100 times greater than earlier tests. The good news is that we can now detect variations that help explain developmental delays, autism, or multiple congenital anomalies in up to 20% of children. The bad news is that we can also detect small missing or extra pieces of chromosomes that remain unexplained: that is, we don’t know whether they have any clinical significance at all. The rapid pace of technological change may have outpaced the lab’s ability to interpret, providers’ abilities to explain, and patients’ abilities to understand the test results. This Issue Brief summarizes a series of studies examining the uncertainties revolving around chromosomal microarray testing, which has become the new standard of practice in genetic testing of children with unexplained anomalies

Electrostatic protection of the Solar Power Satellite and rectenna

Several features of the interactions of the solar power satellite (SPS) with its space environment were examined theoretically. The voltages produced at various surfaces due to space plasmas and the plasma leakage currents through the kapton and sapphire solar cell blankets were calculated. At geosynchronous orbit, this parasitic power loss is only 0.7%, and is easily compensated by oversizing. At low-Earth orbit, the power loss is potentially much larger (3%), and anomalous arcing is expected for the EOTV high voltage negative surfaces. Preliminary results of a three dimensional self-consistent plasma and electric field computer program are presented, confirming the validity of the predictions made from the one dimensional models. Magnetic shielding of the satellite, to reduce the power drain and to protect the solar cells from energetic electron and plasma ion bombardment is considered. It is concluded that minor modifications can allow the SPS to operate safely and efficiently in its space environment. The SPS design employed in this study is the 1978 MSFC baseline design utilizing GaAs solar cells at CR-2 and an aluminum structure

Propulsion and Space Vehicle Systems Analysis Program Tensor I, volume I Technical report no. 341

Computer program for space vehicle and propulsion systems analysi

APPEL: An Adaptable and Programmable Policy Environment and Language

The Accent project (Advanced Component Control Enhancing Network Technologies) developed a practical and comprehensive policy system for call control/Internet telephony. The policy system has subsequently been extended for management of sensor networks/wind farms and of home care/telecare. This report focuses on Appel (Adaptable and Programmable Policy Environment and Language). It provides an overview of the language, and presents the language in XML schema form. The core language has been instantiated for call control, for sensor networks, and for home care. Sample goals and policies of different kinds are provided to illustrate these applications

Incidence of Huanglongbing on several sweet orange cultivars budded onto different rootstocks at the Citrus Experimental Station (EECB), Bebedouro, São Paulo, Brazil.

Huanglongbing (HLB), caused by Candidatus Liberibacter asiaticus and Ca. L. americanus and vectored by Diaphorina citri Kuwayama, was first reported in 2004 in Brazil and it is currently widespread in São Paulo State (Belasque et al., 2010). The EECB, in partnership with Embrapa Cassava & Fruits, conducts a citrus improvement program aimed to select scion and rootstock Citrus cultivars mainly focused on the resistance or tolerance to biotic and abiotic stresses

Cusp energetic particle events: Implications for a major acceleration region of the magnetosphere

The Charge and Mass Magnetospheric Ion Composition Experiment (CAMMICE) on board the Polar spacecraft observed 75 energetic particle events in 1996 while the satellite was at apogee. All of these events were associated with a decrease in the magnitude of the local magnetic field measured by the Magnetic Field Experiment (MFE) on Polar. These new events showed several unusual features: (1) They were detected in the dayside polar cusp near the apogee of Polar with about 79% of the total events in the afternoonside and 21% in the morningside; (2) an individual event could last for hours; (3) the measured helium ion had energies up to and many times in excess of 2.4 MeV; (4) the intensity of 1–200 KeV/e helium was anticorrelated with the magnitude of the local geomagnetic field but correlated with the turbulent magnetic energy density; (5) the events were associated with an enhancement of the low-frequency magnetic noise, the spectrum of which typically extends from a few hertz to a few hundreds of hertz as measured by the Plasma Wave Instrument (PWI) on Polar; and (6) a seasonal variation was found for the occurrence rate of the events with a maximum in September. These characterized a new phenomenon which we are calling cusp energetic particle (CEP) events. The observed high charge state of helium and oxygen ions in the CEP events indicates a solar source for these particles. Furthermore, the measured 0.52–1.15 MeV helium flux was proportional to the difference between the maximum and the minimum magnetic field in the event. A possible explanation is that the energetic helium ions are energized from lower energy helium by a local acceleration mechanism associated with the high-altitude dayside cusp. These observations represent a potential discovery of a major acceleration region of the magnetosphere

Part Variation Modeling to Avoid Scrap Parts in Multi-stage Production Systems

Manufacturing systems for today's products are complex systems requiring a variety of different processes in order to be able to manufacture all necessary part features. This also applies to the production of rotating components, which have experienced increasing demand at the latest due to the growth in mobility. As in almost every manufacturing process, quality-reducing defects can occur due to deviations for example tool wear, which cannot always be avoided. Those, that have accumulated from previous process steps can cause the occurrence of superimposed defects. This leads to complex relationships between quality defects in the end product and the numerous parameters of the manufacturing processes. To remain competitive, production must be optimized in order to identify defects as early as possible, as well as their dependencies and variation patterns. The paper presents an approach to identify and model part variations within multi-stage production systems. Subsequently, based on a detected deviation, a downstream compensation strategy can be proposed at an early stage of the manufacturing process, which uses the capability of the overall system to fundamentally eliminate rejects

Decreasing Clostridium Difficile Health Care - Associated Infections Through Use of a Launderable Mattress Cover

BACKGROUND: The annual incidence of Clostridium difficile infection (CDI) in the United States is estimated to be 330,000 cases. We evaluated the impact of using a launderable mattress and bed deck cover on the incidence of hospital-onset CDI in two long-term acute care hospitals (LTACH)s. METHODS: Two LTACH hospitals began using a launderable mattress and bed deck cover on beds starting in May of 2013. One facility had 74 beds and the other had 30 beds. Covers were changed after every patient. The covers were laundered using hot water, detergent, and chlorine. Rates for CDIs were compared using Poisson regression between the 16 months before use of the launderable cover and the 14 months after the cover started being used. RESULTS: At Hospital A, the use of bedcovers reduced the rate of infections by 47.8% (95% CI 47.1 – 48.6), controlling for the rate of hand washing compliance and length of stay in days. At Hospital B, the use of bedcovers reduced the rate of infections by 50% (95% CI 47.5 – 52.7), controlling for the rate of hand washing compliance and length of stay in days. CONCLUSIONS: The use of a launderable cover for mattresses and bed decks of hospital beds was associated with a decreased rate of healthcare associated CDIs in two LTACHs

NuGO contributions to GenePattern

NuGO, the European Nutrigenomics Organization, utilizes 31 powerful computers for, e.g., data storage and analysis. These so-called black boxes (NBXses) are located at the sites of different partners. NuGO decided to use GenePattern as the preferred genomic analysis tool on each NBX. To handle the custom made Affymetrix NuGO arrays, new NuGO modules are added to GenePattern. These NuGO modules execute the latest Bioconductor version ensuring up-to-date annotations and access to the latest scientific developments. The following GenePattern modules are provided by NuGO: NuGOArrayQualityAnalysis for comprehensive quality control, NuGOExpressionFileCreator for import and normalization of data, LimmaAnalysis for identification of differentially expressed genes, TopGoAnalysis for calculation of GO enrichment, and GetResultForGo for retrieval of information on genes associated with specific GO terms. All together, these NuGO modules allow comprehensive, up-to-date, and user friendly analysis of Affymetrix data. A special feature of the NuGO modules is that for analysis they allow the use of either the standard Affymetrix or the MBNI custom CDF-files, which remap probes based on current knowledge. In both cases a .chip-file is created to enable GSEA analysis. The NuGO GenePattern installations are distributed as binary Ubuntu (.deb) packages via the NuGO repository