745 research outputs found

    PhyloPat: an updated version of the phylogenetic pattern database contains gene neighborhood

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    Phylogenetic patterns show the presence or absence of certain genes in a set of full genomes derived from different species. They can also be used to determine sets of genes that occur only in certain evolutionary branches. Previously, we presented a database named PhyloPat which allows the complete Ensembl gene database to be queried using phylogenetic patterns. Here, we describe an updated version of PhyloPat which can be queried by an improved web server. We used a single linkage clustering algorithm to create 241 697 phylogenetic lineages, using all the orthologies provided by Ensembl v49. PhyloPat offers the possibility of querying with binary phylogenetic patterns or regular expressions, or through a phylogenetic tree of the 39 included species. Users can also input a list of Ensembl, EMBL, EntrezGene or HGNC IDs to check which phylogenetic lineage any gene belongs to. A link to the FatiGO web interface has been incorporated in the HTML output. For each gene, the surrounding genes on the chromosome, color coded according to their phylogenetic lineage can be viewed, as well as FASTA files of the peptide sequences of each lineage. Furthermore, lists of omnipresent, polypresent, oligopresent and anticorrelating genes have been included. PhyloPat is freely available at http://www.cmbi.ru.nl/phylopat

    A four‐component classification of uncertainties in biological invasions: implications for management

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    Although uncertainty is an integral part of any science, it raises doubts in public perception about scientific evidence, is exploited by denialists, and therefore potentially hinders the implementation of management actions. As a relatively young field of study, invasion science contains many uncertainties. This may explain why, despite international policies aimed at mitigating biological invasions, the implementation of national- and regional-scale measures to prevent or control alien species has done little to slow the increase in extent of invasions and the magnitude of impacts. Uncertainty is therefore a critical aspect of invasion science that should be addressed to enable the field to progress further. To improve how uncertainties in invasion science are captured and characterized, we propose a framework, which is also applicable to other applied research fields such as climate and conservation science, divided into four components: the need (1) to clearly circumscribe the phenomenon, (2) to measure and provide evidence for the phenomenon (i.e., confirmation), (3) to understand the mechanisms that cause the phenomenon, and (4) to understand the mechanisms through which the phenomenon results in consequences. We link these issues to three major types of uncertainty: linguistic, psychological, and epistemic. The application of this framework shows that the four components tend to be characterized by different types of uncertainty in invasion science.We explain how these uncertainties can be detrimental to the implementation of management measures and propose ways to reduce them. Since biological invasions are increasingly tightly embedded in complex socio-ecological systems, many problems associated with these uncertainties have convoluted solutions. They demand the consensus of many stakeholders to define and frame the dimensions of the phenomenon, and to decide on appropriate actions. While many of the uncertainties cannot be eliminated completely, we believe that using this framework to explicitly identify and communicate them will help to improve collaboration between researchers and managers, increase scientific, political, and public support for invasion research, and provide a stronger foundation for sustainable management strategies

    A regularity class for the roots of nonnegative functions

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    We investigate the regularity of the positive roots of a non-negative function of one-variable. A modified H\"older space Fβ\mathcal{F}^\beta is introduced such that if fFβf\in \mathcal{F}^\beta then fαCαβf^\alpha \in C^{\alpha \beta}. This provides sufficient conditions to overcome the usual limitation in the square root case (α=1/2\alpha = 1/2) for H\"older functions that f1/2f^{1/2} need be no more than C1C^1 in general. We also derive bounds on the wavelet coefficients of fαf^\alpha, which provide a finer understanding of its local regularity.Comment: 12 page

    Anisotropic optical properties of single-crystal GdBa2Cu3O7-delta

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    The optical spectrum of reduced-T(c) GdBa2Cu3O7-delta has been measured for polarizations parallel and perpendicular to the ab plane. The sample was an oxygen-deficient single crystal with a large face containing the c axis. The polarized reflectance from this face was measured from 20-300 K in the spectral region from 30-3000 cm-1, with 300 K data to 30 000 cm-1. Kramers-Kronig analysis was used to determine the spectral dependence of the ab and the c components of the dielectric tensor. The optical properties are strongly anisotropic. The ab-plane response resembles that of other reduced-T(c) materials whereas the c axis, in contrast, shows only the presence of several phonons. There is a complete absence of charge carrier response along c above and below T(c). This observation allows us to set an upper limit to the free-carrier spectral weight for transport perpendicular to the CuO2 planes

    Age related decline in female lar gibbon great call performance suggests that call features correlate with physical condition

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    Background: White-handed gibbons (Hylobates lar) are small Asian apes known for living in stable territories and producing loud, elaborate vocalizations (songs), often in well-coordinated male/female duets. The female great call, the most conspicuous phrase of the repertoire, has been hypothesized to function in intra-sexual territorial defense. We therefore predicted that characteristics of the great call would correlate with a caller’s physical condition, and thus might honestly reflect resource holding potential (RHP). Because measurement of RHP is virtually impossible for wild animals, we used age as a proxy, hypothesizing that great call climaxes are difficult to produce and maintain over time, and that older adults will therefore perform lower quality great calls than young adults. To test this we analyzed the great call climaxes of 15 wild lar gibbon females at Khao Yai National Park, Thailand and 2 captive females at Leo Conservation Center, Greenwich, CT. Results: Findings show that call climaxes correlate with female age, as young animals (n = 8, mean age: 12.9 years) produced climaxes with a higher frequency range (delta F0), maximum F0 frequency and duty cycle than old animals (n = 9, mean age: 29.6 years). A permuted discriminant function analysis also correctly classified calls by age group. During long song bouts the maximum F0 frequency of great call climaxes’ also decreased. Additional data support the hypothesis that short high notes, associated with rapid inhalation as an individual catches its breath, reflect increased caller effort. Older females produced more high notes than younger females, but the difference only approached statistical significance, suggesting that calling effort may be similar across different ages. Finally, for the first time in this species, we measured peak intensity of calls in captive females. They were capable of producing climaxes in excess of 100 dB at close range (2.7 m). Conclusions: Age and within-bout differences in the lar gibbon great call climax suggest that call features correlate with physical condition and thus the call may have evolved as an honest signal in the context of intra-sexual territorial defense and possibly also in male mate choice via sexual selection, although further testing of these hypotheses is necessary. Results: Findings show that call climaxes correlate with female age, as young animals (n = 8, mean age: 12.9 years) produced climaxes with a higher frequency range (delta F0), maximum F0 frequency and duty cycle than old animals (n = 9, mean age: 29.6 years). A permuted discriminant function analysis also correctly classified calls by age group. During long song bouts the maximum F0 frequency of great call climaxes’ also decreased. Additional data support the hypothesis that short high notes, associated with rapid inhalation as an individual catches its breath, reflect increased caller effort. Older females produced more high notes than younger females, but the difference only approached statistical significance, suggesting that calling effort may be similar across different ages. Finally, for the first time in this species, we measured peak intensity of calls in captive females. They were capable of producing climaxes in excess of 100 dB at close range (2.7 m). Conclusions: Age and within-bout differences in the lar gibbon great call climax suggest that call features correlate with physical condition and thus the call may have evolved as an honest signal in the context of intra-sexual territorial defense and possibly also in male mate choice via sexual selection, although further testing of these hypotheses is necessary

    A Catalog of Broad Absorption Line Quasars from the Sloan Digital Sky Survey Early Data Release

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    We present a catalog of 224 broad absorption line quasars (BALQSOs) from the Sloan Digital Sky Survey's Early Data Release Quasar Catalog, including a relatively complete and homogeneous subsample of 131 BALQSOs. Since the identification of BALQSOs is subject to considerable systematic uncertainties, we attempt to create a complete sample of SDSS BALQSOs by combining the results of two automated selection algorithms and a by-eye classification scheme. One of these automated algorithms finds broad absorption line troughs by comparison with a composite quasar spectrum. We present the details of this algorithm and compare this method to that which uses a power-law fit to the continuum. The BALQSOs in our sample are further classified as high-ionization BALQSOs (HiBALs), low-ionization BALQSOs (LoBALs), and BALQSOs with excited iron absorption features (FeLoBALs); composite spectra of each type are presented. We further present a study of the properties of the BALQSOs in terms of the balnicity distribution, which rises with decreasing balnicity. This distribution of balnicities suggests that the fraction of quasars with intrinsic outflows may be significantly underestimated.Comment: 36 pages, 7 figures (1 color), 2 tables, accepted by A

    Fruit crops 1990: a summary of research

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    Orchard temperature profiles in spring frost conditions / R. D. Brazee, R. D. Fox and D. C. Ferree -- Orchard sprayers: how much spray moves out of the orchard? / R. D. Fox, D. L. Reichard, R. D. Brazee, and F. R. Hall -- Influence of pruning treatments on mature spur-bound 'Starkrimson Delicious' apple trees / D. C. Ferree, J. C. Schmid, J. R. Schupp and I. J. Warrington -- The winter of 1983-84: a test winter for Ohio's fruit crops / C. K. Chandler and D. C. Ferree -- Performance of apple roostock, cultivars and cultural treatments under the stress of the 1988 drought / D. C. Ferree and J. C. Schmid -- Performance of a spur and standard Delicious strain in a slender spindle system / D. C. Ferree and J. C. Schmid -- Survey of Ohio strawberry growers: present practice and future directions / J. C. Scheerens and G. L. Brenneman -- Orchard crop loss assessments: a precondition for improved crop protection decisions / F. R. Hall -- Evaluation of compounds for control of foliar grape phylloxera, Daktulosphaira vitifoliae (Fitch) in Ohio / M. J. McLeod and R. N. Williams -- Marketing Ohio Strawberries / W. T. Rhodus and R. C. Fun

    Fruit crops, 1982: a summary of research

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    Influence of six rootstocks and herbicides on growth, cropping, and fruit quality of Blaxtayman apple trees / David C. Ferree and Robert G. Hill, Jr. -- Tree performance and yield efficiency of several apple cultivars on M9 and M9 interstems / D. C. Ferree -- Chemical induction of lateral shoots on young apple trees / S. C. Myers and D. C. Ferree -- The influence of urea sprays, mulch, and pruning on apple tree decline / G. A. Cahoon and C. W. Donoho, Jr. -- Influence of fireblight and ambrosia beetle on several apple cultivars on M9 and M9 interstems / F. R. Hall, M. A. Ellis, and D. C. Ferree -- A model study of the effect of wind on air sprayer jets / R. D. Fox, D. L. Reichard, and R. D. Brazee -- A comparative study of selected vineyard training and pruning systems for 'Concord' grapevines / G. A. Cahoon -- Effects of selected soil applied herbicides on grapes / Jomo MacDermot and Garth A. Cahoon -- Evaluation of aromatic compounds and virgin females as attractants for rose chafer / Roger N. Williams, Terrence P. McGovern, and Michael Klein -- Botrytis cinerea "gray mold" isolates from strawberry resistant to benlate in Ohio / P. Tanboon-Ek and M. A. Elli

    A mathematical model for breath gas analysis of volatile organic compounds with special emphasis on acetone

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    Recommended standardized procedures for determining exhaled lower respiratory nitric oxide and nasal nitric oxide have been developed by task forces of the European Respiratory Society and the American Thoracic Society. These recommendations have paved the way for the measurement of nitric oxide to become a diagnostic tool for specific clinical applications. It would be desirable to develop similar guidelines for the sampling of other trace gases in exhaled breath, especially volatile organic compounds (VOCs) which reflect ongoing metabolism. The concentrations of water-soluble, blood-borne substances in exhaled breath are influenced by: (i) breathing patterns affecting gas exchange in the conducting airways; (ii) the concentrations in the tracheo-bronchial lining fluid; (iii) the alveolar and systemic concentrations of the compound. The classical Farhi equation takes only the alveolar concentrations into account. Real-time measurements of acetone in end-tidal breath under an ergometer challenge show characteristics which cannot be explained within the Farhi setting. Here we develop a compartment model that reliably captures these profiles and is capable of relating breath to the systemic concentrations of acetone. By comparison with experimental data it is inferred that the major part of variability in breath acetone concentrations (e.g., in response to moderate exercise or altered breathing patterns) can be attributed to airway gas exchange, with minimal changes of the underlying blood and tissue concentrations. Moreover, it is deduced that measured end-tidal breath concentrations of acetone determined during resting conditions and free breathing will be rather poor indicators for endogenous levels. Particularly, the current formulation includes the classical Farhi and the Scheid series inhomogeneity model as special limiting cases.Comment: 38 page
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