127 research outputs found
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The East Midlands: economy a joint response to changing economic circumstances
This document provides an assessment of the regional economy as the UK entered recession in 2008 and sets out how emda, local agencies and Government would work together to tackle the challenges posed by the recession
Overeducation across British regions
This paper analyses levels of over-education and wage returns to education for males across
eleven regions of the UK using Labour Force Survey data. Significant differences are found
in the probability of being over-educated across regions; also, differences are found in the
return to the ‘correct’ level of education in each region, in each case associated with
flexibility of movement between and into particular regions, which determines the ease of job
matching. Furthermore, evidence is found that, after controlling for the level of education
acquired, there exists a premium to the ‘correct’ level of education, which varies across UK
regions
ON THE PERFORMANCE OF NONPARAMETRIC SPECIFICATION TESTS IN REGRESSION MODELS
Some recently developed nonparametric specification tests for regression models are described in a unified way. The common characteristic of these tests is that they are consistent against any alternative hypothesis. The performance of the test statistics is compared by means of Monte Carlo simulations, analysing how heteroskedasticity, number of regressors and bandwidth selection influence the results. The statistics which do not use a bandwidth perform slightly better if the regression model has only one regressor; otherwise, some of the statistics which use a bandwidth behave better if the bandwidth is chosen adequately. These statistics are applied to test the specification of three commonly used Mincer-type wage equations with Uruguayan and Spanish data; all of them are rejected.
Reducing the environmental impact of trials: a comparison of the carbon footprint of the CRASH-1 and CRASH-2 clinical trials
BACKGROUND: All sectors of the economy, including the health research sector, must reduce their carbon emissions. The UK National Institute for Health Research has recently prepared guidelines on how to minimize the carbon footprint of research. We compare the carbon emissions from two international clinical trials in order to identify where emissions reductions can be made. METHODS: We conducted a carbon audit of two clinical trials (the CRASH-1 and CRASH-2 trials), quantifying the carbon dioxide emissions produced over a one-year audit period. Carbon emissions arising from the coordination centre, freight delivery, trial-related travel and commuting were calculated and compared. RESULTS: The total emissions in carbon dioxide equivalents during the one-year audit period were 181.3 tonnes for CRASH-1 and 108.2 tonnes for CRASH-2. In total, CRASH-1 emitted 924.6 tonnes of carbon dioxide equivalents compared with 508.5 tonnes for CRASH-2. The CRASH-1 trial recruited 10,008 patients over 5.1 years, corresponding to 92 kg of carbon dioxide per randomized patient. The CRASH-2 trial recruited 20,211 patients over 4.7 years, corresponding to 25 kg of carbon dioxide per randomized patient. The largest contributor to emissions in CRASH-1 was freight delivery of trial materials (86.0 tonnes, 48% of total emissions), whereas the largest contributor in CRASH-2 was energy use by the trial coordination centre (54.6 tonnes, 30% of total emissions). CONCLUSIONS: Faster patient recruitment in the CRASH-2 trial largely accounted for its greatly increased carbon efficiency in terms of emissions per randomized patient. Lighter trial materials and web-based data entry also contributed to the overall lower carbon emissions in CRASH-2 as compared to CRASH-1. TRIAL REGISTRATION NUMBERS: CRASH-1: ISRCTN74459797CRASH-2: ISRCTN86750102
Reconciling nuclear risk: The impact of the Fukushima accident on comparative preferences for nuclear power in UK electricity generation
Polls conducted in the United Kingdom following the Fukushima nuclear accident (March 2011) indicated a fairly muted and temporary shift in public approval of nuclear power. This study investigated how: (a) comparative preferences for nuclear power in the U nited Kingdom might have been affected by the accident; and (b) how “supporters” of nuclear power reconciled their pro-nuclear attitude in the wake of the disaster. Between-subjects comparisons with a pre-Fukushima sample revealed our post-Fukushima sample to have comparable preferences for nuclear power. Further analysis suggested that “supporters” retained their pro-nuclear stance in response to Fukushima by emphasizing the necessity of nuclear power in the U.K. context. The theoretical, practical and methodological implications for these findings are discussed
Rationale, design and methods of the Study of Work and Pain (SWAP): a cluster randomised controlled trial testing the addition of a vocational advice service to best current primary care for patients with musculoskeletal pain (ISRCTN 52269669)
Background
Musculoskeletal pain is a major contributor to short and long term work absence. Patients
seek care from their general practitioner (GP) and yet GPs often feel ill-equipped to deal with
work issues. Providing a vocational case management service in primary care, to support
patients with musculoskeletal problems to remain at or return to work, is one potential
solution but requires robust evaluation to test clinical and cost-effectiveness.
Methods/Design
This protocol describes a cluster randomised controlled trial, with linked qualitative
interviews, to investigate the effect of introducing a vocational advice service into general
practice, to provide a structured approach to managing work related issues in primary care
patients with musculoskeletal pain who are absent from work or struggling to remain in work.
General practices (n = 6) will be randomised to offer best current care or best current care
plus a vocational advice service. Adults of working age who are absent from or struggling to
remain in work due to a musculoskeletal pain problem will be invited to participate and 330
participants will be recruited. Data collection will be through patient completed
questionnaires at baseline, 4 and 12 months. The primary outcome is self-reported work
absence at 4 months. Incremental cost-utility analysis will be undertaken to calculate the cost
per additional QALY gained and incremental net benefits. A linked interview study will
explore the experiences of the vocational advice service from the perspectives of GPs, nurse
practitioners (NPs), patients and vocational advisors.
Discussion
This paper presents the rationale, design, and methods of the Study of Work And Pain
(SWAP) trial. The results of this trial will provide evidence to inform primary care practice
and guide the development of services to provide support for musculoskeletal pain patients
with work-related issues.
Trial registration
Current Controlled Trials ISRCTN52269669
Advanced reliability analysis of Polymer Electrolyte Membrane Fuel Cells using Petri-Net analysis and fuel cell modelling techniques
This is the author’s version of a work that was accepted for publication in International Journal of Hydrogen Energy. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published at: http://dx.doi.org/10.1016/j.ijhydene.2015.01.154Reliability issues with fuel cells have held back the commercialisation of this
new technology, and as such are required to be studied further. Current
reliability standards for automotive applications require an operational life-
time of 150,000 miles or 5,000 hours. These standards are hard to achieve;
therefore in depth reliability analysis and degradation studies can help allude
towards the key areas of improvement in fuel cell technology to meet these
standards.
Previous Failure Mode and Effect Analysis (FMEA) work has shown
that the multi-component system of a Polymer Electrolyte Membrane Fuel
Cell (PEMFC) is inherently complex. Dependencies exist between multiple
failure modes which discounts Fault Tree Analysis (FTA) as a feasible reliability modelling technique. Therefore, in this study, Petri-Net simulation
and fuel cell modelling techniques have been adopted to develop an accurate
degradation model. Operational parameters such as water content, temperature and current density and their effects on the occurrence of failure modes
can be modelled through this technique. The work will improve previous
fuel cell reliability studies by taking into consideration; operating parameters (water content, temperature), fuel cell voltage based on demand (drive
cycles) and dependencies between failure modes
Classification of beach response to extreme storms
publisher: Elsevier articletitle: Classification of beach response to extreme storms journaltitle: Geomorphology articlelink: http://dx.doi.org/10.1016/j.geomorph.2017.07.022 content_type: article copyright: Crown Copyright © 2017 Published by Elsevier B.V
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