PPAC\u27s Disney Musicals in Schools: A Step to Building Providence Culture

In an educational partnership with the Providence Performing Arts Center (PPAC), students from DEE3999 are working to produce videos that bring Disney musicals to urban schools in Rhode Island. The project encourages students from various majors to brainstorm concepts, film on site, and edit to deliver creative and on-strategy videos to the client. The videos highlight the program and inform parents, teachers, and school districts about the importance of the performing arts in grade schools. The design of PPAC’s Disney Musicals in Schools program gives students in urban Rhode Island school districts the opportunity to learn and perform theatrical pieces, which ultimately contribute to their educational experience. Overall, the videos address the importance of arts in grade schools and the overall contribution Disney Musicals in Schools will have on the culture and community of Providence

Providence Performing Arts Center: Disney Musicals in Schools Program

In the partnership with the Providence Performing Arts Center (PPAC), students from DEE3999 will produce videos for the partner’s objective: to bring Disney Musicals in Schools, the theater program, to urban schools in Rhode Island. The project with PPAC will encourage DEE students to brainstorm concepts, film on-site, and edit to deliver creative and on-strategy videos to the client. The videos will highlight the program and inform parents, teachers, and school districts about the importance of performance arts in grade schools. The design of Disney Musicals in Schools gives students in urban school districts the opportunity to learn and perform theatrical pieces, which ultimately contribute to their educational experience. Overall, the videos for PPAC will address the importance of arts in grade schools and the overall contribution Disney Musicals in Schools will have on the culture and community of Providence

Binding of the human nucleotide excision repair proteins XPA and XPC/HR23B to the 5R-thymine glycol lesion and structure of the cis-(5R,6S) thymine glycol epimer in the 5′-GTgG-3′ sequence: destabilization of two base pairs at the lesion site

The 5R thymine glycol (5R-Tg) DNA lesion exists as a mixture of cis-(5R,6S) and trans-(5R,6R) epimers; these modulate base excision repair. We examine the 7:3 cis-(5R,6S):trans-(5R,6R) mixture of epimers paired opposite adenine in the 5′-GTgG-3′ sequence with regard to nucleotide excision repair. Human XPA recognizes the lesion comparably to the C8-dG acetylaminoflourene (AAF) adduct, whereas XPC/HR23B recognition of Tg is superior. 5R-Tg is processed by the Escherichia coli UvrA and UvrABC proteins less efficiently than the C8-dG AAF adduct. For the cis-(5R, 6S) epimer Tg and A are inserted into the helix, remaining in the Watson–Crick alignment. The Tg N3H imine and A N6 amine protons undergo increased solvent exchange. Stacking between Tg and the 3′-neighbor G•C base pair is disrupted. The solvent accessible surface and T2 relaxation of Tg increases. Molecular dynamics calculations predict that the axial conformation of the Tg CH3 group is favored; propeller twisting of the Tg•A pair and hydrogen bonding between Tg OH6 and the N7 atom of the 3′-neighbor guanine alleviate steric clash with the 5′-neighbor base pair. Tg also destabilizes the 5′-neighbor G•C base pair. This may facilitate flipping both base pairs from the helix, enabling XPC/HR23B recognition prior to recruitment of XPA

The ABC130 barrel module prototyping programme for the ATLAS strip tracker

For the Phase-II Upgrade of the ATLAS Detector, its Inner Detector, consisting of silicon pixel, silicon strip and transition radiation sub-detectors, will be replaced with an all new 100 % silicon tracker, composed of a pixel tracker at inner radii and a strip tracker at outer radii. The future ATLAS strip tracker will include 11,000 silicon sensor modules in the central region (barrel) and 7,000 modules in the forward region (end-caps), which are foreseen to be constructed over a period of 3.5 years. The construction of each module consists of a series of assembly and quality control steps, which were engineered to be identical for all production sites. In order to develop the tooling and procedures for assembly and testing of these modules, two series of major prototyping programs were conducted: an early program using readout chips designed using a 250 nm fabrication process (ABCN-25) and a subsequent program using a follow-up chip set made using 130 nm processing (ABC130 and HCC130 chips). This second generation of readout chips was used for an extensive prototyping program that produced around 100 barrel-type modules and contributed significantly to the development of the final module layout. This paper gives an overview of the components used in ABC130 barrel modules, their assembly procedure and findings resulting from their tests.Comment: 82 pages, 66 figure

Factors Associated with Revision Surgery after Internal Fixation of Hip Fractures

Background: Femoral neck fractures are associated with high rates of revision surgery after management with internal fixation. Using data from the Fixation using Alternative Implants for the Treatment of Hip fractures (FAITH) trial evaluating methods of internal fixation in patients with femoral neck fractures, we investigated associations between baseline and surgical factors and the need for revision surgery to promote healing, relieve pain, treat infection or improve function over 24 months postsurgery. Additionally, we investigated factors associated with (1) hardware removal and (2) implant exchange from cancellous screws (CS) or sliding hip screw (SHS) to total hip arthroplasty, hemiarthroplasty, or another internal fixation device. Methods: We identified 15 potential factors a priori that may be associated with revision surgery, 7 with hardware removal, and 14 with implant exchange. We used multivariable Cox proportional hazards analyses in our investigation. Results: Factors associated with increased risk of revision surgery included: female sex, [hazard ratio (HR) 1.79, 95% confidence interval (CI) 1.25-2.50; P = 0.001], higher body mass index (fo

The Pathway to Independence Inventory: A Validity Study of a Transition Assessment Tool for Postsecondary Students with Disabilities

This study investigated the psychometric properties of the Pathway to Independence Inventory (PII), a new transition assessment tool designed to meet the needs of college-bound students with disabilities who have identified gaps in the areas of adaptive skills, executive functions, and social skills. Analyses examined the factor structure, internal consistency, concurrent validity, and interrater reliability of the instrument as well as differences based on gender identity, disability status, and instrument version (i.e., student report and informant report). The study used an extant dataset of 155 students currently or previously enrolled in a postsecondary support program for students with disabilities. The results of the construct validity analysis indicated tentative evidence of a seven-factor structure of the instrument using subscales as manifest variables and also indicated that the factor structure and loadings hold across the two versions. The results of the reliability and validity analysis indicated acceptable internal consistency, limited evidence of concurrent validity, and no evidence of interrater reliability between students and their informants. Finally, group difference analyses indicated significant differences between instrument version across all scales and indicated significant differences on academic skills based on gender identity and on interpersonal skills based on disability status. Implications for both research and practice are discussed including the need for further replication research on this instrument to confirm these findings and generate additional evidence of its efficacy with college-bound students with disabilities