Wire GEM detector

A wire GEM (WGEM) detector with a gas gap between meshes was constructed. The detector provides the amplification 5x10E5 for the gas mixture of Ar +20% CO2 at atmospheric pressure. As compared with well-known GEM detectors produced by perforation the plastic plate metalized on both sides the WGEM does not suffer from breakdowns between its electrodes and the effect of accumulation of charges on holes walls is absent. As a result the WGEM has high reliability and stability.Comment: Presented at the RD51 Collaboration Meeting, CERN, November 2009, submitted to the Prib. Tech. Expe

RETGEM with polyvinylchloride (PVC) electrodes

This paper presents a new design of the RETGEM (Resistive Electrode Thick GEM) based on electrodes made of a polyvinylchloride material (PVC). Our device can operate with gains of 10E5 as a conventional TGEM at low counting rates and as RPC in the case of high counting rates without of the transit to the violent sparks. The distinct feature of present RETGEM is the absent of the metal coating and lithographic technology for manufacturing of the protective dielectric rms. The electrodes from PVC permit to do the holes by a simple drilling machine. Detectors on a RETGEM basis could be useful in many fields of an application requiring a more cheap manufacturing and safe operation, for example, in a large neutrino experiments, in TPC, RICH systems.Comment: Presented at the RD51 Collaboration Meeting, CERN, November 200

Functional-morphological parallels of the hypothalamo-pituitary-adrenal system response reaction to long-term hypokinesia

The effect of 2 and 4 week hypokinesia regimens on the hypothalamo-pituitary-adrenal system (HPAS) was investigated in 110 inbred mice. Progressive exhaustion and pathological reorganization of the HPAS morphofunctional structures was revealed. On the basis of established facts of interlineary and interspecies differences in the HPAS response, it is suggested that the animal body response reaction to the long term effects of hypokinesia depends largely on its HPAS resistance and the values of this system's defensive adaptation potential

Radio Emission and Particle Acceleration in SN 1993J

The radio light curves of SN 1993J are found to be well fit by a synchrotron spectrum, suppressed by external free-free absorption and synchrotron self-absorption. A standard r^-2 circumstellar medium is assumed, and found to be adequate. The magnetic field and number density of relativistic electrons behind the shock are determined. The strength of the magnetic field argues strongly for turbulent amplification behind the shock. The ratio of the magnetic and thermal energy density behind the shock is ~0.14. Synchrotron and Coulomb cooling dominate the losses of the electrons. The injected electron spectrum has a power law index -2.1, consistent with diffusive shock acceleration, and the number density scales with the thermal electron energy density. The total energy density of the relativistic electrons is, if extrapolated to gamma ~ 1, ~ 5x10^-4 of the thermal energy density. The free-free absorption required is consistent with previous calculations of the circumstellar temperature of SN 1993J, T_e ~ (2-10)x10^5 K. The relative importance of free-free absorption, Razin suppression, and the synchrotron self-absorption effect for other supernovae are briefly discussed. Guidelines for the modeling and interpretation of VLBI observations are given.Comment: accepted for Ap.

Changes in gene DNA methylation and expression networks accompany caste specialization and age-related physiological changes in a social insect

Social insects provide systems for studying epigenetic regulation of phenotypes, particularly with respect to differentiation of reproductive and worker castes, which typically arise from a common genetic background. The role of gene expression in caste specialization has been extensively studied, but the role of DNA methylation remains controversial. Here, we perform well replicated, integrated analyses of DNA methylation and gene expression in brains of an ant (Formica exsecta) with distinct female castes using traditional approaches (tests of differential methylation) combined with a novel approach (analysis of co-expression and co-methylation networks). We found differences in expression and methylation profiles between workers and queens at different life stages, as well as some overlap between DNA methylation and expression at the functional level. Large portions of the transcriptome and methylome are organized into "modules" of genes, some significantly associated with phenotypic traits of castes and developmental stages. Several gene co-expression modules are preserved in co-methylation networks, consistent with possible regulation of caste-specific gene expression by DNA methylation. Surprisingly, brain co-expression modules were highly preserved when compared with a previous study that examined whole-body co-expression patterns in 16 ant species, suggesting that these modules are evolutionarily conserved and for specific functions in various tissues. Altogether, these results suggest that DNA methylation participates in regulation of caste specialization and age-related physiological changes in social insects.Peer reviewe

Semi-Hard Scattering Unraveled from Collective Dynamics by Two-Pion Azimuthal Correlations in 158 A GeV/c Pb + Au Collisions

Elliptic flow and two-particle azimuthal correlations of charged hadrons and high-$p_T$ pions ($p_T>$ 1 GeV/$c$) have been measured close to mid-rapidity in 158A GeV/$c$ Pb+Au collisions by the CERES experiment. Elliptic flow ($v_2$) rises linearly with $p_T$ to a value of about 10% at 2 GeV/$c$. Beyond $p_T\approx$ 1.5 GeV/$c$, the slope decreases considerably, possibly indicating a saturation of $v_2$ at high $p_T$. Two-pion azimuthal anisotropies for $p_T>$ 1.2 GeV/$c$ exceed the elliptic flow values by about 60% in mid-central collisions. These non-flow contributions are attributed to near-side and back-to-back jet-like correlations, the latter exhibiting centrality dependent broadening.Comment: Submitted to Phys. Rev. Letters, 4 pages, 5 figure

Low-mass e+e- pair production in 158 A GeV Pb-Au collisions at the CERN SPS, its dependence on multiplicity and transverse momentum

We report a measurement of low-mass electron pairs observed in 158 GeV/nucleon Pb-Au collisions. The pair yield integrated over the range of invariant masses 0.2 < m < 2.0 GeV is enhanced by a factor of 3.5 +/- 0.4 (stat) +/- 0.9 (syst) over the expectation from neutral meson decays. As observed previously in S-Au collisions, the enhancement is most pronounced in the invariant-mass region 300-700 MeV. For Pb-Au we find evidence for a strong increase of the enhancement with centrality. In addition, we show that the enhancement covers a wide range in transverse momentum, but is largest at the lowest observed pt.Comment: 17 pages, 4 figures, submitted to Phys.Lett.