523 research outputs found

    Parades, parties and pests: contradictions of everyday life in peacekeeping economies

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    Based on research studies conducted in the UN peacekeeping mission in Liberia in 2006, 2012 and 2013, this article argues that peacekeepers’ everyday experiences reflect a series of contradictory identities and performances with regard to nation, work and gender. Peacekeepers straddle paradoxical worlds simultaneously and manage oppositional demands and obligations, although it is often assumed that they inhabit peacekeeping economies in homogenous ways. Importantly, the experiences provide opportunities for peacekeepers to invest in, accumulate and deploy military capital; to consolidate their military identities; and to favourably and tactically position themselves as deserving and useful subjects within the peacekeeping landscape

    Retelling racialized violence, remaking white innocence: the politics of interlocking oppressions in transgender day of remembrance

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    Transgender Day of Remembrance has become a significant political event among those resisting violence against gender-variant persons. Commemorated in more than 250 locations worldwide, this day honors individuals who were killed due to anti-transgender hatred or prejudice. However, by focusing on transphobia as the definitive cause of violence, this ritual potentially obscures the ways in which hierarchies of race, class, and sexuality constitute such acts. Taking the Transgender Day of Remembrance/Remembering Our Dead project as a case study for considering the politics of memorialization, as well as tracing the narrative history of the Fred F. C. Martinez murder case in Colorado, the author argues that deracialized accounts of violence produce seemingly innocent White witnesses who can consume these spectacles of domination without confronting their own complicity in such acts. The author suggests that remembrance practices require critical rethinking if we are to confront violence in more effective ways. Description from publisher's site: http://caliber.ucpress.net/doi/abs/10.1525/srsp.2008.5.1.2

    DESIGN, OPTIMIZATION, DEVELOPMENT AND EVALUATION OF ONCE A DAY CONTROLLED RELEASE FORMULATION OF RIVASTIGMINE TARTARATE

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    Rivastigmine, an Anti-Alzheimer’s drug suffer from a major limitation of sever GI adverse events such as nausea, vomiting, diarrhea, loss of appetite, weight loss and increase dosing frequency [1]. The present work aim at design, optimization and development of rivastigmine once a day controlled release formulation to minimize the above limitation and increase patient’s compliance. Based on the target in-vitro release profile derived from pharmacokinetic simulation [2], a once a day matrix tablet with the simulated dose was developed. The simple direct compression process was followed as a manufacturing process, the percentage of Polymer HPMC K100M, Polyethylene oxide (PEO WSR303) and insoluble excipients microcrystalline cellulose used in the formulation were optimized using 23 full factorial design. The formulations were then evaluated for the physical characteristics of blend, tablets, swelling index, percentage of erosion, drug release and release rate kinetic. The quadratic model was suggested, contour and 3D graphs were generated. The optimized formulation was subjected to stability studies. The final optimized formulation showed a comparative release profile similar to that the desired in-vitro target release profile, which followed zero order release kinetics and a stable formulation.Keywords: Controlled Release Formulation, Rivastigmine Tartarate, Anti-Alzheimer’s drug, HPMC K100M, Polyethylene oxide (PEO WSR303

    The initial impact of the COVID-19 pandemic on the diagnosis of new cancers at a large pathology laboratory in the public health sector, Western Cape Province, South Africa

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    Background. The COVID-19 pandemic has disrupted cancer diagnostic services. A decline in the number of new cancers being diagnosed over a relatively short term implies a delay in diagnosis and subsequent treatment. This delay is expected to have a negative effect on cancerrelated morbidity and mortality. The impact of the pandemic on the number of new cancer diagnoses in our setting is unknown.Objectives. To assess the impact of COVID-19 on the number of new cancers diagnosed at our institution in the first 3 months following the implementation of lockdown restrictions, by focusing on common non-cutaneous cancers.Methods. A retrospective laboratory-based audit was performed at a large anatomical pathology laboratory in Western Cape Province, South Africa. The numbers of new diagnoses for six common cancers (breast, prostate, cervix, large bowel, oesophagus and stomach) from 1 April 2020 to 30 June 2020 were compared with the corresponding period in 2019.Results. Histopathological diagnoses for the six cancers combined decreased by 193 (–36.3%), from 532 new cases in the 2019 study period to 339 in the corresponding period in 2020. Substantial declines were seen for prostate (–58.2%), oesophageal (–44.1%), breast (–32.9%), gastric (–32.6%) and colorectal cancer (–29.2%). The smallest decline was seen in cervical cancer (–7%). New breast cancers diagnosed by cytopathology declined by 61.1%.Conclusions. The first wave of the COVID-19 pandemic and the associated response resulted in a substantial decline in the number of new cancer diagnoses, implying a delay in diagnosis. Cancer-related morbidity and mortality is expected to rise as a result, with the greatest increase in mortality expected from breast and colorectal cancer

    Disciplining dissent: multicultural policy and the silencing of Arab-Canadians

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    This article examines two cases of state funding cuts to the most prominent and active Arab community organisations operating in Canada, the Canadian Arab Federation and Palestine House. It contextualises the cuts within broader ‘crisis of multiculturalism’ debates imbued with anti-Arab/anti-Muslim racism and the silencing of Palestine advocacy efforts; arguing that the shift to a neoliberal multiculturalism, emptied of anti-racist politics, along with the construction of national identities around a set of western ‘core values’ has advanced a marginalising politics that demarcates a ‘civilisational’ border which excludes Arabs, Muslims, and by extension Palestine solidarity. Curtailing freedom of expression, partly through funding cuts, thus becomes a key mechanism for disciplining dissent in racialised communities

    Transcendence over Diversity: black women in the academy

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    Universities, like many major public institutions have embraced the notion of ‘diversity’ virtually uncritically- it is seen as a moral ‘good in itself’. But what happens to those who come to represent ‘diversity’- the black and minority ethnic groups targeted to increase the institutions thirst for global markets and aversion to accusations of institutional racism? Drawing on existing literature which analyses the process of marginalization in higher education, this paper explores the individual costs to black and female academic staff regardless of the discourse on diversity. However despite the exclusion of staff, black and minority ethnic women are also entering higher education in relatively large numbers as students. Such ‘grassroots’ educational urgency transcends the dominant discourse on diversity and challenges presumptions inherent in top down initiatives such as ‘widening participation’. Such a collective movement from the bottom up shows the importance of understanding black female agency when unpacking the complex dynamics of gendered and racialised exclusion. Black women’s desire for education and learning makes possible a reclaiming of higher education from creeping instrumentalism and reinstates it as a radical site of resistance and refutation
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