51 research outputs found
MENTAL HEALTH CRISIS IN PREGNANT WOMEN DURING CURRENT COVID-19 PANDEMIC
- Author
- Publication venue
- Publication date
- 01/01/2020
- Field of study
Performance evaluation of convolutional neural network for hand gesture recognition using EMG
- Author
- Publication venue
- 'MDPI AG'
- Publication date
- 02/03/2020
- Field of study
peer reviewedElectromyography (EMG) is a measure of electrical activity generated by the contraction of muscles. Non-invasive surface EMG (sEMG)-based pattern recognition methods have shown the potential for upper limb prosthesis control. However, it is still insufficient for natural control. Recent advancements in deep learning have shown tremendous progress in biosignal processing. Multiple architectures have been proposed yielding high accuracies (>95%) for offline analysis, yet the delay caused due to optimization of the system remains a challenge for its real-time application. From this arises a need for optimized deep learning architecture based on fine-tuned hyper-parameters. Although the chance of achieving convergence is random, however, it is important to observe that the performance gain made is significant enough to justify extra computation. In this study, the convolutional neural network (CNN) was implemented to decode hand gestures from the sEMG data recorded from 18 subjects to investigate the effect of hyper-parameters on each hand gesture. Results showed that the learning rate set to either 0.0001 or 0.001 with 80-100 epochs significantly outperformed (p < 0.05) other considerations. In addition, it was observed that regardless of network configuration some motions (close hand, flex hand, extend the hand and fine grip) performed better (83.7% ± 13.5%, 71.2% ± 20.2%, 82.6% ± 13.9% and 74.6% ± 15%, respectively) throughout the course of study. So, a robust and stable myoelectric control can be designed on the basis of the best performing hand motions. With improved recognition and uniform gain in performance, the deep learning-based approach has the potential to be a more robust alternative to traditional machine learning algorithms
Human Papillomavirus Genotype Distribution in Invasive Cervical Cancer in Pakistan
- Author
- Publication venue
- 'MDPI AG'
- Publication date
- 25/07/2018
- Field of study
Few studies have assessed the burden of human papillomavirus (HPV) infection in Pakistan. We aim to provide specific information on HPV-type distribution in invasive cervical cancer (ICC) in the country. A total of 280 formalin-fixed paraffin-embedded tissue blocks were consecutively selected from Shaukat Khanum Memorial Cancer Hospital and Research Centre (Lahore, Pakistan). HPV-DNA was detected by SPF10 broad-spectrum PCR followed by DNA enzyme immunoassay and genotyping by LiPA25. HPV-DNA prevalence was 87.5% (95%CI: 83.0-91.1), with 96.1% of cases histologically classified as squamous cell carcinoma. Most of the HPV-DNA positive cases presented single infections (95.9%). HPV16 was the most common type followed by HPV18 and 45. Among HPV-DNA positive, a significantly higher contribution of HPV16/18 was detected in Pakistan (78.4%; 72.7-83.3), compared to Asia (71.6%; 69.9-73.4) and worldwide (70.8%; 69.9-71.8) and a lower contribution of HPVs31/33/45/52/58 (11.1%; 7.9-15.7 vs. 19.8%; 18.3-21.3 and 18.5%; 17.7-19.3). HPV18 or HPV45 positive ICC cases were significantly younger than cases infected by HPV16 (mean age: 43.3, 44.4, 50.5 years, respectively). A routine cervical cancer screening and HPV vaccination program does not yet exist in Pakistan; however, the country could benefit from national integrated efforts for cervical cancer prevention and control. Calculated estimations based on our results show that current HPV vaccine could potentially prevent new ICC cases
A digital score of tumour-associated stroma infiltrating lymphocytes predicts survival in head and neck squamous cell carcinoma
- Author
- Publication venue
- 'Center for Open Science'
- Publication date
- 16/04/2021
- Field of study
Concept mapping and conceptual change texts: a constructivist approach to address the misconceptions in nanoscale science and technology
- Author
- Publication venue
- Frontiers Media S.A.
- Publication date
- 01/02/2024
- Field of study
Nanoscale Science and Technology (NST) is a rapidly evolving field with profound implications for various industries and our everyday lives. However, misconceptions among learners can hinder their ability to grasp the fundamental concepts of NST, thereby impeding their potential contributions to this advancing domain. Concept maps (CM) and conceptual change texts (CCT) are graphical and written representations of knowledge that enable learners to visualize relationships between concepts and assess the coherence of their understanding. In this pursuit, we engage with the concept of rehabilitation for misconceptions, viewing the learning process as a transformative journey akin to cognitive rehabilitation. Through this CM-CCT constructivist approach, learners are encouraged to engage in critical reflection, self-questioning, and peer discussions, which facilitate the identification of misconceptions. Moreover, CM-CCT provide a structured framework for presenting accurate information about NST, offering a clear depiction of the hierarchical and interconnected nature of nanoscale phenomena. The aim of this study was to evaluate the effectiveness of CM-CCT in correcting the misconceptions of undergraduate university students regarding nanotechnology and the taxonomy of nonmaterial. Prior to the implementation of the CM-CCT, an assessment of pre-existing knowledge of the students was performed through the structure of the observed learning outcomes (SOLO) taxonomy. A quasi-experimental research design was carried out. A total of 70 undergraduate university students, divided into two intact groups, were cross-examined for the study. Further, before and after the instructional tools, an achievement test based on nanotechnology and classification of nonmaterial was conducted, covering all six cognitive domains of the Bloom taxonomy of educational objectives. Data analysis revealed that the instructional tools based on constructivist approach had a statistically significant impact on students for elimination of their misconceptions about nanotechnology, nano science and classification of nonmaterial
Burnout among surgeons before and during the SARS-CoV-2 pandemic: an international survey
- Author
- Abbas Ahmed Hosam Eldin Hasan
- Abbas Ghanem
- Abbas Hazem
- Abbatini Francesca
- Abdalbakheet Duaa
- Abdallah Emad
- Abdelazim Tarek
- Abdelaziz Nabil Yassin Tammam
- Abdelglil Momen
- Abdelhalim Ahmed
- Abdelhalim Mostafa Mohammed
- Abdelhamid Ahmed
- Abdelhamid Mohamed Sayed
- Abdelkhalik Morsi Mohamed Morsi
- Abdellatif Ahmed
- Abdelmageed Mohammed Elkassaby
- Abdelmaksoud Mohamed
- Abdelmohsen Ahmed
- Abdelmomen Ahmed Ezzat Elghrieb
- Abdelmoneim Ibrahim Tharwat Mohamed
- Abdelmonem Mohamed Ahmed
- Abdelmotaleb Hussien Ali
- Abdelrafee Ahmed
- Abdelrasheed Sayed
- Abdelsayed Emad Fahim
- Abdo Nael
- Abdulatef Shehab Ahmed Ali
- Abdullah Alqahtani Ali
- Abdulrahman Chadi
- Abdur-Rahman Lukman
- Abduraboh Abdullah Fayez
- Abed Ali Ibrahim Eldawy
- Abiodun Azeez Lateef
- Abiyere Henry
- Aboelmagid Hamdy Haggag Ebrahim
- Abolnasr Khaled Samir
- Abosi-Appeadu Kessewa
- Abouelnagah Galal
- Abozeid Ahmad Mahmoud
- Abozeid Mahmoud
- Abualkhair Wael
- Abualnaja Yousra
- Abualsel Abdulmenem
- Abuosba Abdelrahman
- Abusalem Osama
- Abusiam Wael
- Abutalib Raid Abdullah
- Abuzeid Mohamed Mostafa
- Addari Giulio
- Adebowale Yusuf
- Adejumo Adeyinka
- Adel Mohammed
- Adeoluwa Ojajuni
- Adeyeye Ademola
- Adly Ramy Magdy
- Adorisio Ottavio
- Agbonrofo Peter
- Agrawal Abhishek
- Ahmad Farooq
- Ahmad Misbahu Haruna
- Ahmad Mustafa
- Ahmad Sufian
- Ahmad Suhaib
- Ahmed Abeer Abdul Hameed
- Ahmed Arooj
- Ahmed Emad Ali
- Ahmed Hassan
- Ahmed Mohamed
- Ahmed Mostafa Mahmoud
- Aitali Abdelmounaim
- Akeel Nouf
- Akhtar Khalid
- Akin Furkan Atakan
- Akinmade Akinola
- Al Eisa Abdulmohsen
- Al Hassn Ibrahim
- Al Naeb Mohamed
- Al Turki Neamat Ahmed Ali
- Al-Bahrani Ahmed
- Al-Kubati Waheeb
- Al-Masari Hayder Makki
- Al-Sadery Humood
- Alaa Mohammed
- Alabbas Haytham
- Alafghani Haitham
- Alarabi Rayan
- Alawadhi Abdulbari Mohammed
- Alawady Mohammed
- Alawfi Homoud
- Alazzam Saleh
- Albadry Ali Almahdy Ali
- Albahooth Khalid
- Albalawi Ibrahim Altedlawi
- Albeshri Khalid A.
- Aleksandr Ogoreltsev
- Alfalah Haitham
- Algatanesh Nassib
- Alghamdi Faisal Saleh
- Alghamdi Saleh
- Alghuliga Abdullah
- Alhamdany Arkan Shubber
- Alharbi Abdulhamid
- Alhazmi Barrag
- Alhazmi Waleed
- Alhedaithy Alhanouf
- Alhendawey Moaaz
- Alhussaini Mohammed Khalid
- Alhussien Fade Ahmed
- Ali Ali Sayed
- Ali Bandar Idrees A.
- Ali Doaa
- Ali Mahmoud
- Ali Mohamed Anwar Abdel Razik
- Ali Muhammad Zulfiqar
- Ali Shabeer
- Ali Syed Muhammad
- Aliyu Yakubu
- Aljathlany Yousef
- Aljawhari Adel Ali
- Alkhalegy Ayman
- Alkhayat Ali
- Alkhayat Mohammed Amer
- Allaeys Mathias
- Almaghrabi Alhassan Hesham
- Almasri Mahmoud
- Almulhim Abdulrhman
- Alnabarawi Mahmoud
- Alnahas Yousef
- Alnashar Ahmed
- Alnoqaidan Emad
- Alomieri Adil
- Alotaibi Abdullah
- Alotaibi Abdulrahman
- Alotaibi Abdulrahman
- Alowairdhi Tumadher
- Alqarni Ahmed
- Alqasaby Abdallah
- Alqudaihi Heba
- Alrashidi Yousef
- Alsallum Ofays
- Alsawat Salem
- Alshabi Yaser Ahmad
- Alshehari Mohammed Mohammed Hasan
- Alshukr Sarah
- Alsuwaimel Munir A.
- Althobaiti Majid
- Althumali Abdullah
- Altomare Donato F.
- Alvarez Gallesio José Maria
- Alwan Ahmed
- Alwusaibie Ahmed
- Alyami Mohammad
- Alzahrani Khalid H.
- Alzahrani Saud
- Alzamanan Mahdi
- Alzamel Heythem
- Amal Benzakour
- Amary Mohamed Mokhtar
- Amen Mohamed Mohsen
- Amer Nasser Mohammed
- Amir Mohammed
- Amr Wesam
- Andrea Chierici
- Andrea Police
- Andriola Valeria
- Angrisani Marco
- Angulo Victor Manuel Pinto
- Antonio D’Alessandro
- Anwer Mariyah
- Aoun Rany
- Arbutina Dragana
- Archid Rami
- Aremu Isiaka
- Argenio Giulio
- Arnold Marion
- Arnouse Mohamed Mohamed Hamdy
- Asar Khalid Mohammad Ibrahim
- Ashimov Erkin
- Ashraf Tamer
- Asif Muhammad
- Aslam Mohammad
- Ateeb Mujammad
- Atef Gehad
- Atici Semra Demirli
- Attia Ahmed Mohamed
- Ayoub Larissa
- Azer Mina
- Aziz Mina
- Aziz Muhammad Akram Abdul
- Ba Mamadou
- Bacher Annica
- Bafaraj Ahmed
- Bagaglini Giulia
- Balla Andrea
- Barbary Hesham
- Barberis Andrea
- Barbon Carlotta
- Basendowah Mohammed
- Bashah Moataz M.
- Bashir Umar
- Bashlachev Andrey
- Bassuni Majid
- Bàmbina Fabrizio
- Bellato Vittoria
- Belli Andrea
- Bensaad Ahmed
- Berchtold Valeria
- Bernante Paolo
- Bertels Laurie
- Beshir Hatem
- Bhatt Nikita
- Bogdan Stoica
- Bonci Eduard-Alexandru
- Borasi Andrea
- Botros Ibram
- Botteri Emanuele
- Bouchrika Amal
- Boukorou Garyfallia
- Brahmachari Swagata
- Bruzzaniti Placido
- Calik Bulent
- Calvo Mikel Prieto
- Campagnaro Tommaso
- Campanelli Michela
- Campennì Paola
- Canfora Alfonso
- Capizzi Vita
- Carrano Francesco Maria
- Castaldi Antonio
- Cavallaro Giuseppe
- Chacón Mario Franco
- Charalabopoulos Alexandros
- Cherfa Harieche Abdennour Abderahim
- Chiarella Vito
- Chipaila Jackson
- Cianci Pasquale
- Cillara Nicola
- Cirillo Bruno
- Ciubotaru Cezar
- Colás-Ruiz Enrique
- Colleoni Ramiro
- Colombo Francesco
- Coniglio Denise
- Costanzo Federico
- Cuk Vladica
- Curtis Nathan
- Dagorno Claire
- Daibes Adel Goda Hussein
- Danilov Michail
- Dare Julius Kolajo
- Daudi Irfan
- Davies Justin
- Dawdi Salahaldeen
- De Falco Nadia
- De Fatico GSerena
- De La Hermosa Alicia Ruiz
- De Lucia Francesca
- De Sousa Xavier
- Del Muslim Ka
- Demeester Steve
- Depuydt Martijn
- Dere Ümit Akın
- Derinov Aleksandr
- Di Bartolomeo Alessandro
- Di Carlo Sara
- Di Lorenzo Nicola
- Di Martino Marcello
- Di Saverio Salomone
- Diamantopoulou Angela
- Díaz Andrés Vega
- Díaz Jeancarlos J. Trujillo
- Doerner Johannes
- Dogjani Agron
- Don Cristine
- Duran Erik Efrain Sosa
- Durayb Norah
- Dursun Ayberk
- Dziakova Jana
- Echevarria Miguel Jose Pinto
- Edassy Mohammed El
- Efetov Sergey
- Eke Grace
- El-Hussuna Alaa
- El-Wakeel Ayman
- Elalfy Khaled
- Elbahrawy Aly
- Elbatal Amira Alsayed Abdelhai
- Eldeeb Ahmed
- Eldemery Mohamed
- Eldesouki Mohammed Nabil
- Eldesouky Omnia
- Eleshra Ahmed
- Elfeki Hossam
- Elgaly Maher Elesawi Kamel
- Elgamal Hesham
- Elganash Abdelazim
- Elgazar Amr
- Elgazar Elsayed Aly
- Elgendy Hesham
- Elghadban Hosam
- Elhafez Raheem El-Gohary Abd
- Elhattab Ahmad
- Elhawary Ahmed Adel
- Elkafoury Ahmed
- Elkased Ahmed Farag
- Elkatt Mahmoud Mohamed
- Elkhouly Ahmed G.
- Elmesery Mohamed
- Elmetwally Ashraf S.
- Elmoghazy Mohamed Ibrahim
- Elnaghi Hisham
- Elnakash Ahmed Mostafa
- Elnemr Islam
- Elnour Ahmed Abd Elbaset Elsayed Abu
- Elrefai Mohamad
- Elsaied Adham
- Elsanhoury Kareem
- Elsanosi Abdelrhman Azhari Mohammed
- Elsayed Mohamed Abdelmoneim
- Elsayed Mohamed Ahmed Abdelhalim Ahmed
- Elseberbihy John Rezk Hanna
- Elshaer Ahmed Mohammed
- Elshazli Mostafa
- Elsheik Ahmad
- Elsheik Ahmed
- Elsherbiny Osama
- Elshikh Essam
- Elsorogy Mohamed
- Elvira Tartaglia
- Elzayady Hany M.
- Elzayat Ibrahim
- Elzeftawy Shady Ahmed
- Emile Sameh Hany
- Enad Farazdaq
- Epifani Angelo Gabriele
- Eral Burak
- Ezz Ahmed
- Fadel Bashir A.
- Fahiem Andrew
- Fakhr Ibrahim
- Falaschi Federica
- Familiari Pietro
- Farag Mohamed
- Farid Ahmed Mohammed
- Farid Mohamed
- Farouk Mohamed
- Farouk Nehal
- Fathy Mohammad
- Fatima Tauseef
- Fawzy Ahmed
- Faye Papa Mamadou
- Fayed Mohamed Abdelaziz Mohamed Abdalla M
- Fazli Mohammad Rafi
- Felix Marcos José Serrato
- Ferrara Francesco
- Ferrario Luca
- Ferri Lorenzo
- Fieturi Nura Ahmed
- Fikry Mohamed
- Fiore Antonio
- Flores Manuel SSalas
- Foppa Caterina
- Fouad Amgad
- Franceschilli Marzia
- Fransvea Pietro
- Frasson Matteo
- Frauenfelder Claire
- Frazzetta Giuseppe
- Freitas Carla
- Frigerio Isabella
- Frontali Alice
- Gaarour Osama
- Gabr Mohamed A.
- Gad Hamada
- Galala Ahmed
- Gallo Gaetano
- Gamal Ehab
- Gamal Sameh
- Ganau Mario
- Garino Mauro
- Garmanovs Tatiana
- Garoufalia Zoe
- Garreffa Emanuele
- Gazia Carlo
- Gehwolf Philipp
- Gendy Samuel Elkess Morcos
- George Ihediwa
- Ghabisha Saif Ali
- Ghafoor Tariq
- Ghanem Ahmed
- Gharbia Mohamed
- Ghazala Mohamed Jomma
- Ghonim Mostafa
- Ghunaim Mohammed
- Giani Alessandro
- Giardino Alessandro
- Giarratano Gabriella
- Giuffrida Maria Carmela
- Giugliano Marco
- Golea Smain
- Gomez Caroina Gonzalez
- Gondal Zafar
- Gonzales Erick Ivan Huaman
- Gorin David
- Gots Alexander
- Grappelli Virgilio Michael Ambrosi
- Guaitoli Eleonora
- Guerci Claudio
- Guerrero José Eaazim Flores
- Guida Anna
- Gulcu Baris
- Gurung Binay
- Haddad Feras
- Hadi Sabah Anwar
- Hamdi Salah
- Hamed Esmael Ali
- Hamed Hosam
- Hamed Mohamed Korayem Fattouh
- Hammad Muhammed Alaa Moukhtar
- Hamza Ahmed
- Hanif Muhammad Amir
- Hasani Ariola
- Hassan Mohamed Ali Gad
- Hassan Mohamed Salah Eldin
- Hassan Redan
- Hatm Mohamed
- Haydal Ashraf
- Hegazy Mostafa
- Hejazi Soha
- Helal Mohamed Alaa Abdelmoez
- Helmy Ahmed Hazem I.
- Hemidan Ahmed Gamal Abouelfetouh Ibrahim
- Henes Mohsen Michael
- Hesham Hosai Todd
- Hijazi Bilal Ahmed
- Hilling Denise
- Holubar Stefan D.
- Hussain Marwah
- Hussein Abdinafic Mohamud
- Ibrahim Ahmed
- Ibrahim Hamed
- Ibrahim Yaser
- Ibrahim Yassin
- Ignatov Ivan
- Ilkul Jh.
- Inam Aatif
- Inama Marco
- Ioan Tanase
- Ioannidis Argyrios
- Iossa Angelo
- Ippoliti Simona
- Isaiah Isaac A.
- Isci Sevim
- Islam S. M. Nazmul
- Ismail Ahmed Mahmoud Ahmed
- Izzo Giuliano
- Jain Amita
- Jallad Fadi Sami
- Jaman Ismail
- Jameel Muhammad Khurram
- Japhet Ntezamizero
- Jarboa Lutfi
- Jarvis Bennie L.
- Jasso Manuel Meza
- Javed Ayesha
- Jawad Fassi Fihri Mohamed
- Jeffery James
- Jolayemi Edward
- Jooma Uzair
- Juloski Jovan
- Junaid Sheikh
- Kaldarov Ayrat
- Kandel Mohamed Mosaad
- Karbovnichaya Elena
- Kassem Amr
- Kateb Abdullah
- Kaur Mandeep
- Kaya Tayfun
- Kazachenko Ekaterina
- Kazim Shuiab
- Kerawala Asad Ali
- Kewulere Raji Taofiq
- Khadwardi Faisal
- Khafagy Tamer
- Khafagy Wael
- Khalaf Mohsen George
- Khalil Medhat M. H. A.
- Khan Irfan Jan
- Khan Roaa Ghazi
- Khare Ritu
- Khashshan Sohib Mohammed Mohammed
- Khawar Mahwish
- Khoj Mohammed
- Khokhar Muhammad Imran
- Khudhayr Essa
- Khuller Somyaa
- Kilinc Gizem
- Kırmızı Yasemin
- Kiselev Michail
- Kitsenko Yury
- Klein Mads Falk
- Koc Mehmet Ali
- Koirala Dinesh Prasad
- Kostakis Ioannis D.
- Kress Melissa
- Kropshofer Stephan
- Kumar Sanjeev
- La Torre Filippo
- Laina Juan Luis Blas
- Lakshmi Harish Neelamraju
- Landaluce-Olavarria Aitor
- Lapolla Pierfrancesco
- Larbi Noureddine
- Lateef Nawras Falah
- Lathan Sanaz
- Lawal Bashir
- Lederhuber Hans
- Lelpo Benedettao
- Leo Cosimo Alex
- Leventoğlu Sezai
- Lewis Sophia
- Liakakos Theodore
- Light Alexander
- Lisi Giorgio
- Litta Francesco
- Lotfy Ahmad
- Loukil Issam
- Luc Jessica G. Y.
- Lule Herman
- Lund Jon
- Lutfi Basma Waseem
- Machairas Nikolaos
- Madbouly Khaled
- Madhuri Thumuluru Kavitha
- Maffioli Anna
- Maghrebi Houcine
- Mahadel Osama Abdel Salam
- Majeed Mudassar
- Majid Haroon Javaid
- Makasarwala Murtaza
- Malek Amgad Nashaat Abdel
- Malibary Nadim
- Maliki-Alaoui Mohamed
- Manetti Andrea
- Mangiameli Giuseppe
- Mansour Khaled Yousery Ibrahim
- Marafante Chiara
- Marano Alessandra
- Marcos Alberto
- Mariani Aurora
- Mariani Nicolò Maria
- Mariateresa Grasso
- Marino Marco V.
- Marra Angelo Alessandro
- Marsanic Patrizia
- Martin Linda W.
- Martin-Perez Beatriz
- Martinelli Fabio
- Marzouk Ahmed Msm
- Marzouk Khalid
- Matarangolo Antonio
- Maurizi Angela
- Mazingi Dennis
- Mbatani Nomonde
- Mbiine Ronald
- Mccaul Jeannie
- Mcnamara Deborah
- Medkova Iuliia
- Mehr Asma
- Mehraj Asif
- Mejdane Abdelhadi
- Menna Maria Paola
- Metwally Mohamed
- Mikhael Marolla Maher Eskander
- Mikrish Amir
- Milad Nader
- Milana Flavio
- Milford Karen
- Milic Ljiljana
- Millan Monica
- Mingoli Andrea
- Minoldo Javier
- Mirza Mohammad Amin
- Mitul Ashrarur Rahman
- Moeslein Gabriela
- Mohamed Mohamed Mohamed Adel
- Mohamed Anwar Yahya A.
- Mohamed Omnia Y.
- Mohammad Mohammad Aminu
- Mohammed Khalid Fathelrahman Bakier
- Mohammed Mahfoudh
- Mohammed Mahmoud M.
- Mohammed Mohammed Mustafa Hassan
- Mohammed Ouazni
- Mohmmed Mona Mhmoud
- Molena Daniela
- Montalbán Beatriz Cros
- Monti Alessio
- Montuori Mauro
- Mora-Guzmán Ismael
- More Vinal
- Morini Andrea
- Moustafa Mohammad Montaser Hassan
- Mpaili Eustratia
- Mubarak Ashraf Abdelazeem Mohamed
- Mudawi Ishag M.
- Muhammad Aneeqah Din
- Muresan Mihai-Stefan
- Mussa Haidar Aal
- Musthafa Shameel
- Nabeeh Mohamed Adel
- Nabil Tamer
- Nabwana Ambrose
- Nadeem Munawar
- Nadeem Uqba
- Nageeb Ashraf
- Nageeb Ramy Mikhael
- Najm Ghadah
- Nakazwe Mildred
- Nasef Hazem
- Nasir Muhammad
- Ndong Abdourahmane
- Negida Ahmed
- Negoi Ionut
- Nekhala Islam
- Ng Hwei Jene
- Ng Jen Siang
- Niaz Khurram
- Nimir Nessrein
- Ninkovic Marijana
- Nittala Rigved
- Njau Aidan
- Njokanma Iloba Gabriel
- Njoroge Githu
- Novikova Anastasia
- Obadiel Yasser Abdurabo
- Obure Ralph Ombati
- Ocklind Miranda E. K.
- Odion Clement
- Okunlola Abiodun Idowu
- Oludara Mobolaji Adewale
- Oluwasuyi Ige
- Oluyomi Ayodele Samuel
- Omar Mohamed I.
- Omar Tilioua
- Oosthuizen Pj
- Orecchia Luca
- Orlando Francesco
- Osman Khalid Abdalla Abdelgadir
- Osman Luqman
- Ouadii Mouaqit
- Oyedepo Charles Olajide
- Paci Marco
- Pagano Gianluca
- Pakula Andrea M.
- Palkhi Yusuf
- Pandey Diwakar
- Papadopoulos Georgios
- Parello Angelo
- Parente Alessandro
- Parida Lalit
- Pata Francesco
- Peediyakkal Saidalavi Padinhare
- Pellino Gianluca
- Perra Teresa
- Petagna Lorenzo
- Pérez-Bertólez Sonia
- Picciariello Arcangelo
- Pignatelli Marcello Filograna
- Pinotti Enrico
- Pio Luca
- Pirovano Riccardo
- Pirozzi Brunella
- Pitoni Ludovica
- Pohl Linda
- Ponholzer Florian
- Popoola Ademola
- Porcu Alberto
- Portela Carlos Antonio Sanchez
- Pouwels Sjaak
- Prodromidou Anastasia
- Puerto Puerto Alejandro
- Puzenko Dmitriy
- Quesada Matias
- Qurashi Kamran
- Qureshi Ahmad Uzair
- Rabea Mohamed
- Rachid Mohamed Ghassane
- Rao Satish
- Raptis Dimitri
- Rashid Arshad
- Rashid Shahid
- Ratto Carlo
- Rayamajhi Shreya
- Raza Muhammad Asif
- Rea Lo Dico
- Regal Samer
- Rho Maurizio
- Rihan Eslam
- Rimonda Roberto
- Rizk Tarek Taher
- Robles Eloy Morasen
- Rodimov Sergey
- Romic Ivan
- Roscio Francesco
- Rottoli Matteo
- Rubio-Perez Ines
- Ruiz Luis Angel Garcia
- Saad Ahmad
- Saadeldin Abdelhalim
- Saber Wael
- Sabet Khaled
- Sacchi Matteo
- Saeed Muhammad Ahmad
- Sahnan Kapil
- Said Khalid Babieker
- Saklani Avanish
- Sakr Ahmad
- Saleh Amr
- Salem Eman Abdalla Mohamed
- Salem Mohamed Abouelmagd
- Salim Mohammed Said Mahmoud
- Salim Omer El Faroug H.
- Salim Sami
- Sallam Ibrahim
- Salman Usama
- Samadov Elgun
- Samaha Mahmoud Yahia
- Sanad Aly
- Sanad Mohammed
- Santos Esther Garcia
- Santurro Letizia
- Sapienza Paolo
- Sarhan Fetoh Alaaeldin Fetoh
- Sarmah Panchali
- Sasia Diego
- Sauri Fozan
- Sayouh Mohammad
- Sbaih Mohammed
- Scafa Anthony Kevin
- Schuldes Alejandro Daniel Lira
- Sciaudone Guido
- Sebelik Merry
- Seiam Moham
- Selvaggi Francesco
- Sembawa Hatem A.
- Semilan Anmar
- Senent-Boza Ana
- Senra Fatima
- Sergeevich Kochetkov Viktor
- Shafique Muhammad Salman
- Shah Rahmat Ullah
- Shah Shahzad Alam
- Shaheen Abelnasser
- Shahein Mostafa
- Shahin Yasser
- Shaikh Abdul Razaque
- Shaker George Samir Habib
- Shalaby Mostafa
- Shams Maher
- Sharaf Hesham
- Sharafeldin Hatem Abdelrahman Ahmed
- Sharma Meenakshi
- Shawer Sami
- Shawer Sherif
- Shehata Mina
- Shemes Ayman
- Sherbiny Kareem El
- Sherif Ahmed Elshawadfy
- Shetiwy Mosab
- Shittu Asimiyu Adekunle
- Shomoye El-Zaki
- Sibiany Abdulrahman
- Siboe Mark M. W.
- Sidorova Lyudmila
- Sileri Pierpaolo
- Silva Jesús
- Simioni Andrea
- Sindy Abdullah
- Singh Baljit
- Siragusa Leandro
- Situ Oladele
- Skandalakis Georgios P.
- Slavchev Mihail
- Sleilati Fadi
- Sobh Mohamed Ramadan
- Sofan Mostafa
- Soggiu Fiammetta
- Sokmen Selman
- Soliman Ahmed
- Spinelli Antonino
- Spolverato Gaya
- Ssenono Kavuma Daniel
- Stanislav Berelavichus
- Stavrou George
- Stijns Jasper
- Styliani Vasileiadou
- Subramanian Sivaraman
- Suliman Omar AAbu
- Tabasi Hani
- Tagg Gamal Hassan El
- Tairab Elsanousi Ibrahim Sabir
- Taki-Eldin Ahmed
- Tallon-Aguilar Luis
- Taman Mohamed
- Tamburrini Alessandro Paolo
- Tamini Nicolò
- Tanda Cinzia
- Tarabay Ahmed
- Tashkandi Wail
- Tashkandi Waleed
- Tecchio Piero
- Tejedoe Patricia
- Tesik Philip
- Testa Valentina
- Thakrar Dixa
- Thein Nyan
- Tohamy Aley Eldin
- Toma Omar
- Tong Kin Seng
- Torky Radwan Abdelsabour
- Towfigh Shirin
- Troci Albert
- Tropeano Francesca Paola
- Tsounaki Efthymia
- Tuncer Korhan
- Turrado-Rodríguez Víctor
- Uccelli Matteo
- Ugarte-Sierra Bakarne
- Uggeri Fabio
- Uraiqat Ahmad
- Uranitsch Stefan
- Uslu Gülberk
- Valente Marina
- Valery Nekoval
- Van Daele Elke
- Van Praet Charles
- Van Ramshorst Gabrielle H.
- Vanlander Aude
- Vanommeslaeghe Hanne
- Varma Gopala Pillay
- Vázquez-Melero Alba
- Vella Ivan
- Veltri Marco
- Venturelli Paolina
- Vikrantmr Sharma
- Villwock Jennifer
- Visconti Diego
- Vishwakarma Kushagra
- Vosloo Susan
- W Njoroge P.
- Waleed Aasma
- Wali Zubair
- Waqar Shahzad Hussain
- Warusavitarne Janindra
- Waseem Talat
- Wexner Steven
- Wuraola Funmilola Olanike
- Yacir El Alami
- Yakar Fatih
- Yanaga Katsuhiko
- Yassin Nouf
- Yassine Wassim Abou
- Yeşilyurt Değercan
- Yildiz Alp
- Yousef Yousef Mohamed
- Youssef Mohamed
- Youssef Youssef Abdel Aziz
- Yves Van Nieuwenhove
- Zafar Noman
- Zahra Tarek
- Zaidi Mariam
- Zaieem Mohammad
- Zakaria Hazem M.
- Zakharenko Alexander
- Zancana Giuseppa
- Zentar Aziz
- Zese Monica
- Zewar Karem Shahin Mohamed
- Zidan Ahmed Azmy
- Zigiotto Daniele
- Zubayraeva Albina
- Zuhdy Mohammad
- Publication venue
- Publication date
- 01/01/2024
- Field of study
Background: SARS-CoV-2 pandemic has had many significant impacts within the surgical realm, and surgeons have been obligated to reconsider almost every aspect of daily clinical practice. Methods: This is a cross-sectional study reported in compliance with the CHERRIES guidelines and conducted through an online platform from June 14th to July 15th, 2020. The primary outcome was the burden of burnout during the pandemic indicated by the validated Shirom-Melamed Burnout Measure. Results: Nine hundred fifty-four surgeons completed the survey. The median length of practice was 10 years; 78.2% included were male with a median age of 37 years old, 39.5% were consultants, 68.9% were general surgeons, and 55.7% were affiliated with an academic institution. Overall, there was a significant increase in the mean burnout score during the pandemic; longer years of practice and older age were significantly associated with less burnout. There were significant reductions in the median number of outpatient visits, operated cases, on-call hours, emergency visits, and research work, so, 48.2% of respondents felt that the training resources were insufficient. The majority (81.3%) of respondents reported that their hospitals were included in the management of COVID-19, 66.5% felt their roles had been minimized; 41% were asked to assist in non-surgical medical practices, and 37.6% of respondents were included in COVID-19 management. Conclusions: There was a significant burnout among trainees. Almost all aspects of clinical and research activities were affected with a significant reduction in the volume of research, outpatient clinic visits, surgical procedures, on-call hours, and emergency cases hindering the training. Trial registration: The study was registered on clicaltrials.gov "NCT04433286" on 16/06/2020
Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study
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- A. Adam M.
- A. Nassar M.
- A. Nemer A.
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- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2022
- Field of study
Background Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide.Methods A multimethods analysis was performed as part of the GlobalSurg 3 study-a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital.Findings Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3.85 [95% CI 2.58-5.75]; p<0.0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63.0% vs 82.7%; OR 0.35 [0.23-0.53]; p<0.0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer.Interpretation Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised
Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries
- Author
- Abad-Motos Ane
- Abbas Ahmed M.
- Abbas Mostafa
- Abbasi Mujeeb
- Abbott Tom
- Abd Karim Muhammad Fairuz Shah
- Abdalaal Ibrahim
- Abdel-Galil Khalid
- Abdelemam Rania
- Abdelgawad Abdalrahman
- Abdelkarim Maryam
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- Hameed Bm Zeeshan
- Hamid Hytham K. S.
- Hamida Baha Ben
- Hamill James
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- Kealey Joshua
- Kebede Ephrem
- Kedwany Ahmed
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- Kent Alistair J
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- Lyra Humberto Fenner
- Mabood Waleed
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- Mahečić Tina Tomić
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- Martins Ana
- Martins Claudia Pinto
- Martins Paulo N.
- Martínez Daniel Fernández
- Martínez Eunate Ganuza
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- Matthews Emily
- Mauriello Claudio
- Maurus Christine
- Mayer Horacio F.
- Mayo-Yáñez Miguel
- Mazzarella Gennaro
- Mbodi Langanani
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- McLeish Bethan
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- Meara John G.
- Meead Adullah
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- Mengesha Mengistu G.
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- Nacion Aeris Jane D.
- Nadi Khaldoun
- Naegele Felix
- Naga Hani
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- Nankivell Paul
- Naranjo Eddy P. Lincango
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- Nassar Mahmoud A.
- Nasser Sara
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- Newman Samuel
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- Ntalouka Maria P.
- Ntirenganya Faustin
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- Oktseloglou Vlasios
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- Olori Samson
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- Onyemaechi Ndubuisi
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- Oshodi Yusuf
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- Punjabi Prakash P
- Puri Ajay
- Purich Kieran
- Pérez Beatriz Gómez
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- Rauf Umme Habiba Abdul
- Raurich-Leandro Jordi
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- Ravindra Raevin
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- Richard H.
- Rickard Jennifer
- Rincón Natalia Andrea Rivera
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- Rodriguez-Lopez Mario
- Rodríguez Lorena Varela
- Rokohl Alexander Christopher
- Roland Christina L
- Rolinger Jens
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- Samadov Elgun
- Saman Pradeep I.H.D.
- Samara Athina
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- Sambhwani Sharan
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- Vaughan-Shaw Peter G.
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- Vizzielli Giuseppe
- Vohra Lubna
- Vokshi Ismail
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- Vázquez Gil
- Vázquez Irene Ortega
- Vǎcǎraşu Andrei Bogdan
- Wade Ryckie
- Wafi Omar
- Wagner Gabriela
- Wallis Christopher
- Wanjara Samuel
- Waqar Shahzad Hussain
- Warden Claire
- Warner Christian
- Wasim D.
- Wason Shaun
- Wasserman Isaac
- Watcyn-Jones Tom
- Waterson Ben
- Watson David
- Watson Matthew
- Weber Clemens
- Wheatstone P.
- Wheeler James
- Wheldon Luke
- White Michelle
- White Stuart
- White William
- Wickramasinghe Dakshitha
- Widmer Lukas Werner
- Wiedemann Dominik
- Wiesinger Clemens Georg
- Wijekoon Naveen
- Wijenayake Wasantha
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- Wijeysundera Duminda
- Wiles Matthew
- Wilkin Richard
- Wilkins Alex
- Wilkins James
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- Williams Omolara Modupe
- Williams Shekinah
- Windsor John
- Winnand Philipp
- Wittmann Maria
- Wolde Amanuel
- Wolfenden John W. D.
- Wong Benjamin Ngie Xiong
- Wong Enoch
- Wong Evan G.
- Wong George Kwok Chu
- Wong Ho Ying Flora
- Wong Kai Yuen
- Wormald Justin
- Wright Deborah
- Wright Joshua
- Wu Fiona
- Wurm Markus
- Xenaki Sofia
- Yadev Ip
- Yahaya Ahmad Shuib
- Yakubu Mustapha
- Yang Wah
- Yanik Özge
- Yanowsky-Reyes Guillermo
- Yassin Abubaker
- Yates Elizabeth
- Yebes Alvaro
- Yenli Edwin Mwintiereh Ta-Ang
- Yeoh Tien
- Yeung Justin
- Yiallourou Anneza
- Yigit Banu
- Yildirim Asif
- Yim Guang
- Yiu Andrew
- Yonekura Hiroshi
- Yotsov Tsanko
- Younis Muhammad Umar
- Yunus Alif
- Yusefi Hossein
- Zabaleta Jon
- Zabkiewicz Catheriner
- Zaccaria Giulia
- Zacharia Bincy
- Zafar Syed Nabeel
- Zago Mauro
- Zaheen Zakia
- Zahid Zahra
- Zaimis Tilemachos
- Zakaria Andee Dzulkarnaen
- Zambon Martina
- Zamora Lindsey
- Zampogna Biagio
- Zancana Giuseppa
- Zani Augusto
- Zanin Luca
- Zanini Nicola
- Zapardiel Ignacio
- Zapata Carlos Shiraishi
- Zarif Pierre
- Zaránd Attila
- Zehnder Philipp
- Zenger Serkan
- Zenha Horácio
- Zhu Michael Z. L.
- Ziemann Sebastian
- Zimak Danijela Mrazovac
- Zimak Zoran
- Zivkovic Dragana
- Zizzo Maurizio
- Zucker Benjamin
- Zwain Yasir
- Zyskowski Michael
- Ávila Clara Castro
- Älgå Andreas
- Çakici Mehmet Çaǧlar
- Çelik Enes
- Çelik Meryem Nur
- Özçay Necdet
- Şevik Hüsnü
- Šantak Goran
- Šimko Kristián
- Žatecký Jan
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2023
- Field of study
Abstract
Background
Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres.
Methods
This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries.
Results
In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia.
Conclusion
This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries
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- Aali Amirali
- Ababneh Hazim S
- Abate Yohannes Habtegiorgis
- Abbafati Cristiana
- Abbasgholizadeh Rouzbeh
- Abbasi-Kangevari Mohsen
- Abbasian Mohammadreza
- Abbastabar Hedayat
- Abd ElHafeez Samar
- Abd-Elsalam Sherief
- Abdelmasseh Michael
- Abdelwahab Ahmed
- Abdollahi Mohammad
- Abdollahifar Mohammad-Amin
- Abdoun Meriem
- Abdulah Deldar Morad
- Abdullahi Auwal
- Abebe Mesfin
- Abebe Samrawit Shawel
- Abedi Aidin
- Abegaz Kedir Hussein
- Abhilash E S
- Abidi Hassan
- Abiodun Olumide
- Aboagye Richard Gyan
- Abolhassani Hassan
- Abolmaali Meysam
- Abouzid Mohamed
- Aboye Girma Beressa
- Abreu Lucas Guimarães
- Abrha Woldu Aberhe
- Abtahi Dariush
- Abu Rumeileh Samir
- Abu-Gharbieh Eman
- Abu-Rmeileh Niveen ME
- Abu-Zaid Ahmed
- Abualruz Hasan
- Abubakar Bilyaminu
- Aburuz Salahdein
- Accrombessi Manfred Mario Kokou
- Adal Tadele Girum
- Adamu Abdu A
- Addo Isaac Yeboah
- Addolorato Giovanni
- Adebiyi Akindele Olupelumi
- Adekanmbi Victor
- Adepoju Abiola Victor
- Adetunji Charles Oluwaseun
- Adetunji Juliana Bunmi
- Adeyeoluwa Temitayo Esther
- Adeyinka Daniel Adedayo
- Adeyomoye Olorunsola Israel
- Admass Biruk Adie Adie
- Adnani Qorinah Estiningtyas Sakilah
- Adra Saryia
- Afolabi Aanuoluwapo Adeyimika
- Afzal Muhammad Sohail
- Afzal Saira
- Agampodi Suneth Buddhika
- Agasthi Pradyumna
- Aggarwal Manik
- Aghamiri Shahin
- Agide Feleke Doyore
- Agodi Antonella
- Agrawal Anurag
- Agyemang-Duah Williams
- Ahinkorah Bright Opoku
- Ahmad Aqeel
- Ahmad Danish
- Ahmad Firdos
- Ahmad Muayyad M
- Ahmad Sajjad
- Ahmad Shahzaib
- Ahmad Tauseef
- Ahmadi Keivan
- Ahmadzade Amir Mahmoud
- Ahmed Ali
- Ahmed Ayman
- Ahmed Haroon
- Ahmed Luai A
- Ahmed Mehrunnisha Sharif
- Ahmed Meqdad Saleh
- Ahmed Muktar Beshir
- Ahmed Syed Anees
- Ajami Marjan
- Aji Budi
- Akara Essona Matatom
- Akbarialiabad Hossein
- Akinosoglou Karolina
- Akinyemiju Tomi
- Akkaif Mohammed Ahmed
- Akyirem Samuel
- Al Hamad Hanadi
- Al Hasan Syed Mahfuz
- Al-Aly Ziyad
- Al-amer Rasmieh Mustafa
- Al-Azzam Sayer
- Al-Gheethi Adel Ali Saeed
- Al-Hanawi Mohammed Khaled
- Al-Marwani Sabah
- Al-Maweri Sadeq Ali Ali
- Al-Mekhlafi Hesham M
- Al-Omari Basem
- Al-Sabah Salman Khalifah
- Al-Tawfiq Jaffar A
- Al-Worafi Yaser Mohammed
- Alahdab Fares
- Alalalmeh Samer O
- Alalwan Tariq A
- Alam Khurshid
- Alam Manjurul
- Alam Noore
- Alanezi Fahad Mashhour
- Alanzi Turki M
- Albakri Almaza
- Albashtawy Mohammed
- AlBataineh Mohammad T
- Alcalde-Rabanal Jacqueline Elizabeth
- Aldawsari Khalifah A
- Aldhaleei Wafa A
- Aldridge Robert W
- Alema Haileselasie Berhane
- Alemayohu Mulubirhan Assefa
- Alemi Sharifullah
- Alemu Yihun Mulugeta
- Alhabib Khalid F
- Alhalaiqa Fadwa Alhalaiqa Naji
- Ali Abid
- Ali Amjad
- Ali Liaqat
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- Ali Rafat
- Ali Shahid
- Ali Syed Shujait Shujait
- Alicandro Gianfranco
- Alif Sheikh Mohammad
- Alikhani Reyhaneh
- Alimohamadi Yousef
- Aliyi Ahmednur Adem
- Aljasir Mohammad A M
- Aljunid Syed Mohamed
- Alla François
- Allebeck Peter
- Almazan Joseph Uy
- Almidani Louay
- Almidani Omar
- Alomari Mahmoud A
- Alonso Jordi
- Alqahtani Jaber S
- Alqalyoobi Shehabaldin
- Alqutaibi Ahmed Yaseen
- Altaany Zaid
- Altaf Awais
- Altirkawi Khalid A
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- Alvis-Guzman Nelson
- Alwafi Hassan
- Aly Hany
- Aly Safwat
- Alzoubi Karem H
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- Amare Azmeraw T
- Amegbor Prince M
- Ameyaw Edward Kwabena
- Amin Tarek Tawfik
- Amindarolzarbi Alireza
- Amiri Sohrab
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- Amusa Ganiyu Adeniyi
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- Anderlini Deanna
- Anderson David B
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- Angus Colin
- Anil Abhishek
- Anil Sneha
- Anoushiravani Amir
- Ansari Hossein
- Ansari-Moghaddam Alireza
- Ansariadi Ansariadi
- Antony Catherine M
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- Anwer Razique
- Anyasodor Anayochukwu Edward
- Aqeel Muhammad
- Arab Juan Pablo
- Arabloo Jalal
- Arafat Mosab
- Aravkin Aleksandr Y
- Areda Demelash
- Aremu Abdulfatai
- Aremu Olatunde
- Ariffin Hany
- Arkew Mesay
- Armocida Benedetta
- Arndt Michael Benjamin
- Arooj Mahwish
- Artamonov Anton A
- Arulappan Judie
- Aruleba Raphael Taiwo
- Arumugam Ashokan
- Asaad Malke
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- Ayatollahi Haleh
- Ayuso-Mateos Jose L
- Ayyoubzadeh Seyed Mohammad
- Azadnajafabad Sina
- Azevedo Rui M S
- Azzam Ahmed Y
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- Bhagavathula Akshaya Srikanth
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- Bhardwaj Nikha
- Bhardwaj Pankaj
- Bhardwaj Prarthna V
- Bhargava Ashish
- Bhaskar Sonu
- Bhat Vivek
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- Bhatti Jasvinder Singh
- Bhatti Manpreet S
- Bhatti Rajbir
- Bhutta Zulfiqar A
- Bikbov Boris
- Bishai Jessica Devin
- Bisignano Catherine
- Bisulli Francesca
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- Biswas Bijit
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- Bitra Veera R
- Bjørge Tone
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- Bodolica Virginia
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- Narasimha Swamy Sreenivas
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- Vinayak Manish
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- Wu Xinsheng
- Wu Zenghong
- Xia Juan
- Xiao Hong
- Xie Yang
- Xu Suowen
- Xu Wang-Dong
- Xu Xiaoyue
- Xu Yvonne Yiru
- Yadollahpour Ali
- Yamagishi Kazumasa
- Yang Danting
- Yang Lin
- Yano Yuichiro
- Yao Yao
- Yaribeygi Habib
- Ye Pengpeng
- Yehualashet Sisay Shewasinad
- Yesiltepe Metin
- Yesuf Subah Abderehim
- Yezli Saber
- Yi Siyan
- Yigezu Amanuel
- Yip Paul
- Yismaw Malede Berihun
- Yismaw Yazachew
- Yiğit Arzu
- Yiğit Vahit
- Yon Dong Keon
- Yonemoto Naohiro
- Yoon Seok-Jun
- You Yuyi
- Younis Mustafa Z
- Yousefi Zabihollah
- Yu Chuanhua
- Yu Yong
- Yuh Faith H
- Zadey Siddhesh
- Zadnik Vesna
- Zafari Nima
- Zakham Fathiah
- Zaki Nazar
- Zaman Sojib Bin
- Zamora Nelson
- Zand Ramin
- Zangiabadian Moein
- Zar Heather J
- Zare Iman
- Zarrintan Armin
- Zeariya Mohammed G M
- Zeinali Zahra
- Zhang Haijun
- Zhang Jianrong
- Zhang Jingya
- Zhang Liqun
- Zhang Yunquan
- Zhang Zhi-Jiang
- Zhao Hanqing
- Zhong Chenwen
- Zhou Juexiao
- Zhu Bin
- Zhu Lei
- Ziafati Makan
- Zielińska Magdalena
- Zitoun Osama A
- Zoladl Mohammad
- Zou Zhiyong
- Zuhlke Liesl J
- Zumla Alimuddin
- Zweck Elric
- Zyoud Samer H
- Ärnlöv Johan
- Šekerija Mario
- Publication venue
- Elsevier
- Publication date
- 03/04/2024
- Field of study
BACKGROUND Regular, detailed reporting on population health by underlying cause of death is fundamental for public health decision making. Cause-specific estimates of mortality and the subsequent effects on life expectancy worldwide are valuable metrics to gauge progress in reducing mortality rates. These estimates are particularly important following large-scale mortality spikes, such as the COVID-19 pandemic. When systematically analysed, mortality rates and life expectancy allow comparisons of the consequences of causes of death globally and over time, providing a nuanced understanding of the effect of these causes on global populations. METHODS The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 cause-of-death analysis estimated mortality and years of life lost (YLLs) from 288 causes of death by age-sex-location-year in 204 countries and territories and 811 subnational locations for each year from 1990 until 2021. The analysis used 56 604 data sources, including data from vital registration and verbal autopsy as well as surveys, censuses, surveillance systems, and cancer registries, among others. As with previous GBD rounds, cause-specific death rates for most causes were estimated using the Cause of Death Ensemble model-a modelling tool developed for GBD to assess the out-of-sample predictive validity of different statistical models and covariate permutations and combine those results to produce cause-specific mortality estimates-with alternative strategies adapted to model causes with insufficient data, substantial changes in reporting over the study period, or unusual epidemiology. YLLs were computed as the product of the number of deaths for each cause-age-sex-location-year and the standard life expectancy at each age. As part of the modelling process, uncertainty intervals (UIs) were generated using the 2·5th and 97·5th percentiles from a 1000-draw distribution for each metric. We decomposed life expectancy by cause of death, location, and year to show cause-specific effects on life expectancy from 1990 to 2021. We also used the coefficient of variation and the fraction of population affected by 90% of deaths to highlight concentrations of mortality. Findings are reported in counts and age-standardised rates. Methodological improvements for cause-of-death estimates in GBD 2021 include the expansion of under-5-years age group to include four new age groups, enhanced methods to account for stochastic variation of sparse data, and the inclusion of COVID-19 and other pandemic-related mortality-which includes excess mortality associated with the pandemic, excluding COVID-19, lower respiratory infections, measles, malaria, and pertussis. For this analysis, 199 new country-years of vital registration cause-of-death data, 5 country-years of surveillance data, 21 country-years of verbal autopsy data, and 94 country-years of other data types were added to those used in previous GBD rounds. FINDINGS The leading causes of age-standardised deaths globally were the same in 2019 as they were in 1990; in descending order, these were, ischaemic heart disease, stroke, chronic obstructive pulmonary disease, and lower respiratory infections. In 2021, however, COVID-19 replaced stroke as the second-leading age-standardised cause of death, with 94·0 deaths (95% UI 89·2-100·0) per 100 000 population. The COVID-19 pandemic shifted the rankings of the leading five causes, lowering stroke to the third-leading and chronic obstructive pulmonary disease to the fourth-leading position. In 2021, the highest age-standardised death rates from COVID-19 occurred in sub-Saharan Africa (271·0 deaths [250·1-290·7] per 100 000 population) and Latin America and the Caribbean (195·4 deaths [182·1-211·4] per 100 000 population). The lowest age-standardised death rates from COVID-19 were in the high-income super-region (48·1 deaths [47·4-48·8] per 100 000 population) and southeast Asia, east Asia, and Oceania (23·2 deaths [16·3-37·2] per 100 000 population). Globally, life expectancy steadily improved between 1990 and 2019 for 18 of the 22 investigated causes. Decomposition of global and regional life expectancy showed the positive effect that reductions in deaths from enteric infections, lower respiratory infections, stroke, and neonatal deaths, among others have contributed to improved survival over the study period. However, a net reduction of 1·6 years occurred in global life expectancy between 2019 and 2021, primarily due to increased death rates from COVID-19 and other pandemic-related mortality. Life expectancy was highly variable between super-regions over the study period, with southeast Asia, east Asia, and Oceania gaining 8·3 years (6·7-9·9) overall, while having the smallest reduction in life expectancy due to COVID-19 (0·4 years). The largest reduction in life expectancy due to COVID-19 occurred in Latin America and the Caribbean (3·6 years). Additionally, 53 of the 288 causes of death were highly concentrated in locations with less than 50% of the global population as of 2021, and these causes of death became progressively more concentrated since 1990, when only 44 causes showed this pattern. The concentration phenomenon is discussed heuristically with respect to enteric and lower respiratory infections, malaria, HIV/AIDS, neonatal disorders, tuberculosis, and measles. INTERPRETATION Long-standing gains in life expectancy and reductions in many of the leading causes of death have been disrupted by the COVID-19 pandemic, the adverse effects of which were spread unevenly among populations. Despite the pandemic, there has been continued progress in combatting several notable causes of death, leading to improved global life expectancy over the study period. Each of the seven GBD super-regions showed an overall improvement from 1990 and 2021, obscuring the negative effect in the years of the pandemic. Additionally, our findings regarding regional variation in causes of death driving increases in life expectancy hold clear policy utility. Analyses of shifting mortality trends reveal that several causes, once widespread globally, are now increasingly concentrated geographically. These changes in mortality concentration, alongside further investigation of changing risks, interventions, and relevant policy, present an important opportunity to deepen our understanding of mortality-reduction strategies. Examining patterns in mortality concentration might reveal areas where successful public health interventions have been implemented. Translating these successes to locations where certain causes of death remain entrenched can inform policies that work to improve life expectancy for people everywhere. FUNDING Bill & Melinda Gates Foundation
Electrode materials for fuel cells
- Publication venue
- 'Elsevier BV'
- Publication date
- 13/01/2020
- Field of study
- …