Experience-based co-design toolkit : Un outil pour l’engagement des communautés dans la gestion de la crise sanitaire du COVID-19

La pandémie de Covid-19, et les résistances aux mesures qui ont émergé au fil du temps, ont démontré l’importance d’impliquer les populations concernées dans la réponse à la crise. Les sciences sociales avaient déjà mis en lumière la nécessité d’une telle implication dans le cadre d’épidémies précédentes comme celles d’Ebola de 2014 et 2016. Dans ce contexte, la communauté des anthropologues a été véritablement impliquée dans la mise en place de la réponse de santé globale aux épidémies en tant que « traducteur·trices culturel·les (cultural brokers) », s’engageant avec les communautés concernées. Pourtant, quand le virus du SARS-CoV-2 a commencé à circuler en Europe, l’importance de l’engagement des communautés concernées semble avoir été minimisée, notamment en Suisse. Dans le but de pouvoir y remédier, nous avons développé le projet SocioImplement - Experience-based co-design Covid-19 recommendations : a tool for communities’ engagement in public health crises, financé dans le cadre du Programme National de Recherche (PNR) 78 – Covid 19. Il s’agit d’un projet collaboratif, réalisé dans le canton de Vaud, en Suisse, qui visait à co-construire avec les acteur·trices concerné·es des recommandations de gestion de crise sur la base de leurs expériences et réalités de terrain. Pour ce faire, nous avons mobilisé la méthode de l’experience-based co-design. Développée initialement dans le milieu des soins, nous l’avons transposée ici à un contexte de santé publique afin de tester ce dispositif de façon innovante. Ce toolkit documente la mise en place du projet avec pour objectif de rendre compte de cette expérience et des apprentissages qui en ont été tirés. En rendant accessible ce dispositif à d’autres chercheur∙euses ou acteur∙trices du système de santé, il vise à leur permettre de s’en emparer pour promouvoir et développer les recherches participatives, collaboratives et communautaires en santé. Chaque étape adaptée du processus sera décrite, ainsi que les limitations et bénéfices liés à la mise en place d’un tel projet

First assessment of geophysical sensitivities from spaceborne Galileo and BeiDou GNSS-Reflectometry data collected by the UK TechDemoSat-1 Mission

The UK’s TechDemoSat-1 (TDS-1), launched 2014, has demonstrated the use of global positioning system (GPS) signals for monitoring ocean winds and sea ice. Here it is shown, for the first time, that Galileo and BeiDou signals detected by TDS-1 show similar promise. TDS-1 made seven raw data collections, recovering returns from Galileo and BeiDou, between November 2015 and March 2019. The retrieved open ocean delay Doppler maps (DDMs) are similar to those from GPS. Over sea ice, the Galileo DDMs show a distinctive triple peak. Analysis, adapted from that for GPS DDMs, gives Galileo’s signal-to-noise ratio (SNR), which is found to be inversely sensitive to wind speed, as for GPS. A Galileo track transiting from open ocean to sea ice shows a strong instantaneous SNR response. These results demonstrate the potential of future spaceborne constellations of GNSS-R (global navigation satellite system–reflectometry) instruments for exploiting signals from multiple systems: GPS, Galileo, and BeiDou

Scouting for Climate Variable with Small Satellites

HydroGNSS is a small satellite mission under the new ESA Scout programme tapping into NewSpace, within ESA’s FutureEO programme. The mission will use an innovative GNSS-Reflectometry instrument to collect parameters related to the Essential Climate Variables (ECVs): soil moisture, inundation, freeze/thaw, biomass, ocean wind speed and sea ice extent. GNSS-Reflectometry is a type of bistatic radar utilizing abundant GNSS signals as signals of opportunity, empowering small satellites to provide measurement quality associated with larger satellites. The HydroGNSS instrument introduces novel measurements compared to its predecessors on UKSA TechDemoSat-1 and NASA CYGNSS missions. These include: the acquisition of Galileo(E1) reflections, and firsts such as dual- polarization, complex ‘coherent channel’ (amplitude/phase) and second frequency (L5/E5a) acquisitions. These measurements enable HydroGNSS to innovate the L2 products, e.g. improving the ground resolution and soil moisture measurement, as dual-polarized reflections allow the discrimination of vegetation effects from soil moisture. HydroGNSS will: ● Complement and potentially gap fill other missions sensing soil moisture e.g. ESA’s SMOS and NASA’s SMAP missions. ● Complement ESA’s Biomass mission addressing coverage restrictions over Europe, North and Central America. ● Expand GNSS-Reflectometry techniques. ● Lay the foundations for a future constellation capable of offering continuity in high spatial-temporal resolution observations of the Earth’s weather and climate

Crustal structure of the carpathian-pannonian region from ambient noise tomography

We use ambient noise tomography to investigate the crust and uppermost mantle structure beneath the Carpathian-Pannonian region of Central Europe. Over 7500 Rayleigh wave empirical Green's functions are derived from interstation cross-correlations of vertical component ambient seismic noise recordings (2005-2011) using a temporary network of 54 stations deployed during the South Carpathian Project (2009-2011), 56 temporary stations deployed in the Carpathian Basins Project (2005-2007) and 100 permanent and regional broad-band stations. Rayleigh wave group velocity dispersion curves (4-40 s) are determined using the multiple-filter analysis technique. Group velocity maps are computed on a grid of 0.2° × 0.2° from a non-linear 2-D tomographic inversion using the subspace method. We then inverted the group velocity maps for the 3-D shear wave velocity structure of the crust and uppermost mantle beneath the region. Our shear wave velocity model provides a uniquely complete and relatively high-resolution view of the crustal structure in the Carpathian-Pannonian region, which in general is validated by comparison with previous studies using other methods to probe the crustal structure. At shallow depths (30 km are relatively fast, presumably related to shallowing of the Moho consequent on the extensional history of the Pannonian region

Organic residue analysis of Egyptian votive mummies and their research potential

YesVast numbers of votive mummies were produced in Egypt during the Late Pharaonic, Ptolemaic, and Roman periods. Although millions remain in situ, many were removed and have ultimately entered museum collections around the world. There they have often languished as uncomfortable reminders of antiquarian practices with little information available to enhance their value as artefacts worthy of conservation or display. A multi-disciplinary research project, based at the University of Manchester, is currently redressing these issues. One recent aspect of this work has been the characterization of natural products employed in the mummification of votive bundles. Using gas chromatography–mass spectrometry and the well-established biomarker approach, analysis of 24 samples from 17 mummy bundles has demonstrated the presence of oils/fats, natural waxes, petroleum products, resinous exudates, and essential oils. These results confirm the range of organic materials employed in embalming and augment our understanding of the treatment of votives. In this first systematic initiative of its kind, initial findings point to possible trends in body treatment practices in relation to chronology, geography, and changes in ideology which will be investigated as the study progresses. Detailed knowledge of the substances used on individual bundles has also served to enhance their value as display items and aid in their conservation.RCB is supported by a PhD studentship from the Art and Humanities Research Council (43019R00209). L.M. and S.A.W. are supported by a Leverhulme Trust Research Project Award (RPG-2013-143)

Three-dimensional velocity structure of the northern Hikurangi margin, Raukumara, New Zealand: Implications for the growth of continental crust by subduction erosion and tectonic underplating

Traveltimes between shots from nine marine seismic reflection lines and nine onshore recorders were used to construct a 3-D P wave velocity model of the northern Hikurangi subduction margin, New Zealand. From north to south between Raukumara Basin and Raukumara Peninsula, the Moho of the overriding plate increases in depth from 17 to similar to 35 km. Low seismic P wave velocities of 3.5-5.0 km/s are localized within a similar to 10 km thick prism in the lower crust of the overriding plate immediately updip of the intersection between the subduction thrust and Moho and beneath the topographic crest of East Cape Ridge and the Raukumara Range. Southward, this region of low seismic velocities and surface uplift increases in distance from the trench as the thickness of the crust in the overriding plate increases. We interpret this low-velocity volume to be underplated sedimentary rocks and crustal materials that were tectonically eroded by subduction beneath the trench slope. The buoyancy and low strength of these subducted materials are proposed to assist the escape from a subduction channel near the base of the crust and drive local rock uplift. In the middle crust, our observations of very low velocity suggest high fluid-filled porosities of 12%-18%, and the implied buoyancy anomaly may enhance underplating. At greater depths the process is driven by the contrast between upper crustal quartz-feldspar mineralogy and the denser diabase or olivine-rich lithologies of the lower crust and mantle. We estimate a rate of lower crustal underplating at the northern Hikurangi margin of 20 +/- 7 km(3) Ma(-1) km(-1) since 22 Ma. We suggest that underplating provides an efficient means of accreting subducted sediment and tectonically eroded material to the lower crust and that the flux of forearc crustal rocks into the mantle at subduction zones may be systematically overestimated

Trafficking of Hepatitis C Virus Core Protein during Virus Particle Assembly

Hepatitis C virus (HCV) core protein is directed to the surface of lipid droplets (LD), a step that is essential for infectious virus production. However, the process by which core is recruited from LD into nascent virus particles is not well understood. To investigate the kinetics of core trafficking, we developed methods to image functional core protein in live, virus-producing cells. During the peak of virus assembly, core formed polarized caps on large, immotile LDs, adjacent to putative sites of assembly. In addition, LD-independent, motile puncta of core were found to traffic along microtubules. Importantly, core was recruited from LDs into these puncta, and interaction between the viral NS2 and NS3-4A proteins was essential for this recruitment process. These data reveal new aspects of core trafficking and identify a novel role for viral nonstructural proteins in virus particle assembly