Pengaruh Kepemimpinan, Pembagian Kerja dan Kompensasi terhadap Kinerja Karyawan pada PT. Air Manado

Sumber daya manusia (SDM) merupakan faktor sentral dalam suatu organisasi. Apapun bentuk dan tujuannya, suatu organisasi didirikan berdasarkan visi untuk kepentingan bersama, dan dalam pelaksanaan misinya dikelola oleh manusia. Tanpa adanya tenaga kerja atau karyawan yang berkualitas, tujuan organisasi sulit untuk tercapai dengan baik. Untuk mencapai tujuan, sebuah organisasi harus didukung oleh sumber daya yang berkualitas baik dari berwujud material, modal maupun manusia. Penelitian ini bertujuan untuk mengetahui pengaruh Kepemimpinan, Pembagian Kerja dan Kompensasi terhadap kinerja karyawan.Populasi penelitian adalah seluruh karyawan PT Air Manado yang berjumlah 254 orang. Sampel yang digunakan adalah semua populasi yang ada. Dengan teknik yang digunakan yaitu Analisis Regresi Berganda, penelitian ini menunjukkan hasil bahwa: Kepemimpinan, Pembagian Kerja, dan Kompensasi secara bersama dan parsial berpengaruh positif dan signifikan terhadap kinerja karyawan. Direksi PT Air Manado sebaiknya meningkatkan kinerja karyawan agar pelayanan dapat menjadi efektif dan efisien. Kata kunci: kepemimpinan, pembagian kerja, kompensasi, kinerj

Probing the Rotational Velocity of Galactic WO Stars with Spectropolarimetry

Oxygen sequence Wolf-Rayet stars (WO) are thought to be the final evolution phase of some high-mass stars, as such they may be the progenitors of Type Ic SNe as well as potential progenitors of broad-lined Ic and long gamma-ray bursts. We present the first spectropolarimetric observations of the Galactic WO stars WR93b and WR102 obtained with FORS1 on the Very Large Telescope. We find no sign of a line effect, which could be expected if these stars were rapid rotators. We also place constraints on the amplitude of a potentially undetected line effect. This allows us to derive upper limits on the possible intrinsic continuum polarization and find Pcont \u3c 0.077 per cent and Pcont \u3c 0.057 per cent for WR93b and WR102, respectively. Furthermore, we derive upper limits on the rotation of our WO stars by considering our results in the context of the wind compression effect. We estimate that for an edge-on case the rotational velocity of WR93b is vrot \u3c 324 km s−1 while for WR102 vrot \u3c 234 km s−1. These correspond to values of vrot/vcrit \u3c 19 per cent and j) \u3c 18.0 cm2 s−1 for WR93b and 2 s−1 for WR102. The upper limits found on vrot/vcrit and log(j) for our WO stars are therefore similar to the estimates calculated for Galactic Wolf-Rayet (WR) stars that do show a line effect. Therefore, although the presence of a line effect in a single WR star is indicative of fast rotation, the absence of a line effect does not rule out significant rotation, even when considering the edge-on scenario

Geochemical indices allow estimation of heavy metal background concentration in soils

Defining background concentrations for heavy metals in soils is essential for recognizing and managing soil pollution. However, background concentrations of metals in soils can vary naturally by several orders of magnitude. Moreover, many soils have also been subject to unquantifiable anthropogenic inputs of metals, in some cases, for centuries. Hence determination of heavy metal background concentrations in soils has to date been fraught with difficulty. Here we demonstrate that there are associations between the background heavy metal and Fe or Mn contents in soils which appear to be consistent for seven important heavy metals of environmental concern. The relationships are remarkably independent of both soil type and climatic setting. These observations provide the basis for a series of general equations from which it is proposed Southeast Asian including Australian, and possibly worldwide background concentrations for As, Cr, Co, Cu, Ni, Pb, and Zn in soils can be derived.R. E. Hamon, M. J. McLaughlin, R. J. Gilkes, A. W. Rate, B. Zarcinas, A. Robertson, G. Cozens, N. Radford and L. Bettena

Ex post aggregate real rates of return in Canada: 1947-1976

Cover title"June 1981."Series statement handwritten on cover"This is a draft of a study to be published by the Economic Council of Canada. It is made available to participants in the Rates of Return Conference on the strict understanding that it is not to be circulated or quoted without permission from the Economic Council of Canada."Includes bibliographical references (p. 77-80

Plan de negocios de compota para beb?s a base de frutas enriquecida con quinua al mercado de Lima Metropolitana

La presente tesis desarrolla un plan de negocios de compotas para beb?s a base de frutas enriquecida con quinua para los niveles socioecon?micos B y C de Lima Metropolitana. Este plan est? orientado a demostrar la viabilidad econ?mica y financiera de fabricaci?n y comercializaci?n de compotas para beb?s. La propuesta de valor del negocio radica en ofrecer una compota de gran valor nutricional que contribuya al desarrollo de los beb?s. La quinua, al ser un alimento reconocido por su gran valor nutricional, permite a cumplir con la propuesta de valor

Coordinations between gene modules control the operation of plant amino acid metabolic networks

<p>Abstract</p> <p>Background</p> <p>Being sessile organisms, plants should adjust their metabolism to dynamic changes in their environment. Such adjustments need particular coordination in branched metabolic networks in which a given metabolite can be converted into multiple other metabolites via different enzymatic chains. In the present report, we developed a novel "Gene Coordination" bioinformatics approach and use it to elucidate adjustable transcriptional interactions of two branched amino acid metabolic networks in plants in response to environmental stresses, using publicly available microarray results.</p> <p>Results</p> <p>Using our "Gene Coordination" approach, we have identified in Arabidopsis plants two oppositely regulated groups of "highly coordinated" genes within the branched Asp-family network of Arabidopsis plants, which metabolizes the amino acids Lys, Met, Thr, Ile and Gly, as well as a single group of "highly coordinated" genes within the branched aromatic amino acid metabolic network, which metabolizes the amino acids Trp, Phe and Tyr. These genes possess highly coordinated adjustable negative and positive expression responses to various stress cues, which apparently regulate adjustable metabolic shifts between competing branches of these networks. We also provide evidence implying that these highly coordinated genes are central to impose intra- and inter-network interactions between the Asp-family and aromatic amino acid metabolic networks as well as differential system interactions with other growth promoting and stress-associated genome-wide genes.</p> <p>Conclusion</p> <p>Our novel Gene Coordination elucidates that branched amino acid metabolic networks in plants are regulated by specific groups of highly coordinated genes that possess adjustable intra-network, inter-network and genome-wide transcriptional interactions. We also hypothesize that such transcriptional interactions enable regulatory metabolic adjustments needed for adaptation to the stresses.</p

Investigating the origin of the spectral line profiles of the Hot Wolf-Rayet Star WR 2

The hot WN star WR 2 (HD 6327) has been claimed to have many singular characteristics. To explain its unusually rounded and relatively weak emission line profiles, it has been proposed that WR 2 is rotating close to break-up with a magnetically confined wind. Alternatively, the line profiles could be explained by the dilution of WR 2’s spectrum by that of a companion. In this paper, we present a study of WR 2 using near-infrared AO imaging and optical spectroscopy and polarimetry. Our spectra reveal the presence of weak photospheric absorption lines from a ∼B 2.5-4V companion, which however contributes only ∼5–10% to the total light, suggesting that the companion is a background object. Therefore, its flux cannot be causing any significant dilution of the WR star’s emission lines. The absence of intrinsic linear continuum polarization from WR 2 does not support the proposed fast rotation. Our Stokes V spectrum was not of sufficient quality to test the presence of a moderately strong organized magnetic field but our new modelling indicates that to confine the wind the putative magnetic field must be significantly stronger than was previously suggested sufficiently strong as to make its presence implausible

Utilisation of an operative difficulty grading scale for laparoscopic cholecystectomy

Background A reliable system for grading operative difficulty of laparoscopic cholecystectomy would standardise description of findings and reporting of outcomes. The aim of this study was to validate a difficulty grading system (Nassar scale), testing its applicability and consistency in two large prospective datasets. Methods Patient and disease-related variables and 30-day outcomes were identified in two prospective cholecystectomy databases: the multi-centre prospective cohort of 8820 patients from the recent CholeS Study and the single-surgeon series containing 4089 patients. Operative data and patient outcomes were correlated with Nassar operative difficultly scale, using Kendall’s tau for dichotomous variables, or Jonckheere–Terpstra tests for continuous variables. A ROC curve analysis was performed, to quantify the predictive accuracy of the scale for each outcome, with continuous outcomes dichotomised, prior to analysis. Results A higher operative difficulty grade was consistently associated with worse outcomes for the patients in both the reference and CholeS cohorts. The median length of stay increased from 0 to 4 days, and the 30-day complication rate from 7.6 to 24.4% as the difficulty grade increased from 1 to 4/5 (both p < 0.001). In the CholeS cohort, a higher difficulty grade was found to be most strongly associated with conversion to open and 30-day mortality (AUROC = 0.903, 0.822, respectively). On multivariable analysis, the Nassar operative difficultly scale was found to be a significant independent predictor of operative duration, conversion to open surgery, 30-day complications and 30-day reintervention (all p < 0.001). Conclusion We have shown that an operative difficulty scale can standardise the description of operative findings by multiple grades of surgeons to facilitate audit, training assessment and research. It provides a tool for reporting operative findings, disease severity and technical difficulty and can be utilised in future research to reliably compare outcomes according to case mix and intra-operative difficulty

Probing the rotational velocity of Galactic WO stars with spectropolarimetry

Oxygen sequence Wolf-Rayet stars (WO) are thought to be the final evolution phase of some high-mass stars, as such they may be the progenitors of Type Ic SNe as well as potential progenitors of broad-lined Ic and long gamma-ray bursts. We present the first spectropolarimetric observations of the Galactic WO stars WR93b and WR102 obtained with FORS1 on the Very Large Telescope. We find no sign of a line effect, which could be expected if these stars were rapid rotators. We also place constraints on the amplitude of a potentially undetected line effect. This allows us to derive upper limits on the possible intrinsic continuum polarization and find Pcont < 0.077 per cent and Pcont < 0.057 per cent for WR93b and WR102, respectively. Furthermore, we derive upper limits on the rotation of our WO stars by considering our results in the context of the wind compression effect. We estimate that for an edge-on case the rotational velocity of WR93b is vrot < 324 km s−1 while for WR102 vrot < 234 km s−1. These correspond to values of vrot/vcrit < 19 per cent and <10 per cent, respectively, and values of log(j) < 18.0 cm2 s−1 for WR93b and <17.6 cm2 s−1 for WR102. The upper limits found on vrot/vcrit and log(j) for our WO stars are therefore similar to the estimates calculated for Galactic Wolf-Rayet (WR) stars that do show a line effect. Therefore, although the presence of a line effect in a single WR star is indicative of fast rotation, the absence of a line effect does not rule out significant rotation, even when considering the edge-on scenario

Primary Human mDC1, mDC2, and pDC Dendritic Cells Are Differentially Infected and Activated by Respiratory Syncytial Virus

Respiratory syncytial virus (RSV) causes recurrent infections throughout life. Vaccine development may depend upon understanding the molecular basis for induction of ineffective immunity. Because dendritic cells (DCs) are critically involved in early responses to infection, their interaction with RSV may determine the immunological outcome of RSV infection. Therefore, we investigated the ability of RSV to infect and activate primary mDCs and pDCs using recombinant RSV expressing green fluorescent protein (GFP). At a multiplicity of infection of 5, initial studies demonstrated ∼6.8% of mDC1 and ∼0.9% pDCs were infected. We extended these studies to include CD1c−CD141+ mDC2, finding mDC2 infected at similar frequencies as mDC1. Both infected and uninfected cells upregulated phenotypic markers of maturation. Divalent cations were required for infection and maturation, but maturation did not require viral replication. There is evidence that attachment and entry/replication processes exert distinct effects on DC activation. Cell-specific patterns of RSV-induced maturation and cytokine production were detected in mDC1, mDC2, and pDC. We also demonstrate for the first time that RSV induces significant TIMP-2 production in all DC subsets. Defining the influence of RSV on the function of selected DC subsets may improve the likelihood of achieving protective vaccine-induced immunity