CFD Analyses and Experiments in a PAT Modeling: Pressure Variation and System Efficiency

[EN] Analysis of a PAT modeling is presented for application in water pipe systems as an interesting and promising energy converter to improve the system energy efficiency. The study is focused on the use of a Computational Fluid Dynamics (CFD) model in conjunction with laboratory data for representing PAT performance. The first stage of the procedure concerns a systematic analysis of the role played by the characteristic PAT parameters in the computational mesh definitions of the CFD model, with the aim of defining the most efficient set of capturing the main features of the PAT behaviour under different operating conditions. In the second stage, comparisons of CFD results and experiments were carried out to examine some system components for better understanding the PAT response. Specifically, the behavior of the pressure distribution along the PAT installation when implemented in a water pipe system are analyzed, and the links between pressure variation and the head drop in different system components responsible for the head losses and net head definition are also examined.This research is supported by the "Program to support the academic career of the faculty of the Universitat Politecnica de Valencia 2016/2017 in the project 'Maximization of the global efficiency in PATs in laboratory facility of the first author. The authors wish to thank to the project REDAWN (Reducing Energy Dependency in Atlantic Area Water Networks) EAPA_198/2016 from INTERREG ATLANTIC AREA PROGRAMME 2014-2020 and CERIS (CEHIDRO-IST), the Hydraulic Laboratory, for the support in the conceptual developments and the experiments on PATs.Pérez-Sánchez, M.; Simao, M.; López Jiménez, PA.; Ramos, HM. (2017). CFD Analyses and Experiments in a PAT Modeling: Pressure Variation and System Efficiency. Fluids. 2(4):1-17. doi:10.3390/fluids2040051S1172

Mathematic Modelling of a Reversible Hydropower System: Dynamic Effects in Turbine Mode

Over the past few years, there has been significant interest in the importance of reversible hydro-pumping systems due to their favorable flexibility and economic and environmental characteristics. When designing reversible lines, it is crucial to consider dynamic effects and corresponding extreme pressures that may occur during normal and emergency operating scenarios. This research describes essentially the turbine operation, although various boundary elements are mathematically formulated and presented to provide an understanding of the system complexity. Different numerical approaches are presented, based on the 1D method of characteristics (MOC) for the long hydraulic circuit, the dynamic turbine runner simulation technique for the behavior of the power station in turbine mode and the interaction with the fluid in the penstock, and a CFD model (2D and 3D) to analyze the flow behavior crossing the runner through the velocity fields and pressure contours. Additionally, the simulation results have been validated by experimental tests on different setups characterized by long conveyance systems, consisting of a small scale of pumps as turbines (at IST laboratory) and classical reaction turbines (at LNEC laboratory). Mathematical models, together with an intensive campaign of experiments, allow for the estimation of dynamic effects related to the extreme transient pressures, the fluid-structure interaction with rotational speed variation, and the change in the flow. In some cases, the runaway conditions can cause an overspeed of 2–2.5 of the rated rotational speed (NR) and an overpressure of 40–65% of the rated head (HR), showing significant impacts on the pressure wave propagation along the entire hydraulic circuit. Sensitivity analyses based on systematic numerical simulations of PATs (radial and axial types) and reaction turbines (Francis and Kaplan types) and comparisons with experiments are discussed. These evaluations demonstrate that the full-load rejection scenario can be dangerous for turbomachinery with low specific-speed (ns) values, in particular when associated with long penstocks and fast guide vane (or control valve) closing maneuver. © 2023 by the authors

Aorta Ascending Aneurysm Analysis Using CFD Models towards Possible Anomalies

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Challenges in the COVID-19 vaccination era: Prioritization of vaccines among essential workers in Mexico

The coronavirus disease-2019 (COVID-19) pandemic gave rise to a massive global health concern that has placed an unprecedented strain on healthcare systems, education and economy. The recent vaccine roll-out gave humanity a glimpse of hope. However, more than 50% of the vaccine supply has been acquired by high-income countries, forcing low- and middle-income countries to prioritize who should be vaccinated. In Mexico, the first phase of the vaccination program prioritized healthcare personnel working in front-line COVID-19 public institutions. The second phase was planned for the remaining healthcare workers attending at both COVID and non-COVID areas. The government, however, aiming to reopen schools, decided to vaccinate teachers instead. This raised several concerns, since Mexico tops the ranking of deaths among healthcare workers due to COVID-19 worldwide. Furthermore, the possible framing of vaccines as a political tool has caused commotion among the Mexican people and media, especially since 2021 is the Midterm Election year in Mexico, and the Teachers’ Union has historically played an essential role in this matter. Therefore, it is relevant to share the vaccination experience in resource-constrained settings to provide help and advice to reach an optimal strategy and deflate this pandemic

Expansion planning of power distribution systems considering reliability : a comprehensive review

One of the big concerns when planning the expansion of power distribution systems (PDS) is reliability. This is defined as the ability to continuously meet the load demand of consumers in terms of quantity and quality. In a scenario in which consumers increasingly demand high supply quality, including few interruptions and continuity, it becomes essential to consider reliability indices in models used to plan PDS. The inclusion of reliability in optimization models is a challenge, given the need to estimate failure rates for the network and devices. Such failure rates depend on the specific characteristics of a feeder. In this context, this paper discusses the main reliability indices, followed by a comprehensive survey of the methods and models used to solve the optimal expansion planning of PDS considering reliability criteria. Emphasis is also placed on comparing the main features and contributions of each article, aiming to provide a handy resource for researchers. The comparison includes the decision variables and reliability indices considered in each reviewed article, which can be used as a guide to applying the most suitable method according to the requisites of the system. In addition, each paper is classified according to the optimization method, objective type (single or multiobjective), and the number of stages. Finally, we discuss future research trends concerning the inclusion of reliability in PDS expansion planning

Colonic transit in children and adolescents with chronic constipation

AbstractObjectiveThe aim of this study was to assess clinical features and colonic transit patterns in Brazilian children with refractory constipation.MethodsFrom 2010 to 2013, 79 constipated patients received follow-up care in a tertiary hospital. Of these patients, 28 (aged 8–14 years) were refractory to conventional therapy and underwent a simplified visual method of nuclear colonic transit study, by ingestion of a liquid meal containing 9.25MBq/kg of 99mTc-phytate. Abdominal static images were taken immediately and at two, six, 24, 30, and 48h after ingestion for qualitative analysis of the radio marker progression through the colon.ResultsTwo patterns of colonic transit were found: slow colonic transit (SCT, n=14), when images at 48h showed a larger part of the tracer remained in proximal and transverse colon, and distal retention (DR, n=14), when after 30h, the radio isotope passed the transverse colon and was retained in the rectosigmoid up to 48h. The SCT and DR group included, respectively, nine and ten males; median ages in the nuclear study of 11 and 10 years, p=0.207; median duration of constipation of seven and six years, p=0.599. Constipation appearing during first year age (p=0.04) and report of soft stools (p=0.02) were more common in SCT patients. Palpable abdominal fecal impaction was found only in DR group. Appendicostomy for antegrade continence enema was successful in 4/12 (30%) of SCT patients (median follow-up: 2.4 years).ConclusionNuclear transit study distinguished two colonic dysmotility patterns and was useful for guiding refractory patients to specific therapies

Quando a expressão plástica e a matemática dão as mãos

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Antifungal Potential of Copper(II), Manganese(II) and Silver(I) 1,10-Phenanthroline Chelates Against Multidrug-Resistant Fungal Species Forming the Candida haemulonii Complex: Impact on the Planktonic and Biofilm Lifestyles

Candida haemulonii, Candida haemulonii var. vulnera and Candida duobushaemulonii, which form the C. haemulonii complex, are emerging etiologic agents of fungal infections known to be resistant to the most commonly used antifungals. The well-established anti-Candida potential ofmetal complexes containing 1,10-phenanthroline (phen) ligands encouraged us to evaluate different copper(II), manganese(II), and silver(I) phen chelates for their ability to inhibit planktonic growth and biofilm of C. haemulonii species complex. Two novel coordination complexes, {[Cu(3,6,9-tdda)(phen)2].3H2O.EtOH}n and [Ag2(3,6,9-tdda)(phen)4].EtOH (3,6,9-tddaH2 = 3,6,9-trioxaundecanedioic acid), were synthesized in a similar fashion to the other, previously documented, sixteen copper(II), manganese(II), and silver(I) chelates employed herein. Three isolates of each C. haemulonii species complex were used and the effect of the metal chelates on viability was determined utilizing the CLSI standard protocol and on biofilm-growing cells using the XTT assay. Cytotoxicity of the chelates was evaluated by the MTT assay, employing lung epithelial cells. The majority of the metal chelates were capable of interfering with the viability of planktonic-growing cells of all the fungal isolates

The Health-Promoting Potential of Salix spp. Bark Polar Extracts: Key Insights on Phenolic Composition and In Vitro Bioactivity and Biocompatibility

Salix spp. have been exploited for energy generation, along with folk medicine use of bark extracts for antipyretic and analgesic benefits. Bark phenolic components, rather than salicin, have demonstrated interesting bioactivities, which may ensure the sustainable bioprospection of Salix bark. Therefore, this study highlights the detailed phenolic characterization, as well as the in vitro antioxidant, anti-hypertensive, Staphylococcus aureus growth inhibitory effects, and biocompatibility of Salix atrocinerea Brot., Salix fragilis L., and Salix viminalis L. bark polar extracts. Fifteen phenolic compounds were characterized by ultra-high-performance liquid chromatography-ultraviolet detection-mass spectrometry analysis, from which two flavan-3-ols, an acetophenone, five flavanones, and a flavonol were detected, for the first time, as their bark components. Salix bark extracts demonstrated strong free radical scavenging activity (5.58–23.62 µg mL−1 IC50 range), effective inhibition on angiotensin-I converting enzyme (58–84%), and S. aureus bactericidal action at 1250–2500 µg mL−1 (6–8 log CFU mL−1 reduction range). All tested Salix bark extracts did not show cytotoxic potential against Caco-2 cells, as well as S. atrocinerea Brot. and S. fragilis L. extracts at 625 and 1250 µg mL−1 against HaCaT and L929 cells. These valuable findings can pave innovative and safer food, nutraceutical, and/or cosmetic applications of Salix bark phenolic-containing fractions.info:eu-repo/semantics/publishedVersio