558 research outputs found
A study of real-time computer graphic display technology for aeronautical applications
Hardware, algorithms and software for real-time raster graphics were designed and implemented
A study of real-time computer graphic display technology for aeronautical applications
The development, simulation, and testing of an algorithm for anti-aliasing vector drawings is discussed. The pseudo anti-aliasing line drawing algorithm is an extension to Bresenham's algorithm for computer control of a digital plotter. The algorithm produces a series of overlapping line segments where the display intensity shifts from one segment to the other in this overlap (transition region). In this algorithm the length of the overlap and the intensity shift are essentially constants because the transition region is an aid to the eye in integrating the segments into a single smooth line
Packing dimension of mean porous measures
We prove that the packing dimension of any mean porous Radon measure on
may be estimated from above by a function which depends on mean
porosity. The upper bound tends to as mean porosity tends to its maximum
value. This result was stated in \cite{BS}, and in a weaker form in \cite{JJ1},
but the proofs are not correct. Quite surprisingly, it turns out that mean
porous measures are not necessarily approximable by mean porous sets. We verify
this by constructing an example of a mean porous measure on
such that for all mean porous sets .Comment: Revised versio
Calculus and heat flow in metric measure spaces and applications to spaces with Ricci bounds from below
This paper is devoted to a deeper understanding of the heat flow and to the
refinement of calculus tools on metric measure spaces (X,d,m). Our main results
are:
- A general study of the relations between the Hopf-Lax semigroup and
Hamilton-Jacobi equation in metric spaces (X,d).
- The equivalence of the heat flow in L^2(X,m) generated by a suitable
Dirichlet energy and the Wasserstein gradient flow of the relative entropy
functional in the space of probability measures P(X).
- The proof of density in energy of Lipschitz functions in the Sobolev space
W^{1,2}(X,d,m).
- A fine and very general analysis of the differentiability properties of a
large class of Kantorovich potentials, in connection with the optimal transport
problem.
Our results apply in particular to spaces satisfying Ricci curvature bounds
in the sense of Lott & Villani [30] and Sturm [39,40], and require neither the
doubling property nor the validity of the local Poincar\'e inequality.Comment: Minor typos corrected and many small improvements added. Lemma 2.4,
Lemma 2.10, Prop. 5.7, Rem. 5.8, Thm. 6.3 added. Rem. 4.7, Prop. 4.8, Prop.
4.15 and Thm 4.16 augmented/reenforced. Proof of Thm. 4.16 and Lemma 9.6
simplified. Thm. 8.6 corrected. A simpler axiomatization of weak gradients,
still equivalent to all other ones, has been propose
Optimal maps and exponentiation on finite dimensional spaces with Ricci curvature bounded from below
We prove existence and uniqueness of optimal maps on spaces under the assumption that the starting measure is absolutely continuous. We also discuss how this result naturally leads to the notion of exponentiation. \ua9 2015, Mathematica Josephina, Inc
Motive-demand dynamics creating a social context for students’ learning experiences in a making and design environment
Making and design environments, often referred to as makerspaces, have aroused recent educational interest. These environments typically consist of spaces that support interest-driven engagement in hands-on creative activities with a range of digital artefacts. Although a variety of benefits from participating in making and design activities have been proposed, we currently have limited understanding of students’ learning experiences in makerspaces situated in schools. Following Hedegaards’ conceptualisations, we investigate motive-demand dynamics in students’ social activity in a school-based digital making and design environment, ‘The FUSE Studio’. We highlight our findings via vignettes selected from 65 h of video recordings of 94 students (aged between 9 and 12 years old) carrying out activities; the recordings were collected intermittently from an elective course over one semester. Our study illustrates how the students’ learning experiences were shaped through tension-laden interplay between the motives and demands of their activity situated across personal, relational and institutional contexts. The findings make visible how established ways of working and being at school interacted and came into tension with the students’ motive orientations, thereby limiting and at times transforming the social context of their learning. Our work also demonstrates how the analysis of motive-demand dynamics offers one useful conceptual tool to unpack students’ learning experiences in novel learning environments.Peer reviewe
Role of mastitis in on-farm deaths of Finnish dairy cows
According to our recent necropsy-based study, mastitis is the most common underlying diagnosis of on-farm deaths in Finnish dairy cows. However, it remained unanswered to what extent mastitis has contributed to death of all necropsied cows. In the present study, based on histopathology, we detected one-third of the necropsied dairy cows having active inflammatory udder lesions (n = 110). The role of mastitis varied and was interpreted by causes of death (underlying, intermediate, immediate, other significant). Mastitis was most commonly the underlying (28%) or both immediate and underlying cause of death (48%), and only seldom was it the immediate (4%) or intermediate (4%) cause of death. Mastitis occurred either as the only cause leading to death (mastitis only, MO; 39%), or with many other contributing diseases (multiple diseases, MD; 61%), which were interacting with mastitis and together leading to death. Between these groups (MO vs. MD), time of mastitis occurrence during lactation, producer-reported duration of illness, clinical signs, and medication differed, as well the histopathologic severity of mastitis. The cases where mastitis was the only initial insult occurred evenly throughout the entire lactation, but the cases with many interacting diseases were clustered in early lactation. In MD cows, cases of mastitis occurred concurrently with metritis (31%), aspiration pneumonia (24%), acute trauma or dystocia (15%), or with other diseases, such as ketosis, hepatic lipidosis, rumenitis, and abomasal diseases. For a pathologist, the gross mastitis diagnosis was most challenging at the beginning of the lactation, especially if inflammation was mild to moderate, suggesting the value of histopathologic examination being highest at that time. Also, producers reported mastitis signs less frequently if cow had many simultaneously occurring diseases. Therefore, even if clinical signs of other diseases are present, the udder should be considered a potential cause of illness and should be examined, especially in dry and transition-period cows
The Dutch Healthy Diet Index : development, evaluation, and application
The Dutch Healthy Diet index – Development, Evaluation, and Application Linde van Lee Abstract Background: Dietary indices evaluate the conformity of an individual’s diet with pre-defined standards. Generally, dietary guidelines are used for this purpose. As no index based on the current dietary guidelines was available in the Netherlands, the aim of the present thesis was to develop, evaluate, and apply a dietary index for use in the country. Methods and results: The Dutch Healthy Diet index (DHD-index) was developed on the basis of the 2006 Dutch dietary guidelines using data relating to 749 young adults who completed two 24-hour recalls in the Dutch national food consumption survey 2003. The index comprises ten components on physical activity, vegetables, fruit, dietary fibre, saturated fatty acids, trans fatty acids, consumption occasions with acidic drinks and foods, sodium, and alcohol. Scores for each component range between 0 (no adherence) and 10 (complete adherence) points. The DHD-index was inversely associated with energy intake and positively associated with most micronutrient intakes when adjusted for energy intake. We compared the DHD-index score based on two 24-hour recalls with the index based on the food frequency questionnaires (FFQ) of 121 adults from the European Food Consumption Validation study. We revealed an acceptable correlation (r=0.48) and absolute agreement between the indices based on the two methods. The prospective relationship with mortality outcomes was studied in 3593 of the Rotterdam Study participants who were followed for 20 years. The DHD-index per 10 points increment was associated with a 9% (95% CI 0.87-0.96) risk reduction for all-cause mortality, and non-significantly associated with risk reductions for cardiovascular disease, coronary heart disease, and stroke mortality. Among women, shared dinners were associated with lower DHD-index scores for that day than solo dinners in 1740 participants who contributed multiple 24-hour recalls in the Nutrition Questionnaires plus study. Among men and women, dinners shared with family members were associated with a higher DHD-index score on that day than dinners shared with others. Furthermore, in a subsample of 1235 participants in the Nutrition Questionnaires plus study, we evaluated the DHD-index based on the newly developed 34-item DHD-FFQ, a short questionnaire to assess diet quality in time-limited settings. The DHD-index based on the DHD-FFQ showed an acceptable correlation (r=0.56) with the index based on a 180-item FFQ, but showed a large variation in bias at individual level. Conclusions: The DHD-index based on an FFQ, on multiple 24-hour recalls, or on the DHD-FFQ was considered a valid tool to rank participants according to their diet quality. The DHD-index was therefore considered useful to monitor populations, study diet–disease associations, and identify subpopulations at risk of poor diet quality.</p
Ruthenium-Mediated 18F-Fluorination and Preclinical Evaluation of a New CB1 Receptor Imaging Agent [18F]FPATPP
Cannabinoid receptor 1 (CB1R) controls various physiological and pathological conditions, including memory, motivation, and inflammation, and is thus an interesting target for positron emission tomography (PET). Herein, we report a ruthenium-mediated radiolabeling synthesis and preclinical evaluation of a new CB1R specific radiotracer, [18F]FPATPP. [18F]FPATPP was produced with 16.7 ± 5.7% decay-corrected radiochemical yield and >95 GBq/μmol molar activity. The tracer showed high stability, low defluorination, and high specific binding to CB1Rs in mouse brain.</p
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