412 research outputs found
Dislocation core field. I. Modeling in anisotropic linear elasticity theory
Aside from the Volterra field, dislocations create a core field, which can be
modeled in linear anisotropic elasticity theory with force and dislocation
dipoles. We derive an expression of the elastic energy of a dislocation taking
full account of its core field and show that no cross term exists between the
Volterra and the core fields. We also obtain the contribution of the core field
to the dislocation interaction energy with an external stress, thus showing
that dislocation can interact with a pressure. The additional force that
derives from this core field contribution is proportional to the gradient of
the applied stress. Such a supplementary force on dislocations may be important
in high stress gradient regions, such as close to a crack tip or in a
dislocation pile-up
F-02: Antibiothérapies anti-SARM dans le traitement probabiliste des bactériémies à Staphylococcus aureus au CHU d'Angers
Introduction â objectifs
La résistance à la méticilline du Staphylococcus aureus (SA) ne cesse de diminuer en France. Nous avons évalué la prescription des antibiothérapies probabilistes dans les bactériémies à SA et leur impact clinique.
Matériels et méthodes
Il sâagit dâune Ă©tude rĂ©trospective incluant les bactĂ©riĂ©mies Ă Staphylococcus aureus sur le CHU dâAngers entre novembre 2012 et septembre 2013 avec recueil de lâantibiothĂ©rapie prescrite au rendu « cocci gram (CG)+ », Ă J5, hospitalisation depuis plus de 5 jours ou dans les six derniers mois, signes de gravitĂ© clinique, mortalitĂ© Ă J5.
RĂ©sultats
Nous avons inclus 146 Ă©pisodes de bactĂ©riĂ©mies. A lâannonce de CG+, 10 patients Ă©taient dĂ©cĂ©dĂ©s, 38,2 % ont reçu un anti-SARM (n = 52), 54,4 % un anti-SASM (n = 74), 7,4 % aucun antibiotique (n = 10). Parmi les bactĂ©riĂ©mies Ă SARM (n = 23), 60,9 % (n = 14) ont reçu une antibiothĂ©rapie initiale Ă visĂ©e SARM contre 36,3 % (n = 41) pour les bactĂ©riĂ©mies Ă SASM (n = 113) (OR = 2,71, p = 0,03). Cette adaptation semble influencĂ©e par une hospitalisation rĂ©cente (OR = 1,82 ; p = 0,33) et la prĂ©sence de signes de gravitĂ© (OR = 1,87, p = 0,23). Dans 21,4 % (n = 6) des bactĂ©riĂ©mies Ă SASM, lâantibiothĂ©rapie anti-SARM nâa pas Ă©tĂ© dĂ©secaladĂ©e. La mortalitĂ© Ă J5 est 13 %. Lâabsence dâantibiothĂ©rapie dans les 24 premiĂšres heures (OR = 2,97 ; p = 0,046) et une prescription de C3G (OR = 5,2, p = 0,05) en monothĂ©rapie augmentent le risque de dĂ©cĂšs Ă J5.
Conclusion
LâantibiothĂ©rapie initale semble adaptĂ©e Ă lâhistoire et la prĂ©sentation des patients. Lâinitiation sans dĂ©lai, la visĂ©e staphylococcique et la dĂ©sescalade sont les Ă©lĂ©ments importants du traitement
An update on THORPEX-related research in data assimilation and observing strategies
International audienceThe international programme "THORPEX: a World Weather Research Programme" provides a framework in which to tackle the challenge of improving the forecast skill of high-impact weather through international collaboration between academic institutions, operational forecast centres, and users of forecast products. The objectives of the THORPEX Data Assimilation and Observation Strategy Working Group (DAOS-WG) are two-fold. The primary goal is to assess the impact of observations and various targeting methods to provide guidance for observation campaigns and for the configuration of the Global Observing System. The secondary goal is to setup an optimal framework for data assimilation, including aspects such as targeted observations, satellite data, background error covariances and quality control. The Atlantic THORPEX Regional campaign, ATReC, in 2003, has been very successful technically and has provided valuable datasets to test targeting issues. Various data impact experiments have been performed, showing a small but very slightly positive impact of targeted observations. Projects of the DAOS-WG include working on the AMMA field experiment, in the context of IPY and to prepare the future THORPEX-PARC field campaign in the Pacific by comparing sensitivity of the forecasts to observations between several groups
On some aspects of the geometry of differential equations in physics
In this review paper, we consider three kinds of systems of differential
equations, which are relevant in physics, control theory and other applications
in engineering and applied mathematics; namely: Hamilton equations, singular
differential equations, and partial differential equations in field theories.
The geometric structures underlying these systems are presented and commented.
The main results concerning these structures are stated and discussed, as well
as their influence on the study of the differential equations with which they
are related. Furthermore, research to be developed in these areas is also
commented.Comment: 21 page
Comparison between classical potentials and ab initio for silicon under large shear
The homogeneous shear of the {111} planes along the direction of bulk
silicon has been investigated using ab initio techniques, to better understand
the strain properties of both shuffle and glide set planes. Similar
calculations have been done with three empirical potentials, Stillinger-Weber,
Tersoff and EDIP, in order to find the one giving the best results under large
shear strains. The generalized stacking fault energies have also been
calculated with these potentials to complement this study. It turns out that
the Stillinger-Weber potential better reproduces the ab initio results, for the
smoothness and the amplitude of the energy variation as well as the
localization of shear in the shuffle set
Comparison of cloud products within IASI footprints for the assimilation of cloudy radiances
This article compares different methods of deriving cloud properties in the footprint of the Infrared Atmospheric Sounding Interferometer (IASI), onboard the European MetOp satellite. Cloud properties produced by ten operational schemes are assessed and an intercomparison of the products for a 12 h global acquisition is presented. Clouds cover a large part of the Earth, contaminating most of the radiance data. The estimation of cloud top height and effective amount within the sounder footprint is an important step towards the direct assimilation of cloud-affected radiances. This study first examines the capability of all the schemes to detect and characterize the clouds for all complex situations and provides some indications of confidence in the data. Then the dataset is restricted to thick overcast single layers and the comparison shows a significant agreement between all the schemes. The impact of the retrieved cloud properties on the residuals between calculated cloudy radiances and observations is estimated in the long-wave part of the spectrum
Bioluminescence intensity modeling and sampling strategy optimization
Author Posting. © American Meteorological Society 2005. This article is posted here by permission of American Meteorological Society for personal use, not for redistribution. The definitive version was published in Journal of Atmospheric and Oceanic Technology 22 (2005): 1267â1281, doi:10.1175/JTECH1760.1.The focus of this paper is on the development of methodology for short-term (1â3 days) oceanic bioluminescence (BL) predictions and the optimization of spatial and temporal bioluminescence sampling strategies. The approach is based on predictions of bioluminescence with an advectionâdiffusionâreaction (tracer) model with velocities and diffusivities from a circulation model. In previous research, it was shown that short-term changes in some of the salient features in coastal bioluminescence can be explained and predicted by using this approach. At the same time, it was demonstrated that optimization of bioluminescence sampling prior to the forecast is critical for successful short-term BL predictions with the tracer model. In the present paper, the adjoint to the tracer model is used to study the sensitivity of the modeled bioluminescence distributions to the sampling strategies for BL. The locations and times of bioluminescence sampling prior to the forecast are determined by using the adjoint-based sensitivity maps. The approach is tested with bioluminescence observations collected during August 2000 and 2003 in the Monterey Bay, California, area. During August 2000, BL surveys were collected during a strong wind relaxation event, while in August 2003, BL surveys were conducted during an extended (longer than a week) upwelling-favorable event. The numerical bioluminescence predictability experiments demonstrated a close agreement between observed and model-predicted short-term spatial and temporal changes of the coastal bioluminescence.This work has been supported by
the Ocean Optics and Biology and Physical Oceanography
Programs of the Office of Naval Research. Shulmanâs
support is through the NRL âUse of a Circulation
Model to Enhance Predictability of Bioluminescence
in the Coastal Oceanâ project sponsored by the
Office of Naval Research
A case report of Mycoplasma hominis brain abscess identified by MALDI-TOF mass spectrometry
We report the case of a 43-year-old man with a Mycoplasma hominis brain abscess occurring after a cranial trauma, which was identified by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). The presence of colonies on classic blood agar plates and the use of MALDI-TOF MS, a valuable diagnostic tool that identified M. hominis due to its presence in the VITEK MS database, allowed the rapid diagnosis of this infection
- âŠ