Fitting a Model to Students' Cognitive engagement: A Step Towards Accountable Education in Medical Education

Introduction: Motivation is one of the most important effective factors in learning. It can lead to long-lasting learning in connection with identity. Creating an appropriate setting for development and actualization of students with different Scientific, social and cultural abilities is one of the accountable education package’s The Health System Evaluation Plan. Whereas emotion regulation and management is one of the important needs of students and empowering them in this field is a necessity. Method: Present study is a kind of non-experimental design. To speak more precisely, it is a type of correlations design which has analyzed a structural pattern of variables relationship, done in 2016 in Sabzevar university of medical Sciences, 720 students was selected using multistage cluster sampling as  the sample group  and employed Berzonsky’s identity style Inventory (ISI-3), achievement goals scale of Midgley et al(PALS), and motivated strategies for learning questionnaire (MSLQ). Data was analyzed using path analysis. Results: nformational identity style has both direct and indirect effect (through the intervening role of mastery goals) on cognitive engagement (P<0.01). Normative identity style has an effect The path from diffuse-avoidant identity style to performance-avoidance goals was excluded from fitted model, fitted model predicts 41% of cognitive engagement. Conclusion: Inorder to improve learning, cognitive engagement (mental efforts) can be targeted using motivational and identity variables

Fitting a Model to Students' Cognitive engagement: A Step Towards Accountable Education in Medical Education

Introduction: Motivation is one of the most important effective factors in learning. It can lead to long-lasting learning in connection with identity. Creating an appropriate setting for development and actualization of students with different Scientific, social and cultural abilities is one of the accountable education package’s The Health System Evaluation Plan. Whereas emotion regulation and management is one of the important needs of students and empowering them in this field is a necessity. Method: Present study is a kind of non-experimental design. To speak more precisely, it is a type of correlations design which has analyzed a structural pattern of variables relationship, done in 2016 in Sabzevar university of medical Sciences, 720 students was selected using multistage cluster sampling as  the sample group  and employed Berzonsky’s identity style Inventory (ISI-3), achievement goals scale of Midgley et al(PALS), and motivated strategies for learning questionnaire (MSLQ). Data was analyzed using path analysis. Results: nformational identity style has both direct and indirect effect (through the intervening role of mastery goals) on cognitive engagement (P<0.01). Normative identity style has an effect The path from diffuse-avoidant identity style to performance-avoidance goals was excluded from fitted model, fitted model predicts 41% of cognitive engagement. Conclusion: Inorder to improve learning, cognitive engagement (mental efforts) can be targeted using motivational and identity variables

Grounded theory of idea of the quality of teaching creative vision student Nursing and Human Sciences

Introduction: Today, university professors must substitute traditional strategies of conveying information for new and creative educational strategies. This study was conducted to determine the views of nursing students on the quality of creative teaching. Method: The present qualitative study was conducted in the School of Nursing and Midwifery of Mashhad University of Medical Sciences, Iran, in the year 2013. Data were collected through semi-structured interviews. The study participants (20 students) were selected using purposive sampling. To analyze the data, the coding method attributed to Strauss and Corbin was used. The validity of findings was ensured through member assessment, deep description, and prolonged exposure to the research environment. Results: In the present study, three main themes in students’ views of creative teaching were achieved that included professional characteristics of the lecturer in teaching, students’ characteristics, and learning conditions. Conclusion: Professional development of teachers, students’ characteristics, and learning conditions are factors that determine the quality of creative teaching. Hence, improving conditions for the professional development of lecturers, and consideration of students’ characteristics and learning conditions can aid the creation of an environment for creative teaching. Keywords: : Quality - Creative Teaching - Students - The theory underlyin

Antioxidant and cytotoxic properties of protein hydrolysates obtained from enzymatic hydrolysis of Klunzinger’s mullet (Liza klunzingeri) muscle

Today, consumers are looking for functional foods that promote health and prevent certain diseases in addition to provide nutritional requirements. This study aimed to evaluate the antioxidant and cytotoxic properties of Liza klunzingeri protein hydrolysates. Fish protein hydrolysates (FPHs) were prepared from L. klunzingeri muscle using enzymatic hydrolysis with papain at enzyme/substrate ratios of 1:25 and 1:50 for 45, 90 and 180 min. The antioxidant activities of the FPHs were investigated through five antioxidant assays. The cytotoxic effects on 4T1 carcinoma cell line were also evaluated. The amino acid composition and molecular weight distribution of the hydrolysate with the highest antioxidant activity were determined by HPLC. All six FPHs exhibited good scavenging activity on ABTS (IC50=0.60-0.12 mg/mL), DPPH (IC50= 3.18-2.08 mg/mL), and hydroxyl (IC50=4.13-2.07 mg/mL) radicals. They also showed moderate Fe+2 chelating capacity (IC50=2.12-12.60 mg/mL) and relatively poor ferric reducing activity (absorbance at 70 nm= 0.01-0.15, 5 mg/mL). In addition, all hydrolysates showed cytotoxic activities against the 4T1 cells (IC50=1.62-2.61 mg/mL). 94.6% of peptide in hydrolysate with the highest antioxidant activity had molecular weight less than 1,000 Da. L. klunzingeri protein hydrolysates show significant antioxidant and anticancer activities in vitro and are suggested to be used in animal studies

New diagnostic criteria for inguinal hernia based on ultrasound examination

Background: According to increasing use of ultrasound in the diagnosis of inguinal herniation, this study was designed to evaluate the cross-sectional area of the inguinal canal in patients with inguinal herniation and its increase with Valsalva maneuver. We also compared the obtained values with those of normal population. Methods: a cross-sectional study, 52 normal persons and 35 cases with inguinal hernia were assessed. The cross-sectional area of the inguinal canal was measured in all subjects and data was analyzed using Student's t-test and Pearson's correlation tests in SPSS. Receiver operator characteristic (ROC) curves were traced to define cut-off points. Findings: Valsalva maneuver caused significantly greater increase in the cross-sectional area of the inguinal canal among patients than in the normal group. The cut-off point of the cross-sectional area of inguinal canal was 63.5 mm2 in neutral state and 72.5 mm2 with Valsalva maneuver (increase rate: 34 mm2). In the absence of Valsalva maneuver, a cross-sectional area of the inguinal canal of greater than 63.5 mm2 is predictive of inguinal hernia (with 91 sensitivity and 98 specificity). Otherwise, values greater than 72.5 mm2 will be predictive of inguinal hernia (with 100 sensitivity and 98 specificity). Inguinal hernia will also be suspected if Valsalva maneuver increases the cross-sectional area of the inguinal canal by more than 34 mm2 (with 91 sensitivity and 100 specificity). Conclusion: The following diagnostic criteria are suggested for diagnosis of inguinal hernia through ultrasound examination: the presence of bowel loop within the inguinal canal, a cross-sectional area of the inguinal canal > 63.5 mm2 without Valsalva maneuver and > 72.5 mm2 with Valsalva maneuver, an increase of > 34 mm2 in the cross-sectional area of the inguinal canal with Valsalva maneuver, and a > 0.5 cm movement of the spermatic cord with Valsalva maneuver

The Relationship of Serum Levels of Gamma Interferon and its Receptor (CD119) to Development of BCG Axillary Lymphadenopathy

Background: Lymphadenitis is the most common complication of BCG vaccination in children. Interferon-gamma (IFN-gamma) plays a key role in immune response to Mycobacterial infections. In this study, the relationship of serum levels of IFN-gamma and its receptor (CD119) to development of Bacillus Calmette Guerin (BCG) axillary lymphadenopathy was investigated. Materials and Methods: In this case-control study, 45 children with axillary lymphadenopathy and 45 healthy children matched by age and sex were included. Two ml peripheral blood was collected in tubes containing anticoagulants. Then, level of IFN-gamma was measured by ELISA and the level of CD119 expression in the peripheral blood mononuclear cell (PBMC) was measured by flow cytometry. Data were analyzed using SPSS software version 22.0. Results: Totally, 90 children were enrolled in this study, which consisted of 30 girls and 60 boys. The mean age of participants was 14.5 +/- 6.5 months in case group and 15.2 +/- 7.1 months in control group. respectively (p=0.61). The level of IFN-gamma was significantly lower in case group than in control group (p0.05). There was no significant relationship of age and sex to BCG (INF and PBMC) lymphadenopathy (p>0.05). Conclusion: Based on the results. IFN-gamma level was significantly lower in the BCG lymphadenopathy group than in the control group. Levels of IFN-gamma R (CD119 cellular level in PBMC) in two groups did not show a significant relationship. Keywords:Bacillus Calmette Guerin; CD119; Children; Interferon gamma; Lymphadenopath

Antioxidant and cytotoxic properties of protein hydrolysates obtained from enzymatic hydrolysis of Klunzinger’s mullet (Liza klunzingeri) muscle

Today, consumers are looking for functional foods that promote health and prevent certain diseases in addition to provide nutritional requirements. This study aimed to evaluate the antioxidant and cytotoxic properties of Liza klunzingeri protein hydrolysates. Fish protein hydrolysates (FPHs) were prepared from L. klunzingeri muscle using enzymatic hydrolysis with papain at enzyme/substrate ratios of 1:25 and 1:50 for 45, 90 and 180 min. The antioxidant activities of the FPHs were investigated through five antioxidant assays. The cytotoxic effects on 4T1 carcinoma cell line were also evaluated. The amino acid composition and molecular weight distribution of the hydrolysate with the highest antioxidant activity were determined by HPLC. All six FPHs exhibited good scavenging activity on ABTS (IC50=0.60-0.12 mg/mL), DPPH (IC50= 3.18-2.08 mg/mL), and hydroxyl (IC50=4.13-2.07 mg/mL) radicals. They also showed moderate Fe+2 chelating capacity (IC50=2.12-12.60 mg/mL) and relatively poor ferric reducing activity (absorbance at 70 nm= 0.01-0.15, 5 mg/mL). In addition, all hydrolysates showed cytotoxic activities against the 4T1 cells (IC50=1.62-2.61 mg/mL). 94.6% of peptide in hydrolysate with the highest antioxidant activity had molecular weight less than 1,000 Da. L. klunzingeri protein hydrolysates show significant antioxidant and anticancer activities in vitro and are suggested to be used in animal studies. Keywords: Antioxidant activity; Cytotoxic effect; Protein hydrolysate; Liza klunzinger

Correlation between the Intensity of Helicobacter pylori

Background. The most common cause of chronic gastritis is infection with Helicobacter pylori. Identifying the relationship between intensities of colonization and activity of gastritis helps the clinician in more effective treatment and posttreatment follow-ups. Methods. In this cross-sectional study, endoscopic gastric biopsy samples of 544 patients who complained symptoms of dyspepsia for more than three months referring to the laboratory were studied. To determine the colonization rate of H. pylori and other pathological findings, Giemsa and H&E stains were, respectively, used. Results. Among 544 subjects, 47 (8.64%) patients had no gastritis, 203 (37.32%) had mild gastritis, 278 (10.51%) suffered moderate gastritis, and 16 (2.94%) had severe gastritis. In this study, patients with mild H. pylori colonization rates had the highest level of mild activity (33.52%); in contrast, those with severe H. pylori colonization had the highest level of severe activity (43.75%). 93.96% of people with severe H. pylori colonization suffered from moderate and severe chronic gastritis. There is a significant statistical relationship between the intensity of H. pylori colonization and histopathological findings including intestinal metaplasia, atrophy, and lymphoid follicle formation. Conclusions. According to the present study, with increasing intensity of H. pylori colonization, chronicity and activity of gastritis and its complications increase

The protective effect of Liza klunzingeri protein hydrolysate on carbon tetrachloride-induced oxidative stress and toxicity in male rats

Objective(s): Today, consumers are looking for food products providing health benefits in addition to meeting the basic nutritional needs of the body. This study aimed to evaluate the antioxidant and cytotoxic effects of Liza klunzingeri protein hydrolysate both in vivo and in vitro. Materials and Methods: Fish protein hydrolysate (FPH) was prepared using enzymatic hydrolysis with papain. In vitro antioxidant activity was assessed using five different antioxidant assays. The cytotoxic effect on 4T1 cell line was evaluated using the MTT assay. The distribution of the molecular weight of FPH was measured using HPLC. In the in vivo study, CCl4-exposed Wistar rats were orally treated with FPH (150, 300, and 600 mg/kg) or gallic acid (50 mg/kg) for 28 consecutive days. Results: Enzymatic hydrolysis gave hydrolysate rich in low molecular weight peptides (<1000 Da) with strong free radicals (ABTS, DPPH, and OH) scavenging activity and cytotoxicity. Treatment of CCl4-exposed rats with all doses of FPH significantly lowered serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT). FPH at doses of 300 and 600 mg/kg significantly decreased lipid peroxidation and improved total antioxidant capacity in serum, liver, and kidney of the CCl4 exposed rats. All doses of L.klunzingeri protein hydrolysate reduced CCl4-induced nitric oxide production of the kidney. Liver histopathological damage caused by CCl4 also ameliorated with all doses of FPH. Conclusion: L. klunzingeri protein hydrolysate can be considered as a functional food to alleviate oxidative stress. Keywords Author Keywords:Antioxidant activity; Cytotoxicity; Liza klunzingeri; Oxidative stress; Protein hydrolysat

Development and Validation of a Metacognitive-Cognitive-Behavioral Model for Explaining Trichotillomania

Abstract: Background & Aims: Trichotillomania (TTM) is an unknown disorder and resistant to treatment. The purpose of this study was to develop and validate the new metacognitive-cognitive-behavioral model for trichotillomania. Methods: The present study was a description and correlation study. In this study, 635 participants (304 male and 331 female) were selected. The participants completed the Massachusetts general hospital hair pulling scale (MGH-HPS), dysfunctional attitude scale (DAS), cognitive distortion scale (CDS), automatic thought questionnaire (ATQ), metacognition questionnaire (MCQ), and the obsessive-compulsive behavior scale (OCBS). For reliability assessment of the factor structure of the metacognitive-cognitive-behavioral model, the structural equation modeling analysis was used by AMOS software. Results: The results of the structural equation modeling supported a metacognitive-cognitive-behavioral model for trichotillomania. Moreover, the results showed that the model had the best fit to the data and was closely related to the theoretical assumptions. Conclusion: The model presented in this study illustrates a multidimensional approach that focuses on the metacognitive, cognitive, and behavioral dimensions; hence, the model presented in this study is a new explanatory model. This model may prompt future research into trichotillomania and facilitate clinical treatment and case formulation. Keywords: Modeling, Trichotillomania, Behavior, Cognition, Metacognitio