Tools to find scientific articles for free and legal

El movimiento Open Access o acceso abierto, tiene como propósito fundamental permitir el acceso libre, gratuito y sin restricciones a la literatura científica y académica a los investigadores. En este artículo de hablaremos de cuatro extensiones (Unpaywall, Kopernio, Open Access Button y Google Scholar Button) que se pueden instalar en los navegadores de Internet, para encontrar si existe una copia libre del artículo científico que queremos consultar, llevándonos directamente a él en muy pocos clics y ahorrándonos tiempo, dinero y energía cuando necesitamos buscar información científica.The Open Access movement, has as its fundamental purpose to allow free, unrestricted access to scientific and academic literature to researchers. In this article we will talk about four extensions (Unpaywall, Kopernio, Open Access Button and Google Scholar Button) that can be installed in Internet browsers, to find if there is a free copy of the scientific article that we want to consult, taking us directly to it in Very few clicks and saving us time, money and energy when we need to look for scientific information

Most popular applications for organizing meetings and group sessions

La pandemia de COVID-19 ha limitado enormemente la posibilidad de celebrar tanto reuniones de trabajo como actividades formativas presenciales. En el ámbito sanitario la formación es una constante y una verdadera necesidad, por eso en esta ocasión en Derm@red os mostraremos los aspectos más destacables de las aplicaciones más conocidas para organizar reuniones y sesiones formativas (videoconferencias). La elección de una u otra dependerá del tipo de actividad que necesitemos realizar.A pandemia de COVID-19 limitou enormemente a posibilidade de celebrar tanto reunións de traballo como actividades formativas presenciais. No ámbito sanitario a formación é unha constante e unha verdadeira necesidade, por iso nesta ocasión en Derm@red mostrarémosvos os aspectos máis destacables das aplicacións máis coñecidas para organizar reunións e sesións formativas (videoconferencias). A elección dunha ou doutra dependerá do tipo de actividade que necesitemos realizar

Un plan de formación de la biblioteca hospitalaria para residentes y personal sanitario

Training health personnel, researchers and residents in the different skills of bibliographic search, use of bibliographic managers or dissemination of their research is a key task in health libraries OBJETIVES: To describe and assess a library training plan in a university hospital with 400 beds, 72 residents, and a total staff of 2,330 people between specialized and primary health care. MATERIAL AND METHODS: The library offers a training plan in 3 areas 1. Continuous training for health professionals. It is the most extensive in time and topics, and agreed with the service of continuous training. Includes basic and advanced bibliographic searches, with databases such as Pubmed, Embase, Wos or specific databases of nursing, localization of clinical guides, bibliographic managers, scientific dissemination in web 2.0, new tools for presentations and posters or infographics, CVN, writing scientific articles, and repository. This regulated training is complemented by sessions in different clinical services of the hospital or health centers on demand. 2. Residents Training. An annual training plan is agreed upon with Teaching, which is currently carried out from June to January with the R1. in short sessions of 2 h, once a month and the following topics are seen: Virtual Library and its tools, Support resources for clinical decision making, Introduction to bibiographic searches and Pubmed, the Zotero bibliographic manager, Spanish search resources, CVN and Orcid. 3. Training of support to Research Committee. It is distributed over 6 “bibliopíldoras” of 45’, in two months once a week, with the following topics: Standardization of authors' and institutions' signatures, Digital identifiers of author and ORCID, Profiles of researcher: Google Scholar, Basic notions of Search, How to choose magazines to publish and Open access, creative commons licenses and repositories. Results: The different training actions are evaluated through satisfaction surveys whose results are improving over time, from 70.80% in 2015 to 92% last year, after performing corrective actions. Conclusions: 1. good reception of our training and high rates of user satisfaction 2. Assessment allows us significant improvements 3. integration of library in teaching and research committees.La formación se ha convertido en uno de las principales roles de los bibliotecarios en la actualidad. En las bibliotecas sanitarias es una tarea clave formar al personal sanitario, investigador y residentes en las diferentes habilidades de búsqueda bibliográfica, uso de gestores bibliográficos o difusión de su investigación. Objetivo: Describir y evaluar un plan de formación bibliotecario en un hospital universitario de 400 camas, 72 residentes, y una plantilla total de 2,330 personas entre especializada y primaria. Material y métodos: Desde la biblioteca se realiza formación en tres ámbitos 1.Formación Continuada del personal sanitario La más extensa en tiempo y temas, consensuada con el servicio de formación continuada. Comprende desde búsquedas bibliográficas básicas y avanzadas, con bases de datos como Pubmed, Embase, Wos o bases de datos específicas de enfermería, localización de guías clínicas, gestores bibliográficos, difusión científica en la web 2.0, nuevas herramientas para realizar presentaciones y pósteres o infografías, CVN, redacción de artículos científicos, y repositorio. Esta formación reglada se complementa con sesiones en diferentes servicios clínicos del hospital o centros de salud a demanda. 2.Formación de los Residentes Se consensúa con Docencia un plan de formación anual, que en la actualidad se realiza de junio a enero con los R1. En sesiones cortas de 2 h., una vez al mes y se ven los siguientes temas: Biblioteca Virtual y sus herramientas, Recursos de apoyo a la toma de decisiones clínicas, Iniciación a las búsquedas bibiográficas y Pubmed, el gestor bibliográfico Zotero, recursos de búsqueda en español, CVN y Orcid. 3.Formación de apoyo al Comité de Investigación Se reparte a lo largo de 6 bibliopíldoras de 45 ´, en dos meses una vez a la semana, los siguientes temas: Normalización de firmas de autores e instituciones, Identificadores digitales de autor y ORCID, Perfiles de investigador: Google Scholar, Nociones básicas de búsqueda, Cómo elegir revistas dónde publicar y Acceso abierto, licencias creative commons y repositorios. Resultados: Se evalúan las diferentes acciones formativas mediante encuestas de satisfacción, cuyos resultados van mejorando en el tiempo y con los años, al ir realizando acciones correctoras, como la duración de la formación, los horarios, las prácticas, etc. Conclusiones: 1. buena acogida de nuestra formación y altas tasas de satisfacción de los usuarios 2. la evaluación nos permite mejoras significativas 3. integración de la biblioteca en los comités de docencia e investigaciónPóster presentado en: XVI Jornadas Nacionales de Información y Documentación en Ciencias de la Salud, celebrado en Oviedo, España del 4 al 5 de abril de 2019

Variability of institutional affiliation and recovery of a hospital´s scientific output

Objetivos: analizar la variabilidad de las afiliaciones de una institución sanitaria en la base de datos Scopus y se estudió cómo influye en la recuperación de la producción científica. Métodos: se realizaron búsquedas por autores y autoras, estrategia y nombre normalizado de la institución para comparar la variabilidad de los resultados. Resultados: se constató una pérdida del 44,20 % de documentos en la recuperación por el campo de afiliación normalizada de la base de datos. Conclusiones: tras analizar las causas, se propuso varias medidas para corregir dicha pérdidaObjective: The variability of the affiliations of a health institution in the Scopus database is analyzed and how it influences the recovery of scientific production is studied. Methods: Searches were conducted by authors, strategy and standardized name of the institution to compare the variability of the results. Results: There is a loss of 44.20% of documents in the recovery by the standardized affiliation field of the database. Conclusions: After analysing the causes, a number of measures are proposed to correct this loss

Evaluación de la calidad global de la colección de guías prácticas de heridas del servicio gallego de salud

Objetivo: Evaluar el nivel de calidad global de la colección de guías prácticas de heridas del Servicio Gallego de Salud (Sergas) para la toma de decisiones clínicas. Método: Evaluación de guías basadas en la evidencia (GBP). Selección de todas las GBP que componen la colección sobre heridas publicadas por el Sergas. Valoración a través del instrumento AGREE II-GRS (Global Rating Scale). Revisión por tres experto/as. Resultados: Fueron evaluadas siete GBP: úlceras por presión, úlceras de la extremidad inferior, pie diabético, lesiones cutáneas neoplásicas, lesiones por quemadura, herida quirúrgica aguda y lesiones cutáneas asociadas a la humedad. Se evaluaron cuatro apartados: el proceso de desarrollo, el estilo de presentación, la integridad de la información y la validez clínica. Todas las GBP obtuvieron una puntuación entre 5 y 7. A nivel global se obtuvo una nota media de 6 (“calidad alta”). Conclusiones: Las GBP publicadas por el Sergas son guías de muy buena calidad, recomendables para el uso clínico y aconsejable su implementación en los procesos de toma de decisiones en el área de las úlceras y heridas.Objective: To appraise the quality global level of the collection of practical guides for wounds of the Galician Health Service (Sergas) for professional decision-making. Method: Evaluation of Best Practice Guidelines (BPG). Selection of all BPG of the collection on injuries/wounds published by Sergas. Valuation through the AGREE II-GRS instrument (Global Rating Scale). Review by three experts. Results: Seven BPG were evaluated: pressure ulcers, ulcers of the lower limb, diabetic foot, skin tumor lesions, burn injuries, acute surgical wound and skin lesions associated with humidity. Four sections were evaluated: the development process, the presentation style, the integrity of the information and the clinical validity. All the GBP obtained a score between 5 and 7. On a global level, an average score of 6 was obtained (High quality). Conclusions: The BPG published by Sergas are guides of very good quality, recommended for clinical use and advisable to implement them in decision-making processes in the area of ulcers and wounds

Association of Candidate Gene Polymorphisms With Chronic Kidney Disease: Results of a Case-Control Analysis in the Nefrona Cohort

Chronic kidney disease (CKD) is a major risk factor for end-stage renal disease, cardiovascular disease and premature death. Despite classical clinical risk factors for CKD and some genetic risk factors have been identified, the residual risk observed in prediction models is still high. Therefore, new risk factors need to be identified in order to better predict the risk of CKD in the population. Here, we analyzed the genetic association of 79 SNPs of proteins associated with mineral metabolism disturbances with CKD in a cohort that includes 2, 445 CKD cases and 559 controls. Genotyping was performed with matrix assisted laser desorption ionizationtime of flight mass spectrometry. We used logistic regression models considering different genetic inheritance models to assess the association of the SNPs with the prevalence of CKD, adjusting for known risk factors. Eight SNPs (rs1126616, rs35068180, rs2238135, rs1800247, rs385564, rs4236, rs2248359, and rs1564858) were associated with CKD even after adjusting by sex, age and race. A model containing five of these SNPs (rs1126616, rs35068180, rs1800247, rs4236, and rs2248359), diabetes and hypertension showed better performance than models considering only clinical risk factors, significantly increasing the area under the curve of the model without polymorphisms. Furthermore, one of the SNPs (the rs2248359) showed an interaction with hypertension, being the risk genotype affecting only hypertensive patients. We conclude that 5 SNPs related to proteins implicated in mineral metabolism disturbances (Osteopontin, osteocalcin, matrix gla protein, matrix metalloprotease 3 and 24 hydroxylase) are associated to an increased risk of suffering CKD

Advances in the subseasonal prediction of extreme events: relevant case studies across the globe

Extreme weather events have devastating impacts on human health, economic activities, ecosysytems, and infrastructure. It is therefore crucial to anticipate extremes and their impacts to allow for preparedness and emergency measures. There is indeed potential for probabilistic subseasonal prediction on timescales of several weeks for many extreme events. Here we provide an overview of subseasonal predictability for case studies of some of the most prominent extreme events across the globe using the ECMWF S2S prediction system: heatwaves, cold spells, heavy precipitation events, and tropical and extratropical cyclones. The considered heatwaves exhibit predictability on timescales of 3-4 weeks, while this timescale is 2-3 weeks for cold spells. Precipitation extremes are the least predictable among the considered case studies. Tropical cyclones, on the other hand, can exhibit probabilistic predictability on timescales of up to 3 weeks, which in the presented cases was aided by remote precursors such as the Madden-Julian Oscillation. For extratropical cyclones, lead times are found to be shorter. These case studies clearly illustrate the potential for event - dependent advance warnings for a wide range of extreme events. The subseasonal predictability of extreme events demonstrated here allows for an extension of warning horizons, provides advance information to impact modelers, and informs communities and stakeholders affected by the impacts of extreme weather events

Hypothalamic κ-Opioid Receptor Modulates the Orexigenic Effect of Ghrelin

The opioid system is well recognized as an important regulator of appetite and energy balance. We now hypothesized that the hypothalamic opioid system might modulate the orexigenic effect of ghrelin. Using pharmacological and gene silencing approaches, we demonstrate that ghrelin utilizes a hypothalamic κ-opioid receptor (KOR) pathway to increase food intake in rats. Pharmacological blockade of KOR decreases the acute orexigenic effect of ghrelin. Inhibition of KOR expression in the hypothalamic arcuate nucleus is sufficient to blunt ghrelin-induced food intake. By contrast, the specific inhibition of KOR expression in the ventral tegmental area does not affect central ghrelin-induced feeding. This new pathway is independent of ghrelin-induced AMP-activated protein kinase activation, but modulates the levels of the transcription factors and orexigenic neuropeptides triggered by ghrelin to finally stimulate feeding. Our novel data implicate hypothalamic KOR signaling in the orexigenic action of ghrelin

Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries

Background Anastomotic leak affects 8 per cent of patients after right colectomy with a 10-fold increased risk of postoperative death. The EAGLE study aimed to develop and test whether an international, standardized quality improvement intervention could reduce anastomotic leaks. Methods The internationally intended protocol, iteratively co-developed by a multistage Delphi process, comprised an online educational module introducing risk stratification, an intraoperative checklist, and harmonized surgical techniques. Clusters (hospital teams) were randomized to one of three arms with varied sequences of intervention/data collection by a derived stepped-wedge batch design (at least 18 hospital teams per batch). Patients were blinded to the study allocation. Low- and middle-income country enrolment was encouraged. The primary outcome (assessed by intention to treat) was anastomotic leak rate, and subgroup analyses by module completion (at least 80 per cent of surgeons, high engagement; less than 50 per cent, low engagement) were preplanned. Results A total 355 hospital teams registered, with 332 from 64 countries (39.2 per cent low and middle income) included in the final analysis. The online modules were completed by half of the surgeons (2143 of 4411). The primary analysis included 3039 of the 3268 patients recruited (206 patients had no anastomosis and 23 were lost to follow-up), with anastomotic leaks arising before and after the intervention in 10.1 and 9.6 per cent respectively (adjusted OR 0.87, 95 per cent c.i. 0.59 to 1.30; P = 0.498). The proportion of surgeons completing the educational modules was an influence: the leak rate decreased from 12.2 per cent (61 of 500) before intervention to 5.1 per cent (24 of 473) after intervention in high-engagement centres (adjusted OR 0.36, 0.20 to 0.64; P < 0.001), but this was not observed in low-engagement hospitals (8.3 per cent (59 of 714) and 13.8 per cent (61 of 443) respectively; adjusted OR 2.09, 1.31 to 3.31). Conclusion Completion of globally available digital training by engaged teams can alter anastomotic leak rates. Registration number: NCT04270721 (http://www.clinicaltrials.gov)