319 research outputs found
Investigating the Antimicrobial Properties of Cannabinoid Compounds
As bacteria are rapidly developing resistance against existing drugs, cannabinoids present a novel and exciting opportunity as a potential new source of antibiotics. Cannabinoid compounds have become an epicenter of research in recent years with numerous studies elucidating the therapeutic uses of a few of the numerous compounds such as Cannabidiol (CBD) and Cannabigerol (CBG). This study seeks to investigate the antimicrobial properties of these two aforementioned compounds on a number of gram-negative and gram-positive microbes such as Candida albicans, Streptococcus pyogenes and Pseudomonas aeruginosa. Using spread plating methods, various concentrations and mixtures of CBD and CBG were applied to selected microbes in order to observe the effects (if any) on colony formation. Initial results have indicated a strong effect on gram-positive organisms and little to no effect on gram-negative organisms. These early results corroborate published literature reports. Ongoing work includes an investigation into the lipopolysaccharide (LPS) layer found on the gram-negative bacteria. Through enzymatic treatment, LPS layer removal will be facilitated, and testing performed to determine the role this layer plays in the observed decreased antimicrobial activity of these organisms
Investigating the Antimicrobial Properties of Cannabinoid Compounds
As bacteria are rapidly developing resistance against existing drugs, cannabinoids present a novel and exciting opportunity as a potential new source of antibiotics. Cannabinoid compounds have become an epicenter of research in recent years with numerous studies elucidating the therapeutic uses of a few of the numerous compounds such as Cannabidiol (CBD) and Cannabigerol (CBG). This study seeks to investigate the antimicrobial properties of these two aforementioned compounds on a number of gram-negative and gram-positive microbes such as Candida albicans, Streptococcus pyogenes and Pseudomonas aeruginosa. Using spread plating methods, various concentrations and mixtures of CBD and CBG were applied to selected microbes in order to observe the effects (if any) on colony formation. Initial results have indicated a strong effect on gram-positive organisms and little to no effect on gram-negative organisms. These early results corroborate published literature reports. Ongoing work includes an investigation into the lipopolysaccharide (LPS) layer found on the gram-negative bacteria. Through enzymatic treatment, LPS layer removal will be facilitated, and testing performed to determine the role this layer plays in the observed decreased antimicrobial activity of these organisms
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Medium energy measurements of N-N parameters
This paper discusses the following topics: pp elastic absolute cross section measurement; spin transfer measurements in np elastic scattering; single pion production in np scattering; photoproduction of high P{sub t} jets in the wide band beam of the tevatron; and search for K{sub L}{sup 0} {yields} {mu}e, K{sub L}{sup 0} {yields} ee
Measuring movement fluency during the sit-to-walk task
Restoring movement fluency is a key focus for physical rehabilitation; it's measurement, however, lacks objectivity. The purpose of this study was to find whether measurable movement fluency variables differed between groups of adults with different movement abilities whilst performing the sit-to-walk (STW) movement. The movement fluency variables were: (1) hesitation during movement (reduction in forward velocity of the centre of mass; CoM), (2) coordination (percentage of temporal overlap of joint rotations) and (3) smoothness (number of inflections in the CoM jerk signal)
Description of superdeformed nuclei in the interacting boson model
The interacting boson model is extended to describe the spectroscopy of
superdeformed bands. Microscopic structure of the model in the second minimum
is discussed and superdeformed bosons are introduced as the new building
blocks. Solutions of a quadrupole Hamiltonian are implemented through the
expansion method. Effects of the quadrupole parameters on dynamic moment of
inertia and electric quadrupole transition rates are discussed and the results
are used in a description of superdeformed bands in the Hg-Pb and Gd-Dy
regions.Comment: 18 pages revtex, 9 figures available upon reques
Effect of Solar Wind Drag on the Determination of the Properties of Coronal Mass Ejections from Heliospheric Images
The Fixed-\Phi (F\Phi) and Harmonic Mean (HM) fitting methods are two methods
to determine the average direction and velocity of coronal mass ejections
(CMEs) from time-elongation tracks produced by Heliospheric Imagers (HIs), such
as the HIs onboard the STEREO spacecraft. Both methods assume a constant
velocity in their descriptions of the time-elongation profiles of CMEs, which
are used to fit the observed time-elongation data. Here, we analyze the effect
of aerodynamic drag on CMEs propagating through interplanetary space, and how
this drag affects the result of the F\Phi and HM fitting methods. A simple drag
model is used to analytically construct time-elongation profiles which are then
fitted with the two methods. It is found that higher angles and velocities give
rise to greater error in both methods, reaching errors in the direction of
propagation of up to 15 deg and 30 deg for the F\Phi and HM fitting methods,
respectively. This is due to the physical accelerations of the CMEs being
interpreted as geometrical accelerations by the fitting methods. Because of the
geometrical definition of the HM fitting method, it is affected by the
acceleration more greatly than the F\Phi fitting method. Overall, we find that
both techniques overestimate the initial (and final) velocity and direction for
fast CMEs propagating beyond 90 deg from the Sun-spacecraft line, meaning that
arrival times at 1 AU would be predicted early (by up to 12 hours). We also
find that the direction and arrival time of a wide and decelerating CME can be
better reproduced by the F\Phi due to the cancellation of two errors:
neglecting the CME width and neglecting the CME deceleration. Overall, the
inaccuracies of the two fitting methods are expected to play an important role
in the prediction of CME hit and arrival times as we head towards solar maximum
and the STEREO spacecraft further move behind the Sun.Comment: Solar Physics, Online First, 17 page
A Compact Beam Stop for a Rare Kaon Decay Experiment
We describe the development and testing of a novel beam stop for use in a
rare kaon decay experiment at the Brookhaven AGS. The beam stop is located
inside a dipole spectrometer magnet in close proximity to straw drift chambers
and intercepts a high-intensity neutral hadron beam. The design process,
involving both Monte Carlo simulations and beam tests of alternative beam-stop
shielding arrangements, had the goal of minimizing the leakage of particles
from the beam stop and the resulting hit rates in detectors, while preserving
maximum acceptance for events of interest. The beam tests consisted of
measurements of rates in drift chambers, scintilation counter hodoscopes, a gas
threshold Cherenkov counter, and a lead glass array. Measurements were also
made with a set of specialized detectors which were sensitive to low-energy
neutrons, photons, and charged particles. Comparisons are made between these
measurements and a detailed Monte Carlo simulation.Comment: 39 pages, 14 figures, submitted to Nuclear Instruments and Method
A straw drift chamber spectrometer for studies of rare kaon decays
We describe the design, construction, readout, tests, and performance of
planar drift chambers, based on 5 mm diameter copperized Mylar and Kapton
straws, used in an experimental search for rare kaon decays. The experiment
took place in the high-intensity neutral beam at the Alternating Gradient
Synchrotron of Brookhaven National Laboratory, using a neutral beam stop, two
analyzing dipoles, and redundant particle identification to remove backgrounds
Microscopic Structure of High-Spin Vibrational Excitations in Superdeformed 190,192,194Hg
Microscopic RPA calculations based on the cranked shell model are performed
to investigate the quadrupole and octupole correlations for excited
superdeformed bands in 190Hg, 192Hg, and 194Hg. The K=2 octupole vibrations are
predicted to be the lowest excitation modes at zero rotational frequency. At
finite frequency, however, the interplay between rotation and vibrations
produces different effects depending on neutron number: The lowest octupole
phonon is rotationally aligned in 190Hg, is crossed by the aligned
two-quasiparticle bands in 192Hg, and retains the K=2 octupole vibrational
character up to the highest frequency in 194Hg. The gamma vibrations are
predicted to be higher in energy and less collective than the octupole
vibrations. From a comparison with the experimental dynamic moments of inertia,
a new interpretation of the observed excited bands invoking the K=2 octupole
vibrations is proposed, which suggests those octupole vibrations may be
prevalent in SD Hg nuclei.Comment: 22 pages, REVTeX, 12 postscript figures are available on reques
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