499 research outputs found
Prospective Randomized Trial Comparing Endoscopic Sphincterotomy Followed by Surgery with Surgery Alone in Good Risk Patients with Choledocholithiasis
Background: Role of endoscopic sphincterotomy (ES) in high risk patients with choledocholithiasis is established but its role in good risk patients is unclear
Unusual Tumors Causing Extrahepatic Portal Venous Obstruction
Extrahepatic portal vein obstruction has been reported to be associated with tumors of liver, bile ducts and pancreas. We report two cases, one with gastric leiomyosarcoma and another with Non Hodgkin’s
lymphoma, complicated by portal vein block and presenting with gastric variceal bleeding. Portal vein
block in both cases was due to direct vascular infiltration. Development of portal hypertension posed
difficulties in management
Thromboinflammatory changes in plasma proteome of pregnant women with PCOS detected by quantitative label-free proteomics
Polycystic ovary syndrome (PCOS) is the most common endocrinological disorder of fertile-aged women. Several adverse pregnancy outcomes and abnormalities of the placenta have been associated with PCOS. By using quantitative label-free proteomics we investigated whether changes in the plasma proteome of pregnant women with PCOS could elucidate the mechanisms behind the pathologies observed in PCOS pregnancies. A total of 169 proteins with >= 2 unique peptides were detected to be differentially expressed between women with PCOS (n = 7) and matched controls (n = 20) at term of pregnancy, out of which 35 were significant (p-value <0.05). A pathway analysis revealed that networks related to humoral immune responses, inflammatory responses, cardiovascular disease and cellular growth and proliferation were affected by PCOS. Classification of cases and controls was carried out using principal component analysis, orthogonal projections on latent structure-discriminant analysis (OPLS-DA), hierarchical clustering, self-organising maps and ROC-curve analysis. The most significantly enriched proteins in PCOS were properdin and insulin-like growth factor II. In the dataset, properdin had the best predictive accuracy for PCOS (AUC=1). Additionally, properdin abundances correlated with AMH levels in pregnant women.Peer reviewe
A satellite-borne experiment to study the fifth force
An experiment with a satellite-borne torsion balance capable of measuring the fifth force which couples to baryon number or lepton number with a strengtr gravity and range ~109 cm is described
Concurrent and Reactive Constraint Programming
The Italian Logic Programming community has given several contributions to the theory of Concurrent Constraint Programming. In particular, in the topics of semantics, verification, and timed extensions. In this paper we review the main lines of research and contributions of the community in this fiel
Enhancing hole mobility in III-V semiconductors
Transistors based on III-V semiconductor materials have been used for a
variety of analog and high frequency applications driven by the high electron
mobilities in III-V materials. On the other hand, the hole mobility in III-V
materials has always lagged compared to group-IV semiconductors such as silicon
and germanium. In this paper we explore the used of strain and heterostructure
design guided by bandstructure modeling to enhance the hole mobility in III-V
materials. Parameters such as strain, valence band offset, effective masses and
splitting between the light and heavy hole bands that are important for
optimizing hole transport are measured quantitatively using various
experimental techniques. A peak Hall mobility for the holes of 960cm2/Vs is
demonstrated and the high hole mobility is maintained even at high sheet
charge.Comment: 18 pages, 21 figure
Physics at a 100 TeV pp collider: beyond the Standard Model phenomena
This report summarises the physics opportunities in the search and study of
physics beyond the Standard Model at a 100 TeV pp collider.Comment: 196 pages, 114 figures. Chapter 3 of the "Physics at the FCC-hh"
Repor
Excess Higgs Production in Neutralino Decays
The ATLAS and CMS experiments have recently claimed discovery of a Higgs
boson-like particle at ~5 sigma confidence and are beginning to test the
Standard Model predictions for its production and decay. In a variety of
supersymmetric models, a neutralino NLSP can decay dominantly to the Higgs and
the LSP. In natural SUSY models, a light third generation squark decaying
through this chain can lead to large excess Higgs production while evading
existing BSM searches. Such models can be observed at the 8 TeV LHC in channels
exploiting the rare diphoton decays of the Higgs produced in the cascade decay.
Identifying a diphoton resonance in association with missing energy, a lepton,
or b-tagged jets is a promising search strategy for discovery of these models,
and would immediately signal new physics involving production of a Higgs boson.
We also discuss the possibility that excess Higgs production in these SUSY
decays can be responsible for enhancements of up to 50% over the SM prediction
for the observed rate in the existing inclusive diphoton searches, a scenario
which would likely by the end of the 8 TeV run be accompanied by excesses in
the diphoton + lepton/MET and SUSY multi-lepton/b searches and a potential
discovery in a diphoton + 2b search.Comment: 42 pages, 19 figure
Virtual Machine Support for Many-Core Architectures: Decoupling Abstract from Concrete Concurrency Models
The upcoming many-core architectures require software developers to exploit
concurrency to utilize available computational power. Today's high-level
language virtual machines (VMs), which are a cornerstone of software
development, do not provide sufficient abstraction for concurrency concepts. We
analyze concrete and abstract concurrency models and identify the challenges
they impose for VMs. To provide sufficient concurrency support in VMs, we
propose to integrate concurrency operations into VM instruction sets.
Since there will always be VMs optimized for special purposes, our goal is to
develop a methodology to design instruction sets with concurrency support.
Therefore, we also propose a list of trade-offs that have to be investigated to
advise the design of such instruction sets.
As a first experiment, we implemented one instruction set extension for
shared memory and one for non-shared memory concurrency. From our experimental
results, we derived a list of requirements for a full-grown experimental
environment for further research
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