ALMA constraints on the faint millimetre source number counts and their contribution to the cosmic infrared background

We have analysed 18 ALMA continuum maps in Bands 6 and 7, with rms down to 7.8$\mu$Jy, to derive differential number counts down to 60$\mu$Jy and 100$\mu$Jy at $\lambda=$1.3 mm and $\lambda=$1.1 mm, respectively. The area covered by the combined fields is $\rm 9.5\times10^{-4}deg^2$ at 1.1mm and $\rm 6.6\times10^{-4}deg^{2}$ at 1.3mm. We improved the source extraction method by requiring that the dimension of the detected sources be consistent with the beam size. This method enabled us to remove spurious detections that have plagued the purity of the catalogues in previous studies. We detected 50 faint sources with S/N$>$3.5 down to 60$\mu$Jy, hence improving the statistics by a factor of four relative to previous studies. The inferred differential number counts are $\rm dN/d(Log_{10}S)=1\times10^5~deg^2$ at a 1.1 mm flux $S_{\lambda = 1.1~mm} = 130~\mu$Jy, and $\rm dN/d(Log_{10}S)=1.1\times10^5~deg^2$ at a 1.3 mm flux $\rm S_{\lambda = 1.3~mm} = 60~\mu$Jy. At the faintest flux limits, i.e. 30$\mu$Jy and 40$\mu$Jy, we obtain upper limits on the differential number counts of $\rm dN/d(Log_{10}S) < 7\times10^5~deg^2$ and $\rm dN/d(Log_{10}S)<3\times10^5~deg^2$, respectively. Our results provide a new lower limit to CIB intensity of 17.2${\rm Jy\ deg^{-2}}$ at 1.1mm and of 12.9${\rm Jy\ deg^{-2}}$ at 1.3mm. Moreover, the flattening of the integrated number counts at faint fluxes strongly suggests that we are probably close to the CIB intensity. Our data imply that galaxies with SFR$<40~M_{\odot}/yr$ certainly contribute less than 50% to the CIB while more than 50% of the CIB must be produced by galaxies with $\rm SFR>40~M_{\odot}/yr$. The differential number counts are in nice agreement with recent semi-analytical models of galaxy formation even as low as our faint fluxes. Consequently, this supports the galaxy evolutionary scenarios and assumptions made in these models.Comment: 11 pages, 9 figures, A&A accepte

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Elucidating glycosaminoglycan–protein–protein interactions using carbohydrate microarray and computational approaches

Glycosaminoglycan polysaccharides play critical roles in many cellular processes, ranging from viral invasion and angiogenesis to spinal cord injury. Their diverse biological activities are derived from an ability to regulate a remarkable number of proteins. However, few methods exist for the rapid identification of glycosaminoglycan–protein interactions and for studying the potential of glycosaminoglycans to assemble multimeric protein complexes. Here, we report a multidisciplinary approach that combines new carbohydrate microarray and computational modeling methodologies to elucidate glycosaminoglycan–protein interactions. The approach was validated through the study of known protein partners for heparan and chondroitin sulfate, including fibroblast growth factor 2 (FGF2) and its receptor FGFR1, the malarial protein VAR2CSA, and tumor necrosis factor-α (TNF-α). We also applied the approach to identify previously undescribed interactions between a specific sulfated epitope on chondroitin sulfate, CS-E, and the neurotrophins, a critical family of growth factors involved in the development, maintenance, and survival of the vertebrate nervous system. Our studies show for the first time that CS is capable of assembling multimeric signaling complexes and modulating neurotrophin signaling pathways. In addition, we identify a contiguous CS-E-binding site by computational modeling that suggests a potential mechanism to explain how CS may promote neurotrophin-tyrosine receptor kinase (Trk) complex formation and neurotrophin signaling. Together, our combined microarray and computational modeling methodologies provide a general, facile means to identify new glycosaminoglycan–protein–protein interactions, as well as a molecular-level understanding of those complexes

MASCOT: an ESO-ARO legacy survey of molecular gas in nearby SDSS-MaNGA galaxies - I. First data release, and global and resolved relations between H<inf>2</inf>and stellar content

We present the first data release of the MaNGA-ARO Survey of CO Targets (MASCOT), an ESO Public Spectroscopic Survey conducted at the Arizona Radio Observatory (ARO). We measure the CO(1-0) line emission in a sample of 187 nearby galaxies selected from the Mapping Nearby Galaxies at Apache Point Observatory (MaNGA) survey that has obtained integral field unit (IFU) spectroscopy for a sample of ~ 10,000 galaxies at low redshift. The main goal of MASCOT is to probe the molecular gas content of star-forming galaxies with stellar masses > 10^9.5 M_solar and with associated MaNGA IFU observations and well-constrained quantities like stellar masses, star formation rates and metallicities. In this paper we present the first results of the MASCOT survey, providing integrated CO(1-0) measurements that cover several effective radii of the galaxy and present CO luminosities, CO kinematics, and estimated H2 gas masses. We observe that the decline of galaxy star formation rate with respect to the star formation main sequence (SFMS) increases with the decrease of molecular gas and with a reduced star formation efficiency, in agreement with results of other integrated studies. Relating the molecular gas mass fractions with the slope of the stellar age gradients inferred from the MaNGA observations, we find that galaxies with lower molecular gas mass fractions tend to show older stellar populations close to the galactic center, while the opposite is true for galaxies with higher molecular gas mass fractions, providing tentative evidence for inside-out quenching

ALMaQUEST. IV. The ALMA-MaNGA QUEnching and STar Formation (ALMaQUEST) Survey

The ALMaQUEST (ALMA-MaNGA QUEnching and STar formation) survey is a program with spatially-resolved $^{12}$CO(1-0) measurements obtained with the Atacama Large Millimeter Array (ALMA) for 46 galaxies selected from the Mapping Nearby Galaxies at Apache Point Observatory (MaNGA) DR15 optical integral-field spectroscopic survey. The aim of the ALMaQUEST survey is to investigate the dependence of star formation activity on the cold molecular gas content at kpc scales in nearby galaxies. The sample consists of galaxies spanning a wide range in specific star formation rate (sSFR), including starburst (SB), main-sequence (MS), and green valley (GV) galaxies. In this paper, we present the sample selection and characteristics of the ALMA observations, and showcase some of the key results enabled by the combination of spatially-matched stellar populations and gas measurements. Considering the global (aperture-matched) stellar mass, molecular gas mass, and star formation rate of the sample, we find that the sSFR depends on both the star formation efficiency (SFE) and the molecular gas fraction ($f_{\rm H_{2}}$), although the correlation with the latter is slightly weaker. Furthermore, the dependence of sSFR on the molecular gas content (SFE or $f_{\rm H_{2}}$) is stronger than that on either the atomic gas fraction or the molecular-to-atomic gas fraction, albeit with the small HI sample size. On kpc scales, the variations in both SFE and $f_{\rm H_{2}}$ within individual galaxies can be as large as 1-2 dex thereby demonstrating that the availability of spatially-resolved observations is essential to understand the details of both star formation and quenching processes.STFC ER

The Rest-Frame Submillimeter Spectrum of High-Redshift, Dusty, Star-Forming Galaxies

We present the average rest-frame spectrum of high-redshift dusty, star-forming galaxies from 250-770GHz. This spectrum was constructed by stacking ALMA 3mm spectra of 22 such sources discovered by the South Pole Telescope and spanning z=2.0-5.7. In addition to multiple bright spectral features of 12CO, [CI], and H2O, we also detect several faint transitions of 13CO, HCN, HNC, HCO+, and CN, and use the observed line strengths to characterize the typical properties of the interstellar medium of these high-redshift starburst galaxies. We find that the 13CO brightness in these objects is comparable to that of the only other z>2 star-forming galaxy in which 13CO has been observed. We show that the emission from the high-critical density molecules HCN, HNC, HCO+, and CN is consistent with a warm, dense medium with T_kin ~ 55K and n_H2 >~ 10^5.5 cm^-3. High molecular hydrogen densities are required to reproduce the observed line ratios, and we demonstrate that alternatives to purely collisional excitation are unlikely to be significant for the bulk of these systems. We quantify the average emission from several species with no individually detected transitions, and find emission from the hydride CH and the linear molecule CCH for the first time at high redshift, indicating that these molecules may be powerful probes of interstellar chemistry in high-redshift systems. These observations represent the first constraints on many molecular species with rest-frame transitions from 0.4-1.2mm in star-forming systems at high redshift, and will be invaluable in making effective use of ALMA in full science operations.Comment: 19 pages, 10 figures (2 in appendices); accepted for publication in Ap

Extragalactic millimeter-wave point source catalog, number counts and statistics from 771 square degrees of the SPT-SZ Survey

We present a point source catalog from 771 square degrees of the South Pole Telescope Sunyaev Zel'dovich (SPT-SZ) survey at 95, 150, and 220 GHz. We detect 1545 sources above 4.5 sigma significance in at least one band. Based on their relative brightness between survey bands, we classify the sources into two populations, one dominated by synchrotron emission from active galactic nuclei, and one dominated by thermal emission from dust-enshrouded star-forming galaxies. We find 1238 synchrotron and 307 dusty sources. We cross-match all sources against external catalogs and find 189 unidentified synchrotron sources and 189 unidentified dusty sources. The dusty sources without counterparts are good candidates for high-redshift, strongly lensed submillimeter galaxies. We derive number counts for each population from 1 Jy down to roughly 9, 5, and 11 mJy at 95, 150, and 220 GHz. We compare these counts with galaxy population models and find that none of the models we consider for either population provide a good fit to the measured counts in all three bands. The disparities imply that these measurements will be an important input to the next generation of millimeter-wave extragalactic source population models.Comment: 23 pages, 8 figures, submitted to Ap