223 research outputs found
Breast treatments with Axxent equipment.Comparison with Mammosite for skin, lung and heart dose
Poster Session [EP-1314]
Purpose or Objective We have treated 250 patients at our center from May 2015 to September 2017 for breast cancer with Axxent (Xoft Inc.) intraoperativ e radiotherapy (IORT) following the inclusion parameters of the TARGIT study, in this work we compare the doses in the skin of the first 150 patients treated with the 50 kVp source with the skin doses they would have received using the Mammosite kit using an Ir192 source. Material and Methods To the 250 patients treated in our center after removing the tumor, the appropriate balloon size is chosen to cover the tumor area with a dose of 20 Gy on the ball oon surface, the sizes used range fro m 30-65 cm3, after which it is verified that the distance to skin from the 3 closest points of the balloon i s less than 10 mm and then the treatment is carried out with an average duration of 10.3 minutes being the volumes of 30 and 35 cm3 the most used due to the inclusion criteria of the procedure. Treatment plans are previously per formed in a Brachyvision treatment planning system (TPS) (Varian Inc.) for each of the possible volumes. In tur n, another plan is calculated with the Mammosite applicator and Ir192 source, from which the skin dose of each control point is estimated, compared to our results. We present also the cases of acute dermatitis seen for these first 150 patients in a time less than 6 months after the surgical act and irradiation. Results The differences in maximum skin dose for bot h types of treatment are 8.1 ± 1.2 Gy for the case of Mammosite and 5.7 ± 1.5 Gy for patients treated with electronic source, due to the difference in the depht dos e percentage of both types of treatment (Image 1). This, in turn, explains the very few cases of acute dermatitis at 6 months (8 cases of grade 2 and 2 cases of grade 3) (Image 2) with no recurrence to date.We also show the mean and maximum doses (expressed as percentage of prescribed dose) for the left lung and heart in cases of left breast tumor for the volumes of 30 and 35 cm3, which are the most common volumes in our hospital (70% of cases):
LEFT LUNG (Left Breast tratment) AXXENT MAMMOSITE
Maximun Dose (%PD) 20.4% 29.9%
Mean Dose (%PD) 1.0% 3.9%
HEART (Left Breast tratment) AXXENT MAMMOSITE
Maximun Dose (%PD) 4.1% 10.4%
Mean Dose (%PD) 0.8% 3.3%
Conclusion It is concluded that the IORT treatments performed with the Axxent equipment with electronic source are a good alternative to those performed with Ir192 and our 250 patients treated to date to the good results presented by other centers are joined.In additi on to the low skin toxicity, there is no recurrence in patients treated so far, which makes us very optimistic about the results
Matter flows around black holes and gravitational radiation
We develop and calibrate a new method for estimating the gravitational
radiation emitted by complex motions of matter sources in the vicinity of black
holes. We compute numerically the linearized curvature perturbations induced by
matter fields evolving in fixed black hole backgrounds, whose evolution we
obtain using the equations of relativistic hydrodynamics. The current
implementation of the proposal concerns non-rotating holes and axisymmetric
hydrodynamical motions. As first applications we study i) dust shells falling
onto the black hole isotropically from finite distance, ii) initially spherical
layers of material falling onto a moving black hole, and iii) anisotropic
collapse of shells. We focus on the dependence of the total gravitational wave
energy emission on the flow parameters, in particular shell thickness, velocity
and degree of anisotropy. The gradual excitation of the black hole quasi-normal
mode frequency by sufficiently compact shells is demonstrated and discussed. A
new prescription for generating physically reasonable initial data is
discussed, along with a range of technical issues relevant to numerical
relativity.Comment: 27 pages, 12 encapsulated figures, revtex, amsfonts, submitted to
Phys. Rev.
The Gaugino Code
Gauginos might play a crucial role in the search for supersymmetry at the
Large Hadron Collider (LHC). Mass predictions for gauginos are rather robust
and often related to the values of the gauge couplings. We analyse the ratios
of gaugino masses in the LHC energy range for various schemes of supersymmetry
breakdown and mediation. Three distinct mass patterns emerge.Comment: 42 pages, Latex; a discussion of deflected anomaly mediation added,
references adde
Numerical Relativity: A review
Computer simulations are enabling researchers to investigate systems which
are extremely difficult to handle analytically. In the particular case of
General Relativity, numerical models have proved extremely valuable for
investigations of strong field scenarios and been crucial to reveal unexpected
phenomena. Considerable efforts are being spent to simulate astrophysically
relevant simulations, understand different aspects of the theory and even
provide insights in the search for a quantum theory of gravity. In the present
article I review the present status of the field of Numerical Relativity,
describe the techniques most commonly used and discuss open problems and (some)
future prospects.Comment: 2 References added; 1 corrected. 67 pages. To appear in Classical and
Quantum Gravity. (uses iopart.cls
Twenty Years of SUGRA
A brief review is given of the developments of mSUGRA and its extensions
since the formulation of these models in 1982. Future directions and prospects
are also discussed.Comment: Invited talk at the International Conference BEYOND-2003, Schloss
Ringberg, Germany, June 10-14, 2003; 21 pages, Late
Yukawa Unified Supersymmetric SO(10) Model: Cosmology, Rare Decays and Collider Searches
It has recently been pointed out that viable sparticle mass spectra can be
generated in Yukawa unified SO(10) supersymmetric grand unified models
consistent with radiative breaking of electroweak symmetry. Model solutions are
obtained only if , and positive -term
contributions to scalar masses from SO(10) gauge symmetry breaking are used. In
this paper, we attempt to systematize the parameter space regions where
solutions are obtained. We go on to calculate the relic density of neutralinos
as a function of parameter space. No regions of the parameter space explored
were actually cosmologically excluded, and very reasonable relic densities were
found in much of parameter space. Direct neutralino detection rates could
exceed 1 event/kg/day for a Ge detector, for low values of GUT scale
gaugino mass . We also calculate the branching fraction for decays, and find that it is beyond the 95% CL experimental limits in
much, but not all, of the parameter space regions explored. However, recent
claims have been made that NLO effects can reverse the signs of certain
amplitudes in the calculation, leading to agreement between
theory and experiment in Yukawa unified SUSY models. For the Fermilab Tevatron
collider, significant regions of parameter space can be explored via
and searches. There also exist some limited regions of
parameter space where a trilepton signal can be seen at TeV33. Finally, there
exist significant regions of parameter space where direct detection of bottom
squark pair production can be made, especially for large negative values of the
GUT parameter .Comment: Added comparison to Blazek/Raby results and added Comments on de Boer
et al. b->s gamma result
de Sitter String Vacua from Supersymmetric D-terms
We propose a new mechanism for obtaining de Sitter vacua in type IIB string
theory compactified on (orientifolded) Calabi-Yau manifolds similar to those
recently studied by Kachru, Kallosh, Linde and Trivedi (KKLT). dS vacuum
appears in KKLT model after uplifting an AdS vacuum by adding an anti-D3-brane,
which explicitly breaks supersymmetry. We accomplish the same goal by adding
fluxes of gauge fields within the D7-branes, which induce a D-term potential in
the effective 4D action. In this way we obtain dS space as a spontaneously
broken vacuum from a purely supersymmetric 4D action. We argue that our
approach can be directly extended to heterotic string vacua, with the dilaton
potential obtained from a combination of gaugino condensation and the D-terms
generated by anomalous U(1) gauge groups.Comment: 17 pages, 1 figur
VEGAS: A VST Early-type GAlaxy Survey. II. Photometric study of giant ellipticals and their stellar halos
Observations of diffuse starlight in the outskirts of galaxies are thought to
be a fundamental source of constraints on the cosmological context of galaxy
assembly in the CDM model. Such observations are not trivial because
of the extreme faintness of such regions. In this work, we investigate the
photometric properties of six massive early type galaxies (ETGs) in the VEGAS
sample (NGC 1399, NGC 3923, NGC 4365, NGC 4472, NGC 5044, and NGC 5846) out to
extremely low surface brightness levels, with the goal of characterizing the
global structure of their light profiles for comparison to state-of-the-art
galaxy formation models. We carry out deep and detailed photometric mapping of
our ETG sample taking advantage of deep imaging with VST/OmegaCAM in the g and
i bands. By fitting the light profiles, and comparing the results to
simulations of elliptical galaxy assembly, we identify signatures of a
transition between "relaxed" and "unrelaxed" accreted components and can
constrain the balance between in situ and accreted stars. The very good
agreement of our results with predictions from theoretical simulations
demonstrates that the full VEGAS sample of ETGs will allow us to use
the distribution of diffuse light as a robust statistical probe of the
hierarchical assembly of massive galaxies.Comment: Accepted for publication in Astronomy & Astrophysic
The role of the land-surface model for climate change projections over the Iberian Peninsula
The importance of land-surface processes within Regional Climate Models for accurately reproducing the present-day climate is well known. However, their role when projecting future climate is still poorly reported. Hence, this work assesses the influence of the land-surface processes, particularly the contribution of soil moisture, when projecting future changes for temperature, precipitation and wind over a complex area as the Iberian Peninsula, which, in addition, shows great sensitivity to climate change. The main signals are found for the summer season, when the results indicate a strengthening in the increases projected for both mean temperature and temperature variability as a consequence of the future intensification of the positive soil moisture-temperature feedback. The more severe warming over the inner dry Iberian Peninsula further implies an intensification of the Iberian thermal low and, thus, of the cyclonic circulation. Furthermore, the land-atmosphere coupling leads to the projection of a wider future daily temperature range, since maximum temperatures are more affected than minima, a feature absent in non-coupled simulations. Regarding variability, the areas where the land-atmosphere coupling introduces larger changes are those where the reduction in the soil moisture content is more dramatic in future simulations, i.e., the so-called transitional zones. As regards precipitation, weaker positive signals for convective precipitation and more intense negative signals for non-convective precipitation are obtained as a result of the soil moisture-atmosphere interactions. These results highlight the crucial contribution of soil moisture to climate change projections and suggest its plausible key role for future projections of extreme events
Moduli Stabilization and Cosmology of Type IIB on SU(2)-Structure Orientifolds
We consider type IIB flux compactifications on six-dimensional
SU(2)-structure manifolds with O5- and O7-planes. These six-dimensional spaces
allow not only for F_3 and H_3 fluxes but also for F_1 and F_5 fluxes. We
derive the four-dimensional N=1 scalar potential for such compactifications and
present one explicit example of a fully stabilized AdS vacuum with large volume
and small string coupling. We then discuss cosmological aspects of these
compactifications and derive several no-go theorems that forbid dS vacua and
slow-roll inflation under certain conditions. We also study concrete examples
of cosets and twisted tori and find that our no-go theorems forbid dS vacua and
slow-roll inflation in all but one of them. For the latter we find a dS
critical point with \epsilon numerically zero. However, the point has two
tachyons and eta-parameter \eta \approx -3.1.Comment: 35 pages + appendices, LaTeX2e; v2: numerical dS extremum added,
typos corrected, references adde
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