259 research outputs found

    Analysis and evaluation of levels of awareness and understanding of fooball tactics by a game board

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    El siguiente estudio aborda la relación existente entre el plano de acción y el plano de representación de los sujetos, a través del papel que proporcionan los procesos de comprensión y toma de conciencia que suceden en el interior del individuo cuando se enfrenta a situaciones de juego que demanda un deporte no lineal, con características sumamente abiertas, como es el fútbol. El objetivo que pretendemos es analizar y evaluar la toma de conciencia y comprensión táctica del jugador infantil de fútbol base, desde la perspectiva funcional-estructural. Para ello, se ha utilizado un juego de tablero simulador de fútbol, diseñado a partir de la reglamentación básica que rige este deporte. La muestra utilizada está compuesta por ocho sujetos varones de categoría infantil, divididos en dos niveles de pericia: alto y bajo. Por tanto, se trata de un análisis centrado en el jugador (Garganta, 2001). Los ítems utilizados para realizar este análisis de la comprensión táctica de los jugadores se pueden categorizar siguiendo los principios tácticos de juego en fútbol que detalla Claude Bayer (1987). A su vez, los contenidos tácticos que se detallan en los ítems, se clasifican en aspectos tácticos de tipo individual -ofensivo y defensivo-, grupal -ofensivo y defensivo- y colectivo -ofensivo y defensivo-, siguiendo las clasificaciones propuestas por Fradua (1997), Garganta y Pinto (1997), Sánchez y Fradua (2001).The following study addresses the relationship between the level of action and the level of representation of the subject, through the paper that provide the processes of understanding and awareness that occur within the individual when confronted with game situations sport demands a nonlinear, with features very open, like football. The objective we intend to analyze and evaluate the awareness and tactical understanding of children's football player base, from the structural-functional perspective. For this, we used a board game football simulator, designed from the basic regulations governing the sport. The sample is composed of eight junior class male subjects, divided into two skill levels: high and low. Therefore, an analysis is centered on the player (throat, 2001). The items used for this analysis of tactical understanding of the players can be categorized according to the principles of tactical football game detailing Claude Bayer (1987). In turn, the contents listed in tactical items are classified in tactical aspects of individual type-offensive and defensive-, group-offensive and defensive-and collectiveoffensive and defensive-, following the classification proposed by Fradua (1997 ), Throat and Pinto (1997), Sanchez and Fradua (2001)

    Digestibilidad in vitro del dsRNA específico por enzimas del tracto digestivo del camarón Litopenaeus vannamei

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    Objective. The digestibility of specific dsRNA by action of the enzymes of digestive tract of the whiteleg shrimp Litopenaeus vannamei was determined in vitro. Materials and methods. Digestive enzyme activity (amylase, lipase, protease, DNase and RNase) was measured in the stomach, digestive gland, and anterior, middle, and posterior intestine of juvenile shrimp, and the digestibility of DNA, RNA and the dsRNA-ORF89, specific to WSSV, was determined by in vitro assays, as well as electrophoretic and densitometric analyses. Results. The highest enzymatic activity was found in the digestive gland: amylase (81.41%), lipase (92.60%), protease (78.20%), DNase (90.85%), and RNase (93.14%). The highest digestive capacity against DNA, RNA, and dsRNA was found in the digestive gland (5.11 ng of DNA per minute, 8.55 ng of RNA per minute, and 1.48 ng dsRNA per minute). Conclusions. The highest digestibility of dsRNA-ORF89, specific to WSSV, was found in the digestive gland, whereas the lowest digestibility was observed in the posterior intestine. This is the first report regarding the digestibility of dsRNA-ORF89 by whiteleg shrimp digestive tract enzymes, with potential therapeutic importance in shrimp culture to prevent WSSV disease through balanced feed.Objetivo. La digestibilidad del dsRNA específico para el virus de la mancha blanca (WSSV) por acción de las enzimas del tracto digestivo del camarón Litopenaeus vannamei fue analizada in vitro. Material y métodos. Se midió la actividad de enzimas digestivas (proteasa, amilasa, lipasa, ADNasa y ARNasa) en el estómago, la glándula digestiva, el intestino anterior, medio y posterior en juveniles de camarón patiblanco y se evaluó la digestibilidad de ácidos nucleicos ADN, ARN y dsRNA-ORF89 especifico contra el virus WSSV, por análisis electroforéticos y densitometría. Resultados. La actividad enzimática más alta se encontró en la glándula digestiva del camarón: amilasa (81.41%), lipasa (92.60%), proteasa (78.20%), ADNasa (90.85%) y ARNasa (93.14%). Se evidenció la capacidad digestiva del camarón patiblanco contra el ADN, ARN y dsRNA-ORF89 encontrando en la glándula digestiva la mayor digestión (5.11 ng de ADN por minuto, 8.55 ng de ARN por minuto y 1.48 ng de dsRNA por minuto). Conclusiones. La mayor digestibilidad del dsRNA-ORF89, específico contra el virus WSSV, se encontró en la glándula digestiva y la menor en el intestino posterior. Este es el primer informe relacionado con la digestibilidad del dsRNA-ORF89 por las enzimas del camarón patiblanco con potencial importancia terapéutica en el cultivo de camarón para prevenir la enfermedad del WSSV a través del alimento balanceado

    Análisis y evaluación de los niveles de toma de conciencia y comprensión táctica en fútbol por medio de un tablero de juego

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    The following study addresses the relationship between the level of action and the level of representation of the subject, through the paper that provide the processes of understanding and awareness that occur within the individual when confronted with game situations sport demands a nonlinear, with features very open, like football. The objective we intend to analyze and evaluate the awareness and tactical understanding of children's football player base, from the structural-functional perspective. For this, we used a board game football simulator, designed from the basic regulations governing the sport. The sample is composed of eight junior class male subjects, divided into two skill levels: high and low. Therefore, an analysis is centered on the player (throat, 2001). The items used for this analysis of tactical understanding of the players can be categorized according to the principles of tactical football game detailing Claude Bayer (1987). In turn, the contents listed in tactical items are classified in tactical aspects of individual type-offensive and defensive-, group-offensive and defensive-and collective-offensive and defensive-, following the classification proposed by Fradua (1997 ), Throat and Pinto (1997), Sanchez and Fradua (2001).El siguiente estudio aborda la relación existente entre el plano de acción y el plano de representación de los sujetos, a través del papel que proporcionan los procesos de comprensión y toma de conciencia que suceden en el interior del individuo cuando se enfrenta a situaciones de juego que demanda un deporte no lineal, con características sumamente abiertas, como es el fútbol. El objetivo que pretendemos es analizar y evaluar la toma de conciencia y comprensión táctica del jugador infantil de fútbol base, desde la perspectiva funcional-estructural. Para ello, se ha utilizado un juego de tablero simulador de fútbol, diseñado a partir de la reglamentación básica que rige este deporte. La muestra utilizada está compuesta por ocho sujetos varones de categoría infantil, divididos en dos niveles de pericia: alto y bajo. Por tanto, se trata de un análisis centrado en el jugador (Garganta, 2001). Los ítems utilizados para realizar este análisis de la comprensión táctica de los jugadores se pueden categorizar siguiendo los principios tácticos de juego en fútbol que detalla Claude Bayer (1987). A su vez, los contenidos tácticos que se detallan en los ítems, se clasifican en aspectos tácticos de tipo individual -ofensivo y defensivo-, grupal -ofensivo y defensivo- y colectivo -ofensivo y defensivo-, siguiendo las clasificaciones propuestas por Fradua (1997), Garganta y Pinto (1997), Sánchez y Fradua (2001)

    On-Surface Thermal Stability of a Graphenic Structure Incorporating a Tropone Moiety

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    On-surface synthesis, complementary to wet chemistry, has been demonstrated to be a valid approach for the synthesis of tailored graphenic nanostructures with atomic precision. Among the different existing strategies used to tune the optoelectronic and magnetic properties of these nanostructures, the introduction of non-hexagonal rings inducing out-of-plane distortions is a promising pathway that has been scarcely explored on surfaces. Here, we demonstrate that non-hexagonal rings, in the form of tropone (cycloheptatrienone) moieties, are thermally transformed into phenyl or cyclopentadienone moieties upon an unprecedented surface-mediated retro–Buchner-type reaction involving a decarbonylation or an intramolecular rearrangement of the CO unit, respectivel

    Femtosecond laser microstructuring of zirconia dental implants

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    This study evaluated the suitability of femtosecond laser for microtexturizing cylindrical zirconia dental implants surface. Sixty-six cylindrical zirconia implants were used and divided into three groups: Control group (with no laser modification), Group A (microgropored texture), and Group B (microgrooved texture). Scanning electron microscopy observation of microgeometries revealed minimal collateral damage of the original surface surrounding the treated areas. Optical interferometric profilometry showed that ultrafast laser ablation increased surface roughness (Ra, Rq, Rz, and Rt) significantly for both textured patterns from 1.2× to 6×-fold when compared with the control group (p Group B 8.4% ± 0.42% > Group A 1.6% ± 0.35%) and aluminum (Control 4.3% ± 0.9% > Group B 2.3% ± 0.3% > Group A 1.16% ± 0.2%) in the laser-treated surfaces (p Group A 1.94% > Group B 1.72%) as the surfaces were processed with ultrashort laser pulses. We concluded that femtosecond laser microstructuring offers an interesting alternative to conventional surface treatments of zirconia implants as a result of its precision and minimal damage of the surrounding areas

    Deletion of delta-like 1 homologue accelerates renal inflammation by modulating the Th17 immune response

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    Preclinical studies have demonstrated that activation of the NOTCH pathway plays a key role in the pathogenesis of kidney damage. There is currently no information on the role of the Delta-like homologue 1 (DLK1), a NOTCH inhibitor, in the regulation of renal damage. Here, we investigated the contribution of DLK1 to experimental renal damage and the underlying molecular mechanisms. Using a Dlk1-null mouse model in the experimental renal damage of unilateral ureteral obstruction, we found activation of NOTCH, as shown by increased nuclear translocation of the NOTCH1 intracellular domain, and upregulation of Dlk2/hey-1 expression compared to wild-type (WT) littermates. NOTCH1 over-activation in Dlk1-null injured kidneys was associated with a higher inflammatory response, characterized by infiltration of inflammatory cells, mainly CD4/IL17A + lymphocytes, and activation of the Th17 immune response. Furthermore, pharmacological NOTCH blockade inhibited the transcription factors controlling Th17 differentiation and gene expression of the Th17 effector cytokine IL-17A and other related-inflammatory factors, linked to a diminution of inflammation in the injured kidneys. We propose that the non-canonical NOTCH ligand DLK1 acts as a NOTCH antagonist in renal injury regulating the Th17-mediated inflammatory response.MINECO | Instituto de Salud Carlos III (ISCIII), Grant/Award Number: PI17/00119; Ministerio de Economia y Competitividad, Grant/Award Number: SAF2015-66107-R; Comunidad Autonoma de Madrid, Grant/Award Number: B2017/ BMD-3751; Fondo Nacional de Desarroll

    Governança da responsabilidade em saúde em uma cidade no centro do México

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    Gross mode, the promotion of self-care obeys the guidelines of international organizations that seek to reduce social spending in medical care, but with the emphasis on personal responsibility. The objective of the present work is to discuss this formula, establishing a model for the study of the phenomenon. A documentary work was done with a non - probabilistic selection of sources indexed to national repositories, considering publication, and the inclusion of concepts  "health  policy", "health care programs", "prevention strategies" and "self-care". There are lines of investigation concerning the extension of the model.En términos generales, la promoción del autocuidado obedece a las pautas de las organizaciones internacionales que buscan reducir el gasto social en atención médica, pero con énfasis en la responsabilidad personal. El objetivo del presente trabajo es discutir esta fórmula, estableciendo un modelo para el estudio del fenómeno. Se realizó un trabajo documental con una selección no probabilística de fuentes indexadas a repositorios nacionales, considerando la inclusión de conceptos: "salud política", "programas de atención médica","estrategias de prevención"y"autocuidado". Se sugieren líneas de investigación sobre la extensión del modelo.Modo bruto, a promoção do autocuidado obedece às diretrizes das organizações internacionais que buscam reduzir os gastos sociais na assistência médica, mas com ênfase na responsabilidade pessoal. O objetivo do presente trabalho é discutir essa fórmula, estabelecendo um modelo para o estudo do fenômeno. Um trabalho documental foi realizado com uma seleção não - probabilística de fontes indexadas a repositórios nacionais, considerando a publicação, ea inclusão de conceitos "política de saúde", "programas de atenção à saúde", "estratégias de prevenção" e "autocuidado". Existem linhas de investigação sobre a extensão do modelo
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