431 research outputs found
Committee Influence Over Controversial Policy: The Reproductive Policy Case
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/74678/1/j.1541-0072.1999.tb01964.x.pd
Committee autonomy in parliamentary systems â coalition logic or congressional rationales?
The Institutions of Politics; Design, Workings, and implications ( do not use, ended 1-1-2020
Election proximity and representation focus in party-constrained environments
Do elected representatives have a time-constant representation focus or do they adapt their focus depending on election proximity? In this article, we examine these overlooked theoretical and empirical puzzles by looking at how reelection-seeking actors adapt their legislative behavior according to the electoral cycle. In parliamentary democracies, representatives need to serve two competing principals: their party and their district. Our analysis hinges on how representatives make a strategic use of parliamentary written questions in a highly party-constrained institutional context to heighten their reselection and reelection prospects. Using an original data set of over 32,000 parliamentary questions tabled by Portuguese representatives from 2005 to 2015, we examine how time interacts with two key explanatory elements: electoral vulnerability and party size. Results show that representation focus is not static over time and, in addition, that electoral vulnerability and party size shape strategic use of parliamentary questions
High spatial and temporal resolution wide-field imaging of neuron activity using quantum NV-diamond
A quantitative understanding of the dynamics of biological neural networks is fundamental to gaining insight into information processing in the brain. While techniques exist to measure spatial or temporal properties of these networks, it remains a significant challenge to resolve the neural dynamics with subcellular spatial resolution. In this work we consider a fundamentally new form of wide-field imaging for neuronal networks based on the nanoscale magnetic field sensing properties of optically active spins in a diamond substrate. We analyse the sensitivity of the system to the magnetic field generated by an axon transmembrane potential and confirm these predictions experimentally using electronically-generated neuron signals. By numerical simulation of the time dependent transmembrane potential of a morphologically reconstructed hippocampal CA1 pyramidal neuron, we show that the imaging system is capable of imaging planar neuron activity non-invasively at millisecond temporal resolution and micron spatial resolution over wide-fields
Online Political Communication Strategies: MEPs, E-Representation, and Self-Representation
Research into the communication strategies of legislators has a long history. The European Parliament offers an opportunity to add to understanding of how legislators prioritize styles of communication, with a comparative perspective across 27 nations. Through content analysis of online communication, we investigate how the Internet is used by members of the European Parliament. Our analysis assesses three communication strategies: homestyle, impression management, and participatory. We find that a homestyle strategy predominates, followed by impression management. Participatory communication is emergent, but may earn legislators political capital, as it appears that proactive communicators who offer participatory opportunities are more likely to build an online following
The Consolidation of the White Southern Congressional Vote
This article explores the initial desertion and continued realignment of about one-sixth of the white voters in the South who, until 1994, stood by Democratic congressional candidates even as they voted for Republican presidential nominees. Prior to 1994, a sizable share of the white electorate distinguished between Democratic congressional and presidential candidates; since 1994 that distinction has been swept away. In 1992, a majority of white southern voters was casting their ballot for the Democratic House nominee; by 1994, the situation was reversed and 64 percent cast their ballot for the Republican. Virtually all categories of voters increased their support of Republican congressional candidates in 1994 and the following elections further cement GOP congressional support in the South. Subsequent elections are largely exercises in partisanship, as the congressional votes mirror party preferences. Republicans pull nearly all GOP identifiers, most independents, and a sizeable minority of Democratic identifiers. Democrats running for Congress no longer convince voters that they are different from their partyâs presidential standard bearersâa group that has consistently been judged unacceptable to overwhelming proportions of the southern white electorate.Yeshttps://us.sagepub.com/en-us/nam/manuscript-submission-guideline
Introduction: Connecting with the Electorate? Parliamentary Communication in EU Affairs
ational parliaments have often been described as latecomers to European integration, but there is little doubt that they have developed the institutional means to become more involved over the last few years â and especially since the Lisbon Treaty. Accordingly, the main focus of the literature has been on this institutional adaptation and thus on the relationship between the parliament and the government in European Union (EU) affairs. Other parliamentary functions, and in particular those that relate to their citizens such as the communication function, by contrast, have been largely neglected. Yet democracy depends on a viable public debate on policy choices and political alternatives to allow citizens to make informed political (electoral) choices and to exercise democratic control. This collection therefore investigates whether, and how, individual members of parliament, political parties, or legislatures as institutions âlinkâ with their electorates in EU politics. This introduction discusses why engaging with the public in EU affairs is â or at least should be â an important aspect of parliamentary work, introduces parliamentary means of communication and assesses parliamentary incentives and disincentives âto go publicâ in EU politics. (author's abstract
Treponema denticola chymotrypsin-like proteinase may contribute to orodigestive carcinogenesis through immunomodulation
Background: Periodontal pathogens have been linked to oral and gastrointestinal (orodigestive) carcinogenesis. However, the exact mechanisms remain unknown. Treponema denticola (Td) is associated with severe periodontitis, a chronic inflammatory disease leading to tooth loss. The anaerobic spirochete Td is an invasive bacteria due to its major virulence factor chymotrypsin-like proteinase. Here we aimed to investigate the presence of Td chymotrypsin-like proteinase (Td-CTLP) in major orodigestive tumours and to elucidate potential mechanisms for Td to contribute to carcinogenesis. Methods: The presence of Td-CTLP within orodigestive tumour tissues was examined using immunohistochemistry. Oral, tonsillar, and oesophageal squamous cell carcinomas, alongside gastric, pancreatic, and colon adenocarcinomas were stained with a Td-CTLP-specific antibody. Gingival tissue from periodontitis patients served as positive controls. SDS-PAGE and immunoblot were used to analyse the immumodulatory activity of Td-CTLP in vitro. Results: Td-CTLP was present in majority of orodigestive tumour samples. Td-CTLP was found to convert pro MMP-8 and -9 into their active forms. In addition, Td-CTLP was able to degrade the proteinase inhibitors TIMP-1, TIMP-2, and alpha-1-antichymotrypsin, as well as complement C1q. Conclusions: Because of its presence within tumours and regulatory activity on proteins critical for the regulation of tumour microenvironment and inflammation, the Td-CTLP may contribute to orodigestive carcinogenesis.Peer reviewe
Assessing the Effects of Personal Characteristics and Context on U.S. House Speakersâ Leadership Styles, 1789-2006
Research on congressional leadership has been dominated in recent decades by contextual interpretations that see leadersâ behavior as best explained by the environment in which they seek to exercise leadershipâparticularly, the preference homogeneity and size of their party caucus. The role of agency is thus discounted, and leadersâ personal characteristics and leadership styles are underplayed. Focusing specifically on the speakers of the U.S. House of Representatives from the first to the 110th Congress, we construct measures of each speakerâs commitment to comity and leadership assertiveness. We find the scores reliable and then test the extent to which a speakerâs style is the product of both political context and personal characteristics. Regression estimates on speakersâ personal assertiveness scores provide robust support for a context-plus-personal characteristics explanation, whereas estimates of their comity scores show that speakersâ personal backgrounds trump context
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