Thermodynamics of a three-flavor nonlocal Polyakov--Nambu--Jona-Lasinio model

The present work generalizes a nonlocal version of the Polyakov loop-extended Nambu and Jona-Lasinio (PNJL) model to the case of three active quark flavors, with inclusion of the axial U(1) anomaly. Gluon dynamics is incorporated through a gluonic background field, expressed in terms of the Polyakov loop. The thermodynamics of the nonlocal PNJL model accounts for both chiral and deconfinement transitions. Our results obtained in mean-field approximation are compared to lattice QCD results for $N_\text{f}=2+1$ quark flavors. Additional pionic and kaonic contributions to the pressure are calculated in random phase approximation. Finally, this nonlocal 3-flavor PNJL model is applied to the finite density region of the QCD phase diagram. It is confirmed that the existence and location of a critical point in this phase diagram depends sensitively on the strength of the axial U(1) breaking interaction.Comment: 31 pages, 15 figures, minor changes compared to v

Nonlocal quark model beyond mean field and QCD phase transition

A nonlocal chiral quark model is consistently extended beyond mean field using a strict 1/Nc expansion scheme. The parameters of the nonlocal model are refitted to the physical values of the pion mass and the weak pion decay constant. The size of the 1/Nc correction to the quark condensate is carefully studied in the nonlocal and the usual local Nambu-Jona-Lasinio models. It is found that even the sign of the corrections can be different. This can be attributed to the mesonic cut-off of the local model. It is also found that the 1/Nc corrections lead to a lowering of the temperature of the chiral phase transition in comparison with the mean-field result. On the other hand, near the phase transition the 1/Nc expansion breaks down and a non-perturbative scheme for the inclusion of mesonic correlations is needed in order to describe the phase transition point.Comment: 4 pages, 4 figures, talk at the 3rd Joint International Hadron Structure'09 Conference, Tatranska Strba (Slovak Republic), Aug. 30-Sept. 3, 200

Towards finite density QCD with Taylor expansions

Convergence properties of Taylor expansions of observables, which are also used in lattice QCD calculations at non-zero chemical potential, are analyzed in an effective N_f = 2+1 flavor Polyakov-quark-meson model. A recently developed algorithmic technique allows the calculation of higher-order Taylor expansion coefficients in functional approaches. This novel technique is for the first time applied to an effective N_f = 2+1 flavor Polyakov-quark-meson model and the findings are compared with the full model solution at finite densities. The results are used to discuss prospects for locating the QCD phase boundary and a possible critical endpoint in the phase diagram.Comment: 11 pages, 6 figures; minor clarifying changes, version to be published in Phys. Lett.

Spontaneous parity and charge-conjugation violations at real isospin and imaginary baryon chemical potentials

The phase structure of two-flavor QCD is investigated at real isospin and imaginary quark chemical potentials by using the Polyakov-loop extended Nambu--Jona-Lasinio model. In the region, parity symmetry is spontaneously broken by the pion superfluidity phase transition, whereas charge-conjugation symmetry is spontaneously violated by the Roberge-Weiss transition. The chiral (deconfinement) crossover at zero isospin and quark chemical potentials is a remnant of the parity (charge-conjugation) violation. The interplay between the parity and charge-conjugation violations are analyzed, and it is investigated how the interplay is related to the correlation between the chiral and deconfinement crossovers at zero isospin and quark chemical potentials.Comment: 12 pages, 18 figures. Typos were revised. Symbols /P and /C were added in Figures 8a and 8b. Colors of the figures were changed. Some sentences were added and revise

Thermodynamics of the PNJL model

QCD thermodynamics is investigated by means of the Polyakov-loop-extended Nambu Jona-Lasinio (PNJL) model, in which quarks couple simultaneously to the chiral condensate and to a background temporal gauge field representing Polyakov loop dynamics. The behaviour of the Polyakov loop as a function of temperature is obtained by minimizing the thermodynamic potential of the system. A Taylor series expansion of the pressure is performed. Pressure difference and quark number density are then evaluated up to sixth order in quark chemical potential, and compared to the corresponding lattice data. The validity of the Taylor expansion is discussed within our model, through a comparison between the full results and the truncated ones.Comment: 6 pages, 5 figures, Talk given at the Workshop for Young Scientists on the Physics of Ultrarelativistic Nucleus-Nucleus Collisions (Hot Quarks 2006), Villasimius, Italy, 15-20 May 200

The phase structure of the Polyakov--quark-meson model beyond mean field

The Polyakov-extended quark-meson model (PQM) is investigated beyond mean-field. This represents an important step towards a fully dynamical QCD computation. Both the quantum fluctuations to the matter sector and the back-reaction of the matter fluctuations to the QCD Yang-Mills sector are included. Results on the chiral and confinement-deconfinement crossover/phase transition lines and the location of a possible critical endpoint are presented. Moreover, thermodynamic quantities such as the pressure and the quark density are discussed.Comment: 12 pages, 11 figure

Oleate but not stearate induces the regulatory phenotype of myeloid suppressor cells

Tumor infiltrating myeloid cells play contradictory roles in the tumor development. Dendritic cells and classical activated macrophages support anti- tumor immune activity via antigen presentation and induction of pro- inflammatory immune responses. Myeloid suppressor cells (MSCs), for instance myeloid derived suppressor cells (MDSCs) or tumor associated macrophages play a critical role in tumor growth. Here, treatment with sodium oleate, an unsaturated fatty acid, induced a regulatory phenotype in the myeloid suppressor cell line MSC-2 and resulted in an increased suppression of activated T cells, paralleled by increased intracellular lipid droplets formation. Furthermore, sodium oleate potentiated nitric oxide (NO) production in MSC-2, thereby increasing their suppressive capacity. In primary polarized bone marrow cells, sodium oleate (C18:1) and linoleate (C18:2), but not stearate (C18:0) were identified as potent FFA to induce a regulatory phenotype. This effect was abrogated in MSC-2 as well as primary cells by specific inhibition of droplets formation while the inhibition of de novo FFA synthesis proved ineffective, suggesting a critical role for exogenous FFA in the functional induction of MSCs. Taken together our data introduce a new unsaturated fatty acid-dependent pathway shaping the functional phenotype of MSCs, facilitating the tumor escape from the immune system