Fog function virtualization: A flexible solution for IoT applications

The Internet of Things applications must carefully assess certain crucial factors such as the real-time and largely distributed nature of the “things”. Fog Computing provides an architecture to satisfy those requirements through nodes located from near the “things” till the edge. The problem comes with the integration of the Fog nodes into current infrastructures. This process requires the development of complex software solutions and prevents Fog growth. In this paper we propose three innovations to enhance Fog: (i) a new orchestration policy, (ii) the creation of constellations of nodes, and (iii) Fog Function Virtualization (FFV). All together will complement Fog to reach its true potential as a generic scalable platform, running multiple IoT applications simultaneously. Deploying a new service is reduced to the development of the application code, fact that brings the democratization of the Fog Computing paradigm through ease of deployment and cost reduction.The authors thanks Rodolfo Milito for his insightful comments and revisions. Damian Roca work was supported by a Doctoral Scholarship provided by Fundación La Caixa. Josue V. Quiroga work was supported by a Doctoral Scholarship provided by the Mexican National Council of Science and Technology (CONACyT). This work has been supported by the Spanish Government (Severo Ochoa grants SEV2015-0493) and by the Spanish Ministry of Science and Innovation (contracts TIN2015-65316-P).Peer ReviewedPostprint (author's final draft

Disaggregated Computing. An Evaluation of Current Trends for Datacentres

Next generation data centers will likely be based on the emerging paradigm of disaggregated function-blocks-as-a-unit departing from the current state of mainboard-as-a-unit. Multiple functional blocks or bricks such as compute, memory and peripheral will be spread through the entire system and interconnected together via one or multiple high speed networks. The amount of memory available will be very large distributed among multiple bricks. This new architecture brings various benefits that are desirable in today’s data centers such as fine-grained technology upgrade cycles, fine-grained resource allocation, and access to a larger amount of memory and accelerators. An analysis of the impact and benefits of memory disaggregation is presented in this paper. One of the biggest challenges when analyzing these architectures is that memory accesses should be modeled correctly in order to obtain accurate results. However, modeling every memory access would generate a high overhead that can make the simulation unfeasible for real data center applications. A model to represent and analyze memory disaggregation has been designed and a statistics-based queuing-based full system simulator was developed to rapidly and accurately analyze applications performance in disaggregated systems. With a mean error of 10%, simulation results pointed out that the network layers may introduce overheads that degrade applications’ performance up to 66%. Initial results also suggest that low memory access bandwidth may degrade up to 20% applications’ performance.This project has received funding from the European Unions Horizon 2020 research and innovation programme under grant agreement No 687632 (dReDBox project) and TIN2015-65316-P - Computacion de Altas Prestaciones VII.Peer ReviewedPostprint (published version

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

The original version of this article unfortunately contained a mistake

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Fog function virtualization: A flexible solution for IoT applications

The Internet of Things applications must carefully assess certain crucial factors such as the real-time and largely distributed nature of the “things”. Fog Computing provides an architecture to satisfy those requirements through nodes located from near the “things” till the edge. The problem comes with the integration of the Fog nodes into current infrastructures. This process requires the development of complex software solutions and prevents Fog growth. In this paper we propose three innovations to enhance Fog: (i) a new orchestration policy, (ii) the creation of constellations of nodes, and (iii) Fog Function Virtualization (FFV). All together will complement Fog to reach its true potential as a generic scalable platform, running multiple IoT applications simultaneously. Deploying a new service is reduced to the development of the application code, fact that brings the democratization of the Fog Computing paradigm through ease of deployment and cost reduction.The authors thanks Rodolfo Milito for his insightful comments and revisions. Damian Roca work was supported by a Doctoral Scholarship provided by Fundación La Caixa. Josue V. Quiroga work was supported by a Doctoral Scholarship provided by the Mexican National Council of Science and Technology (CONACyT). This work has been supported by the Spanish Government (Severo Ochoa grants SEV2015-0493) and by the Spanish Ministry of Science and Innovation (contracts TIN2015-65316-P).Peer Reviewe

Disaggregated Computing. An Evaluation of Current Trends for Datacentres

Next generation data centers will likely be based on the emerging paradigm of disaggregated function-blocks-as-a-unit departing from the current state of mainboard-as-a-unit. Multiple functional blocks or bricks such as compute, memory and peripheral will be spread through the entire system and interconnected together via one or multiple high speed networks. The amount of memory available will be very large distributed among multiple bricks. This new architecture brings various benefits that are desirable in today’s data centers such as fine-grained technology upgrade cycles, fine-grained resource allocation, and access to a larger amount of memory and accelerators. An analysis of the impact and benefits of memory disaggregation is presented in this paper. One of the biggest challenges when analyzing these architectures is that memory accesses should be modeled correctly in order to obtain accurate results. However, modeling every memory access would generate a high overhead that can make the simulation unfeasible for real data center applications. A model to represent and analyze memory disaggregation has been designed and a statistics-based queuing-based full system simulator was developed to rapidly and accurately analyze applications performance in disaggregated systems. With a mean error of 10%, simulation results pointed out that the network layers may introduce overheads that degrade applications’ performance up to 66%. Initial results also suggest that low memory access bandwidth may degrade up to 20% applications’ performance.This project has received funding from the European Unions Horizon 2020 research and innovation programme under grant agreement No 687632 (dReDBox project) and TIN2015-65316-P - Computacion de Altas Prestaciones VII.Peer Reviewe

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study (Intensive Care Medicine, (2021), 47, 2, (160-169), 10.1007/s00134-020-06234-9)

The original version of this article unfortunately contained a mistake. The members of the ESICM Trials Group Collaborators were not shown in the article but only in the ESM. The full list of collaborators is shown below. The original article has been corrected