Francesca Petrella (dir.), Aide à domicile et services à la personne : les associations dans la tourmente

Le monopole historique des associations dans la branche de l’aide à domicile n’est plus. La mise en concurrence des modes de prestation de service (prestataires, mandataires, emplois directs) et des opérateurs (associatifs, publics, privés) amène les associations, dans un contexte de rationalisation budgétaire, à s’adapter, se repositionner, se professionnaliser, seuls moyens de ne pas mettre la clé sous la porte… pour certaines d’entre elles du moins. Et pour un temps, puisqu’il est trop tôt..

Francesca Petrella (dir.), Aide à domicile et services à la personne : les associations dans la tourmente

Le monopole historique des associations dans la branche de l’aide à domicile n’est plus. La mise en concurrence des modes de prestation de service (prestataires, mandataires, emplois directs) et des opérateurs (associatifs, publics, privés) amène les associations, dans un contexte de rationalisation budgétaire, à s’adapter, se repositionner, se professionnaliser, seuls moyens de ne pas mettre la clé sous la porte… pour certaines d’entre elles du moins. Et pour un temps, puisqu’il est trop tôt..

Environmental Impacts of Large-Scale Grid-Connected Ground-Mounted PV Installations

Available on: http://www.ep.liu.se/ecp/057/vol11/007/ecp57vol11_007.pdfInternational audienceThis study characterizes the environmental performances of large-scale ground-mounted PV installations by considering a life-cycle approach. The methodology is based on the application of the existing international standards of Life Cycle Assessment (LCA). Four scenarios are compared, considering fixedmounting structures with (1) primary aluminum supports or (2) wood supports, and mobile structures with (3) single-axis trackers or (4) dual-axis trackers. Life cycle inventories are based on manufacturers' data combined with additional calculations and assumptions. Fixed-mounting installations with primary aluminum supports show the largest environmental impact potential with respect to human health, climate change and energy consumption. The climate change impact potential ranges between 37.5 and 53.5 gCO2eq/kWh depending on the scenario, assuming 1700 kWh/m².yr of irradiation on an inclined plane (30°), and multi-crystalline silicon modules with 14% of energy production performance. Mobile PV installations with dual-axis trackers show the largest impact potential on ecosystem quality, with more than a factor 2 of difference with other considered installations. Supports mass and composition, power density (in MWp/acre of land) and energy production performances appear as key design parameters with respect to large-scale ground mounted PV installations environmental performances, in addition to modules manufacturing process energy inputs

Environmental impacts of large-scale grid-connected ground-mounted PV installations

World Renewable Energy Congress - Sweden, 8-13 May, 2011, Linköping, SwedenInternational audienceThis study characterizes the environmental performances of large-scale ground-mounted PV installations by considering a life cycle approach. The methodology is based on the application of the existing international standards of Life Cycle Assessment (LCA). Four scenarios are compared, considering fixed-mounting structures with (1) primary aluminum supports or (2) wood supports, and mobile structures with (3) single-axis trackers or (4) dual-axis trackers. Life cycle inventories are based on manufacturers' data combined with additional calculations and assumptions. Fixed-mounting installations with primary aluminum supports show the largest environmental impact potential with respect to human health, climate change and energy consumption. The climate change impact potential ranges between 37.5 and 53.5 g CO2 eq/kWh depending on the scenario, assuming 1700 kWh/m2 yr of irradiation on an inclined plane (30°), and multi-crystalline silicon modules with 14% of energy production performance. Mobile PV installations with dual-axis trackers show the largest impact potential on ecosystem quality, with more than a factor 2 of difference with other considered installations. Supports mass and composition, power density (in MWp/acre of land) and energy production performances appear as key design parameters with respect to large-scale ground-mounted PV installations environmental performances, in addition to modules manufacturing process energy inputs

Environmental Impacts of Solar Thermal Systems with Life Cycle Assessment

Available on: http://www.ep.liu.se/ecp/057/vol14/002/ecp57vol14_002.pdfInternational audienceSolar thermal systems are an ecological way of providing domestic hot water. They are experiencing a rapid growth since the beginning of the last decade. This study characterizes the environmental performances of such installations with a life-cycle approach. The methodology is based on the application of the international standards of Life Cycle Assessment. Two types of systems are presented. Firstly a temperate-climate system, with solar thermal collectors and a backup energy as heat sources. Secondly, a tropical system, with thermosiphonic solar thermal system and no backup energy. For temperate-climate systems, two alternatives are presented: the first one with gas backup energy, and the second one with electric backup energy. These two scenarios are compared to two conventional scenarios providing the same service, but without solar thermal systems. Life cycle inventories are based on manufacturer data combined with additional calculations and assumptions. The fabrication of the components for temperate-climate systems has a minor influence on overall impacts. The environmental impacts are mostly explained by the additional energy consumed and therefore depend on the type of energy backup that is used. The study shows that the energy pay-back time of solar systems is lower than 2 years considering gas or electric energy when compared to 100% gas or electric systems

High prevalence of PRPH2 in autosomal dominant retinitis pigmentosa in France and characterization of biochemical and clinical features.

International audiencePURPOSE:To assess the prevalence of PRPH2 in autosomal dominant retinitis pigmentosa (adRP), to report six novel mutations, to characterize the biochemical features of a recurrent novel mutation and to study the clinical features of adRP patients.DESIGN:Retrospective clinical and molecular genetic study.METHODS:Clinical investigations included visual field testing, fundus examination, high-resolution spectral-domain optical coherence tomography (OCT), fundus autofluorescence imaging and electroretinogram (ERG) recording. PRPH2 was screened by Sanger sequencing in a cohort of 310 French families with adRP. Peripherin-2 protein was produced in yeast and analyzed by Western blot.RESULTS:We identified 15 mutations, including 6 novel and 9 previously reported changes in 32 families, accounting for a prevalence of 10.3% in this adRP population. We showed that a new recurrent p.Leu254Gln mutation leads to protein aggregation, suggesting abnormal folding. The clinical severity of the disease in examined patients was moderate with 78% of the eyes having 1 to 0.5 of visual acuity and 52% of the eyes retaining more than 50% of the visual field. Some patients characteristically showed vitelliform deposits or macular involvement. In some families, pericentral RP or macular dystrophy were found in family members while widespread RP was present in other members of the same families.CONCLUSIONS:The mutations in PRPH2 account for 10.3% of adRP in the French population, which is higher than previously reported (0-8%) This makes PRPH2 the second most frequent adRP gene after RHO in our series. PRPH2 mutations cause highly variable phenotypes and moderate forms of adRP, including mild cases which could be underdiagnosed

Low Vitamin D in Narcolepsy with Cataplexy

Narcolepsy with cataplexy (NC) is currently thought to be an autoimmune-mediated disorder in which environmental risk factors make a significant contribution to its development. It was proposed that vitamin D deficiency plays a role in autoimmune diseases. Here we investigated whether NC can be associated with 25-hydroxyvitamin D (25(OH)D) level deficiency in patients with NC compared with gender- and age-matched normal controls.Serum level of 25 (OH)D was determined in 51 European patients with typical NC compared to 55 age-, gender-, and ethnicity-matched healthy controls. Demographic and clinical data (age at onset, duration and severity of disease at baseline, and treatment intake at time of study) and season of blood sampling were collected to control for confounding variables.Serum 25(OH)D concentration was lower in NC compared to controls (median, 59.45 nmol/l [extreme values 24.05-124.03] vs. 74.73 nmol/l [26.88-167.48] p = 0.0039). Patients with NC had significantly greater vitamin D deficiency (<75 nmol/l) than controls (72.5% vs 50.9%, p = 0.0238). Division into quartiles of the whole sample revealed that the risk of being affected with NC increased with lower 25(OH)D level, with a 5.34 OR [1.65-17.27] for the lowest quartile (p = 0.0051). Further adjustment for BMI did not modify the strength of the association (OR: 3.63, 95% CI = 1.06-12.46, p = 0.0191). No between BMI and 25(OH)D interaction, and no correlation between 25(OH)D level and disease duration or severity or treatment intake were found in NC.We found a higher frequency of vitamin D deficiency in NC. Further studies are needed to assess the contribution of hypovitaminosis D to the risk of developing narcolepsy, and to focus on the utility of assessing vitamin D status to correct potential deficiency