Characterization of Function-E-Chainble Sets in Topological Space

In this paper we introduce the concept of function-E-chain between two sets in topological spaces through continuous function which is the extension of function-E-chain between two points of the space. Simple characterization of function-?-chainable sets in terms of function –E-chains between their points has been established. In case of metric space, the equivalence of E-chainability and function-E-chainability of sets is also established in this paper. Further some results of [1] have been generalized. Subject Classification: AMS (2000):54A9

Analysis of drug promotional literature and its abidance to WHO guidelines

Background: Drug promotional literature (DPL) is used by the pharmaceutical companies for promotion of their drug. It is the commonest source for providing information about the drug to the physician. According to WHO promotional literature should be reliable, truthful, informative, balanced and up to date.Methods: Study was conducted in Department of Pharmacology, Muzaffarnagar Medical College. 200 drug promotional literatures like advertisements published in medical journal, package insert of medicinal products and brochures were collected and analysed according to WHO criteria.Results: Total 200 promotional literatures were analysed. 100 promotional literatures were from the medical journal, 50 were package inserts of medicinal products and 50 were medicinal brochures. On assessing DPL using WHO criteria, all DPL mentioned brand names and dosage form (100%). Most of them published the generic name (98.5%), therapeutic uses (78%), side- effects (75%), dosage regimen (70%), contraindication (62.5%), warnings (55%), drug interaction (54%), precaution (50%), reference to scientific literature (45%), name of manufacture and distributor (99%), address of manufacturer and distributor (50%). Out of 200 DPL only 151 DPL contain references to scientific literature, 88 DPL references were retrievable and 63 were non retrievable.Conclusions: Our study shows although pharmaceutical companies are trying to adhere to the WHO criteria it is not fulfilled. As DPL are an important source of seeking information by the medical practitioner who rely on them to impart treatment to the patient, strict steps to regulate fulfilment of the WHO criteria should be taken by the government and authorities

Extraction and characterization of oil from seeds of the medicinal plant Withania coagulans (Stocks) Dunal (Doda paneer)

Withania coagulans (Stocks) Dunal commonly known as Doda panner/ Indian Rennet is a well-known medicinal plant but remains underutilized mainly due to scarce distribution in nature and extremely poor germination rate. In the present study oil was extracted from seeds of Withania coagulans which was subsequently subjected to FTIR and GC-MS analysis to identify phytochemical components of extracted oil. FTIR analysis revealed presence of diverse group of compounds including alcohols, alkane, alkene, aldehyde, ketone and halo compounds. GC-MS analysis depicted presence of 49 phytoconstituents in the oil extracted from seeds of W. coagulans. among which hexanoic acid, n-hexadecenoic acid, Vitamin E, gamma-Tocopherol, squalene, fucosterol, 2-Pyrrolidinone, 1-methyl, octadecanoic acid represent major phytoconstituents identified. Several compounds identified to be present in extracted oil have been reported to possess one or more pharmacological activity. Hence, the study suggests validation of plant oil to be utilized as ingredient of different pharmacological, cosmetic and other food products

A prospective study to compare the efficacy of tacrolimus vs cyclosporine in vernal keratoconjunctivitis in children in India

Background: Vernal keratoconjunctivitis (VKC) is a chronic allergic conjunctival disease. Immunomodulatory drugs like cyclosporine is being used for its treatment. Tacrolimus is another immunomodulator drug that can be used in VKC. This study was done to compare the efficacy of tacrolimus and cyclosporine in VKC.Methods: This prospective study was conducted on 60 patients of either sex by dividing them into two groups. The first group was treated with cyclosporine (0.05%) ophthalmic eye drop and second group with tacrolimus (0.03%) ophthalmic ointment. Total five objective signs (hyperaemia, oedema, papillae, corneal involvement and tantra’s dot) and five subjective symptoms (itching, tearing, foreign body sensation, discharge and photophobia) data was collected and tabulated for statistical analysis.Results: Authors found TSSS in both groups decrease significantly (p <0.05 or p <0.01 or p <0.001) at all post periods as compared to respective predecessor periods except 4 weeks to 6 weeks in cyclosporine group and 6 weeks to 8 weeks in tacrolimus group. Similarly, for each period, on comparing the mean TSSS between the groups TSSS between the groups at all periods does not differed statistically though at final evaluation (mean change from baseline to 8 weeks), it improved 5.2% more in tacrolimus group (83.7%) than cyclosporine group (78.5%). Similarly, TOSS also decreased at all post periods except 4 weeks to 6 weeks, and 6 weeks to 8 weeks in cyclosporine group and 6 weeks to 8 weeks in tacrolimus group. Improvement in scores was 11.6% more in tacrolimus (81.6%) than cyclosporine (70.0%). Cyclosporine eye drops are associated with burning sensation and redness of eyes while transient ocular irritation was only observed side effect with tacrolimus.Conclusions: The study found tacrolimus is clinically better drug for treatment of vernal keratoconjunctivitis than cyclosporine and is also cost effective

Effect of air pollutants on physiological parameters and yield attributes of paddy and wheat crops in Faridabad region, India

Air pollution is one of the major problems in the Delhi NCR region due to industrial emissions, traffic congestion, population growth and rapid development. Air pollutants deteriorate the environment, human health, plants and crops. This study focuses on the physiological parameters and yield attributes of paddy and wheat crops in the vicinity of a gas-based national thermal power plant (NTPC) located in Faridabad. Ten sites were selected, including the control site within a 10 km aerial distance from the exhaust chimney stack of the power plant. Major air pollutants, such as NOx, SOx, O3, and PM10, were monitored using Central Pollution Control Board (CPCB) guidelines. The air quality index (AQI) was moderately polluted at the sampling site, while good air quality was observed at the control site. The results showed that the photosynthetic rates were reduced to 46% in paddies and 48% in wheat crops. In the vegetative growth stage of paddies and wheat crops, the stomatal conductance of paddies decreased to 0.11 mmol m-2s-1 compared to 0.19 mmol m-2s-1 at the control site. The transpiration rate ranged from 0.6 to 7.7 μmol/m2/s in paddies and 1.2 to 9.8 μmol/m2/s in wheat crops. The R2 value ranged from 0.702 to 0.985, which shows a strong impact of the air quality index on the physiological parameters of crops. The yield reduction due to air pollution in paddies was 11.6%, and in wheat crops, it was 14.8%. This study also provides an inventory of air pollutants in Faridabad region and their subsequent impacts on crops

AIR POLLUTION TOLERANCE INDEX OF WHEAT AND RICE IN THE PROXIMITY OF GAS BASED POWER PLANT

The study aimed to identify the tolerance level of rice and wheat due to air pollutants around the gas-based power plant. Ten sites were selected around 10km radius of gas based power plant. Major air pollutants like NOx, SOx, ozone, and PM10 were monitored in ten sites during the growth of rice and wheat. The Air Quality Index (AQI) of villages falls mostly in the category of moderately polluted sites. Air Pollution Tolerance Index (APTI) is a tool applied for categorizing sensitive or tolerant plants towards air pollution and is calculated by using four biochemical parameters like total chlorophyll content, ascorbic acid, pH, and relative water content of rice and wheat. Results indicated that the pH of cell sap of both the crops was acidic to neutral pH (3.5-6.9) at polluted sites while neutral to slightly alkaline (7.0-7.9) at less polluted sites. Ascorbic acid content was high at polluted sites since ascorbic acid shows a defense mechanism against air pollution. Chlorophyll content (up to 0.61mg/g) and relative water content have shown a significant decrease at most polluted sites. As per APTI values (APTI&lt;11), both the crops were sensitive to air pollution in the selected area. APTI might be beneficial in the selection of crop species in the polluted area which shows that a higher concentration of air pollutants can damage crops severely. APTI was found to be positively correlated with pH, total chlorophyll content, and relative water content and negatively correlated with ascorbic acid

An automated algorithm for the quantification of hCG level in novel fabric-based home pregnancy test kits

We report a new image processing algorithm that extracts quantitative information about the concentration of human chorionic gonadotropin (hCG), an important early pregnancy marker, from commercially available qualitative home pregnancy kits. The algorithm could potentially be ported onto a simple camera based cell phone making it a low-cost, portable point-of-care device as opposed to costly and time consuming clinical labs for accurate quantitative determination of hCG. The algorithm takes the image of the test result as input, classifies and determines the hCG concentration based on the RGB intensities of the test line. The efficacy of the algorithm is demonstrated using control samples on commercially available strips as well as novel fabric based strips designed for this application

A study of menstrual hygiene practices and associated environmental & social factors among adolescent girls in rural Puducherry

Introduction. Adolescent females were prevented from receiving the appropriate knowledge due to social restrictions and traditional beliefs, which in turn led to poor hygiene habits. Material and methods. A community-based descriptive cross-sectional study employing a semi-structured questionnaire was carried out in the rural field practice region of MGMCRI, Puducherry, between the 15th of March 2019 and the 31st of April 2021. The study was done in Puducherry. The comprehensive enumeration yielded a total of 528 countable teenage females. Results. The vast majority of the teenage females (89.2%) reported using sanitary pads, whereas just 6.6% and 4.2%, respectively, reported using fresh or reused towels. 65.3% of the girls changed their wet absorbent between two and five times during the day. The vast majority of the girls, or 60.8% of them, disposed of their spent absorbent by either burying it or burning it. 67.9% of the girls were cleansing their genitalia when they were urinating. 54.4% of people cleaned their hands using soap and water, whereas 1.4% utilized ash soil, muddy dirt, or other types of soil. There was a statistically significant correlation between the style of housing and the availability of sanitary latrines (p<0.005) in relation to menstrual hygiene behaviors. Conclusions. This research also highlighted the absence of sanitary toilet facilities in the majority of residences, which negatively impacted the girls' ability to maintain their privacy and led to bad practices around menstruation hygiene

Structured Collaboration Across a Transformative Knowledge Network-Learning Across Disciplines, Cultures and Contexts?

Realising the Sustainable Development Goals (SDGs) will require transformative changes at micro, meso and macro levels and across diverse geographies. Collaborative, transdisciplinary research has a role to play in documenting, understanding and contributing to such transformations. Previous work has investigated the role of this research in Europe and North America, however the dynamics of transdisciplinary research on ‘transformations to sustainability’ in other parts of the world are less well-understood. This paper reports on an international project that involved transdisciplinary research in six different hubs across the globe and was strategically designed to enable mutual learning and exchange. It draws on surveys, reports and research outputs to analyse the processes of transdisciplinary collaboration for sustainability that took place between 2015-2019. The paper illustrates how the project was structured in order to enable learning across disciplines, cultures and contexts, and describes how it also provided for the negotiation of epistemological frameworks and different normative commitments between members across the network. To this end, it discusses lessons regarding the use of theoretical and methodological anchors, multi-loop learning and evaluating emergent change (including the difficulties encountered). It offers insights for the design and implementation of future international transdisciplinary collaborations that address locally-specific sustainability challenges within the universal framework of the 2030 Agenda for Sustainable Development

Proceedings of the 2nd International Workshop on Digital Language Archives: LangArc 2023

Article presenting an overview of the Bharatavani project, which focuses on recording socio-cultural and linguistic information about 121 Indian languages and making it accessible to a broader audience. It was presented at the 2nd International Workshop on Digital Language Archives held on June 30, 2023 as part of the ACM/IEEE Joint Conference on Digital Libraries 2023