147 research outputs found

    Downscaled Rainfall Prediction Model (DRPM) using a Unit Disaggregation Curve (UDC)

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    International audienceThis study was undertaken to identify the process for generating finer time scaled rainfall from higher time scaled data. The Downscaled Rainfall Prediction Model (DRPM) using the technique of unit disaggregation curve (UDC) was developed under the concept of coupling the stochastic autoregressive (AR) model with a wavelet filter and disaggregation model. Sequences of the number of rainy days and monthly rainfall were simulated from 52-year rainfall records at 4 stations in the northeastern part of Thailand. Compared with actual rainfall sequences, the 30 year generated sequences provided R-square values of 0.47-0.60. The model was applied to forecast the number of rainy days and monthly rainfall for the year of 2002. When compared with actual records the prediction model provided R-square values of 0.50 to 0.79

    Civilian-military malaria outbreak response in Thailand: an example of multi-stakeholder engagement for malaria elimination

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    Background In April 2017, the Thai Ministry of Public Health (MoPH) was alerted to a potential malaria outbreak among civilians and military personnel in Sisaket Province, a highly forested area bordering Cambodia. The objective of this study was to present findings from the joint civilian-military outbreak response. Methods A mixed-methods approach was used to assess risk factors among cases reported during the 2017 Sisaket malaria outbreak. Routine malaria surveillance data from January 2013 to March 2018 obtained from public and military medical reporting systems and key informant interviews (KIIs) (n = 72) were used to develop hypotheses about potential factors contributing to the outbreak. Joint civilian-military response activities included entomological surveys, mass screen and treat (MSAT) and vector control campaigns, and scale-up of the “1–3–7” reactive case detection approach among civilians alongside a pilot “1–3–7” study conducted by the Royal Thai Army (RTA). Results Between May–July 2017, the monthly number of MoPH-reported cases surpassed the epidemic threshold. Outbreak cases detected through the MoPH mainly consisted of Thai males (87%), working as rubber tappers (62%) or military/border police (15%), and Plasmodium vivax infections (73%). Compared to cases from the previous year (May–July 2016), outbreak cases were more likely to be rubber tappers (OR = 14.89 [95% CI: 5.79–38.29]; p \u3c 0.001) and infected with P. vivax (OR=2.32 [1.27–4.22]; p = 0.006). Themes from KIIs were congruent with findings from routine surveillance data. Though limited risk factor information was available from military cases, findings from RTA’s “1–3–7” study indicated transmission was likely occurring outside military bases. Data from entomological surveys and MSAT campaigns support this hypothesis, as vectors were mostly exophagic and parasite prevalence from MSAT campaigns was very low (range: 0-0.7% by PCR/microscopy). Conclusions In 2017, an outbreak of mainly P. vivax occurred in Sisaket Province, affecting mainly military and rubber tappers. Vector control use was limited to the home/military barracks, indicating that additional interventions were needed during high-risk forest travel periods. Importantly, this outbreak catalyzed joint civilian-military collaborations and integration of the RTA into the national malaria elimination strategy (NMES). The Sisaket outbreak response serves as an example of how civilian and military public health systems can collaborate to advance national malaria elimination goals in Southeast Asia and beyond

    Civilian-military malaria outbreak response in Thailand: an example of multi-stakeholder engagement for malaria elimination.

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    BACKGROUND: In April 2017, the Thai Ministry of Public Health (MoPH) was alerted to a potential malaria outbreak among civilians and military personnel in Sisaket Province, a highly forested area bordering Cambodia. The objective of this study was to present findings from the joint civilian-military outbreak response. METHODS: A mixed-methods approach was used to assess risk factors among cases reported during the 2017 Sisaket malaria outbreak. Routine malaria surveillance data from January 2013 to March 2018 obtained from public and military medical reporting systems and key informant interviews (KIIs) (n = 72) were used to develop hypotheses about potential factors contributing to the outbreak. Joint civilian-military response activities included entomological surveys, mass screen and treat (MSAT) and vector control campaigns, and scale-up of the "1-3-7" reactive case detection approach among civilians alongside a pilot "1-3-7" study conducted by the Royal Thai Army (RTA). RESULTS: Between May-July 2017, the monthly number of MoPH-reported cases surpassed the epidemic threshold. Outbreak cases detected through the MoPH mainly consisted of Thai males (87%), working as rubber tappers (62%) or military/border police (15%), and Plasmodium vivax infections (73%). Compared to cases from the previous year (May-July 2016), outbreak cases were more likely to be rubber tappers (OR = 14.89 [95% CI: 5.79-38.29]; p < 0.001) and infected with P. vivax (OR=2.32 [1.27-4.22]; p = 0.006). Themes from KIIs were congruent with findings from routine surveillance data. Though limited risk factor information was available from military cases, findings from RTA's "1-3-7" study indicated transmission was likely occurring outside military bases. Data from entomological surveys and MSAT campaigns support this hypothesis, as vectors were mostly exophagic and parasite prevalence from MSAT campaigns was very low (range: 0-0.7% by PCR/microscopy). CONCLUSIONS: In 2017, an outbreak of mainly P. vivax occurred in Sisaket Province, affecting mainly military and rubber tappers. Vector control use was limited to the home/military barracks, indicating that additional interventions were needed during high-risk forest travel periods. Importantly, this outbreak catalyzed joint civilian-military collaborations and integration of the RTA into the national malaria elimination strategy (NMES). The Sisaket outbreak response serves as an example of how civilian and military public health systems can collaborate to advance national malaria elimination goals in Southeast Asia and beyond

    Role of KRAS mutation in advanced ovarian cancers treated by targeted medicines in Thailand.

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    POPULATION SIZES OF BRYDE'S WHALE (BALAENOPTERA EDENI) IN THE UPPER GULF OF THAILAND, ESTIMATED BY MARK AND RECAPTURE METHOD

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    March 18-19, 2014The population size of Bryde's whale (Balaenoptera edeni) in the Upper Gulf of Thailand was estimated using mark and recapture method, during the period of January 2010 to December 2013. Forty-five whales were observed by identifying distinctive markings. Using the M(bh)-Pollock and Otto model in the Program CAPTURE and CJS model in the Program MARK, Bryde's whale population size and survival rate probability estimations were 63±8.48 (S.E.) animals and 0.88±0.04 (S.E.) respectively. Although the size of Bryde's whales population in the Upper Gulf was small, the likely trend is towards population increasing. Program MARK and CAPTURE have been utilized as tools for summarizing the status of animals after long-term monitoring

    The significance of KRAS mutations in advanced ovarian cancers treated by multitargeted therapy in Thailand.

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