425 research outputs found

    Using C to build a satellite scheduling expert system: Examples from the Explorer Platform planning system

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    A C-based artificial intelligence (AI) development effort which is based on a software tools approach is discussed with emphasis on reusability and maintainability of code. The discussion starts with simple examples of how list processing can easily be implemented in C and then proceeds to the implementations of frames and objects which use dynamic memory allocation. The implementation of procedures which use depth first search, constraint propagation, context switching, and blackboard-like simulation environment are described. Techniques for managing the complexity of C-based AI software are noted, especially the object-oriented techniques of data encapsulation and incremental development. Finally, all these concepts are put together by describing the components of planning software called the Planning And Resource Reasoning (PARR) Shell. This shell was successfully utilized for scheduling services of the Tracking and Data Relay Satellite System for the Earth Radiation Budget Satellite since May of 1987 and will be used for operations scheduling of the Explorer Platform in Nov. of 1991

    Using C to build a satellite scheduling expert system: Examples from the Explorer platform planning system

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    Recently, many expert systems were developed in a LISP environment and then ported to the real world C environment before the final system is delivered. This situation may require that the entire system be completely rewritten in C and may actually result in a system which is put together as quickly as possible with little regard for maintainability and further evolution. With the introduction of high performance UNIX and X-windows based workstations, a great deal of the advantages of developing a first system in the LISP environment have become questionable. A C-based AI development effort is described which is based on a software tools approach with emphasis on reusability and maintainability of code. The discussion starts with simple examples of how list processing can easily be implemented in C and then proceeds to the implementations of frames and objects which use dynamic memory allocation. The implementation of procedures which use depth first search, constraint propagation, context switching and a blackboard-like simulation environment are described. Techniques for managing the complexity of C-based AI software are noted, especially the object-oriented techniques of data encapsulation and incremental development. Finally, all these concepts are put together by describing the components of planning software called the Planning And Resource Reasoning (PARR) shell. This shell was successfully utilized for scheduling services of the Tracking and Data Relay Satellite System for the Earth Radiation Budget Satellite since May 1987 and will be used for operations scheduling of the Explorer Platform in November 1991

    War Hawks and Peace Doves: alternate resolutions of experimental conflicts

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68160/2/10.1177_002200276500900406.pd

    Post-operative monitoring of intestinal tissue oxygenation using an implantable microfabricated oxygen sensor

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    Anastomotic leakage (AL) is a common and dangerous post-operative complication following intestinal resection, causing substantial morbidity and mortality. Ischaemia in the tissue surrounding the anastomosis is a major risk-factor for AL development. Continuous tissue oxygenation monitoring during the post-operative recovery period would provide early and accurate early identification of AL risk. We describe the construction and testing of a miniature implantable electrochemical oxygen sensor that addresses this need. It consisted of an array of platinum microelectrodes, microfabricated on a silicon substrate, with a poly(2-hydroxyethyl methacrylate) hydrogel membrane to protect the sensor surface. The sensor was encapsulated in a biocompatible package with a wired connection to external instrumentation. It gave a sensitive and highly linear response to variations in oxygen partial pressure in vitro, although over time its sensitivity was partially decreased by protein biofouling. Using a pre-clinical in vivo pig model, acute intestinal ischaemia was robustly and accurately detected by the sensor. Graded changes in tissue oxygenation were also measurable, with relative differences detected more accurately than absolute differences. Finally, we demonstrated its suitability for continuous monitoring of tissue oxygenation at a colorectal anastomosis over a period of at least 45 h. This study provides evidence to support the development and use of implantable electrochemical oxygen sensors for post-operative monitoring of anastomosis oxygenation

    A Survey for Circumstellar Disks Around Young Substellar Objects

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    (Abridged) We have completed the first systematic survey for disks around spectroscopically identified young brown dwarfs and very low mass stars. We have obtained L'-band (3.8 um) imaging for 38 very cool objects in IC 348 and Taurus. Our targets span spectral types from M6 to M9.5 (~100 to ~15 Mjup). Using the objects' measured spectral types and extinctions, we find that most of our sample (77%+/-15%) possess intrinsic IR excesses, indicative of disks. Because the excesses are modest, conventional analyses using only IR colors would have missed most of the sources with excesses. The observed IR excesses are correlated with Halpha emission, consistent with a common accretion disk origin. The excesses can be explained by disk reprocessing of starlight alone; the implied accretion rates are at least an order of magnitude below typical values for classical T Tauri stars. The observed distribution of IR excesses suggests the presence of inner disk holes. The disk frequency appears to be independent of the mass and age. In the same star-forming regions, disks around brown dwarfs are at least as long-lived (~3 Myr) as disks around the T Tauri stars. Altogether, the frequency and properties of young circumstellar disks appear to be similar from the stellar regime down to the substellar and planetary-mass regime. This provides prima facie evidence of a common origin for most stars and brown dwarfs.Comment: ApJ, in press, 28 pages. Minor change to the online, abridged version of the abstract. No change to the actual pape

    Physiological concentrations of bile acids down-regulate agonist induced secretion in colonic epithelial cells

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    In patients with bile acid malabsorption, high concentrations of bile acids enter the colon and stimulate Cl− and fluid secretion, thereby causing diarrhoea. However, deoxycholic acid (DCA), the predominant colonic bile acid, is normally present at lower concentrations where its role in regulating transport is unclear. Thus, the current study set out to investigate the effects of physiologically relevant DCA concentrations on colonic epithelial secretory function. Cl− secretion was measured as changes in short-circuit current across voltage-clamped T84 cell monolayers. At high concentrations (0.5–1 mM), DCA acutely stimulated Cl− secretion but this effect was associated with cell injury, as evidenced by decreased transepithelial resistance (TER) and increased lactate dehydrogenase (LDH) release. In contrast, chronic (24 hrs) exposure to lower DCA concentrations (10–200 ÎŒM) inhibited responses to Ca2+ and cAMP-dependent secretagogues without altering TER, LDH release, or secretagogue-induced increases in intracellular second messengers. Other bile acids – taurodeoxycholic acid, chenodeoxycholic acid and cholic acid – had similar antisecretory effects. DCA (50 ÎŒM) rapidly stimulated phosphorylation of the epidermal growth factor receptor (EGFr) and both ERK and p38 MAPKs (mitogen-activated protein kinases). The EGFr inhibitor, AG1478, and the protein synthesis inhibitor, cycloheximide, reversed the antisecretory effects of DCA, while the MAPK inhibitors, PD98059 and SB203580, did not. In summary, our studies suggest that, in contrast to its acute prosecretory effects at pathophysiological concentrations, lower, physiologically relevant, levels of DCA chronically down-regulate colonic epithelial secretory function. On the basis of these data, we propose a novel role for bile acids as physiological regulators of colonic secretory capacity

    Exploring participatory visions of smart transport in Milton Keynes

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    This paper explores citizen concerns emerging in the design stage of MotionMap, a smart transport initiative developed in the context of a £16 million smart city programme. A city-wide sensing system integrated with other databases will provide real-time information about vehicular and pedestrian movement. The experience of a series of smart transport workshops in Milton Keynes suggests that citizens feel that they bear the cost of smart cities through potentially intrusive surveillance producing sacrifices in convenience and privacy, while the gains are captured by industrial and governmental actors. This distrust of surveillance through urban sensing systems is not inflexible. Such systems can gain legitimacy through a participatory approach where users legitimize the sensing system by taking an active role in providing transport data, as opposed to having it ‘harvested’ from them through passive or opportunistic mechanisms. Participatory approaches are challenging because users will engage only if the system can provide compelling benefits. A key contribution of this research comes from identifying that the benefits important to citizens are not necessarily measured in economic terms nor in terms of increased efficiency

    Roadmaps to Utopia: Tales of the Smart City

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    Notions of the Smart City are pervasive in urban development discourses. Various frameworks for the development of smart cities, often conceptualized as roadmaps, make a number of implicit claims about how smart city projects proceed but the legitimacy of those claims is unclear. This paper begins to address this gap in knowledge. We explore the development of a smart transport application, MotionMap, in the context of a ÂŁ16M smart city programme taking place in Milton Keynes, UK. We examine how the idealized smart city narrative was locally inflected, and discuss the differences between the narrative and the processes and outcomes observed in Milton Keynes. The research shows that the vision of data-driven efficiency outlined in the roadmaps is not universally compelling, and that different approaches to the sensing and optimization of urban flows have potential for empowering or disempowering different actors. Roadmaps tend to emphasize the importance of delivering quick practical results. However, the benefits observed in Milton Keynes did not come from quick technical fixes but from a smart city narrative that reinforced existing city branding, mobilizing a growing network of actors towards the development of a smart region. Further research is needed to investigate this and other smart city developments, the significance of different smart city narratives, and how power relationships are reinforced and constructed through them

    Understanding the Role of Designed Solid Acid Sites in the Low-Temperature Production of Ï”-Caprolactam

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    Modern society is placing increasing demands on commodity chemicals, driven by the ever‐growing global population and the desire for improved standards of living. As the polymer industry grows, a sustainable route to ϔ‐caprolactam, the precursor to the recyclable nylon‐6 polymer, is becoming increasingly important. To this end, we have designed and characterized a recyclable SAPO catalyst using a range of characterization techniques, to achieve near quantitative yields of ϔ‐caprolactam from cyclohexanone oxime. The catalytic process operates under significantly less energetically demanding conditions than other widely practiced industrial processes
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