1,074 research outputs found

    Experimental investigation of the impact of elastic turbulence on heat transfer in a serpentine channel

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    AbstractThe characteristics of convective heat transfer and fluid flow within a square cross-section serpentine channel are experimentally studied for two groups of polymeric viscoelastic fluids, shear-thinning and constant-viscosity Boger solutions. The elastic turbulence can be created by the non-linear interaction between elastic stresses generated within the flowing high-molecular-weight polymer solutions and the streamline curvature. In order to confirm elastic turbulence in this geometry, pressure drop across the serpentine channel was measured. The findings indicate that the measurements of non-dimensional pressure-drop increase approximately from 1.48 to 4.82 for viscoelastic solutions compared with the Newtonian fluid over a range of Weissenberg number from 4 to 211. The convective heat transfer enhances due to elastic turbulence by up to 200% for low polymer concentration (dilute) solutions and reaches up to 380% for higher polymer concentration (semi-dilute) solutions under creeping-flow conditions in comparison to that achieved by the equivalent Newtonian fluid flow at low Graetz number (up to 14.6). We propose a modified Weissenberg number which is able to approximately collapse the mean Nusselt number data for each solution group

    Anomalous material-dependent transport of focused, laser-driven proton beams.

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    Intense lasers can accelerate protons in sufficient numbers and energy that the resulting beam can heat materials to exotic warm (10 s of eV temperature) states. Here we show with experimental data that a laser-driven proton beam focused onto a target heated it in a localized spot with size strongly dependent upon material and as small as 35 μm radius. Simulations indicate that cold stopping power values cannot model the intense proton beam transport in solid targets well enough to match the large differences observed. In the experiment a 74 J, 670 fs laser drove a focusing proton beam that transported through different thicknesses of solid Mylar, Al, Cu or Au, eventually heating a rear, thin, Au witness layer. The XUV emission seen from the rear of the Au indicated a clear dependence of proton beam transport upon atomic number, Z, of the transport layer: a larger and brighter emission spot was measured after proton transport through the lower Z foils even with equal mass density for supposed equivalent proton stopping range. Beam transport dynamics pertaining to the observed heated spot were investigated numerically with a particle-in-cell (PIC) code. In simulations protons moving through an Al transport layer result in higher Au temperature responsible for higher Au radiant emittance compared to a Cu transport case. The inferred finding that proton stopping varies with temperature in different materials, considerably changing the beam heating profile, can guide applications seeking to controllably heat targets with intense proton beams

    A hybrid radiation detector for simultaneous spatial and temporal dosimetry

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    In this feasibility study an organic plastic scintillator is calibrated against ionisation chamber measurements and then embedded in a polymer gel dosimeter to obtain a quasi-4D experimental measurement of a radiation field. This hybrid dosimeter was irradiated with a linear accelerator, with temporal measurements of the dose rate being acquired by the scintillator and spatial measurements acquired with the gel dosimeter. The detectors employed in this work are radiologically equivalent; and we show that neither detector perturbs the intensity of the radiation field of the other. By employing these detectors in concert, spatial and temporal variations in the radiation intensity can now be detected and gel dosimeters can be calibrated for absolute dose from a single irradiation

    Solution structure of a repeated unit of the ABA-1 nematode polyprotein allergen of ascaris reveals a novel fold and two discrete lipid-binding sites

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    Parasitic nematode worms cause serious health problems in humans and other animals. They can induce allergic-type immune responses, which can be harmful but may at the same time protect against the infections. Allergens are proteins that trigger allergic reactions and these parasites produce a type that is confined to nematodes, the nematode polyprotein allergens (NPAs). These are synthesized as large precursor proteins comprising repeating units of similar amino acid sequence that are subsequently cleaved into multiple copies of the allergen protein. NPAs bind small lipids such as fatty acids and retinol (Vitamin A) and probably transport these sensitive and insoluble compounds between the tissues of the worms. Nematodes cannot synthesize these lipids, so NPAs may also be crucial for extracting nutrients from their hosts. They may also be involved in altering immune responses by controlling the lipids by which the immune and inflammatory cells communicate. We describe the molecular structure of one unit of an NPA, the well-known ABA-1 allergen of Ascaris and find its structure to be of a type not previously found for lipid-binding proteins, and we describe the unusual sites where lipids bind within this structur
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