82 research outputs found

    Trabalho, sofrimento e influência da sociedade de consumo em instituições públicas

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    Este trabalho trata de investigação acerca de sofrimento psíquico nos servidores de instituições públicas brasileiras em artigos publicados na plataforma Scielo no período 2004-2013, com o objetivo de analisar de que forma os diagnósticos teóricos publicados apontam os discursos e valores hegemônicos difundidos pelos meios de comunicação de massa e pela sociedade de consumo. A metodologia utilizada tratou-se de pesquisa qualitativa e análise de conteúdo dos dados. Foram analisados vinte e quatro artigos, selecionados os conceitos mais utilizados, os sujeitos de pesquisa e identificadas lacunas acerca das pesquisas em sofrimento no trabalho das instituições públicas no Brasil. Identificou-se que os principais conceitos apresentados acerca de sofrimentos psíquicos são burnout, transtornos psíquicos e condições precárias de trabalho. A matriz explicativa para a causa de sofrimento é composta, principalmente, por cansaço físico, vocal e/ou mental, sobrecarga de trabalho, burocratização da organização do trabalho, contaminação do tempo fora do trabalho e falta de reconhecimento. Conclui-se que é possível afirmar que o sofrimento dos servidores públicos pode ser ampliado por uma sociedade que através dos meios de comunicação de massa estabelece padrões

    Social contacts and loneliness affect the own age bias for emotional faces

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    Individuals are better at recognizing faces of their own age group (Own Age Bias) but it is unclear whether this bias occurs also for emotional faces and to what extent is affected by loneliness. Young individuals (N = 235) completed an age categorization task on faces of young and old individuals showing neutral, happy, and angry expressions. After a filler task, they categorized as seen or novel the original set of faces intermixed with a new set. Findings showed an Own Age Bias for novel young faces but no evidence that emotion eliminates it. Recognition accuracy was better for emotional faces, but the two factors did not interact. Importantly, low loneliness was linked to an Own Age Bias for novel happy faces. These findings are discussed in the context of current theoretical accounts of the Own Age Bias and of the effects of loneliness on attention and memory

    Cyclodimerization of stilbenes and styrenes catalyzed by heteropolyacid supported on silica

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    Several stilbenes and styrenes have been treated with heteropolyacid] (HPA) supported over silice. The compounds obtained were characterized by 1H and 13C-NMR and the yields were compared with those obtained using H2SO4 (c) and ethyl poliphosphate (PPE).Facultad de Ciencias Exacta

    PYL1- and PYL8-like ABA Receptors of Nicotiana benthamiana Play a Key Role in ABA Response in Seed and Vegetative Tissue

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    19 pags., 7 figs., 3 tabs. -- This article belongs to the Special Issue Drought and Heat Stress Signalling Responses in PlantsTo face the challenges of climate change and sustainable food production, it is essential to develop crop genome editing techniques to pinpoint key genes involved in abiotic stress signaling. The identification of those prevailing abscisic acid (ABA) receptors that mediate plant-environment interactions is quite challenging in polyploid plants because of the high number of genes in the PYR/PYL/RCAR ABA receptor family. Nicotiana benthamiana is a biotechnological crop amenable to genome editing, and given the importance of ABA signaling in coping with drought stress, we initiated the analysis of its 23-member family of ABA receptors through multiplex CRISPR/Cas9-mediated editing. We generated several high-order mutants impaired in NbPYL1-like and NbPYL8-like receptors, which showed certain insensitivity to ABA for inhibition of seedling establishment, growth, and development of shoot and lateral roots as well as reduced sensitivity to the PYL1-agonist cyanabactin (CB). However, in these high-order mutants, regulation of transpiration was not affected and was responsive to ABA treatment. This reveals a robust and redundant control of transpiration in this allotetraploid plant that probably reflects its origin from the extreme habitat of central Australia.This research was supported by grant PID2020-113100RB (P.L.R.) and PID2020-119805RB (A.A.) funded by MCIN/AEI/10.13039/501100011033 and by Newcotiana H2020 760331 (D.O.).Peer reviewe

    Experimental ‘Jet Lag’ Inhibits Adult Neurogenesis and Produces Long-Term Cognitive Deficits in Female Hamsters

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    Background: Circadian disruptions through frequent transmeridian travel, rotating shift work, and poor sleep hygiene are associated with an array of physical and mental health maladies, including marked deficits in human cognitive function. Despite anecdotal and correlational reports suggesting a negative impact of circadian disruptions on brain function, this possibility has not been experimentally examined. Methodology/Principal Findings: In the present study, we investigated whether experimental ‘jet lag ’ (i.e., phase advances of the light:dark cycle) negatively impacts learning and memory and whether any deficits observed are associated with reductions in hippocampal cell proliferation and neurogenesis. Because insults to circadian timing alter circulating glucocorticoid and sex steroid concentrations, both of which influence neurogenesis and learning/memory, we assessed the contribution of these endocrine factors to any observed alterations. Circadian disruption resulted in pronounced deficits in learning and memory paralleled by marked reductions in hippocampal cell proliferation and neurogenesis. Significantly, deficits in hippocampal-dependent learning and memory were not only seen during the period of the circadian disruption, but also persisted well after the cessation of jet lag, suggesting long-lasting negative consequences on brain function. Conclusions/Significance: Together, these findings support the view that circadian disruptions suppress hippocampal neurogenesis via a glucocorticoid-independent mechanism, imposing pronounced and persistent impairments on learnin

    Effects of circadian disruption on physiology and pathology: from bench to clinic (and back)

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    Nested within the hypothalamus, the suprachiasmatic nuclei (SCN) represent a central biological clock that regulates daily and circadian (i.e., close to 24 h) rhythms in mammals. Besides the SCN, a number of peripheral oscillators throughout the body control local rhythms and are usually kept in pace by the central clock. In order to represent an adaptive value, circadian rhythms must be entrained by environmental signals or zeitgebers, the main one being the daily light?dark (LD) cycle. The SCN adopt a stable phase relationship with the LD cycle that, when challenged, results in abrupt or chronic changes in overt rhythms and, in turn, in physiological, behavioral, and metabolic variables. Changes in entrainment, both acute and chronic, may have severe consequences in human performance and pathological outcome. Indeed, animal models of desynchronization have become a useful tool to understand such changes and to evaluate potential treatments in human subjects. Here we review a number of alterations in circadian entrainment, including jet lag, social jet lag (i.e., desynchronization between body rhythms and normal time schedules), shift work, and exposure to nocturnal light, both in human subjects and in laboratory animals. Finally, we focus on the health consequences related to circadian/entrainment disorders and propose a number of approaches for the management of circadian desynchronization.Fil: Chiesa, Juan José. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Duhart, José Manuel. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Casiraghi, Leandro Pablo. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Paladino, Natalia. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Bussi, Ivana Leda. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Golombek, Diego Andrés. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

    How plants handle multiple stresses: hormonal interactions underlying responses to abiotic stress and insect herbivory

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