6,648 research outputs found

    Review of \u3ci\u3eUprising! Woody Crumbo\u27s Indian Art\u3c/i\u3e by Robert Perry

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    In any discussion of important Indian artists of the twentieth century, Woody Crumbo (1912-1989) is a pivotal player. His dynamic figures, brilliant colors, and traditional themes were combined to create a new kind of art. He used traditional art forms and themes from his Potawatomi background as well as themes and incidents from other tribal traditions to inspire his work. Not satisfied with just creating art, Crumbo mentored other artists, and for much of his life he was personally involved in the business of art-creating new opportunities for himself and other Indian artists

    Silicon on Ceramic Process: Silicon Sheet Growth and Device Development for the Large-area Silicon Sheet and Cell Development Tasks of the Low-cost Solar Array Project

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    The technical and economic feasibility of producing solar cell quality sheet silicon was investigated. It was hoped this could be done by coating one surface of carbonized ceramic substrates with a thin layer of large-grain polycrystalline silicon from the melt. Work was directed towards the solution of unique cell processing/design problems encountered with the silicon-ceramic (SOC) material due to its intimate contact with the ceramic substrate. Significant progress was demonstrated in the following areas; (1) the continuous coater succeeded in producing small-area coatings exhibiting unidirectional solidification and substatial grain size; (2) dip coater succeeded in producing thick (more than 500 micron) dendritic layers at coating speeds of 0.2-0.3 cm/sec; and (3) a standard for producing total area SOC solar cells using slotted ceramic substrates was developed

    Abnormally high content of free glucosamine residues identified in a preparation of commercially available porcine intestinal heparan sulfate

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    Heparan sulfate (HS) polysaccharides are ubiquitous in animal tissues as components of proteoglycans, and they participate in many important biological processes. HS carbohydrate chains are complex and can contain rare structural components such as N-unsubstituted glucosamine (GlcN). Commercially available HS preparations have been invaluable in many types of research activities. In the course of preparing microarrays to include probes derived from HS oligosaccharides, we found an unusually high content of GlcN residue in a recently purchased batch of porcine intestinal mucosal HS. Composition and sequence analysis by mass spectrometry of the oligosaccharides obtained after heparin lyase III digestion of the polysaccharide indicated two and three GlcN in the tetrasaccharide and hexasaccharide fractions, respectively. (1)H NMR of the intact polysaccharide showed that this unusual batch differed strikingly from other HS preparations obtained from bovine kidney and porcine intestine. The very high content of GlcN (30%) and low content of GlcNAc (4.2%) determined by disaccharide composition analysis indicated that N-deacetylation and/or N-desulfation may have taken place. HS is widely used by the scientific community to investigate HS structures and activities. Great care has to be taken in drawing conclusions from investigations of structural features of HS and specificities of HS interaction with proteins when commercial HS is used without further analysis. Pending the availability of a validated commercial HS reference preparation, our data may be useful to members of the scientific community who have used the present preparation in their studies

    Mapping the cellular electrophysiology of rat sympathetic preganglionic neurones to their roles in cardiorespiratory reflex integration:A whole cell recording study in situ

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    Sympathetic preganglionic neurones (SPNs) convey sympathetic activity flowing from the CNS to the periphery to reach the target organs. Although previous in vivo and in vitro cell recording studies have explored their electrophysiological characteristics, it has not been possible to relate these characteristics to their roles in cardiorespiratory reflex integration. We used the working heart–brainstem preparation to make whole cell patch clamp recordings from T3–4 SPNs (n = 98). These SPNs were classified by their distinct responses to activation of the peripheral chemoreflex, diving response and arterial baroreflex, allowing the discrimination of muscle vasoconstrictor-like (MVC(like), 39%) from cutaneous vasoconstrictor-like (CVC(like), 28%) SPNs. The MVC(like) SPNs have higher baseline firing frequencies (2.52 ± 0.33 Hz vs. CVC(like) 1.34 ± 0.17 Hz, P = 0.007). The CVC(like) have longer after-hyperpolarisations (314 ± 36 ms vs. MVC(like) 191 ± 13 ms, P < 0.001) and lower input resistance (346 ± 49  MΩ vs. MVC(like) 496 ± 41 MΩ, P < 0.05). MVC(like) firing was respiratory-modulated with peak discharge in the late inspiratory/early expiratory phase and this activity was generated by both a tonic and respiratory-modulated barrage of synaptic events that were blocked by intrathecal kynurenate. In contrast, the activity of CVC(like) SPNs was underpinned by rhythmical membrane potential oscillations suggestive of gap junctional coupling. Thus, we have related the intrinsic electrophysiological properties of two classes of SPNs in situ to their roles in cardiorespiratory reflex integration and have shown that they deploy different cellular mechanisms that are likely to influence how they integrate and shape the distinctive sympathetic outputs

    Divergence in Dialogue

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    Copyright: 2014 Healey et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.This work was supported by the Economic and Social Research Council (ESRC; http://www.esrc.ac.uk/) through the DynDial project (Dynamics of Conversational Dialogue, RES-062-23-0962) and the Engineering and Physical Sciences Research Council (EPSRC; http://www.epsrc.ac.uk/) through the RISER project (Robust Incremental Semantic Resources for Dialogue, EP/J010383/1). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript

    Probing the cosmological variation of the fine-structure constant: Results based on VLT-UVES sample

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    Development of fundamental physics relies on the constancy of various fundamental quantities such as the fine structure constant. Detecting or constraining the possible time variations of these fundamental physical quantities is an important step toward a complete understanding of basic physics. Here we present the results from a detailed many-multiplet analysis performed using high signal-to-noise ratio, high spectral resolution observations of 23 Mg II systems detected toward 18 QSOs in the redshift range 0.4<z<2.3 obtained using UVES at the VLT. We validate our procedure and define the selection criteria that will avoid possible systematics using detail analysis of simulated data set. We show our Voigt profile fitting code recovers the variation in \alpha very accurately when we use single component systems and multiple component systems that are not heavily blended. Spurious detections are frequently seen when we use heavily blended systems or the systems with very weak lines. Thus we avoided heavily blended systems and the systems with Fe II column density < 2x10^12 cm^-2 in the analysis. All steps involved in the analysis are presented in detail. The weighted mean value of the variation in \alpha obtained from our analysis over the redshift range 0.4<z<2.3 is {\Delta\alpha/\alpha} = (-0.06+/-0.06)x10^-5. The median redshift of our sample is 1.55 the 3\sigma upper limit on the time variation of α\alpha is -2.5x10^-16 yr^-1< (\Delta\alpha/\alpha\Delta t) <+1.2x10^-16 yr^-1. To our knowledge this is the strongest constraint from quasar absorption line studies till date.Comment: 23 pages; A&A style, 15 figures, accepte

    Chasing the 400 kyr pacing of deep-marine sandy submarine fans: Middle Eocene Ainsa Basin, Spanish Pyrenees

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    In an attempt to understand the relative importance of climate and tectonics in modulating coarse-grained sediment flux to a tectonically active basin during what many researchers believe to be a greenhouse period, we have studied the Middle Eocene deep-marine Aínsa Basin, Spanish Pyrenees. We use orbital tuning of many spectral gamma-ray-logged fine-grained siliciclastic sections, already shown to contain Milankovitch frequencies, in conjunction with a new high-resolution palaeomagnetic study through the basin sediments, to identify polarity reversals in the basin as anchor points to allow the conversion of a depth-stratigraphy to a chronostratigraphy. We use these data, in conjunction with a new age model incorporating new biostratigraphic data, to pace the development of the deep-marine sandy submarine fans over c. 8 million years. Timing for the sandy submarine fans shows that, unlike for the fine-grained interfan sediments, coarse-grained delivery to the basin was more complex. Approximately 72% of the sandy fans are potentially coincident with the long-eccentricity (400 kyr) minima and, therefore, potentially recording changing climate. The stratigraphic position of some sandy fans is at variance with this, specifically those that likely coincide with a period of known increased tectonic activity within the Aínsa Basin, which we propose represents the time when the basin was converted into a thrust-top basin (Gavarnie thrust sheet), presumably associated with rapid uplift and redeposition of coarse clastics into deep-marine environments. We also identify sub-Milankovitch climate signals such as the c. 41.5 Ma Late Lutetian Thermal Maximum. This study demonstrates the complex nature of drivers on deep-marine sandy fans in a tectonically active basin over c. 8 Myr. Findings of this study suggest that, even during greenhouse periods, sandy submarine fans are more likely linked with times of eccentricity minima and climate change, broadly consistent with the concept of lowstand fans. However, hysteresis effects in orogenic processes of mountain uplift, erosion and delivery of coarse siliciclastics via fluvial systems to coastal (deltaic) and shallow-marine environments likely contributed to the complex signals that we recognize, including the 2–3 Myr time gap between the onset of deep-marine fine-grained sediments in the early development of the Aínsa Basin and the arrival of the first sandy fans

    FloraGuard: tackling the online illegal trade in endangered plants through a cross-disciplinary ICT-enabled methodology.

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    This article presents a part of the ongoing Economic and Social Research Council (ESRC)-funded project “FloraGuard: Tackling the illegal trade in endangered plants” that relies on cross-disciplinary approaches to analyze online marketplaces for the illegal trade in endangered plants, and explores strategies to develop digital resources to assist law enforcement in countering and disrupting this criminal market. This contribution focuses on how the project brought together computer science, criminology, conservation science, and law enforcement expertise to create a tool for the automatic gathering of relevant online information to be used for research, intelligence, and investigative purposes. The article also discusses the ethical standards applied and proposes the concept of “artificial intelligence (AI) review” to provide a sociotechnical solution that builds trustworthiness in the AI approaches used for this type of cross-disciplinary information and communications technology (ICT)-enabled methodology
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