284 research outputs found
The niche construction perspective: A critical appraisal
Niche construction refers to the activities of organisms that bring about changes in their environments, many of which are evolutionarily and ecologically consequential. Advocates of niche construction theory (NCT) believe that standard evolutionary theory fails to recognize the full importance of niche construction, and consequently propose a novel view of evolution, in which niche construction and its legacy over time (ecological inheritance) are described as evolutionary processes, equivalent in importance to natural selection. Here, we subject NCT to critical evaluation, in the form of a collaboration between one prominent advocate of NCT, and a team of skeptics. We discuss whether niche construction is an evolutionary process, whether NCT obscures or clarifies how natural selection leads to organismal adaptation, and whether niche construction and natural selection are of equivalent explanatory importance. We also consider whether the literature that promotes NCT overstates the significance of niche construction, whether it is internally coherent, and whether it accurately portrays standard evolutionary theory. Our disagreements reflect a wider dispute within evolutionary theory over whether the neo-Darwinian synthesis is in need of reformulation, as well as different usages of some key terms (e.g. evolutionary process)
Latest results on Jovian disk X-rays from XMM-Newton
We present the results of a spectral study of the soft X-ray emission
(0.2-2.5 keV) from low-latitude (`disk') regions of Jupiter. The data were
obtained during two observing campaigns with XMM-Newton in April and November
2003. While the level of the emission remained approximately the same between
April and the first half of the November observation, the second part of the
latter shows an enhancement by about 40% in the 0.2-2.5 keV flux. A very
similar, and apparently correlated increase, in time and scale, was observed in
the solar X-ray and EUV flux.
The months of October and November 2003 saw a period of particularly intense
solar activity, which appears reflected in the behaviour of the soft X-rays
from Jupiter's disk. The X-ray spectra, from the XMM-Newton EPIC CCD cameras,
are all well fitted by a coronal model with temperatures in the range 0.4-0.5
keV, with additional line emission from Mg XI (1.35 keV) and Si XIII (1.86
keV): these are characteristic lines of solar X-ray spectra at maximum activity
and during flares.
The XMM-Newton observations lend further support to the theory that Jupiter's
disk X-ray emission is controlled by the Sun, and may be produced in large part
by scattering, elastic and fluorescent, of solar X-rays in the upper atmosphere
of the planet.Comment: 17 pages, 7 figures, accepted for publication in a special issue of
Planetary and Space Scienc
Quantum Disordered Regime and Spin Gap in the Cuprate Superconductors
We discuss the crossover from the quantum critical, , to the quantum
disordered regime in high-T materials in relation to the experimental data
on the nuclear relaxation, bulk susceptibility, and inelastic neutron
scattering. In our scenario, the spin excitations develop a gap
well above T, which is supplemented by the
quasiparticle gap below T. The above experiments yield consistent estimates
for the value of the spin gap, which increases as the correlation length
decreases.Comment: 14 pages, REVTeX v3.0, PostScript file for 3 figures is attached,
UIUC-P-93-07-06
Recent Experimental Tests of Special Relativity
We review our recent Michelson-Morley (MM) and Kennedy-Thorndike (KT)
experiment, which tests Lorentz invariance in the photon sector, and report
first results of our ongoing atomic clock test of Lorentz invariance in the
matter sector. The MM-KT experiment compares a cryogenic microwave resonator to
a hydrogen maser, and has set the most stringent limit on a number of
parameters in alternative theories to special relativity. We also report first
results of a test of Lorentz invariance in the SME (Standard Model Extension)
matter sector, using Zeeman transitions in a laser cooled Cs atomic fountain
clock. We describe the experiment together with the theoretical model and
analysis. Recent experimental results are presented and we give a first
estimate of components of the parameters of the SME matter
sector. A full analysis of systematic effects is still in progress, and will be
the subject of a future publication together with our final results. If
confirmed, the present limits would correspond to first ever measurements of
some components, and improvements by 11 and 14 orders of
magnitude on others.Comment: 29 pages. Contribution to Springer Lecture Notes, "Special Relativity
- Will it survive the next 100 years ?", Proceedings, Potsdam, 200
Functional diversity of chemokines and chemokine receptors in response to viral infection of the central nervous system.
Encounters with neurotropic viruses result in varied outcomes ranging from encephalitis, paralytic poliomyelitis or other serious consequences to relatively benign infection. One of the principal factors that control the outcome of infection is the localized tissue response and subsequent immune response directed against the invading toxic agent. It is the role of the immune system to contain and control the spread of virus infection in the central nervous system (CNS), and paradoxically, this response may also be pathologic. Chemokines are potent proinflammatory molecules whose expression within virally infected tissues is often associated with protection and/or pathology which correlates with migration and accumulation of immune cells. Indeed, studies with a neurotropic murine coronavirus, mouse hepatitis virus (MHV), have provided important insight into the functional roles of chemokines and chemokine receptors in participating in various aspects of host defense as well as disease development within the CNS. This chapter will highlight recent discoveries that have provided insight into the diverse biologic roles of chemokines and their receptors in coordinating immune responses following viral infection of the CNS
Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif
Optimization of the sulfonamide-based kappa opioid receptor (KOR) antagonist probe molecule ML140 through constraint of the sulfonamide nitrogen within a tetrahydroisoquinoline moiety afforded a marked increase in potency. This strategy, when combined with additional structure-activity relationship exploration, has led to a compound only six-fold less potent than norBNI, a widely utilized KOR antagonist tool compound, but significantly more synthetically accessible. The new optimized probe is suitably potent for use as an in vivo tool to investigate the therapeutic potential of KOR antagonists
CPT, T, and Lorentz Violation in Neutral-Meson Oscillations
Tests of CPT and Lorentz symmetry using neutral-meson oscillations are
studied within a formalism that allows for indirect CPT and T violation of
arbitrary size and is independent of phase conventions. The analysis is
particularly appropriate for studies of CPT and T violation in oscillations of
the heavy neutral mesons D, B_d, and B_s. The general Lorentz- and CPT-breaking
standard-model extension is used to derive an expression for the parameter for
CPT violation. It varies in a prescribed way with the magnitude and orientation
of the meson momentum and consequently also with sidereal time. Decay
probabilities are presented for both uncorrelated and correlated mesons, and
some implications for experiments are discussed.Comment: 11 pages, references added, accepted in Physical Review
Green functions for generalized point interactions in 1D: A scattering approach
Recently, general point interactions in one dimension has been used to model
a large number of different phenomena in quantum mechanics. Such potentials,
however, requires some sort of regularization to lead to meaningful results.
The usual ways to do so rely on technicalities which may hide important
physical aspects of the problem. In this work we present a new method to
calculate the exact Green functions for general point interactions in 1D. Our
approach differs from previous ones because it is based only on physical
quantities, namely, the scattering coefficients, and , to construct .
Renormalization or particular mathematical prescriptions are not invoked. The
simple formulation of the method makes it easy to extend to more general
contexts, such as for lattices of general point interactions; on a line; on
a half-line; under periodic boundary conditions; and confined in a box.Comment: Revtex, 9 pages, 3 EPS figures. To be published in PR
The Cerenkov effect revisited: from swimming ducks to zero modes in gravitational analogs
We present an interdisciplinary review of the generalized Cerenkov emission
of radiation from uniformly moving sources in the different contexts of
classical electromagnetism, superfluid hydrodynamics, and classical
hydrodynamics. The details of each specific physical systems enter our theory
via the dispersion law of the excitations. A geometrical recipe to obtain the
emission patterns in both real and wavevector space from the geometrical shape
of the dispersion law is discussed and applied to a number of cases of current
experimental interest. Some consequences of these emission processes onto the
stability of condensed-matter analogs of gravitational systems are finally
illustrated.Comment: Lecture Notes at the IX SIGRAV School on "Analogue Gravity" in Como,
Italy from May 16th-21th, 201
Probing Lorentz and CPT violation with space-based experiments
Space-based experiments offer sensitivity to numerous unmeasured effects
involving Lorentz and CPT violation. We provide a classification of clock
sensitivities and present explicit expressions for time variations arising in
such experiments from nonzero coefficients in the Lorentz- and CPT-violating
Standard-Model Extension.Comment: 15 page
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