Post-COVID symptoms in EU cross-border cooperation

The COVID-19 pandemic has changed the conditions of normal life in many aspects. However, it most impacted the life of people around national borders. What is more, while in other regions, after the successful vaccination campaigns, life begins to return normal, the borderlands still display signs of the effect of the pandemic, what we could call post-COVID symptoms. The study points out the symptoms which seem likely to stay with us for a long time and formulates recommendations for treatment.info:eu-repo/semantics/publishedVersio

Concrétions avec contre-empreinte des gravures de Teyjat

Bourrinet J., Peyrony D. Concrétions avec contre-empreinte des gravures de Teyjat. In: Bulletins et Mémoires de la Société d'anthropologie de Paris, V° Série. Tome 9, 1908. pp. 6-8

The French pioneering role

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Cohesion policy contributing to territorial cohesion: Scenarios

This paper first discusses the present and uncertain future of EU Cohesion policy. The Barca Report argues for all developmental policies, including EU Cohesion policy, to be place-based. This makes for territorial cohesion becoming an important element in the equation. Territory is after all the arena in which households and businesses and public authorities interact. It is thus a platform for co-ordinating public and private actors and their sometimes disparate approaches. Since the future is uncertain, rather than making any predictions, the paper then outlines four scenarios building on the ESPON scenario study2. This latter study concerns a ‘baseline’, a ‘competitiveness-oriented’ and a ‘cohesion-oriented’ scenario after which it constructs a ‘roll back’ scenario representing a vision of Europe developing according to principles enunciated in the European Spatial Development Perspective (ESDP). Whilst the scenarios in this paper do not exactly correspond to the ESPON scenarios, the authors nevertheless recognise the influence on their thinking of this important study.OTB ResearchOTB Research Institute for the Built Environmen

A propos de Glozel

Bosch-Gimpera P., Favret P.-M, Forrer Robert, Hamal-Nandrin J., Peyrony D., Pittard Eugène, Garrod Dorothy. A propos de Glozel. In: Bulletin de la Société préhistorique de France, tome 24, n°12, 1927. pp. 437-456

Real-life epidemiology and current outcomes of hospitalized adults with invasive fungal infections

We aimed to describe the current epidemiology of both hosts with invasive fungal infections (IFI) and causative fungi. And detail outcomes of these infections at 12 weeks in a real-life cohort of hospitalized patients. The study was retrospective and observational to describe IFI diagnosed in a tertiary hospital (February 2017 - December 2021). We included all consecutive patients meeting criteria for proven or probable IFI according to EORTC-MSG and other criteria. A total of 367 IFI were diagnosed. 11.7% were breakthrough infections, and 56.4% were diagnosed in the intensive care unit (ICU). Corticosteroid use (41.4%) and prior viral infection (31.3%) were the most common risk factors for IFI. Lymphoma and pneumocystis pneumonia were the most common baseline and fungal diseases. Only 12% of IFI occurred in patients with neutropenia. Fungal cultures were the most important diagnostic tests (85.8%). The most frequent IFI were candidemia (42.2%) and invasive aspergillosis (26.7%). Azole-resistant candida strains and non-fumigatus aspergillus infection represented 36.1% and 44.5% of the cases, respectively. Pneumocystosis (16.9%), cryptococcosis (4.6%) and mucormycosis (2.7%) were also frequent, as well as mixed infections (3.4%). Rare fungi accounted for 9.5% of infections. Overall IFI mortality at 12 weeks was 32.2%; higher rates were observed for Mucorales (55.6%), Fusarium (50%) and mixed infections (60%). We documented emerging changes in both hosts and real-life IFI epidemiology. Physicians should be aware of these changes to suspect infections and be aggressive in diagnoses and treatments. Currently, outcomes for such clinical scenarios remain extremely poor.© The Author(s) 2023. Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology

Assessing site formation and assemblage integrity through stone tool refitting at Gruta da Oliveira (Almonda karst system, Torres Novas, Portugal): A Middle Paleolithic case study

International audienc

Severe atypical pneumonia in critically ill patients: a retrospective multicenter study

International audienceBackground: Chlamydophila pneumoniae (CP) and Mycoplasma pneumoniae (MP) patients could require intensive care unit (ICU) admission for acute respiratory failure.Methods: Adults admitted between 2000 and 2015 to 20 French ICUs with proven atypical pneumonia were retrospectively described Patients with MP were compared to Streptococcus pneumoniae (SP) pneumonia patients admitted to ICUs.Results: A total of 104 patients were included, 71 men and 33 women, with a median age of 56[44-67] years. MP was the causative agent for 76(73%) patients and CP for 28(27%) patients. Co-infection was documented for 18 patients (viruses for 8[47%] patients). Median number of involved quadrants on chest X-ray was 2[1-4], with alveolar opacities (n = 61,75%), interstitial opacities (n = 32,40%). Extra-pulmonary manifestations were present in 34 (33%) patients. Mechanical ventilation was required for 75(72%) patients and vasopressors for 41(39%) patients. ICU length of stay was 16.5[9.5-30.5] days, and 11(11%) patients died in the ICU. Compared with SP patients, MP patients had more extensive interstitial pneumonia, fewer pleural effusion, and a lower mortality rate [6(8%) vs. 17(22%), p = 0.013]. According MCA analysis, some characteristics at admission could discriminate MP and SP.MP was more often associated with hemolytic anemia, abdominal manifestations, and extensive chest radiograph abnormalities. SP-P was associated with shock, confusion, focal crackles, and focal consolidation.Conclusion: In this descriptive study of atypical bacterial pneumonia requiring ICU admission, mortality was 11%. The comparison with SP pneumonia identified clinical, laboratory, and radiographic features that may suggest MP or CP pneumonia