Diagnostics of evolution of risk collapse complications at student group with anomalous cardiovascular reaction

The description of investigation of predisposition to potential danger of collapse complications at 429 first-year students during physical training is presented using the analysis of pulse wave form. With the help of developed device the group of students with predisposition to risk of collapse complications during physical activity has been revealed. The results of clinical examination have confirmed the predisposition of the given group to risk of collapse complication

Definition of recessive mutations of Blad, Cvm and Bs in population of cattle of the lactic direction of Republic of Belarus

Intensive selection on increase in lactic efficiency, and use of import genetic material in breeding livestock production of Republic of Belarus led to distribution of genetic mutations, which cause death, and frailty of young growth. Detection of genetic anomalies at animals is obligatory, without exception at them lethal mutations sale of breeding bull-calves is impossible. Molecular and genetic methods allow revealing genetic anomalies at the level of DNA such as CVM, BLAD, BS at early age. Identification of undesirable alleles will allow excluding from process of reproduction of carriers of diseases and a message selection on an elimination of mutations. In work, the technique of definition of recessive mutations is pr esented to populations of cattle of the lactic direction of Republic of Belarus. The characteristic of genetic structure of the studied population is given.Интенсивная селекция на увеличение молочной продуктивности, а также использование импортного генетического материала в племенном животноводстве Республики Беларусь привела к распространению генетических мутаций, которые вызывают гибель и нежизнеспособность молодняка. Выявление генетических аномалий у животных обязательно, т.к. без исключения у них летальных мутаций продажа племенных бычков невозможна. Молекулярно-генетические методы позволяют выявлять генетические аномалии на уровне ДНК, такие как CVM, BLAD, BS в раннем возрасте. Выявление нежелательных аллелей позволит исключить из процесса воспроизводства носителей заболеваний и вести селекцию на элиминацию мутаций. В статье представлена методика определения рецессивных мутаций у животных белорусской черно-пестрой породы и популяции голштинизированного черно-пестрого скота Республики Беларусь. Дана характеристика генетической структуры изучаемой популяции

Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.

BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362

PROSPECTS OF COAL MINE METHANE UTILIZATION

During coal mining methane is extracted to the surface by degassing, ventilation, and gas release control systems. Methane is a greenhouse gas, but at the same time is suitable for beneficial use. The article estimates the volumes of methane emissions that accompany underground coal mining, the concentrations of methane in the methane-air mixture depending on the types of emission sources. The paper considers the major aspects and possible ways of utilizing coal mine methane for producing useful products, heat and electric energy, as well as motor fuel

Effect of Mechanical Load on Defects Level in Soft Ferrite Ceramics

The article presents the results of a study of the effect of mechanical load on the temperature dependence of the initial permeability of LiTiZn soft ferrite ceramics. Regimes of mechanical load were created by a steel non-magnetic ring with screws. In this work, four levels of mechanical load were investigated: without load, with 1, 2 and 3 screws. For obtaining temperature dependences and exclude the influence of prehistory on the initial permeability, the samples were heated to a temperature exceeding the Curie point by 50 degrees, after which they slowly cooled to room temperature. The defects level was determined by the ratio of the parameters β / α of the phenomenological expression, which describes the experimental temperature dependences. It is shown that as the mechanical load increases, the defects level of ferrite ceramics increases, and after load removing, it returns to its original level

Effect of Mechanical Load on Defects Level in Soft Ferrite Ceramics

The article presents the results of a study of the effect of mechanical load on the temperature dependence of the initial permeability of LiTiZn soft ferrite ceramics. Regimes of mechanical load were created by a steel non-magnetic ring with screws. In this work, four levels of mechanical load were investigated: without load, with 1, 2 and 3 screws. For obtaining temperature dependences and exclude the influence of prehistory on the initial permeability, the samples were heated to a temperature exceeding the Curie point by 50 degrees, after which they slowly cooled to room temperature. The defects level was determined by the ratio of the parameters β / α of the phenomenological expression, which describes the experimental temperature dependences. It is shown that as the mechanical load increases, the defects level of ferrite ceramics increases, and after load removing, it returns to its original level

Nanometals in energetic systems: Achievements and future

The characterization of nanometals that are mostly produced by electrical explosion of wires and a comprehensive survey of their usage in different energetic systems are presented. The greatest attention is devoted to nanoaluminum, which is the most common representative of nanometals. The improved kinetic characteristics of chemically reacting systems typical for nanometals (such as burning and detonation rate enhancement for propellants, explosives, and thermites) are studied, and novel paths for chemical reactions are opened (such as nitrides formation in oxygenated media and the catalytic effect on the decomposition of energetic materials). A poor correlation between the powder properties and the slow oxidation parameters was found as a result of very wide scatter in the nanometals characteristics. The burning rate enhancement factor (K) was analyzed for nanoaluminum-loaded solid propellants. The most promising energetic systems are nanometal-loaded solid fuels that are HTPB and ice based with chemically inert matrices