235 research outputs found

    “Freezing” the left ventricular outflow tract for homograft reconstruction in aortic root endocarditis

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    Las audiencias virtuales y sus implicancias en los delitos de omisión alimentaria en el Distrito Judicial del Callao, 2021

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    En el presente trabajo de investigación titulada “Las Audiencias Virtuales y sus Implicancias en los Delitos de Omisión Alimentaria en el Distrito Judicial del Callao, 2021”. Teniendo como objetivo principal, Analizar si se garantiza el acceso a la justicia, a través de las audiencias virtuales en los delitos por omisión alimentaria en el distrito judicial del Callao, 2021. En el presente trabajo de investigación se realizó teniendo en cuenta el enfoque cualitativo de tipo de investigación básica y con un diseño interpretativo basado en la teoría fundamentada que buscó analizar y fundamentar las categorías consignadas en la investigación además se hizo uso del instrumento de la guía de entrevista, que contiene nueve preguntas, siendo validados por expertos y dirigidos a una categorización de sujetos. Se concluye que el acceso a la justicia a través de las audiencias virtuales no se ve vulnerado en los delitos de omisión alimentaria en el distrito judicial del Callao, 2021

    Minimally-Invasive Surgery of Mitral Valve. State of the Art

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    Minimally-invasive mitral valve surgery has been in development during the last thirty years and now allows to perform mitral and tricuspid interventions, coronary bypass surgery, repair of congenital heart defects and more. Current state-of-the-art technology and clinical knowledge make possible to offer this approach in expert centers to a growing number of patients, who benefit from its advantages. Minimally-invasive mitral surgery is becoming the best option to repair que mitral valve and patients are able to recover better and faster than after conventional surgery without compromising quality of the repair. With the aid of high-definition 3D visualization and specifically designed instruments, including robotic telemanipulation, thoracoscopic and robotic surgery performed this way require only small incisions in the right chest. In the present chapter we will expose the current state of this field, going into detail regarding patient selection and operative techniques, and also reviewing the requirements for building a successful program

    Heart Transplant after Mechanical Circulatory Support

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    Heart transplant is the gold-standard treatment for end-stage heart failure. However, the aging of the population, increase in the prevalence of heart failure and the shortage of available donors have led to a significant increase in the wait-list times. This increase in waiting time may cause some patients clinically deteriorate while on the list. Several bridging strategies have been developed to help patients reach heart transplant. It is mandatory to know the current results of these techniques and the specific tips and tricks these different devices may have. Survival results would also be presented to help us decide the best strategy for each of our patients

    Neurohormonal Modulation as a Therapeutic Target in Pulmonary Hypertension.

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    The autonomic nervous system (ANS) and renin-angiotensin-aldosterone system (RAAS) are involved in many cardiovascular disorders, including pulmonary hypertension (PH). The current review focuses on the role of the ANS and RAAS activation in PH and updated evidence of potential therapies targeting both systems in this condition, particularly in Groups 1 and 2. State of the art knowledge in preclinical and clinical use of pharmacologic drugs (beta-blockers, beta-three adrenoceptor agonists, or renin-angiotensin-aldosterone signaling drugs) and invasive procedures, such as pulmonary artery denervation, is provided.This work was partially funded by Fondo Europeo de Desarrollo Regional (FEDER) Instituto de Salud Carlos III-Fondo de Investigación Sanitaria PI17/00995 and Intensificación AES2019 to Dr. García-Álvarez. The CNIC is supported by the Ministerio de Ciencia, Innovación y Universidades and the Pro CNIC Foundation, and is a Severo Ochoa Center of Excellence (SEV-2015-0505). Part of this work was developed at the Centre de Recerca Biomèdica Cellex, IDIBAPS, Barcelona. The IDIBAPS belongs to the CERCA Programme and receives partial funding from the Generalitat de Catalunya.S

    Exploring Quality in English-Spanish Conference Interpreting from a Communicative and Dual Perspective: User and Interpreter Views.

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    El presente trabajo busca identificar las concepciones de calidad de los destinatarios e intérpretes para determinar la relación entre las necesidades de los destinatarios y los principios de calidad de los intérpretes. Para ello, se tomó como referencia las dimensiones de interpretación de Pöchhacker (2013) y el modelo comunicativo de Angelelli (2000). El estudio se realizó en siete conferencias con interpretación simultánea (inglés-español) en Lima, Perú entre agosto de 2018 y junio de 2019. Se empleó una metodología mixta: diez entrevistas a los intérpretes y 86 cuestionarios aplicados a ambos participantes, que contaron con dos escalas de valoración de once criterios lingüísticos y extralingüísticos. Los destinatarios e intérpretes coincidieron en la valoración positiva de pronunciación correcta, fluidez y seguridad en la voz; por el contrario, difirieron en la valoración de la fidelidad y el uso correcto de los términos. Se revela que los componentes comunicativos de Angelelli y la situación real impactaron en las concepciones de calidad de ambos actores.This paper aims to identify users’ and interpreters’ perspectives on interpretation quality to determine the relationship between users’ needs and interpreters’ quality principles. Pöchhacker’s (2013) dimensions of interpreting and Angelelli’s (2000) communication model were thus taken as a reference. The study was carried out in seven conferences with simultaneous interpreting in Lima, Peru between August 2018 and June 2019. 10 interviews were conducted with interpreters and 86 questionnaires with two ranking-order scales of 11 linguistic and extralinguistic criteria were administered to users and interpreters. The results show that the respondents agreed on the positive rating of correct pronunciation, fluency, and confident voice. However, they differed in the rating of sense consistency and use of correct terminology. It is revealed that Angelelli’s speech components and the real context had an impact on users’ and interpreters’ perspectives on quality

    Complex Politics: A Quantitative Semantic and Topological Analysis of UK House of Commons Debates

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    This study is a first, exploratory attempt to use quantitative semantics techniques and topological analysis to analyze systemic patterns arising in a complex political system. In particular, we use a rich data set covering all speeches and debates in the UK House of Commons between 1975 and 2014. By the use of dynamic topic modeling (DTM) and topological data analysis (TDA) we show that both members and parties feature specific roles within the system, consistent over time, and extract global patterns indicating levels of political cohesion. Our results provide a wide array of novel hypotheses about the complex dynamics of political systems, with valuable policy applications

    Immediate and Legacy Effects of Urban Pollution on River Ecosystem Functioning: a Mesocosm Experiment

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    Effluents from urban wastewater treatment plants (WWTP) consist of complex mixtures of substances that can affect processes in the receiving ecosystems. Some of these substances (toxic contaminants) stress biological activity at all concentrations, while others (e.g., nutrients) subsidize it at low concentrations and stress it above a threshold, causing subsidy-stress responses. Thus, the overall effects of WWTP effluents depend mostly on their composition and the dilution capacity of the receiving water bodies. We assessed the immediate and legacy effects of WWTP effluents in artificial streams, where we measured the uptake of soluble reactive phosphorus (SRP) by the biofilm, biomass accrual, benthic metabolism and organic matter decomposition (OMD). In a first phase (32 d), the channels were subjected to a gradient of effluent contribution, from pure stream water to pure effluent. WWTP effluent affected the ecosystem processes we measured, although we found no clear subsidy-stress patterns except for biofilm biomass accrual. Instead, most of the processes were subsidized, although they showed complex and process-specific patterns. Benthic metabolism and OMD were subsidized without saturation, as they peaked at medium and high levels of pollution, respectively, but they never fell below control levels. SRP uptake was the only process that decreased with increasing effluent concentration. In a second phase of the experiment (23 d), all channels were kept on pure stream water to analyse the legacy effects of the effluent. For most of the processes, there were clear legacy effects, which followed either subsidy, stress, or subsidy-stress patterns. SRP uptake capacity was stressed with increasing pollution legacy, whereas algal accrual and benthic metabolism continued being subsidized. Conversely, biofilm biomass accrual and OMD showed no legacy effects. Overall, the WWTP effluent caused complex and process-specific responses in our experiment, mainly driven by the mixed contribution of subsidizers and stressors. These results help improving our understanding of the effects of urban pollution on stream ecosystem functioning. Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.This research was supported by the European Union 7th Framework Programme (GLOBAQUA; 603629-ENV-2013-6.2.1). Authors also acknowledge the financial support from the University of the Basque Country (pre-doctoral fellowship to O. Pereda), the Basque Government (Consolidated Research Group: Stream Ecology 7-CA-18/10), and the Economy and Knowledge Department of the Catalan Government (Consolidated Research Group: ICRA-ENV 2017 SGR 1124). Authors are also especially grateful to Maria Casellas, Carme Font, Carmen Gutiérrez, Ferran Romero and Laia Sabater-Liesa for their assistance during the laboratory experiments
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