2,953 research outputs found

    Decision-making and problem-solving methods in automation technology

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    The state of the art in the automation of decision making and problem solving is reviewed. The information upon which the report is based was derived from literature searches, visits to university and government laboratories performing basic research in the area, and a 1980 Langley Research Center sponsored conferences on the subject. It is the contention of the authors that the technology in this area is being generated by research primarily in the three disciplines of Artificial Intelligence, Control Theory, and Operations Research. Under the assumption that the state of the art in decision making and problem solving is reflected in the problems being solved, specific problems and methods of their solution are often discussed to elucidate particular aspects of the subject. Synopses of the following major topic areas comprise most of the report: (1) detection and recognition; (2) planning; and scheduling; (3) learning; (4) theorem proving; (5) distributed systems; (6) knowledge bases; (7) search; (8) heuristics; and (9) evolutionary programming

    Conference on Automated Decision-Making and Problem Solving, the Third Day: Issues Discussed

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    A conference held at Langley Research Center in May of 1980 brought together university experts from the fields of Control Theory, Operations Research, and Artificial Intelligence to explore current research in automation from both the perspective of their own particular disciplines and from that of interdisciplinary considerations. Informal discussions from the final day of the those day conference are summarized

    Brain GABA and Glutamate Concentrations Following Chronic Gabapentin Administration: A Convenience Sample Studied During Early Abstinence From Alcohol.

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    Gabapentin (GBP), a GABA analog that may also affect glutamate (Glu) production, can normalize GABA and Glu tone during early abstinence from alcohol, effectively treating withdrawal symptoms and facilitating recovery. Using in vivo magnetic resonance spectroscopy, we tested the degree to which daily GBP alters regional brain GABA and Glu levels in short-term abstinent alcohol-dependent individuals. Regional metabolite levels were compared between 13 recently abstinent alcohol-dependent individuals who had received daily GBP for at least 1 week (GBP+) and 25 matched alcohol-dependent individuals who had not received GBP (GBP-). Magnetic resonance spectra from up to five different brain regions were analyzed to yield absolute GABA and Glu concentrations. GABA and Glu concentrations in the parieto-occipital cortex were not different between GBP- and GBP+. Glu levels in anterior cingulate cortex, dorsolateral prefrontal cortex, and basal ganglia did not differ between GBP- and GBP+. However, in a subgroup of individuals matched on age, sex, and abstinence duration, GBP+ had markedly lower Glu in the frontal white matter (WM) than GBP-, comparable to concentrations found in light/non-drinking controls. Furthermore, lower frontal WM Glu in GBP+ correlated with a higher daily GBP dose. Daily GBP treatment at an average of 1,600 mg/day for at least 1 week was not associated with altered cortical GABA and Glu concentrations during short-term abstinence from alcohol, but with lower Glu in frontal WM. GBP for the treatment of alcohol dependence may work through reducing Glu in WM rather than increasing cortical GABA

    Assessing movements of three buoy line types using DSTmilli Loggers: Implications for entanglements of bottlenose dolphins in the crab pot fishery

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    A study was conducted in October 2006 in the Charleston, South Carolina area to test the movements of three different buoy line types to determine which produced a preferred profile that could reduce the risk of dolphin entanglement. Tests on diamond-braided nylon commonly used in the crab pot fishery were compared with stiffened line of Esterpro and calf types in both shallow and deep water environments using DSTmilli data loggers. Loggers were placed at intervals along the lines to record depth, and thus movements, over a 24 hour period. Three observers viewed video animations and charts created for each of the six trial days from the collected logger data and provided their opinions on the most desirable line type that fit set criteria. A quantitative analysis (ANCOVA) of the data was conducted taking into consideration daily tidal fluctuations and logger movements. Loggers tracking the tides had an r2 value approaching 1.00 and produced little movement other than with the tides. Conversely, r2 values approaching 0.00 were less affected by tidal movement and influenced by currents that cause more erratic movement. Results from this study showed that stiffened line, in particular the medium lay Esterpro type, produced the more desirable profiles that could reduce risk of dolphin entanglement. Combining the observer’s results with the ANCOVA results, Esterpro was chosen nearly 60% of the time as opposed to the nylon line which was only chosen 10% of the time. ANCOVA results showed that the stiffened lines performed better in both the shallow and deep water environments, while the nylon line only performed better during one trial in a deep water set, most probably due to the increased current velocities experienced that day. (58pp.)(PDF contains 68 pages

    Space spider crane

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    A space spider crane for the movement, placement, and or assembly of various components on or in the vicinity of a space structure is described. As permanent space structures are utilized by the space program, a means will be required to transport cargo and perform various repair tasks. A space spider crane comprising a small central body with attached manipulators and legs fulfills this requirement. The manipulators may be equipped with constant pressure gripping end effectors or tools to accomplish various repair tasks. The legs are also equipped with constant pressure gripping end effectors to grip the space structure. Control of the space spider crane may be achieved either by computer software or a remotely situated human operator, who maintains visual contact via television cameras mounted on the space spider crane. One possible walking program consists of a parallel motion walking program whereby the small central body alternatively leans forward and backward relative to end effectors

    No classical limit of quantum decay for broad states

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    Though the classical treatment of spontaneous decay leads to an exponential decay law, it is well known that this is an approximation of the quantum mechanical result which is a non-exponential at very small and large times for narrow states. The non exponential nature at large times is however hard to establish from experiments. A method to recover the time evolution of unstable states from a parametrization of the amplitude fitted to data is presented. We apply the method to a realistic example of a very broad state, the sigma meson and reveal that an exponential decay is not a valid approximation at any time for this state. This example derived from experiment, shows the unique nature of broad resonances

    Building the Full Fermion-Photon Vertex of QED by Imposing Multiplicative Renormalizability of the Schwinger-Dyson Equations for the Fermion and Photon Propagators

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    In principle, calculation of a full Green's function in any field theory requires knowledge of the infinite set of multi-point Green's functions, unless one can find some way of truncating the corresponding Schwinger-Dyson equations. For the fermion and boson propagators in QED this requires an {\it ansatz} for the full three point vertex. Here we illustrate how the properties of gauge invariance, gauge covariance and multiplicative renormalizability impose severe constraints on this fermion-boson interaction, allowing a consistent truncation of the propagator equations. We demonstrate how these conditions imply that the 3-point vertex {\bf in the propagator equations} is largely determined by the behaviour of the fermion propagator itself and not by knowledge of the many higher point functions. We give an explicit form for the fermion-photon vertex, which in the fermion and photon propagator fulfills these constraints to all orders in leading logarithms for massless QED, and accords with the weak coupling limit in perturbation theory at O(α){\cal O}(\alpha). This provides the first attempt to deduce non-perturbative Feynman rules for strong physics calculations of propagators in massless QED that ensures a more consistent truncation of the 2-point Schwinger-Dyson equations. The generalisation to next-to-leading order and masses will be described in a longer publication.Comment: 57 pages, 3 figure

    The non-perturbative three-point vertex in massless quenched QED and perturbation theory constraints

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    Dong, Munczek and Roberts have shown how the full 3-point vertex that appears in the Schwinger-Dyson equation for the fermion propagator can be expressed in terms of a constrained function W1W_1 in massless quenched QED. However, this analysis involved two key assumptions: that the fermion anomalous dimension vanishes in the Landau gauge and that the transverse vertex has a simplified dependence on momenta. Here we remove these assumptions and find the general form for a new constrained function U1U_1 that ensures the multiplicative renormalizability of the fermion propagator non-perturbatively. We then study the restriction imposed on U1U_1 by recent perturbative calculations of the vertex and compute its leading logarithmic expansion. Since U1U_1 should reduce to this expansion in the weak coupling regime, this should serve as a guide to its non-perturbative construction. We comment on the perturbative realization of the constraints on U1U_1.Comment: 18 pages, Latex, 2 figure

    Therapeutic exploitation of IPSE, a urogenital parasite-derived host modulatory protein, for chemotherapy-induced hemorrhagic cystitis

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    Chemotherapy-induced hemorrhagic cystitis (CHC) can be difficult to manage. Prior work suggests IL-4 alleviates ifosfamide-induced hemorrhagic cystitis (IHC), but systemically administered IL-4 causes significant side effects. We hypothesized that the Schistosoma haematobium homolog of Interleukin-4-inducing principle from Schistosoma mansoni Eggs (H-IPSE), would reduce IHC and associated bladder pathology. IPSE binds IgE on basophils and mast cells, triggering IL-4 secretion by these cells. IPSE is also an “infiltrin”, translocating into the host nucleus to modulate gene transcription. Mice were administered IL-4, H-IPSE protein or its nuclear localization sequence (NLS) mutant with or without neutralizing anti-IL-4 antibody, or MESNA, followed by ifosfamide. Bladder tissue damage and hemoglobin content were measured. Spontaneous and evoked pain, urinary frequency and gene expression were assessed. Pain behaviors were interpreted in a blinded fashion. One dose of H-IPSE was superior to MESNA and IL-4 in suppressing bladder hemorrhage in an IL-4-and NLS-dependent fashion, and comparable to MESNA in dampening ifosfamide-triggered pain behaviors in an NLS-dependent manner. H-IPSE also accelerated urothelial repair following IHC. Our work represents the first therapeutic exploitation of a uropathogen-derived host modulatory molecule in a clinically relevant bladder disease model, and indicates that IPSE may be an alternative to MESNA for mitigating CHC

    Informal Action—Adjudication—Rule Making: Some Recent Developments in Federal Administrative Law

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    Direct energy consumption of ICT hardware is only “half the story.” In order to get the “whole story,” energy consumption during the entire life cycle has to be taken into account. This chapter is a first step toward a more comprehensive picture, showing the “grey energy” (i.e., the overall energy requirements) as well as the releases (into air, water, and soil) during the entire life cycle of exemplary ICT hardware devices by applying the life cycle assessment method. The examples calculated show that a focus on direct energy consumption alone fails to take account of relevant parts of the total energy consumption of ICT hardware as well as the relevance of the production phase. As a general tendency, the production phase is more and more important the smaller (and the more energy-efficient) the devices are. When in use, a tablet computer is much more energy-efficient than a desktop computer system with its various components, so its production phase has a much greater relative importance. Accordingly, the impacts due to data transfer when using Internet services are also increasingly relevant the smaller the end-user device is, reaching up to more than 90 % of the overall impact when using a tablet computer.QC 20140825</p
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