8 research outputs found
Identifying factors influencing contraceptive use in Bangladesh: evidence from BDHS 2014 data
Low temperature surface preparation of GaN substrates for atomic layer epitaxial growth: Assessment of ex situ
Borago officinalis attracts the aphid parasitoid Aphidius colemani (Hymenoptera: Braconidae)
Awareness, use and associated factors of emergency contraceptive pills among women of reproductive age (15-49 years) in Tamale, Ghana
An integrated encyclopedia of DNA elements in the human genome.
The human genome encodes the blueprint of life, but the function of the vast majority of its nearly three billion bases is unknown. The Encyclopedia of DNA Elements (ENCODE) project has systematically mapped regions of transcription, transcription factor association, chromatin structure and histone modification. These data enabled us to assign biochemical functions for 80% of the genome, in particular outside of the well-studied protein-coding regions. Many discovered candidate regulatory elements are physically associated with one another and with expressed genes, providing new insights into the mechanisms of gene regulation. The newly identified elements also show a statistical correspondence to sequence variants linked to human disease, and can thereby guide interpretation of this variation. Overall, the project provides new insights into the organization and regulation of our genes and genome, and is an expansive resource of functional annotations for biomedical research