Wall-temperature effects on the aerodynamics of a hydrogen-fueled transport concept in Mach 8 blowdown and shock tunnels

Results are presented from two separate tests on the same blended wing-body hydrogen fueled transport model at a Mach number of about 8 and a range of Reynolds numbers (based on theoretical body length) of 0.597 x 10 to the 6th power to about 156.22 x 10 to the 6th power. Tests were made in conventional hypersonic blowdown tunnel and a hypersonic shock tunnel at angles of attack of -2 deg to about 8 deg, with an extensive study made at a constant angle of attack of 3 deg. The model boundary-layer flow varied from laminar at the lower Reynolds numbers to predominantly turbulent at the higher Reynolds numbers. Model wall temperatures and stream static temperatures varied widely between the two tests, particularly at the lower Reynolds numbers. These temperature differences resulted in marked variations of the axial-force coefficients between the two tests, due in part to the effects of induced pressure and viscous interaction variations. The normal-force coefficient was essentially independent of Reynolds number. Analysis of results utilized current theoretical computer programs and basic boundary-layer theory

Food Security, Depression and Quality of Life in Northern Plains Indians

Major health disparities, high levels of poverty and food insecurity exist in many Native American and Alaskan Native (AI/AN) communities. Relatively little research has been done on these issues and possible relationships between them. A research program was designed with the objective of exploring the relationships between these various issues, if any existed, in one sub-group of AI/AN. In the study, the incidence of food insecurity was determined in a convenience sample of Northern Plains Indians (NPI) and correlated with measures of physical and mental health, body composition, quality of life, cultural identification and dietary intakes. Participants were 458 adult attendees at summer powwows and health fairs held at 5 reservations and 3 tribal colleges in North Dakota and western Minnesota. Participants completed various measurements and assessments and pertinent health and demographic data were recorded. Observed incidences of “food insecurity” overall and “very low food security” in particular (26.4% and 10.4%, respectively) were in sharp contrast to recently reported rates for North Dakota (8.7% and 3.4%) and the U.S. population as a whole (14.7% and 5.6%). In this manuscript, analysis revealed a positive relationship between food insecurity and depression and a negative relationship between food insecurity and quality of life. The findings emphasize the need to address food insecurity when designing research and service programs to address depression in AI/AN populations

Linear Stochastic Models of Nonlinear Dynamical Systems

We investigate in this work the validity of linear stochastic models for nonlinear dynamical systems. We exploit as our basic tool a previously proposed Rayleigh-Ritz approximation for the effective action of nonlinear dynamical systems started from random initial conditions. The present paper discusses only the case where the PDF-Ansatz employed in the variational calculation is ``Markovian'', i.e. is determined completely by the present values of the moment-averages. In this case we show that the Rayleigh-Ritz effective action of the complete set of moment-functions that are employed in the closure has a quadratic part which is always formally an Onsager-Machlup action. Thus, subject to satisfaction of the requisite realizability conditions on the noise covariance, a linear Langevin model will exist which reproduces exactly the joint 2-time correlations of the moment-functions. We compare our method with the closely related formalism of principal oscillation patterns (POP), which, in the approach of C. Penland, is a method to derive such a linear Langevin model empirically from time-series data for the moment-functions. The predictive capability of the POP analysis, compared with the Rayleigh-Ritz result, is limited to the regime of small fluctuations around the most probable future pattern. Finally, we shall discuss a thermodynamics of statistical moments which should hold for all dynamical systems with stable invariant probability measures and which follows within the Rayleigh-Ritz formalism.Comment: 36 pages, 5 figures, seceq.sty for sequential numbering of equations by sectio

Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice

Culturing retinoblastoma tumor cells in defined stem cell media gives rise to primary tumorspheres that can be grown and maintained for only a limited time. These cultured tumorspheres may exhibit markedly different cellular phenotypes when compared to the original tumors. Demonstration that cultured cells have the capability of forming new tumors is important to ensure that cultured cells model the biology of the original tumor

Sediment compaction rates and subsidence in deltaic plains : numerical constraints and stratigraphic influences

This paper is not subject to U.S. copyright. The definitive version was published in Basin Research 19 (2007): 19-31, doi:10.1111/j.1365-2117.2006.00310.x.Natural sediment compaction in deltaic plains influences subsidence rates and the evolution of deltaic morphology. Determining compaction rates requires detailed knowledge of subsurface geotechnical properties and depositional history, neither of which is often readily available. To overcome this lack of knowledge, we numerically forward model the incremental sedimentation and compaction of stochastically generated stratigraphies with geotechnical properties typical of modern depositional environments in the Mississippi River delta plain. Using a Monte Carlo approach, the range of probable compaction rates for stratigraphies with compacted thicknesses <150 m and accumulation times <20 kyr. varies, but maximum values rarely exceed a few mm yr-1. The fastest compacting stratigraphies are composed primarily of peat and bar sand, whereas the slowest compacting stratigraphies are composed of prodelta mud and natural levee deposits. These results suggest that compaction rates can significantly influence vertical and lateral stratigraphic trends during deltaic evolution

Zinc intake, status and indices of cognitive function in adults and children: a systematic review and meta-analysis

In developing countries, deficiencies of micronutrients are thought to have a major impact on child development; however, a consensus on the specific relationship between dietary zinc intake and cognitive function remains elusive. The aim of this systematic review was to examine the relationship between zinc intake, status and indices of cognitive function in children and adults. A systematic literature search was conducted using EMBASE, MEDLINE and Cochrane Library databases from inception to March 2014. Included studies were those that supplied zinc as supplements or measured dietary zinc intake. A meta-analysis of the extracted data was performed where sufficient data were available. Of all of the potentially relevant papers, 18 studies met the inclusion criteria, 12 of which were randomised controlled trials (RCTs; 11 in children and 1 in adults) and 6 were observational studies (2 in children and 4 in adults). Nine of the 18 studies reported a positive association between zinc intake or status with one or more measure of cognitive function. Meta-analysis of data from the adult’s studies was not possible because of limited number of studies. A meta-analysis of data from the six RCTs conducted in children revealed that there was no significant overall effect of zinc intake on any indices of cognitive function: intelligence, standard mean difference of <0.001 (95% confidence interval (CI) –0.12, 0.13) P=0.95; executive function, standard mean difference of 0.08 (95% CI, –0.06, 022) P=0.26; and motor skills standard mean difference of 0.11 (95% CI –0.17, 0.39) P=0.43. Heterogeneity in the study designs was a major limitation, hence only a small number (n=6) of studies could be included in the meta-analyses. Meta-analysis failed to show a significant effect of zinc supplementation on cognitive functioning in children though, taken as a whole, there were some small indicators of improvement on aspects of executive function and motor development following supplementation but high-quality RCTs are necessary to investigate this further

Understanding equatorial Atlantic interannual variability

An observational-based analysis of coupled variability in the equatorial Atlantic and its seasonality is presented. Regression analysis shows that the three elements of the Bjerknes positive feedback exist in the Atlantic and are spatially similar to those of the Pacific. The cross-correlation functions of the elements of the Bjerknes feedback are also similar and consistent with an ocean–atmosphere coupled mode. However, the growth rate in the Atlantic is up to 50% weaker, and explained variance is significantly lower. The Bjerknes feedback in the Atlantic is strong in boreal spring and summer, and weak in other seasons, which explains why the largest sea surface temperature anomalies (SSTAs) occur in boreal summer. Its seasonality is determined by seasonal variations in both atmospheric sensitivity to SSTA and SSTA sensitivity to subsurface temperature anomalies

Estimating the predictability of an oceanic time series using linear and nonlinear methods

Author Posting. © American Geophysical Union, 2004. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Journal of Geophysical Research 109 (2004): C08002, doi:10.1029/2003JC002148.This study establishes a series of tests to examine the relative utility of nonlinear time series analysis for oceanic data. The performance of linear autoregressive models and nonlinear delay coordinate embedding methods are compared for three numerical and two observational data sets. The two observational data sets are (1) an hourly near-bottom pressure time series from the South Atlantic Bight and (2) an hourly current-meter time series from the Middle Atlantic Bight (MAB). The nonlinear methods give significantly better predictions than the linear methods when the underlying dynamics have low dimensionality. When the dimensionality is high, the utility of nonlinear methods is limited by the length and quality of the time series. On the application side we mainly focus on the MAB data set. We find that the slope velocities are much less predictable than shelf velocities. Predictability on the slope after several hours is no better than the statistical mean. On the other hand, significant predictability of shelf velocities can be obtained for up to at least 12 hours.This research was supported by Office of Naval Research grants N00014-01-1-0260, N00014-92-J-1481, and N10014-99-1-0258

Equatorial Atlantic interannual variability: the role of heat content

The dynamics of the Equatorial Atlantic zonal mode are studied using observed sea surface height (SSH), sea surface temperature (SST), and heat flux and reanalysis wind stress and upper ocean temperature. Principal oscillation pattern (POP) analysis shows that the zonal mode is an oscillatory normal-mode of the observed coupled system, obeying the delayed-action/recharge oscillator paradigm for ENSO. Variations in equatorial averaged SSH, a proxy for upper ocean heat content, precede SST anomalies in the cold tongue by 4-5 months, about a quarter of the POP period. Positive subsurface temperature anomalies appear in the west, as a delayed response to the preceding cold event. These propagate eastward, where due to the shallow thermocline they can influence SST, leading to the next warm event. Although SST variations exhibit weak westward propagation during some zonal mode events, POP analysis indicates that to first order there is no zonal propagation in SST. Net surface heat flux anomalies generally act to damp SST anomalies. The zonal mode explains a large amount (70%) of SST variability in the east and a significant fraction (19%) of equatorial variability. Thus, the predictability potential in the Equatorial Atlantic on seasonal time scales may be considerably higher than currently thought