Augmented reality-assisted ultrasound breast biopsy

Breast cancer is the most prevalent cancer in the world and the fifth-leading cause of cancer-related death. Treatment is effective in the early stages. Thus, a need to screen considerable portions of the population is crucial. When the screening procedure uncovers a suspect lesion, a biopsy is performed to assess its potential for malignancy. This procedure is usually performed using real-time Ultrasound (US) imaging. This work proposes a visualization system for US breast biopsy. It consists of an application running on AR glasses that interact with a computer application. The AR glasses track the position of QR codes mounted on an US probe and a biopsy needle. US images are shown in the user’s field of view with enhanced lesion visualization and needle trajectory. To validate the system, latency of the transmission of US images was evaluated. Usability assessment compared our proposed prototype with a traditional approach with different users. It showed that needle alignment was more precise, with 92.67 ± 2.32° in our prototype versus 89.99 ± 37.49° in a traditional system. The users also reached the lesion more accurately. Overall, the proposed solution presents promising results, and the use of AR glasses as a tracking and visualization device exhibited good performance.This work was funded by the projects “NORTE-01-0145-FEDER-000045” and “NORTE-01- 0145-FEDER-000059", supported by Northern Portugal Regional Operational Programme (NORTE 2020), under the Portugal 2020 Partnership Agreement, through the European Regional Development Fund (FEDER). It was also funded by national funds, through the FCT (Fundação para a Ciência e a Tecnologia) and FCT/MCTES in the scope of the project UIDB/05549/2020, UIDP/05549/2020 and LASI-LA/P/0104/2020. The authors also acknowledge FCT, Portugal and the European Social Found, European Union, for funding support through the “Programa Operacional Capital Humano” (POCH) in the scope of the PhD grants SFRH/BD/136721/2018 (Oliveira B.) and SFRH/BD/136670 (Torres H. R.)

Composição bioquímica e potencial biológico do fruto de ora-pro-nóbis: uma visão geral

Exotic fruit crops, such as ora-pro-nobis, play an important role in human nutrition, making them an excellent base for low-calorie diets. Recent research has shown that ora-pro-nobis fruit is rich in many nutritional and bioactive compounds, making it highly valued for its unique taste, aroma, and color. As the popularity of this fruit grows in economic markets, it is important to have a comprehensive reference for its nutritional and bioactive benefits. This review provides a valuable source for current knowledge about nutritional and bioactive compositions, as well as the relationship of its biologically active components with beneficial and functional effects on human health, through scientifically proven information. By harnessing the rich properties of ora-pro-nobis fruit, we can pave the way for further development of functional foods, as well as its applications in the nutraceutical, cosmetic, and pharmaceutical industries.Frutos exóticos como os da ora-pro-nóbis desempenham um papel importante na nutrição humana tornando-se excelente base para dietas de baixo teor calórico. Altamente valorizado por seu sabor, aroma e cor únicos, pesquisas recentes mostram que os frutos da ora-pro-nóbis podem ser ricos em muitos compostos nutricionais e bioativos. Com a crescente popularidade deste fruto em mercados econômicos é importante ter uma referência abrangente por seus benefícios nutricionais e bioativos. Esta revisão fornece uma fonte valiosa para o conhecimento atual sobre a composição nutricional, bioativa e a relação dos seus componentes biologicamente ativos com efeitos benéficos e funcionais na saúde humana, através de informações cientificamente comprovadas e desenvolvimento adicional de frutos de ora-pro-nóbis para alimentos funcionais, bem como aplicações nas indústrias nutracêuticas, cosméticas e farmacêuticas

Avanços no Desenvolvimento Motor e Interação Social de Crianças com TEA Efeitos do Exercício Físico

Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition associated with various causes. It is characterized by deficits in social interaction, emotional reciprocity, communication, motor skills, and cognitive functions. Physical activity has been studied as a complementary intervention for patients with ASD, providing significant benefits. Among these benefits are improvements in social interaction, communication, sports skills, and reduction of stereotyped behaviors. Various forms of physical activity have been investigated for their effectiveness in enhancing motor skills in individuals with ASD. In addition to traditional practices like swimming and dancing, an interesting alternative has emerged: exergames. These games, which require interaction between the participant and the video game, serve as a playful way to engage in physical activity. Through exergames, it is possible to increase adherence among patients with ASD, overcoming the low participation observed in other physical activities. In summary, research highlights the relevance of physical activity as a complementary intervention in the treatment of patients with ASD, contributing to the development of motor skills, reduction of stereotyped behaviors, and emotional regulation.O TEA é um transtorno complexo do neurodesenvolvimento associado a diversas etiologias e caracterizado por déficits na interação social, reciprocidade emocional, comunicação, habilidades motoras e funções cognitivas. A atividade física tem sido estudada como uma intervenção complementar para pacientes com TEA, proporcionando benefícios significativos, como a melhora das habilidades de interação social, comunicação, habilidades esportivas e comportamentos estereotipados. Diversas atividades físicas vêm sendo estudadas quanto a sua eficácia para o aprimoramento das habilidades motoras, como a natação e a dança. No entanto, a baixa adesão de participantes com TEA às atividades físicas é um fator que dificulta o seu uso como tratamento complementar. O exergame, que são jogos que necessitam da interação entre o participante e o vídeo game, funcionam como uma forma lúdica de prática de atividade física e podem aumentar a adesão dos pacientes com TEA. Em suma, o artigo destaca a importância da atividade física como uma intervenção complementar para pacientes com TEA, proporcionando benefícios significativos para a melhora das habilidades motoras, comportamentos estereotipados e regulação emocional

Estudo inicial sobre a evolução do novo CORONAVÍRUS (SARS-COV-2) no estado do Pará (Brasil), no período entre 17/03/2020 e 06/04/2020.

O presente artigo apresenta o estudo inicial sobre a evolução do novo coronavírus (SARS-CoV-2) no estado do Pará, desde a confirmação do primeiro infectado no dia 18/03/2020 até o dia 06/04/2020.O estudo apresenta também um modelo matemático para estimar o número de infectados até o dia 06/05/2020. Os resultados mostram que o modelo é confiável para predições de curto prazo, cuja evolução pode ser de 1 infectado em 18/03/2020 a 761 infectados em 18/04/2020.This paper presents the initial study on the evolution of Coronavirus (SARS-CoV-2) in the state of Pará, from the confirmation of the first infected on 18/03/2020 until 06/04/2020. The study also presents a mathematical model for estimating the number of infected by 06/05/2020. The results show that the model is reliable for short-term predictions, whose evolution can be from 01 infected on 03/18/2020 to 761 infected on 18/04/2020

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio

As manifestações clínicas do portador de paralisia facial

Introdução: A paralisia facial e um sintoma de um transtorno de base resultante em imobilidade e incapacidade de executar a mímica facial e a expressão emotiva. São várias as etiologias deste acometimento, sendo a classificação em paralisia facial periférica, representada classicamente pela paralisia de Bell e a central, pelo acidente vascular encefálico, adotada para auxiliar na investigação e seguimento clínico adequado. Objetivo: Descrever sobre a paralisia facial, com foco em características clínicas que propiciem ao diagnóstico precoce, medidas terapêuticas e restauração imediata. Metodologia: Revisão narrativa que selecionou artigos disponibilizados na íntegra publicados no recorte temporal de 2008 até 2022. Resultados: Dos 10 artigos incluídos neste estudo, todos realizaram uma ampla análise sobre a temática, a qual propiciou a disseminação de informações atualizadas sobre conceito, diagnóstico diferencial entre duas condições clínicas opostas resultantes em paralisia facial, manifestações, avaliação clínica e manejo adequado. Conclusão: Estudos ainda urgem em ser feitos no intuito de orientar melhor os profissionais e a comunidade a respeito da paralisia facial e a importância que possui o acompanhamento e seguimento precoce. Destarte,

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost