An X-ray Survey of Galaxies in Pairs

Results are reported from the first survey of X-ray emission from galaxies in pairs. The sample consists of fifty-two pairs of galaxies from the Catalog of Paired Galaxies Karachentsev (1972) whose coordinates overlap ROSAT Position Sensitive Proportional Counter pointed observations. The mean observed log l_x for early-type pairs is 41.35 +/-0.21 while the mean log l_x predicted using the l_x-l_b relationship for isolated early-type galaxies is 42.10 +/-0.19. With 95% confidence, the galaxies in pairs are underluminous in the X-ray, compared to isolated galaxies, for the same l_b. A significant fraction of the mixed pair sample also appear similarly underluminous. A spatial analysis shows that the X-ray emission from pairs of both types typically has an extent of ~10 - 50 kpc, much smaller than group intergalactic medium and thus likely originates from the galaxies. CPG 564, the most X-ray luminous early-type pair, 4.7x10^42 ergs/sec, is an exception. The extent of it's X-ray emission, >169 kpc, and HWHM, ~80 kpc, is comparable to that expected from an intergalactic medium. The sample shows only a weak correlation, ~81% confidence, between l_x and l_b, presumably due to variations in gas content within the galaxies. No correlation between l_x and the pair velocity difference, separation, or far-infrared luminosity is found though the detection rate is low, 22%.Comment: 40 pages, 6 jpg figures, ApJ (in press

An evaluation of Mesozoic rift-related magmatism on the margins of the Labrador Sea: Implications for rifting and passive margin asymmetry

The Labrador Sea is a small (∼900 km wide) ocean basin separating southwest Greenland from Labrador, Canada. It opened following a series of rifting events that began as early as the Late Triassic or Jurassic, culminating in a brief period of seafloor spreading commencing by polarity chron 27 (C27; Danian) and ending by C13 (Eocene-Oligocene boundary). Rift-related magmatism has been documented on both conjugate margins of the Labrador Sea. In southwest Greenland this magmatism formed a major coast-parallel dike swarm as well as other smaller dikes and intrusions. Evidence for rift-related magmatism on the conjugate Labrador margin is limited to igneous lithologies found in deep offshore exploration wells, mostly belonging to the Alexis Formation, along with a postulated Early Cretaceous nephelinite dike swarm (ca. 142 Ma) that crops out onshore, near Makkovik, Labrador. Our field observations of this Early Cretaceous nephelinite suite lead us to conclude that the early rift-related magmatism exposed around Makkovik is volumetrically and spatially limited compared to the contemporaneous magmatism on the conjugate southwest Greenland margin. This asymmetry in the spatial extent of the exposed onshore magmatism is consistent with other observations of asymmetry between the conjugate margins of the Labrador Sea, including the total sediment thickness in offshore basins, the crustal structure, and the bathymetric profile of the shelf width. We propose that the magmatic and structural asymmetry observed between these two conjugate margins is consistent with an early rifting phase dominated by simple shear rather than pure shear deformation. In such a setting Labrador would be the lower plate margin to the southwest Greenland upper plate

Explaining the rise of 'human rights' in analyses of Sino-African relations

Popular perceptions of China and its global role are often shaped by two words: 'made in'. Yet this vision of China that focuses primarily on Beijing as a coming economic superpower is relatively new, and it is not that long ago that two other words tended to dominate debates on and discourses of China: 'human rights'. To be sure, real interest in human rights in China was never the only issue in other states' relations with China, nor consistently pursued throughout the years (Nathan, 1994). Nor did human rights totally subsequently disappear from the political agenda.1 Nevertheless, the rhetorical importance of human rights - perhaps best epitomised by the narrow defeat of resolutions condemning Chinese policy in 1995 at the Human Rights Council in Geneva - stands in stark contrast to the relative silence thereafter as the bottom line of most states' relations with Beijing took on ever greater economic dimensions

The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of prostate carcinoma.

Prostate cancer is the most commonly diagnosed malignancy and second leading cause of cancer death among men in the United States. In recent years, several new agents, including cancer immunotherapies, have been approved or are currently being investigated in late-stage clinical trials for the management of advanced prostate cancer. Therefore, the Society for Immunotherapy of Cancer (SITC) convened a multidisciplinary panel, including physicians, nurses, and patient advocates, to develop consensus recommendations for the clinical application of immunotherapy for prostate cancer patients. To do so, a systematic literature search was performed to identify high-impact papers from 2006 until 2014 and was further supplemented with literature provided by the panel. Results from the consensus panel voting and discussion as well as the literature review were used to rate supporting evidence and generate recommendations for the use of immunotherapy in prostate cancer patients. Sipuleucel-T, an autologous dendritic cell vaccine, is the first and currently only immunotherapeutic agent approved for the clinical management of metastatic castrate resistant prostate cancer (mCRPC). The consensus panel utilized this model to discuss immunotherapy in the treatment of prostate cancer, issues related to patient selection, monitoring of patients during and post treatment, and sequence/combination with other anti-cancer treatments. Potential immunotherapies emerging from late-stage clinical trials are also discussed. As immunotherapy evolves as a therapeutic option for the treatment of prostate cancer, these recommendations will be updated accordingly

The languages of peace during the French religious wars

The desirability of peace was a common topos in sixteenth-century political rhetoric, and the duty of the king to uphold the peace for the benefit of his subjects was also a long-established tradition. However, the peculiar circumstances of the French religious wars, and the preferred royal policy of pacification, galvanized impassioned debate among both those who supported and those who opposed confessional coexistence. This article looks at the diverse ways in which peace was viewed during the religious wars through an exploration of language and context. It draws not only on the pronouncements of the crown and its officials, and of poets and jurists, but also on those of local communities and confessional groups. Opinion was not just divided along religious lines; political imperatives, philosophical positions and local conditions all came into play in the arguments deployed. The variegated languages of peace provide a social and cultural dimension for the contested nature of sixteenth-century French politics. However, they could not restore harmony to a war-torn and divided kingdom

Impact of identity politics on education in Pakistan: a comparison between Balochistan and Punjab

This research paper examines the impact of ethnic identity based politics on education in Pakistan through in-depth interviews with young professionals from Balochistan and Punjab. Findings suggest that there is the Punjabi-dominated power structure results in an unequal allocation of financial resources, whereby Balochistan lacks the financial resources to invest in education development. In addition, political instability caused by unprecedented ethnic strife contributes towards poor quality education, which, as a result, adversely impacts a Balochi's future course of life. On the other hand, Punjabis are at an advantage in the public arena because of their robust educational foundation

Design of a Morphing Wing-tip

An initial design of a morphing wing-tip for a Regional Jet aircraft is developed and evaluated. The adaptive wing-tip concept is based upon a chiral type internal structure, enabling controlled cant angle orientation, camber and twist throughout the flight envelope. A baseline Turbo-Fan Aircraft configuration model is used as the benchmark to assess the device. CFD based aerodynamics are used to evaluate the required design configurations for the device at different points across the flight envelope in terms of lift/drag and bending moment distribution along the span, complemented by panel method based gust load computations. Detailed studies are performed to show how the chiral structure can facilitate the required shape changes in twist, camber and cant. Actuator requirements and limitations are assessed, along with an evaluation of the aerodynamic gains from the inclusion of the device versus power and weight penalties. For a typical mission it was found that savings of around 2% in fuel weight are possible using the morphing wing-tip device. A similar reduction in weight due to passive gust loads alleviation is also possible with a slight change of configuration

Role of blood pressure in mediating carotid artery dilation in response to sympathetic stimulation in healthy, middle-aged individuals

Objectives: Carotid artery diameter responses to sympathetic stimulation, i.e., carotid artery reactivity (CAR), represent a novel test of vascular health and relates to cardiovascular disease (CVD)/risk. This study aims to understand the relationship between the increase in blood pressure and carotid artery diameter response during the CAR-test in healthy, middle-aged men. Methods: Sample consisted of 40 normotensive men (aged 31–59 years) with no history of CVD of currently taking medication. Noninvasive ultrasound was used to measure carotid artery diameter during the cold pressor test (CPT), with CAR% being calculated as the relative change from baseline (%). Mean arterial pressure (MAP) was measured with beat-to-beat blood pressure recording. Results: CAR% was 4.4 ± 5.4%, peaking at 92 ± 43 seconds. MAP increased from 88 ± 9 mmHg to 110 ± 15 mmHg, peaked at 112 ± 38 seconds, which was significantly later than the diameter peak (P = 0.04). The correlation between resting MAP and CAR% was weak (r = 0.209 P = 0.197). Tertiles based on resting MAP or MAP-increase revealed no significant differences between groups in subject characteristics including age, body mass index, or CAR% (all P > 0.05). Subgroup analysis of individuals with carotid constriction (n = 6) vs. dilation (n = 34), revealed no significant difference in resting MAP or increase in MAP (P = 0.209 and 0.272, respectively). Conclusion: Our data suggest that the characteristic increase in MAP during the CPT does not mediate carotid artery vasomotion

The discursive construction of childhood and youth in AIDS interventions in Lesotho's education sector: Beyond global-local dichotomies

This is the post-print version of this article. The definitive, peer-reviewed and edited version of this article is published in Environment and Planning D,Society and Space 28(5) 791 – 810, 2010, available from the link below. Copyright @ 2010 Pion.In southern Africa interventions to halt the spread of AIDS and address its social impacts are commonly targeted at young people, in many cases through the education sector. In Lesotho, education-sector responses to AIDS are the product of negotiation between a range of ‘local’ and ‘global’ actors. Although many interventions are put forward as government policy and implemented by teachers in schools, funding is often provided by bilateral and multilateral donors, and the international ‘AIDS industry’—in the form of UN agencies and international NGOs—sets agendas and makes prescriptions. This paper analyses interviews conducted with policy makers and practitioners in Lesotho and a variety of documents, critically examining the discourses of childhood and youth that are mobilised in producing changes in education policy and practice to address AIDS. Focusing on bursary schemes, life-skills education, and rights-based approaches, the paper concludes that, although dominant ‘global’ discourses are readily identified, they are not simply imported wholesale from the West, but rather are transformed through the organisations and personnel involved in designing and implementing interventions. Nonetheless, the connections through which these discourses are made, and children are subjectified, are central to the power dynamics of neoliberal globalisation. Although the representations of childhood and youth produced through the interventions are hybrid products of local and global discourses, the power relations underlying them are such that they, often unintentionally, serve a neoliberal agenda by depicting young people as individuals in need of saving, of developing personal autonomy, or of exercising individual rights.RGS-IB