6,291 research outputs found
Une excentrique au coeur de lâindustrie : Ray Lewis et le Canadian Moving Picture Digest
Ray Lewis fut, de 1918 Ă 1954, la rĂ©dactrice en chef du Canadian Moving Picture Digest, le premier journal corporatif relatif Ă lâindustrie cinĂ©matographique canadienne. La personnalitĂ© et le parcours exceptionnels de Lewis peuvent expliquer sa prĂ©sence â en apparence inusitĂ©e â Ă la tĂȘte dâune publication sâadressant Ă une industrie essentiellement masculine. Lewis milita ardemment dans les pages du Digest pour lâorganisation et la dĂ©fense des exploitants indĂ©pendants, de mĂȘme que pour la crĂ©ation dâune culture nationale canadienne se dĂ©marquant du modĂšle amĂ©ricain.In 1918, Ray Lewis became editor of Canadaâs principal film trade journal, the Canadian Moving Picture Digest. She soon owned it, too, and stayed in charge until her death in 1954. If it was uncommon enough for a woman to be journalist and editor, it was truly exceptional for a woman to be in a powerful position in the film industry. Lewisâ strong character carried into her work as self-appointed protector of Canadian exhibitorsâ independence. She used the Digest to agitate against Hollywood control, and tried to promote a distinctly Canadian culture of movie-going
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Ray Lewis
For nearly four decades, Ray Lewis was one of the most vocal representatives of the Canadian film industry. The trade journal she edited from the late 1910s until the mid-1950s, the Canadian Moving Picture Digest, kept the nationâs film exhibitors informed on a wide variety of topics. It also permitted Lewis to mount campaigns dealing with some of the most vital issues of the day, such as the defense of independent exhibitors and the quest for a distinctly Canadian film culture
Macrophage transactivation for chemokine production identified as a negative regulator of granulomatous inflammation using agent-based modeling
Cellular activation in trans by interferons, cytokines and chemokines is a commonly recognized mechanism to amplify immune effector function and limit pathogen spread. However, an optimal host response also requires that collateral damage associated with inflammation is limited. This may be particularly so in the case of granulomatous inflammation, where an excessive number and / or excessively florid granulomas can have significant pathological consequences. Here, we have combined transcriptomics, agent-based modeling and in vivo experimental approaches to study constraints on hepatic granuloma formation in a murine model of experimental leishmaniasis. We demonstrate that chemokine production by non-infected Kupffer cells in the Leishmania donovani-infected liver promotes competition with infected KCs for available iNKT cells, ultimately inhibiting the extent of granulomatous inflammation. We propose trans-activation for chemokine production as a novel broadly applicable mechanism that may operate early in infection to limit excessive focal inflammation
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Climate adaptation by crop migration.
Many studies have estimated the adverse effects of climate change on crop yields, however, this literature almost universally assumes a constant geographic distribution of crops in the future. Movement of growing areas to limit exposure to adverse climate conditions has been discussed as a theoretical adaptive response but has not previously been quantified or demonstrated at a global scale. Here, we assess how changes in rainfed crop area have already mediated growing season temperature trends for rainfed maize, wheat, rice, and soybean using spatially-explicit climate and crop area data from 1973 to 2012. Our results suggest that the most damaging impacts of warming on rainfed maize, wheat, and rice have been substantially moderated by the migration of these crops over time and the expansion of irrigation. However, continued migration may incur substantial environmental costs and will depend on socio-economic and political factors in addition to land suitability and climate
Real-time forecasts of flood hazard and impact: some UK experiences
Major UK floods over the last decade have motivated significant technological and scientific advances in operational flood forecasting and warning. New joint forecasting centres between the national hydrological and meteorological operating agencies have been formed that issue a daily, national Flood Guidance Statement (FGS) to the emergency response community. The FGS is based on a Flood Risk Matrix approach that is a function of potential impact severity and likelihood. It has driven an increased demand for robust, accurate and timely forecast and alert information on fluvial and surface water flooding along with impact assessments. The Grid-to-Grid (G2G) distributed hydrological model has been employed across Britain at a 1km resolution to support the FGS. Novel methods for linking dynamic gridded estimates of river flow and surface runoff with more detailed offline flood risk maps have been developed to obtain real-time probabilistic forecasts of potential impacts, leading to operational trials. Examples of the national-scale G2G application are provided along with case studies of forecast flood impact from (i) an operational Surface Water Flooding (SWF) trial during the Glasgow 2014 Commonwealth Games, (ii) SWF developments under the Natural Hazards Partnership over England & Wales, and (iii) fluvial applications in Scotland
Psychosocial Characteristics and Obstetric Health of Women Attending a Specialist Substance Use Antenatal Clinic in a Large Metropolitan Hospital
Objective. This paper reports the findings comparing the obstetrical health, antenatal care, and psychosocial characteristics of pregnant women with a known history of substance dependence (n = 41) and a comparison group of pregnant women attending a general antenatal clinic (n = 47). Method. Face-to-face interviews were used to assess obstetrical health, antenatal care, physical and mental functioning, substance use, and exposure to violence. Results. The substance-dependent group had more difficulty accessing antenatal care and reported more obstetrical health complications during pregnancy. Women in the substance-dependent group were more likely to report not wanting to become pregnant and were less likely to report using birth control at the time of conception. Conclusions. The profile of pregnant women (in specialised antenatal care for substance dependence) is one of severe disadvantage and poor health. The challenge is to develop and resource innovative and effective multisectoral systems to educate women and provide effective care for both women and infants
Accountability, Strategy, and International Non-Governmental Organizations
Increased prominence and greater influence expose international non-governmental development and environmental organizations (INGOs) to increased demands for accountability from a wide variety of stakeholdersdonors, beneficiaries, staffs, and partners among others. This paper focuses on developing the concept of INGO accountability, first as an abstract concept and then as a strategic idea with very different implications for different INGO strategies. We examine those implications for INGOs that emphasize service delivery, capacity-building, and policy influence. We propose that INGOs committed to service delivery may owe more accountability to donors and service regulators; capacity-building INGOs may be particularly obligated to clients whose capacities are being enhanced; and policy influence INGOs may be especially accountable to political constituencies and to influence targets. INGOs that are expanding their activities to include new initiatives may need to reorganize their accountability systems to implement their strategies effectively. This publication is Hauser Center Working Paper No. 7. The Hauser Center Working Paper Series was launched during the summer of 2000. The Series enables the Hauser Center to share with a broad audience important works-in-progress written by Hauser Center scholars and researchers
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